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All Journal HAYATI Journal of Biosciences Jurnal Farmasi Klinik Indonesia Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JMM (Jurnal Masyarakat Mandiri) Window of Health : Jurnal Kesehatan JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung Jurnal Mandala Pharmacon Indonesia INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Kedokteran Hewan Jurnal Farmasi Indonesia Media Farmasi
Muh. Akbar Bahar
Departemen Farmasi, Fakultas Farmasi, Universitas Hasanuddin, Makassar, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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THE EFFECTS OF SIMVASTATIN, ROSUVASTATIN, AND FENOFIBRATE ON THE BODY WEIGHT AND LIPID PROFILES OF FEMALE RATS TREATED WITH ORAL CONTRACEPTIVES AND A HIGH-FAT DIET Putri, Dwi Anggara; Djabir, Yulia Yusrini; Bahar, Muhammad Akbar; Alam, Gemini; Rahman, Latifah; Aswad, Muhammad; Arsyad, Muhammad Aryadi
Jurnal Kedokteran Hewan Vol 16, No 3 (2022): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v16i3.22196

Abstract

This study aimed to compare the effects of simvastatin, rosuvastatin, and fenofibrate therapies on the body weight and lipid profiles of the female rats receiving a combination of oral contraceptives (COC) and a high-fat diet (HFD). Twenty female Wistar rats (130-200 g) were divided equally into four groups. The rats received a standard diet for seven days, and their baseline lipid profiles were analyzed. All rats also received COC containing 15.1 g/kg levonorgestrel/3.1 g/kg estradiol with HFD for 60 days. Starting on day 31, the rats were given the respected treatment. The control group received the vehicle, whereas the others were treated with either simvastatin (2.1 mg/kg), rosuvastatin (0.5 mg/kg), or fenofibrate (8.2 mg/kg). Blood samples were taken on days 30 and 60. The results showed that the administration of COC+HFD and vehicle for 30 days increased the rats body weight and dyslipidemia, characterized by a significant decrease in Low-Density Lipoprotein (HDL) and an increase in total cholesterol (TC) and triglycerides (TG) levels (P0.05). Among the treatments, only fenofibrate was found to be able to prevent a significant weight gain in rats. Both fenofibrate and rosuvastatin inhibited a significant rise in TG and TC levels. Meanwhile, the simvastatin administration failed to do the same. Although statistically insignificant, all treatments increased rats HDL levels. Thus, it can be concluded fenofibrate was the most effective treatment among all in reducing weight gain and improving the lipid profile of dyslipidemic rats induced by oral contraceptives and a high-fat diet.
Hubungan Level Depresi terhadap Kepatuhan Minum Obat Pasien Diabetes Melitus Tipe 2 di Puskesmas Kota Makassar Utami, Mutiara Cahya; Tangdilintin, Frederika; Anggriani, A.; Bahar, Muh. Akbar
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.789

