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All Journal International Journal of Public Health Science (IJPHS) Jurnal Gizi dan Pangan BALI MEDICAL JOURNAL (BMJ) journal of internal medicine INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES E-Jurnal Medika Udayana Journal of Biomedicine and Translational Research WMJ (Warmadewa Medical Journal) The Indonesian Biomedical Journal Public Health of Indonesia Molecular and Cellular Biomedical Sciences (MCBS) JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Pharmasipha Jurnal Penyakit Dalam Udayana Jurnal Pendidikan dan Konseling Jurnal Cahaya Mandalika International Journal of Industrial Engineering and Engineering Management Journal of Global Pharma Technology Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA) Jurnal Kedokteran Hewan Journal Pharmaceutical Science and Application (JPSA)
I Made Bakta
Universitas Bali Internasional
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary Other

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PERAN OVISIDAL HERBAL SERBUK BIJI PEPAYA MATANG DAN ALBENDAZOL TERHADAP DAYA BEREMBRIO TELUR CACING Ascaris suum SECARA IN VIVO Ardana, Ida Bagus Komang; Bakta, I Made; Damriyasa, I Made
Jurnal Kedokteran Hewan Vol 6, No 1 (2012): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v6i1.353

Abstract

Telah dilakukan penelitian untuk mengetahui pemberian herbal serbuk biji pepaya matang secara oral pada babi ascariasis terhadap dayaberembrio telur cacing pada tinja dan pada uterus cacing yang keluar dari babi yang diobati tersebut. Pada percobaan ini sebanyak 24 ekor babi Landrace betina dengan bobot badan 10-15 kg, umur 15 minggu yang terinfeksi cacing Ascaris suum (A. suum) secara alami, dengan egg per gram (EPG) berkisar 250-2500 butir. Babi tersebut dibagi menjadi empat kelompok perlakuan (P0, P1, P2, dan P3) masing-masing terdiri dari 6 ekor. Kelompok P1 dan kelompok P2 mendapat perlakuan dengan herbal serbuk biji pepaya matang per oral dengan dosis masing-masing 1 dan 3 g/kg bobot badan (P2) selama 3 hari berturut-turut. Kelompok P3 mendapat perlakuan dengan albendazol dosis 0,5 mg/kg bobot badan (Zodalben 0,04 ml/kg bobot badan) sedangkan kelompok P0 bertindak sebagai kontrol tanpa pengobatan. Hasil penelitian ini menunjukkan bahwa pengobatan dengan herbal serbuk biji pepaya matang pada babi ascariasis ternyata mampu menurunkan daya berembrio telur cacing dalam tinja babi dan dalam uterus cacing secara efektif sehingga dapat digunakan untuk pengendalian askariasis pada babi.
HUBUNGAN TINGKAT PENGETAHUAN TERHADAP PERILAKU DALAM SWAMEDIKASI ANALGETIKA ANAK DI KOTA DENPASAR Dwidjayanti, Ni Kadek Candra; Suryaningsih, Ni Putu Aryati; Bakta, I Made
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 4 No. 3 (2023)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jcm.v4i3.1697

Abstract

Self-medication is an action taken by society in self-medicating. Knowledge of good medicine is needed in order to determine the appropriate treatment for self-medication. Research on self-medication behavior in the community found that most have good behavior.: This study aims to determine the level of knowledge, and behavior in children's analgetic self-medication. The research design used is quantitative descriptive with a cross-sectional research design. The number of samples used was 100 respondents with probability sampling. Measurements were made using questionnaires with Univariate and Bivariate Test analysis techniques. Percentage of parents' knowledge level in the medium category 40 (40%), parental behavior in the positive category 59 (59%). There was a significant relationship between the level of knowledge and behavior of parents and the p value (0.001). from research on the significant relationship between knowledge and behavior in analgetic self-medication in parents of children in Denpasar City. The need for counseling is more related to children's analgetic self-medication.
The Ergonomic Elderly Gym Improving Physical Fitness and Increasing The Bone Mass of The Elderly Ariati, N.N.; Adiputra, N.; Tirtayasa, K.; Adiatmika, I.P.G.; Pangkahila, A.; Sutjana, I.D.P; Bakta, I.M.; Manuaba, I.B.P; Sutajaya, I.M.
International Journal of Industrial Engineering and Engineering Management Vol. 1 No. 2 (2019)
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/ijieem.v1i2.2998

