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THE EFFECTS OF AGE ON BIOCHEMISTRY PROFILES OF ACEH CATTLE BLOOD Khairita, Lia; Esfandiari, Anita; Widhyari, Sus Derthi; Winarsih, Wiwin
Jurnal Kedokteran Hewan Vol 15, No 3 (2021): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v15i3.21698

Abstract

The purpose of this study was to analyze the effects of age on the biochemistry profiles of aceh cattle, which included examinations of: total protein (TP), albumin, globulin, albumin/globulin ratio (A/G), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), creatine kinase (CK), blood urea nitrogen (BUN), calcium (Ca), phosphorus (P) and magnesium (Mg) . Sixteen clinically healthy aceh cattle aged 2-4 years old, and 16 aceh cattle aged 4-6 years old were purposively selected for the study. Blood samples were drawn from the jugular vein and subjected to blood biochemistry measurements using commercial kits. The results showed that serum concentrations of TP, globulin, AST and Ca of aceh cattle were significantly (P0.05) higher in age group 4-6 years old, while ALP activity was significantly (P0.05) higher in age group 2-4 years old. In conclusion, age must be considered as a factor when interpreting the blood biochemistry profiles of aceh cattle.
Histopatologi Hati Mencit (Mus Musculus) yang Diberikan Minuman Ringan Berkarbonasi dan Ekstrak Daun Kersen (Muntingia Calabura L.): Liver Histopathology of Mice (Mus Musculus) Induced by Carbonated Soft Drink and Kersen Leaves Extract (Muntingia Calabura L.) Azhim Ash Siddiq, Muhammad Nuzul; Majiding, Chaidir Masyhuri; Rozi, Fahrul; Winarsih, Wiwin
Jurnal Sains dan Kesehatan Vol. 6 No. 2 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i2.1886

Abstract

High consumption of carbonated soft drinks (CSD) has caused risks of metabolic syndrome, obesity, various chronic diseases, and organ damage. Kersen has the potential to prevent and reduce damage to the liver caused by CSD. The study aimed to analyze the liver histopathological of mice given CSD and the effect of Kersen leaf extract. This experimental study used a completely randomized design with 25 male white mice divided into 5 groups, namely control grup (K), negative control (N), treatment 1, 2, and 3 with doses (35 mg/30g BW, 45 mg/30g BW, 65 mg/30g BB) for 30 days. The sample was terminated on the 31st day, and the liver organs were prepared to observe the microscopic of the liver. The analytical test used the ANOVA test with Duncan's multiple-range test. The results showed that the negative control group had significantly lower numbers of liver cell damage than the positive controls who were given CSD (p<0.05), and the treatment groups 2 and 3 also had significantly less cell damage than the positive control group and did not significantly different from the negative control group. Kersen leaf extract can prevent and reduce liver cell damage in carbonated soft drink-induced mice.   Keywords:          Liver, Histopathology, Kersen, Mice, Soft drink   Abstrak Konsumsi minuman berkarbonasi/ carbonated soft drink (CSD) yang berlebih berisiko menyebabkan terjadinya sindrom metabolik, obesitas, berbagai penyakit kronis, dan kerusakan organ. Kersen berpotensi mencegah dan mengurangi kerusakan pada hati yang disebabkan oleh CSD. Penelitian ini bertujuan untuk melihat gambaran histopatologi hati mencit yang diberikan minuman CSD dan efek pemberian ekstrak daun kersen. Penelitian experimental ini menggunakan rancangan acak lengkap dengan 25 mencit putih jantan yang dibagi 5 kelompok yaitu kelompok kontrol (K), kontrol negatif (N), perlakuan 1, 2, dan 3 dengan dosis (35 mg/30g BB, 45 mg/30g BB, 65 mg/30g BB) selama 30 hari. Sampel diterminasi pada hari ke 31 dan organ hepar dibuat preparat untuk diamati gambaran mikroskopis hati. Uji analisis menggunakan uji beda ANOVA dengan uji lanjut Duncan’s multiple-range test. Hasil pengamatan menunjukkan bahwa kelompok kontrol negatif memiliki jumlah kerusakan sel hati yang signifikan lebih rendah dibandingkan dengan kontrol positif yang diberikan CSD (p<0.05) dan kelompok perlakuan 2 dan 3 juga signifikan memiliki jumlah kerusakan sel yang lebih sedikit dibandingkan kelompok kontrol positif serta tidak berbeda signifikan dengan kelompok kontrol negatif. Ekstrak daun kersen memberikan pengaruh terhadap pencegahan dan mengurangi kerusakan sel hati pada mencit putih yang diberikan CSD.   Kata Kunci:         Hepar, Histopatologi, Kersen, Mencit, Carbonated Soft Drink
Hubungan Komunikasi Terapeutik Dengan Tingkat Kecemasan Ibu Hamil Primigravida Winarsih, Wiwin; Wulandari, Setyo Retno
Madu : Jurnal Kesehatan Vol 13, No 1 (2024): Juni 2024
Publisher : Program Studi DIV Kebidanan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31314/mjk.13.1.18-23.2024

