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Journal : Indonesian Physical Review

EFFECT OF NIGELLA SATIVA EXTRACTS IN LIVER CELL OF RATTUS NORVEGICUS INDUCED BY PIROXICAM Kurniasari, Septiana
Indonesian Physical Review Vol. 4 No. 3 (2021)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ipr.v4i3.95

Abstract

Piroxicam has the potential to cause side effects, especially in the liver, so that it can causes cell damage and impair the function and work of the liver organs. One way to minimize liver cell damage is by giving black cumin (Nigella sativa). This study aims to analyze the effect of black cumin (Nigella sativa) extract on the level of liver cell damage in rats (Rattus norvegicus) induced by Piroxicam. This study used 80 male rats and divided into 3 groups, namely negative control (K-), Piroxicam non-extract (P-) and Piroxicam plus extract (P +). Black cumin extract is given orally at a dose of 2 gr/kgBW; 3 gr/kgBW; 4 gr/kgBW; 5 gr/kgBW and 6 gr/kgBW, while the Piroxicam dosage given is 1 g/kgBW and 3 g/kgBW. The liver cell damage was done by observing the microscopic image. The results showed that the more doses of Piroxicam were given, the higher the level of cell damage. Along with increasing the dose of black cumin extract, the cell damage is reduced.
THE MEASUREMENT OF ENVIRONMENTAL RADIATION EXPOSURE AROUND THE LINAC RADIOTHERAPY BUNKER Kurniasari, Septiana; Hentihu, Fatimah K; Anto, Alfian K; Prasetyo, Henry
Indonesian Physical Review Vol. 5 No. 1 (2022)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ipr.v5i1.129

Abstract

Radiotherapy is cancer therapy using radiation. One of the tools used for radiotherapy is the Linac. Using Linac also can have a detrimental effect on radiation workers, patients, and the public. The reaction can cause activation around the room to become radioactive. Therefore, radiation protection is needed. This research aimed to measure environmental radiation exposure as a radiation protection effort around the Linac bunker. This research uses a quantitative method by collecting data directly on the area around the Linac bunker, with a distance of ± 30 cm from the bunker wall, using the STEP OD-02 Detector. The average Linac operation is 2000 hours/year, while the safe dose limit used is 1/2 dose Limit from Nuclear Power Monitoring Agency. Based on measurements of environmental radiation exposure, there are eight areas classified as safe and four other regions experiencing radiation leakage, including Doors with a radiation exposure difference of 0.078 Sv/hour; West Field (0.074 Sv/hour); TPS Room (0.302 Sv/hour); and Meeting Rooms (0.199 Sv/hour), but still within the safe limit of radiation dose. The environmental radiation exposure around the Linac Radiotherapy bunker is safe.
THE EFFECT OF HANDPHONE RADIATION ON HEMATOLOGY PROFILES Kurniasari, Septiana; Yunus, Muhammad; Madjid, Nursia; Umar, Sartika Rusdin; Amir, Asmiati; Fuadi, Nurul
Indonesian Physical Review Vol. 6 No. 2 (2023)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ipr.v6i2.233

Abstract

The use of handphone is increasing, making handphone users have to focus more on the side effects of using handphone on health. Handphone is included in the category of electromagnetic waves. Exposure to electromagnetic fields can affect human health, especially the hematological profile. This type of research is observational research with a descriptive approach. Hemoglobin, erythrocyte, leukocyte and thrombocyte levels were obtained from the results of blood checks in the laboratory. The results showed that exposure to handphone radiation caused a decrease in hemoglobin levels up to 11%, an increase in erythrocyte levels up to 13%, an increase in leukocyte levels up to 14%, and an increase in thrombocyte levels up to 35%.Handphone radiation triggersoxidative stress caused by formation of ROS (Reactive Oxygen Species).