Abstract

The public is increasingly aware of the importance of exercise for the elderly because exercise is an option to reduce complaints due to setbacks and improve the health of the elderly. In fact the implementation in the field is often wrong as in Banjar Benaya which implements routine exercises only once a week with a duration less than 30 minutes, does not pay attention to nutritional needs, does not use sports clothing, and displays that are not clear. The measurement of elderly physical fitness is still relatively low. Based on these problems, improvements were made to the application of ergonomic elderly gymnastics due to improve elderly’s physical fitness and increase the bone mass.  This study used a treatment by subject design conducted in April 2017-August 2018. The target population was all elderly in Denpasar and the affordable population was determined by multistage random sampling then selected Banjaya Benaya Peguyangan Village with a sample of 20 people who met the inclusion criteria. The data collection were physical fitness and bone mass. The difference in treatment effects were analyzed using a Paired Sample t-Test with α = 0.05 for data with normal distribution and Wilcoxon test, α = 0.05 for data with abnormal distribution. Data showed that there were differences in physical fitness improvement in Period I and Period II after 8 weeks of gymnastics at 43.43% with very bad categories being bad, the difference in increase in whole body bone mass was 16.76% and leg bone mass 68.67%. Analysis of Paired Sample-t-Test physical fitness data and Wilcoxon test for bone mass data in Period I and Period II after gymnastics for 8 weeks, found that there was a significant difference (p <0.05). It can be concluded that ergonomic elderly gym can significantly improve physical fitness and increase bone mass of the elderly. It is recommended that the elderly continue to exercise with a duration of 30-45 minutes, the frequency of 3 times a week to maintain elderly’s physical fitness.
Hemophilia A yang Didapat: Suatu Tinjauan tentang Diagnosis dan Manajemen I Made Bakta
WMJ (Warmadewa Medical Journal) Vol 2 No 2 (2017): November 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.2.230.44-51

Abstract

Hemophilia A yang didapat atau acquired hemophilia A (AHA) adalah penyakit perdarahan yang didapat (acquired), suatu penyakit yang jarang,  penyakit autoimun yang ditandai oleh autoantibodi terhadap faktor VIII. Yang khas, penderita tidak menunjukkan riwayat perdarahan sebelumnya, datang dengan keluhan utama perdarahan spontan, terutama perdarahan kulit atau mukosa. AHA lebih banyak terjadi pada umur tua, baik pada laki maupun wanita dan dihubungkan dengan berbagai penyakit, seperti penyakit autoimun (lupus erithematosus sistemik, penyakit limfoproliferatif, artritis rematoid), keganasan atau kehamilan.  Sekitar setengah dari penderita bersifat idiopatik. AHA didiagnosis jika dijumpai penderita tanpa riwayat perdarahan sebelumnya, baik personal atau keluarga, dimana pemanjangan aPTT (activated plasma thromboplastin time) tidak dapat dikoreksi setelah pencampuran dengan sejumlah volume yang sama dari plasma penderita dan plasma normal yang diinkubasi selama 2 – 4 jam pada suhu 37oC. Kadar FVIII:C menurun.  Aktivitas titer inhibitor  FVIII:C yang spesifik dapat dideteksi dan diukur dengan Bethesda assay atau dengan modifikasinya Nijmegen assay. Dalam pengelolaan AHA, pengendalian terhadap perdarahan merupakan prioritas pertama. Pada penderita dengan kadar inhibitor yang rendah, desmopressin dapat digunakan. Tetapi FVIII by passing agents (activated prothrombin complex concentrate atau recombinant FVIIa) diperlukan pada penderita dengan kadar inhibitor yang tinggi atau penderita dengan episode perdarahan yang berat. Secara bersamaan dilakukan eradikasi terhadap inhibitor (autoantibodi) untuk mengurangi risiko perdarahan berikutnya. Dianjurkan terapi lini pertama dengan kortikosteroid atau terapi kombinasi kortikosteroid dengan siklofosfamid. Untuk terapi lini kedua dapat dipakai rituximab, jika terapi lini pertama gagal atau terdapat kontraindikasi.Kata kunci: hemophilia yang didapat, diagnosis, manajemen. (Acquired Hemophilia A: An Overview on Diagnosis and Management)Acquired hemophilia A (AHA) is a rare acquired bleeding disorder, an autoimmune disease characterized by autoantibody directed against factor VIII. Typically, patients with no prior history ofbleeding disorder, present with spontaneous bleeding, especially skin and mucosal bleeding. AHA occurs more frequently in the elderly, both in male and female and may be associated  with several conditions, such as autoimmune diseases (systemic lupus erythematosus, lymphoproliferative disease, rheumatoid arthritis), malignancies and pregnancy.  Around half of the patients are idiopathic. AHA is diagnosed in patients without previous personal or family bleeding history in which prolonged activated partial thromboplastin time  is not corrected after mixing and incubating for 2 – 4 hours at 37oC equal volumes of patient and normal plasma.  FVIII:C levels are reduced  and a specific FVIII inhibiting activity is detected and measured by the Bethesda  assay or its Nijmegen modification. In the management of AHA, control of acute bleeding is the first priority. In patients with low level inhibitor, desmopressin may be used. But FVIII by passing agents (activated prothrombin complex concentrate and recombinant activated FVII) are required for patients with high titre of antibody or with serious bleeding episode. Immediate autoantibody eradication to reduce subsequent bleeding risk should be performed. It is recommended initial treatment with corticosteroid or combination therapy with corticosteroid and cyclophosphamide and suggest second-line  therapy with rituximab if first-line therapy is fails or is contraindicated. Keywords: acquired hemophilia A, diagnosis, management.
Exploring Meditation Influence on Stem Cell: A Review of Current Evidence Santosa, I Gusti Ngurah Putra Eka; Jawi, I Made; Bakta, I Made; Yasa, I Wayan Putu Sutirta; Wirawan, I Made Ady; Lesmana, Cokorda Agung Bagus Jaya; Kandarini, Yenny; Purnamawati, Susy
Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA) Vol. 7 (2024): PROSIDING SINTESA
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/snts.v7i.3716