Abstract

Anxiety during pregnancy up to the third trimester affects the birth process, child development, premature birth, low birth weight (LBW), prolonged labor, mental and motor disorders of the child, and even maternal death. In providing midwifery care, one of the competencies that midwives must have been the ability to communicate in midwifery services. Communication skills will underlie efforts to solve client problems, making it easier to provide assistance to clients, both medical services and psychological services are provided with a therapeutic communication approach. Objective: to determine the relationship between therapeutic communication and the level of anxiety of primigravida pregnant women at the Banguntapan II Bantul Community Health Center. Method: This type of research is quantitative with descriptive correlation methods. This research uses a cross-sectional approach. The total population in January was 63 respondents. The sampling method uses a purposive sample technique. The number of samples obtained was 40 respondents. The instrument used is a questionnaire. Results: Based on the results of the Kendall Tau correlation test, a correlation coefficient of -0.329 was obtained with a p-value of 0.006, smaller than 0.05 (p<0.05), so the hypothesis in the research was accepted. Conclusion: there is a relationship between therapeutic communication and the level of anxiety of primigravida pregnant women
Effects of Kersen leaves extract (Muntingia calabura L.) on SGOT and SGPT levels of soft drink induced mice Siddiq, Muhammad Nuzul Azhim Ash; Marliyati, Sri Anna; Riyadi, Hadi; Winarsih, Wiwin
Jurnal Gizi dan Pangan Vol. 14 No. 2 (2019)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (297.858 KB) | DOI: 10.25182/jgp.2019.14.2.69-76

Abstract

This study aimed to analyse the antioxidant activity, total phenols, and flavonoids of kersen leaves (Muntingia calabura L.) extract (KLE) and determine the hepatoprotective activity of KLE in soft drink induced mice. Soft drinks induction causes liver injuries which increases the serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) levels. Mice were divided into five treatment groups (n=5) and were given Tween 80 (1%) (normal control), Tween 80 (1%) and 7 ml soft drinks (negative control), KLE (1000, 1500, and 2000 mg/kg), and 7 ml soft drinks per oral once daily for 4 weeks. Antioxidant activity was measured by 2.2-diphenyl-1-picrylhydrazyl (DPPH) method. Total phenols and flavonoids were analyzed by Folin-ciocalteu colorimetric and aluminium chloride (AlCl3) method. The blood samples were collected for biochemical analysis. The result showed that the KLE antioxidant activity were 11.11+0.50 ppm. Total phenols and flavonoids detected in the KLE samples were 2.19+0.12 mgGAE/g and 2.43+0.24 mgQE/g respectively. Mice treated with KLE had a significantly lower (p<0.05) serum SGOT and SGPT levels than negative control group. In conclusion, KLE has a potential hepatoprotective activity that works in synergy with its antioxidant activity.
Pengaruh Budaya Kerja dan Iklim Kerja Terhadap Kinerja Karyawan pada PT. Korin Technomic Cirebon Furqon, Muhammad; Wiwin Winarsih
ATRABIS Jurnal Administrasi Bisnis (e-Journal) Vol. 10 No. 1 (2024): ATRABIS: Jurnal Administrasi Bisnis (e-Journal)-Juni 2024
Publisher : Program Studi Administrasi Bisnis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38204/atrabis.v10i1.1957

