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Metabolisme Energi pada Cedera Otak Traumatik Suarjaya, I Putu Pramana; Bisri, Tatang; Wargahadibrata, A. Himendra
Jurnal Neuroanestesi Indonesia Vol 1, No 4 (2012)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (282.87 KB) | DOI: 10.24244/jni.vol1i4.195

Abstract

Cedera otak traumatik mengakibatkan terjadinya kaskade gangguan fisiologi dan biokimia yang berpengaruh pada metabolisme dan produksi energi serebral. Setelah cedera otak traumatik, terjadi perubahan berkelanjutan pada metabolisme energi serebral yang ditandai oleh terjadinya disfungsi mitokondria dan meningkatnya glikolisis. Cedera otak traumatik juga mengakibatkan adanya peningkatan kebutuhan energi karena terjadinya gangguan hemostasis ion, gangguan hantaran glutaminergik dan proses perbaikan jaringan yang membutuhkan energi. Kombinasi dari dari pelepasan ATP dari sinap preterminal, disfungsi mitokondria, penurunan aliran darah otak setelah cedera dan peningkatan kebutuhan energi otak pada saat cedera akan menimbulkan ketidak seimbangan antara penyediaan dan kebutuhan energi pada cedera otak traumatik.Energy Metabolism in Traumatic Brain InjuryDuring Traumatic brain injury, secondary insults will led to physiological and biochemical cascade that disturbing cerebral energy metabolism. After traumatic brain injury, sustained changes in cellular energy metabolism have been described as accelerated glycolysis or mitochondrial dysfunction.Traumatic brain injury is associated with increasing energy needs to restore cerebral ionic hemostasis, distubance in glutaminergic process and tissue repairing. Combination of ATP release from pre-terminal synaps, mitochondrial dysfunction, decrease brain oxygen delivery and increasing energy metabolic needs results in cerebral energy imbalances.
Anesthesia Management of Patients with Redo Craniotomy: Cases of Supratentorial Recidive Tumors Bisri, Dewi Yulianti; Septiani, Gusti Ayu Pitria; Limawan, Michaela Arshanty; Bisri, Tatang
Interdisciplinary Social Studies Vol. 2 No. 8 (2023): Special Issue
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/iss.v2i8.450

Abstract

Background: Compared to non-surgical therapies, redo craniotomy is linked to improved neurological state and a lower mortality rate. But it also carries a higher price tag and complication risk. Aim: The researchers would like to discover anesthesia management of patients with redo craniotomy in patients with supratentorial recidive tumors. Method: The researchers used the case study method. Two cases of redo craniotomy performed at the Santosa Hospital Bandung Central Indonesia are presented. The first case involved a 24-year-old male with a supraorbital tumor, GCS 15, and the second case involved a 43-year-old woman with  meningiomas, GCS 15. The first patient underwent redo craniotomy six (6) months after the first operation, while the second patient underwent the procedure three (3) months after the first operation. These patients were subjected to anesthesia using the same techniques and anesthetic drugs. patients were positioned in a neutral position with 20-30 degree head up, voluntary hyperventilated, and adequate anxiolytics. Findings: The bleeding volume of the patients was 800 mL for the first patient and 1,000 mL for the second, and the fluid balance was maintained using the ringerfundin balance solution. The durations of the operation of the first and second patients were  4 and 6.5 hours, respectively. Postoperatively, patients were treated in the ICU for one day under mechanical ventilation and were transferred to the ward after extubation. Better intraoperative care, improved surgical skills, surgical equipment, and better intensive care support are likely to improve outcomes in patients with redo craniotomy.
The Comparison between Spinal Anesthesia Bupivacaine and Sevoflurane Anesthesia for Cesarean Section on Apgar Score Bisri, Tatang; Noer Rochmah, Elly; Kurniawan, Arief; Stella, Angela
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