Abstract

Diabetes Melitus Tipe 2 (DMT2) merupakan salah satu penyakit kronis yang memiliki prevalensi cukup tinggi. Kondisi depresi pada pasien dapat memengaruhi tingkat kepatuhan dalam mengonsumsi obat serta berdampak buruk pada pengendalian kadar glukosa darah. Penelitian ini bertujuan untuk mengkaji hubungan antara tingkat depresi dan kepatuhan pengobatan pada penderita DMT2 di beberapa Puskesmas Kota Makassar. Metode penelitian menggunakan desain cross-sectional dengan melibatkan 150 pasien dari empat puskesmas. Tingkat depresi dinilai menggunakan instrumen Beck Depression Inventory-II (BDI-II), sementara kepatuhan minum obat diukur dengan Medication Adherence Rating Scale (MARS). Analisis data dilakukan melalui uji regresi logistik multivariat. Hasil penelitian menunjukkan bahwa sebagian besar responden (84,7%) memiliki tingkat kepatuhan sedang, sedangkan 15,3% termasuk dalam kategori kepatuhan tinggi. Berdasarkan tingkat depresi, 24,7% pasien berada dalam kategori normal, 30% mengalami gangguan suasana hati ringan, 17,3% berada pada ambang depresi, dan 28% mengalami depresi ringan hingga sedang. Analisis bivariat mengungkapkan bahwa lama pendidikan memiliki hubungan signifikan dengan kepatuhan pengobatan. Sementara itu, analisis multivariat menunjukkan adanya hubungan yang signifikan antara tingkat depresi dan kepatuhan minum obat (aOR: 0,156; 95% CI: 0,038–0,636; p = 0,010). Temuan ini mengindikasikan bahwa depresi berperan penting dalam memengaruhi kepatuhan pengobatan pasien DMT2. Oleh karena itu, penanganan depresi perlu menjadi pertimbangan dalam tata laksana DMT2 guna meningkatkan kepatuhan terapi dan kontrol glikemik yang lebih baik.
Tingkat Kepuasan Pasien Diabetes Mellitus Tipe 2 Terhadap Pelayanan Tenaga Kefarmasian Di Puskesmas Moncongloe Kabupaten Maros Andi Dian Fitri Amoer; Frederika Tangdilintin; Anshar Saud; Muh. Akbar Bahar
Media Farmasi Vol 21 No 2 (2025): Media Farmasi Edisi Oktober 2025
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v21i2.1384

Abstract

ABSTRACT Diabetes mellitus (DM) is one of the serious health problems and the biggest cause of death in the world. One of the districts that has the largest number of people with diabetes mellitus in South Sulawesi Province is Maros Regency. Pharmacists play a very important role in the therapeutic process of DM patients to improve the quality of life of patients. Objective. This study aims to determine the level of patient satisfaction based on perceptions of pharmaceutical services at the Moncongloe Health Center, Maros Regency. Methods. This study is a quantitative study with cross sectional method. This research instrument is a questionnaire adopted from previous studies that have been proven valid and reliable. This research was conducted at the Moncongloe Health Center, Maros Regency, South Sulawesi Province in January 2024. Results. This study shows that respondents gave a satisfied perception of the overall service of pharmaceutical personnel with a total percentage of 86%. In the aspect of prescription screening, the dominant patient was satisfied with a percentage of 43%; the aspect of drug preparation 66%; the aspect of drug information communication and education 46.6%; drug monitoring 42.8% of each patient was satisfied. Conclusion. The overall level of patient satisfaction with the perception of pharmaceutical personnel services at the Moncongloe Health Center, Maros Regency is 86% which is included in the satisfied category.
Penerapan Pelayanan Informasi Obat Di Beberapa Puskesmas Kabupaten Gowa St. Atifah Ananda Usman; Alghifary Anas Achmad; Andi Anggriani; Muh. Akbar Bahar
Media Farmasi Vol 21 No 2 (2025): Media Farmasi Edisi Oktober 2025
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v21i2.1413

Abstract

Drug information services (DIS) are activities carried out by pharmaceutical personnel to provide accurate, clear, and up-to-date information about drugs to patients, doctors, nurses, and other health professionals. This research aims to determine the implementation of drug information services in several Community Health Centers in the Gowa Regency area. This research uses a cross-sectional study method. Research subjects who met the inclusion criteria were 18 years of age or older, able to read and write, had received treatment at least three times, and were willing to participate in the research. This research was conducted at four health centers in four regions of Gowa Regency: Parangloe Health Center representing the North region, Tamaona Health Center representing the East region, Batumalonro Health Center representing the South region, and Bontonompo Health Center representing the West region. This research was carried out from December 2023 to January 2024. The application of drug information services, in the form of providing information on drug doses, was 90.3%; drug names, 76.5%; how to use, 72.8%; indications, 72.5%; dosage forms, 70.5%; storage, 35.8%; interactions, 32.8%; side effects, 27.5%; contraindications, 27.5%; and stability, 25.8%. It can be concluded that the implementation of drug information services in several health centers in the Gowa Regency area has not been carried out optimally. Keywords: DIS, Patient, Pharmacist, Gowa Regency, Drug
Faktor-Faktor yang Mempengaruhi Intensi Masyarakat Untuk Mengikuti Vaksinasi Covid-19 Dosis Lengkap di Kota Makassar Risman Harnas; Anshar Saud; Muh. Akbar Bahar
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 16 No 2 (2024): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v16i2.224