Abstract

Abstrak: Penelitian ini bertujuan untuk menilai pengaruh budaya kerja dan iklim kerja terhadap kinerja karyawan di PT Korin Technomic Cirebon. Data dikumpulkan melalui penyebaran kuesioner kepada 74 karyawan di PT Korin Technomic. Data dianalisis menggunakan SPSS Statistic Versi 23. Metode pengumpulan data menggunakan kuesioner yang telah divalidasi dan direliabilitasi oleh pihak sesuai kriteria pada sampel yang diteliti. Metode analisis data mencakup analisis deskriptif, analisis korelasi, serta uji hipotesis regresi linear berganda. Hasil dari riset didapatkan, budaya kerja secara individu berdampak positif dan signifikan terhadap kinerja karyawan, begitu pula dengan iklim kerja. Secara keseluruhan, budaya kerja dan iklim kerja bersma-sama memberikan dampak positif dan signifikan terhadap kinerja karyawan. Keywords: budaya kerja, iklim kerja, kinerja karyawan Abstract: This study analyzes the effects of work culture and work climate on employee performance at PT Korin Technomic Cirebon. Data was collected through the distribution of questionnaires to 74 employees at PT Korin Technomic. The data were analyzed using SPSS Statistics Version 23. The method of data collection utilized validated and reliable questionnaires as per the criteria set by the relevant parties for the sample under study. Data analysis methods included descriptive analysis, correlation analysis, and multiple linear regression hypothesis testing. The research findings indicated that individual work culture had a positive and significant impact on employee performance, as did the work climate. Overall, both work culture and work climate together had a positive and significant impact on employee performance. Keywords: work culture, work climate, employee performance
Model Participatory Experiential Learning untuk Peningkatan Literasi Investasi Digital Aparatur Pemerintah Daerah Winarsih, Wiwin; Ekawarti, Yuni; Veronica, Aries; Alfiana, Yeni; Widyastuti, Sari Mustika; Yanti, Dwi
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 2 (2025): Desember
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Purpose: This community service program aimed to enhance digital investment literacy among employees of the South Sumatra Provincial Communication and Information Office (Diskominfo), particularly millennials and Gen Z, through the application of the Participatory Experiential Learning (PEL) Approach. Methodology/approach: Findings indicate an overall improvement in digital investment literacy. Significant progress was observed in differentiating between fixed-income and growth-oriented instruments mean score 3.95 to 4.17 and in evaluating portfolio performance from score 3.73 to 4.17. Moderate improvements were found in investment horizon and risk awareness, whereas slight decreases occurred in linking welfare with investment capacity and aligning risk profiles with financial goals. Results/findings: The findings indicated a significant improvement in participants’ knowledge and skills. The average post-test scores were notably higher than pre-test scores, demonstrating enhanced understanding of financial management and confidence in selecting appropriate digital investment instruments such as mutual funds, stocks, and digital-based financial products. Conclusions: The PEL approach effectively improved digital investment literacy among young government employees by combining experiential and participatory learning. Limitations: The study was limited to 33 participants from a single institution, with effectiveness measured only through pre- and post-tests, and without longitudinal evaluation. Contribution: This program contributes to strengthening digital financial literacy capacity among government employees and provides an experiential learning-based model that may be replicated in similar institutions and communities.
The Influence of Corporate Social Responsibility Disclosure, Dividend Policy, and Inflation on Stock Prices Mustika, Sari; Alfiana, Yeni; Winarsih, Wiwin; Veronica, Aries; Dwiyanti; Allehandro, Reza
Jurnal Ilmiah Ekonomi Global Masa Kini Vol. 16 No. 2 (2025): Vol. 16 No. 2
Publisher : Universitas Indo Global Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36982/jiegmk.v16i2.6100

Abstract

This study aims to determine the effect of CSR disclosure, dividend policy, and inflation on stock prices. The research design is causality research. The sample size was 40 companies in the food and beverage sector listed on the Indonesia Stock Exchange for the 2022-2024 period. The sampling technique used purposive sampling. The analysis technique used multiple linear regression. The analysis results found a CSR disclosure coefficient of 0.632, indicating no effect on stock prices. This indicates that the size of CSR does not directly impact stock prices. A company's CSR information is not a primary consideration for investors in making investment decisions. Furthermore, the analysis results show a Dividend Payout Ratio policy coefficient of 0.006, indicating an effect on stock prices. This indicates that the higher the dividends distributed to shareholders, the higher the company's stock price will be, as investors tend to value companies that provide stable and consistently increasing dividends. DPR is the percentage of a company's net profit paid to shareholders. This indicates a positive signal for the company's financial health. Furthermore, the inflation coefficient of 0.791 indicates that the inflation rate has no effect on stock prices. Continued inflation tends to cause stock prices to decline. This is caused by various factors, particularly a decline in public purchasing power. Simultaneously, all three independent variables influence stock prices. CSR disclosure, dividend policy, and inflation are economic factors that can influence stock prices. When these factors work together, their influence on stock prices can be more complex, but they can also create mutually supportive conditions for stock price increases. Keywords : Stock Price, CSR Disclosure, Dividend, Inflation