Abstract

Endogenous stem cells play a critical role in maintaining tissue homeostasis, repair, and regeneration. The interconnectedness of mind and body has long been recognized as influencing physical health, with practices such as yoga and meditation demonstrating positive effects on overall well-being. This review aims to synthesize current evidence on the effects of meditation on stem cell function, focusing on both indirect (telomere-related) and direct pathways. Meditation appears to influence stem cell function through various mechanisms. Indirectly, meditation may impact stem cells by modulating telomere length and activity. This modulation is likely mediated through stress reduction, modulation of the hypothalamic-pituitary-adrenal (HPA) axis, melatonin elevation, immune system modulation, and reduction of oxidative stress. Directly, meditation may influence stem cell trafficking and differentiation. While studies suggest potential benefits of meditation on stem cell function, further research is needed to fully elucidate the underlying mechanisms. Emerging evidence suggests that meditation may positively influence stem cell function through both indirect and direct pathways. Future research should focus on clarifying the precise mechanisms, investigating the role of meditation parameters, and conducting clinical trials to assess the therapeutic potential of meditation in promoting stem cell-mediated tissue regeneration and repair. A multidisciplinary approach involving researchers from various fields is crucial for comprehensively understanding the complex interplay between meditation, stem cells, and overall health.
EVALUATION OF THE ACCURACY OF USING TOPICAL ANTIBIOTICS IN SELF-MEDICATION FOR ACNE VULGARIS AT THE DENPASAR REGIONAL PHARMACY Alma Lystia Savitri Mahayasa; Ida Ayu Manik Partha Suthema; I Made Bakta
Journal Pharmaceutical Science and Application Vol. 5 No. 1 (2023): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2023.v05.i01.p01