Abstract

The control of the COVID-19 pandemic is influenced by the effective acceptance of vaccines. This study aims to identify the factors affecting the willingness of the public to receive the complete dose of COVID-19 vaccine in the city of Makassar. A cross-sectional research approach was employed, utilizing a questionnaire consisting of demographic information, perceptions of the severity and vulnerability to COVID-19, as well as barriers and benefits of COVID-19 vaccination, which were distributed online in Makassar City. Multivariate logistic regression analysis was used to identify independent factors influencing the intention of the public to receive the full dose (two doses) of the vaccine. A total of 310 respondents participated in this study. Respondents who perceived a high level of disease severity (aOR= 3.39; 95% CI: 1.41 – 8.14) had a higher likelihood of receiving full COVID-19 vaccination, while respondents with a perception of high access barriers to vaccination had a lower likelihood of receiving full COVID-19 vaccination (aOR= 0.18; 95% CI: 0.07 – 0.45). In this study, the intention to accept full COVID-19 vaccination was influenced by perceptions of disease severity and perceived access barriers to vaccination. The implementation of the COVID-19 immunization program by healthcare providers and local governments should incorporate various vaccination education strategies tailored to patients' health beliefs.
PENYULUHAN KEAMANAN MAKANAN DAN KANTIN SEHAT PADA SISWA SD MENGGUNAKAN BUKU CERITA Bachtiar Rifai Pratita Ihsan; Anggita Rosiana Putri; Luthfi Ahmad Muchlashi; Muh. Akbar Bahar
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 2 (2025): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i2.29574

Abstract

Abstrak: Makanan dan jajanan yang dikonsumsi siswa sekolah dasar dapat memberikan dampak buruk terhadap kesehatan. Faktor penyebabnya adalah cemaran makanan yang terjadi selama proses pembuatan, penyajian atau penyimpanan makanan. Monitoring batasan harian konsumsi jajanan kemasan perlu diperhatikan karena adanya Bahan Tambahan Makanan (BTM) pada makanan kemasan. Tujuan kegiatan ini adalah meningkatkan pengetahuan siswa Sekolah Dasar (SD) mengenai keamanan makanan dan kantin sehat. Kegiatan penyuluhan dilakukan di dua sekolah dasar menggunakan media buku cerita edukasi yang menarik dengan gaya bahasa interaktif siswa sekolah SD. Kegiatan penyuluhan dilaksanakan di SDN 1 Watugede Singosari dan SD Islam Terpadu Robbani Watugede Singosari Kabupaten Malang..Hasil kegiatan menunjukkan kenaikan pemahaman siswa SD adalah 35% berdasarkan peningkatan nilai Pre-Test dan Post-Test. Sebanyak 87% Siswa dari kedua sekolah mampu meraih nilai Post-Test dengan kriteria nilai minimal 70. Pengetahuan siswa SD mengenai keamanan makanan dan kantin sehat meningkat secara signifikan setelah penyuluhan menggunakan buku cerita.Abstract: The consumption of food and snacks by elementary school students can negatively affect their health. The primary cause is contamination during food production, serving, or storage. Monitoring the daily consumption of packaged snacks is essential due to the presence of food additives. The aim of this activity is to increase elementary school students’ knowledge about food safety and healthy canteens. The counseling sessions were conducted in two elementary schools using an educational storybook written in an interactive and engaging style suitable for elementary school students. The Counseling activity were carried out at SDN 1 Watugede and SDIT Robbani Watugede Singosari Kabupaten Malang. The results of the activity showed a 35% increase in the student’s knowledge, as indicated by improvements in the Pre-Test and Post-Test scores. Additionally, 87% of students from both schools achieved Post-Test scores of at least 70. The elementary school students’ knowledge about food safety and healthy canteens significantly increased after counseling using a story book. 
HUBUNGAN PENGETAHUAN IBU HAMIL DAN KEPATUHAN KONSUMSI TABLET TAMBAH DARAH DI KOTA MAKASSAR: The Association Bertween Pregnant Women’s Knowledge And Adherence To Iron Supplementation Tablet Consumption In Makassar City Weldhea Putri Maylani; Hardiyanti Syarif; Muhammad Akbar Bahar
JFL : Jurnal Farmasi Lampung Vol. 15 No. 1 (2026): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/ff6s0m12