The use of the anesthetic technique for cesarean section is still debatable because of the side effects caused by anesthesia for mothers and neonates. The succeed to determine anesthetic technique can be seen from the outcome of the final condition of the mother and the neonates. The assessment of the succeed to determine anesthetic technique in neonates has been using the Apgar score by assessing the clinical status of the newborn in the first and fifth minutes. This research is aimed to understand the comparison between Apgar scores in cesarean section using general anesthesia sevoflurane and spinal anesthesia bupivacaine. This research is analytical retrospective with a cross-sectional study approach, using a total sample of 40 patients who performed cesarean section from August to November 2021, the samples were taken by consecutive sampling. The data was taken from the medical records of the Melinda Mother and Child Hospital, Bandung. The results of this research showed that there was no significant difference in the APGAR Score first minute between general anesthesia and spinal anesthesia (p=0,054) in the fifth minute (p=0,708). There was no effect on APGAR scores in the general anesthesia sevoflurane group and spinal anesthesia bupivacaine group, and both anesthetic groups had a good effect on neonates DOI : 10.35990/amhs.v1n3.p128-136 REFERENCES Prawirohardjo S. Ilmu Bedah Kebidanan. In: Wiknjosastro, Hanifa, editors. Edisi 1. Jakarta: Yayasan Bina Pustaka Sarwono Prawirohardjo; 2007. p. 133. Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. Hasil Rikesdas 2013. Jakarta: Kementerian Kesehatan RI; 2013. p. 174. BKKBN, BPS, Kementerian Kesehatan RI. Survei Demografi dan Kesehatan Indonesia 2017 Provinsi DKI Jakarta. 2012. Available from: http://demografi.bps.go.id/phpfiletree/sdki/BahanAjarSDKI2007/Lainnya/PublikasiSDKI02-03/RingkasanSDKI02-03.pdf Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s Clinical Anesthesiology. 5th ed. New York: McGraw-Hill Education; 2013. Tawfik MM, Tolba MA. Chestnut’s Obstetric Anesthesia: Principles and Practice. Anesth Analg. 2019;129(5):e170. Tsen LC, Bateman BT. Anesthesia for Cesarean Delivery. In: Chestnut DH, Wong C, editors. Chestnut’s Obstetric Anesthesia: Principles and Practice. 6th ed. Philadelphia: Elsevier; 2020. Datta S, Kodali BS, Segal S. Obstetric Anesthesia Handbook. 5th ed. New York: Springer; 2010. Katzung BG, Masters SB, Trevor AJ. Farmakologi Dasar dan Klinik. 12th ed. New York: McGraw-Hill Companies, Inc; 2010. Prawirohardjo S. Ilmu Kebidanan Sarwono. 4th ed. Jakarta: PT Bina Pustaka Sarwono Prawirohardjo; 2010. p. 678–81. Wilson DDMJ. Spinal anaesthesia for caesarean section. J Soc Obs Gynaecol Can. 1998;20(8). Neal JM, Rathmell JP. Complications in Regional Anesthesia and Pain Management. 2nd ed. Philadelphia: Lippincott Williams & Wilkins, a Wolters Kluwer business; 2007. Chumpathong S, Chinachoti T, Visalyaputra S, Himmunngan T. Incidence and risk factors of hypotension during spinal anesthesia for cesarean section at Siriraj Hospital. J Med Assoc Thail. 2006;89(8):1127–32. Hadzic A. Hadzic’s Textbook of Regional Anesthesia and Acute Pain Management. 2nd ed. New York: McGraw-Hill Education; 2017. Watterberg KL, Aucott S, Benitz WE, et al. The Apgar Score. Pediatrics. 