Abstract

Background: One of the skin problems that are often experienced by teenagers today is acne. Acne vulgaris or acne is a chronic inflammatory disease of pilosebaceous follicles which is characterized by the formation of papules, pustules, or nodules. Objective: This study aims to provide an accurate description of the use of topical antibiotics in acne vulgaris patients and to find out which drugs are often used as self-medication for acne vulgaris. Methods: This research is included in a descriptive research design. Data collection was done by direct observation and recorded on the checklist sheet for Acne Vulgaris patients who did selfmedication at the pharmacy. Results: Judging from the evaluation of the accuracy of the use of topical antibiotics in AV patients at the Denpasar Regional Pharmacy, the results obtained were 53 patients, or 92.98% of patients included in the right indication group, 57 patients, or 100%, included in the right dose group, 54 patients or 94.74% included in the right group for the duration of administration, 57 patients or 100% were included in the appropriate time interval group for administration and 100% of patients were included in the side effect alert group. The accuracy of giving antibiotics, which is included in the category of inappropriate indications by 5.71% of respondents, and inappropriate duration of administration by 5.08% of respondents. The drugs used for AV therapy are Topical Retinoids, Mediklin Gel, Mediklin TR, and Erymed. The drug most often given by pharmacists is topical antibiotics, namely Mediklin TR from the Semisynthetic Lincosamide group, as much as 38.57%. Conclusion: There is still suitability for prescribing topical antibiotics in acne vulgaris seen from its severity. Keywords: Acne; Evaluation; Topical antibiotics
Co-Authors - Murtiananingsih, - - Saimi, - A. A. Mas-Putrawati AAG Sudewa D. Adi Purwa Hita, I Putu Gede Alma Lystia Savitri Mahayasa Alma Lystia Savitri Mahayasa Ambrosius Purba Anak Agung Ngurah Jaya Kusuma Anisa Hanum Anwar Santosa Ariati, N.N. Arundina Sanyoto Astawa N. M., Astawa N. Astawa P., Astawa Brad Otto Budha K. Claire Ryan Daniel Womsiwor Dewa Nyoman Wirawan Dewa Nyoman Wirawan, Dewa Nyoman Dharmayuda, Tjokorda Gede Dhiancinantyan Windydaca Brata Putri Djoko Roeshadi Duarsa, Dyah Paramita Dwidjayanti, Ni Kadek Candra Dyah Kanya Wati Dyah Pradnya P.D., Dyah Pradnya Dyah Pradnya Paramitha Duarsa Dyah Pradnya Paramitha Duarsa, Dyah Pradnya Paramitha Dyah Pradnyaparamita D, Dyah Pradnyaparamita Ekaputra Ekaputra, Ekaputra Gusti Putu Surya H. S. Habiba Muhiddin, H. S. Habiba Hari Bagianto I Dewa Made Sukrama I Dewa Nyoman Wirawan I Dewa Putu Sutjana I Ketut Agus Somia I Ketut Suastika I Ketut Suyasa I Made Ady Wirawan I Made Damriyasa I Made Duwi Sumohadi I Made Jawi I Made Jawi I Made Sudarmaja I Made Susila Utama I N Agus Bagiada I NYOMAN ADI SURATMA I Nyoman Arhya I Nyoman Budi Hartawan I Nyoman Mangku Karmaya I NYOMAN MANTIK ASTAWA I Nyoman Sutarsa I P G. Adiatmika I Putu Budi Wibawa I Putu Suiraoka I Putu Wantera I Wayan Losen Adnyan I Wayan Losen Adnyana I Wayan Putu Sutirta Yasa I Wayan Suranadi I Wayan Wita Ida Ayu Manik Partha Suthema Ida Bagus Gede Suparyatha Ida Bagus Komang Ardana Ida Bagus Putra Manuaba Ida Bagus Subanada IN Agus Bagiada IN Bagiada INT Suryadhi INT Suryadhi J. A. Pangkahila Karjono M, Karjono Ketut Siki Kawiyana Ketut Suata Ketut Suega Ketut Suega Ketut Suryana Ketut Tuti Parwati Merati Lesmana, Cokorda Agung Bagus Jaya Levi Anatolia Losen Adnyan Ludirdja, Evan Pratama LUH MERTASARI . Luh Seri Ani Made Jawi Made Krisna Adi Jaya Made Wiryana Manuaba, I.B.P Mirandinha Fortuna Sarmento Madeira, Angie N Adiputra N. Adiputra N. K. Niti Susila, N. K. Ni Made Andrinia Ratih Sri Indarswari Ni Nyoman Yunita Kusuma Bakta Ni Putu Aryati Suryaningsih Nita Fitria P. Astawa Purnamawati, Susy R. A.T. Kuswardhani Rena, Ni Made Renny A Rena, Ni Made Renny Anggreni Renny A Rena Rudi Wisaksana Santosa, I Gusti Ngurah Putra Eka Satoto D., Satoto Sawitri, Anak Agung Sagung Shannon Turnbul Sri Maliawan Sumohadi, I Made Duwi Suryadi N. T., Suryadi N. Sutajaya, I.M. Sutema, Ida Ayu Manik Partha Tirtayasa, K. Tjok Darmayuda Tjok Gde Darmayuda Tjokorda Gde Agung Senapathi Tjokorda Gde Bagus Mahadewa Tjokorda Gde Dharmayuda Tjokorda Gde Dharmayuda Tuti Parwati Merati W. A., W. Winarto, Daniel Wiryana M., Wiryana Wulansari Manuaba, Ida Ayu Ratih Xavier Leverve Yenny Kandarini