Abstract

Abstract Preterm birth is a leading cause of mortality among children under five years old, with maternal anemia as one of its major risk factors. Limited knowledge and poor adherence among pregnant women in consuming iron supplementation tablets may increase the risk of anemia, which contributes to preterm birth. This study aimed to analyze the association between pregnant women’s knowledge levels and their adherence to iron supplementation tablets in preventing preterm birth at community health centers in Makassar City. This cross-sectional study involved 117 pregnant women from four community health centers in Makassar (Sudiang, Tamalanrea, BTN Antara, and Kassi-Kassi). Data were collected using a knowledge questionnaire and the Medication Adherence Rating Scale (MARS). The results showed that 58.1% of pregnant women were adherent to iron supplementation tablets. Bivariate analysis indicated significant associations between education duration of more than 12 years (OR: 4.911; 95% CI: 1.847–13.057; p=0.001) and employment status (OR: 2.622; 95% CI: 1.064–6.461; p=0.036) with adherence. Multivariate analysis revealed that a good level of knowledge was significantly associated with adherence (AOR: 6.613; 95% CI: 1.484–29.456; p=0.013). Higher knowledge levels were associated with better adherence to iron supplementation tablets. Keywords:  Adherence, Iron, Suplementation Tablets, Knowledge, Pregnant Women, Preterm Birth
Co-Authors Abdul Rahim Abdul Rahim Alghifary Anas Achmad Aliyah Putranto Amelia Ramadhani Anshar Andi Anggriani Andi Anggriani Andi Dian Fitri Amoer Andi Dian Permana Anggita Rosiana Putri Anggriani, A. Anshar Saud Anshar Saud Arsyad, Muhammad Aryadi Bachtiar Rifai Pratita Ihsan Bob Wilffert Dini Ayu Ariastiwi B Djabir, Yulia Yusrini Elly Wahyudin Firzan Nainu Frederika Tangdilintin Gemini Alam Gemini Alam Habibie Habibie Harapan Harapan Hardiyanti Syarif Ikliptikawati, Dini Kurnia Innal Saitis Ismail Ismail Jamhari Jamhari Latifah Rahman Luthfi Ahmad Muchlashi Marianti A. Manggau Marianti A. Manggau Marianti A.Manggau Matra Novalia Palipadang Mufidah Mufidah Muhammad Aswad Muhammad Aswad Muhammad Aswad Muhammad Raihan Nana Juniarti Natsir Djide Putri, Dwi Anggara Risman Harnas sakiya syahrir sudirman Sandra Aulia Mardikasari St. Atifah Ananda Usman Subehan Lallo Suparman Suparman Tangdilintin, Frederika Usmar Usmar Utami, Mutiara Cahya Weldhea Putri Maylani Wenry Deston Latif Yani Pratiwi Yayu Mulsiani Evary Yayuk S. Rahayu Yulia Yusrini Djabir