2015;136(4):819–22. Thavarajah H, Flatley C, Kumar S. The relationship between the five-minute Apgar score, mode of birth, and neonatal outcomes. J Matern Fetal Neonatal Med. 2018;31(10):1335–41. Rumahorbo FT. Perbandingan Nilai Apgar Neonatus pada Seksio Sesar antara Anestesia Umum dan Anestesia Spinal. e-CliniC. 2014;2(2). Christiana M, Bisri T. Perbandingan antara Anestesi Umum dengan Anestesi Spinal untuk Seksio Sesarea terhadap Skor Apgar. Anesthesia dan Critical Care. 2015;(10):99–106. Septivani A, Tanuwidjaja S, Santosa D. Perbandingan skor Apgar bayi yang lahir melalui seksio sesarea terhadap penggunaan anestesi umum dan anestesi lokal di RSUD Al-Ihsan. Prosiding Pendidikan Dokter Universitas Islam Bandung. 2018;519:673–82. Flora L, Redjeki IS, Wargahadibrata AH. Perbandingan efek anestesi spinal dengan anestesi umum terhadap kejadian hipotensi dan nilai Apgar bayi pada seksio sesarea. J Anestesi Perioper. 2014;2(2):105–16. Karaman S, Akercan F, Aldemir O, et al. The maternal and neonatal effects of the volatile anaesthetic agents desflurane and sevoflurane in caesarean section: a prospective, randomized clinical study. J Int Med Res. 2006;34.
Co-Authors , Rizki , Suwarman - Irwan, - A. Himendra Wargahadibrata A. Muthalib Nawawi Agus Junaidi Aini, Quratul Akbar, Ieva B Alifahna, Muhammad Rezanda Andie Muhari Barzah, Andie Muhari Ardi Zulfariansyah Arief Kurniawan Bambang Suryono, Bambang Christanto, Sandhi Christanto, Sandhi christiana, monica Dedi Fitri Yadi Dewi Yulianti Bisri Diana C. Lalenoh, Diana C. Diana Lalenoh Erias, Muhammad Erwin Pradian Ezra Oktaliansah Firdaus, Riyadh Firdaus, Riyadh Fithrah, Bona Akhmad Fithrah, Bona Akhmad Fitri Sepviyanti Sumardi Giovanni, Cindy Giovanni, Cindy Hamzah, Hanzah Hermawanto, Agung Hindun Saadah, Hindun Ida Bagus Krisna Jaya Sutawan Ieva B. Akbar Ike Sri Redjeki Indrayani, Ratih Rizki Iwan Abdul Rachman Iwan Fuadi Jasa, Zafrullah Khany Kusuma Harimin, Kusuma Laksono, Buyung Hartiyo Lalenoh, Diana Christine Lalenoh, Diana Christine Limawan, Michaela Arshanty M. Dwi Satriyanto M. Erias Erlangga, M. Erias M. Sofyan Harahap Mariko Gunadi Martinus, Fardian Martinus, Fardian MM Rudi Prihatno, MM Rudi Muh. Rumli Ahmad Muhamad Adli Boesoirie, Muhamad Adli Muhammad Habibi Ningsih, Diana Fitria Ningsih, Diana Fitria Noer Rochmah, Elly Nugraha, Ade Aria Nugraha, Ade Aria Nuryanda, Dian Oetoro, Bambang J. Oetoro, Bambang J. Okatria, Ahmado Pontjosudargo, Fransiska Ambarukmi Priyadi, Hendri Putri, Andika C. Putu Pramana Suarjaya Radian Ahmad Halimi Rahmadsyah, Teuku Rahordjo, Sri Rasman, Marsudi Rasman, Marsudi Reza Widianto Sudjud Rose Mafiana Rovina Ruslami, Rovina Ruby Satria Nugraha Ruli Herman Sitanggang Saleh, Siti Chasnak Saleh, Siti Chasnak Saputra, Tengku Addi Saputra, Tengku Addi SATRIYAS ILYAS Septiani, Gusti Ayu Pitria Soefviana, Stefi Berlian Sri Rahardjo Stella, Angela Subekti, Bambang Eko Subekti, Bambang Eko Suryaningrat, IGB Susanto, Bahtiar Sutanto, Sigit Sutanto, Sigit Suwarman Suwarman, Suwarman Suwarman, S Suwarman, S Syafruddin Gaus Thayeb, Srilina Theresia C. Sipahutar Theresia Monica Rahardjo Uhud, Akhyar Nur Widiastuti, Monika - Wirawijaya, Dear Mohtar Wirawijaya, Dear Mohtar Wirawijaya Wullur, Caroline Wullur, Caroline Yunita Susanto Putri Zaka Anwary, Army