Claim Missing Document
Check
Articles

Found 34 Documents
Search

Histopatologi Hati Mencit (Mus Musculus) yang Diberikan Minuman Ringan Berkarbonasi dan Ekstrak Daun Kersen (Muntingia Calabura L.): Liver Histopathology of Mice (Mus Musculus) Induced by Carbonated Soft Drink and Kersen Leaves Extract (Muntingia Calabura L.) Muhammad Nuzul Azhim Ash Siddiq; Chaidir Masyhuri Majiding; Fahrul Rozi; Wiwin Winarsih
Jurnal Sains dan Kesehatan Vol. 6 No. 2 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i2.1886

Abstract

High consumption of carbonated soft drinks (CSD) has caused risks of metabolic syndrome, obesity, various chronic diseases, and organ damage. Kersen has the potential to prevent and reduce damage to the liver caused by CSD. The study aimed to analyze the liver histopathological of mice given CSD and the effect of Kersen leaf extract. This experimental study used a completely randomized design with 25 male white mice divided into 5 groups, namely control grup (K), negative control (N), treatment 1, 2, and 3 with doses (35 mg/30g BW, 45 mg/30g BW, 65 mg/30g BB) for 30 days. The sample was terminated on the 31st day, and the liver organs were prepared to observe the microscopic of the liver. The analytical test used the ANOVA test with Duncan's multiple-range test. The results showed that the negative control group had significantly lower numbers of liver cell damage than the positive controls who were given CSD (p<0.05), and the treatment groups 2 and 3 also had significantly less cell damage than the positive control group and did not significantly different from the negative control group. Kersen leaf extract can prevent and reduce liver cell damage in carbonated soft drink-induced mice.   Keywords:          Liver, Histopathology, Kersen, Mice, Soft drink   Abstrak Konsumsi minuman berkarbonasi/ carbonated soft drink (CSD) yang berlebih berisiko menyebabkan terjadinya sindrom metabolik, obesitas, berbagai penyakit kronis, dan kerusakan organ. Kersen berpotensi mencegah dan mengurangi kerusakan pada hati yang disebabkan oleh CSD. Penelitian ini bertujuan untuk melihat gambaran histopatologi hati mencit yang diberikan minuman CSD dan efek pemberian ekstrak daun kersen. Penelitian experimental ini menggunakan rancangan acak lengkap dengan 25 mencit putih jantan yang dibagi 5 kelompok yaitu kelompok kontrol (K), kontrol negatif (N), perlakuan 1, 2, dan 3 dengan dosis (35 mg/30g BB, 45 mg/30g BB, 65 mg/30g BB) selama 30 hari. Sampel diterminasi pada hari ke 31 dan organ hepar dibuat preparat untuk diamati gambaran mikroskopis hati. Uji analisis menggunakan uji beda ANOVA dengan uji lanjut Duncan’s multiple-range test. Hasil pengamatan menunjukkan bahwa kelompok kontrol negatif memiliki jumlah kerusakan sel hati yang signifikan lebih rendah dibandingkan dengan kontrol positif yang diberikan CSD (p<0.05) dan kelompok perlakuan 2 dan 3 juga signifikan memiliki jumlah kerusakan sel yang lebih sedikit dibandingkan kelompok kontrol positif serta tidak berbeda signifikan dengan kelompok kontrol negatif. Ekstrak daun kersen memberikan pengaruh terhadap pencegahan dan mengurangi kerusakan sel hati pada mencit putih yang diberikan CSD.   Kata Kunci:         Hepar, Histopatologi, Kersen, Mencit, Carbonated Soft Drink
Pengaruh Edukasi Kelas Ibu Hamil Terhadap Kemampuan Dalam Deteksi Dini Komplikasi Kehamilan Winarsih, Wiwin; Wulandari, Setyo Retno
Madu : Jurnal Kesehatan Vol 13, No 2 (2024): Desember 2024
Publisher : Program Studi DIV Kebidanan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31314/mjk.13.2.124-132.2024

Abstract

Every pregnancy has a risk of complications that can threaten the lives of the mother and baby. Risks that can occur in pregnancy include being too young to get pregnant, too old to get pregnant > 35 years, too close or far apart pregnancies and too many children or often known as 4 Too. One effort that can be made to prevent pregnancy complications in pregnant women is to increase the mother's knowledge about early detection of pregnancy complications through education in pregnancy classes. Through education in pregnancy classes, it is hoped that pregnant women can have the ability to detect complications early during pregnancy so that they can reduce maternal and fetal mortality rates. Objective of this study to determine the effect of education in pregnancy classes on the ability to detect early pregnancy complications. This study is a quantitative study with a pre-experimental design with a one group pretest and posttest design. The population in this study was 321 people. The sampling technique used was purposive sampling of 77 people. The results of statistical analysis using Wilcoxon test that had been carried out obtained a p value of 0.000, because the value of 0.000 <0.05, the hypothesis in the study was accepted. Conclusion: There is an influence of education for pregnant women's classes on the ability to detect early pregnancy complications in the Kalasan Health Center Work Area in 2024.
Apakah Audit Tenure, Audit Fee, Ukuran Perusahaan Akan Mempengaruhi Kualitas Audit Sektor Pertambangan di Bursa Efek Indonesia Veronica, Aries; Winarsih, Wiwin; Yanti, Dwi; Alfiana, Yeni
Jurnal Media Akuntansi (Mediasi) Vol. 7 No. 2 (2025): Jurnal Media Akuntansi (MEDIASI), Maret 2025
Publisher : Universitas PGRI Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/jmediasi.v7i2.18365

Abstract

ABSTRACT This study was conducted by the author to find out whether audit quality is influenced by audit tenure, audit fees, and company size in the mining sector on the Indonesia Stock Exchange. This study utilizes secondary data with a quantitative approach using a sampling technique, namely purposive sampling, which was obtained with a total of 41 issuers as the research sample.In the research, the results showed that audit quality was not influenced by audit tenure, with a significance value of 0.358. Meanwhile, audit fees have a significant influence on audit quality with a significance value of 0.007. Meanwhile, company size has no impact on audit quality, as shown by the significance value of 0.290. Keywords: Audit Tenure, Audit Fee, Company Size, Audit Quality. ABSTRAK Studi ini dilakukan penulis untuk mengetahui apakah kualitas audit dipengaruh oleh audit tenure, audit fee, dan ukuran perusahaan yang terdapat pada sektor pertambangan di Bursa Efek Indonesia. Studi ini memanfaatkan data sekunder dengan pendekatan kuantitatif dengan menggunakan teknik pengambilan sampel yaitu purposive sampling yang diperoleh dengan total 41 emiten sebagai sampel penelitian. Pada penelitian didapatkan hasil jika kualitas audit tidak dipengaruhi oleh audit tenure, dengan nilai signifikansi sebesar 0,358. Sedangkan, audit fee memiliki pengaruh signifikan terhadap kualitas audit dengan nilai signifikansi 0,007. Sementara itu, untuk ukuran perusahaan tidak memberikan dampak pada kualitas audit, sebagaimana ditunjukkan oleh nilai signifikansi 0,290. Kata kunci: Audit Tenure, Audit Fee, Ukuran Perusahaan, Kualitas Audit.
Analysis of Nursing Care to mother with Post-Caesarean Pain and Lavender Aromatherapy Intervention Winarsih, Wiwin; Yekti Widadi, Sri
Nursing Case Insight Journal Vol. 2 No. 3 (2024): Nursing Case Insight Journal
Publisher : CV. Literasi Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63166/vkzd6462

Abstract

A Cesarean section (C-section) is a surgical procedure involving an incision into the abdominal wall and uterus to deliver a baby. This procedure disrupts tissue continuity and nerve endings, resulting in pain at the incision site post-surgery. Lavender aromatherapy is a non-pharmacological pain management technique that has been shown to alleviate pain. This study aims to evaluate the effect of lavender aromatherapy on reducing pain intensity in patients post-Cesarean section in the Marjan Bawah Room at Dr. Slamet Garut General Hospital. This descriptive study used a case study design. The Numeric Rating Scale (NRS) was used as the instrument to measure pain intensity in patients. Pain levels were assessed before and after applying lavender aromatherapy for three consecutive days. The case study revealed that the application of lavender aromatherapy significantly reduced pain intensity in post-Cesarean patients. Prior to the aromatherapy intervention, the patient's pain level was recorded as 6 (moderate pain). After three days of lavender aromatherapy, pain intensity decreased to 2 (mild pain). Lavender can effectively reduce pain intensity in post-Cesarean patients, suggesting its potential as a valuable adjunct in pain management strategies.