Claim Missing Document
Check
Articles

Found 34 Documents
Search

The Efficacy and Safety of Topical Gel Formulation of n-Hexane Fraction of Curcuma longa in Wound Healing of Hyperglycemic Mice Ietje Wientarsih; Wiwin Winarsih; Lina Noviyanti Sutardi
Jurnal Veteriner Vol 14 No 1 (2013)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.169 KB)

Abstract

Curcuma longa (turmeric) is one of the tropical plant belong to Zingiberaceae family. It has beneficialeffects in healing of variety diseases. The aim of this study was to evaluate the efficacy and safety of  atopical gel formulation of n-hexane fraction of Curcuma longa in the wound healing of hyperglycemic mice.A total of 30 hyperglycemic mice were divided into three groups. They were given topical application, NC asa negative control (gel base), PC as a positive control (Neomycine sulfate 5%), treated groups (HF = n-hexane gel). Histopathological examination of the skin was performed to evaluate the wound healing.  Theresult showed that, there were no changes on tha appearance of the gel preparation, physically.  Evethoughupon the pH determination of the gel at six month of storage at 40ºC there were significant difference.  Theeffect of n-hexane gel, in terms of decreasing the surface area of wound and histopathological characteristicswere significantly (p <0.05) different between the PC group and HF group.  Skin irritant test showedneither rashes, swelling, inflammation, redness, irritation, itching nor any other toxicity  symptoms followingapplication of the gel. Significant effect of n hexane fraction of C. longa gel on wounds without any adversedermal toxic effects sounds very promising and it may be employed in the management of diabetic wound.
Aktivitas Penyembuhan Luka oleh Gel Fraksi Etil Asetat Rimpang Kunyit pada Mencit Hiperglikemik (WOUND HEALING ACTIVITY OF AETHYL ACETATE OF CURCUMA LONGA GEL IN HYPERGLYCEMIC MICE) Ietje Wientarsih; Wiwin Winarsih; Lina Noviyanti Sutardi
Jurnal Veteriner Vol 13 No 3 (2012)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.487 KB)

Abstract

Traditional remedies generally use plant based therapies for treatments. The availability of plantfor treatments is relatively abundant in Indonesia, whether as treatments for diabetic wounds or antiinflammation. Curcuma longa Linn has been reported as an alternative treatment for several diseasesincluding wound healing. The aim of this study was to investigate the possible effect on wound healing ofethyl acetate of C.longa gel in skin hyperglycemic mice. The ethyl acetate of C.longa gel was evaluated toassess its healing efficiency on excision wound. Thirty mice were used in this study. The mice were dividedinto three groups i.e.: KN as a negative control (without treatment), KP as a positive control (Neomycinsulfate), and treated groups (GE= ethyl acetate gel). There was a significant effect on histopathologicalcharacteristics in wound healing of treated mice with ethyl acetate gel compared with KN mice. It seemthat C.longa gel is a potential for phyto-therapeutic agent in management of wound healing.
Uji Toksisitas Akut Ekstrak Rimpang Kunyit pada Mencit : Kajian Histopatologis Lambung, Hati dan Ginjal (ACUTE ORAL TOXICITY OF TURMERIC EXTRACT IN MICE : HISTOPATHOLOGICAL STUDIES OF STOMACH, LIVER AND KIDNEY) Wiwin Winarsih; Ietje Wientarsih; Nova P. Sulistyawati; Istifharany Wahyudina
Jurnal Veteriner Vol 13 No 4 (2012)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.192 KB)

Abstract

This experiment was carried out to determine the mouse lethal dose (MLD50 of ethanolic extract ofthe turmeric (Curcuma longa) rhizomes following single oral administration and to evaluate thetoxicopathologic effects of the extract in certain organs ie stomach, liver and kidney. Forty five male micewere divided into nine groups. Four groups were treated orally with ethyl acetate fraction, four groups weretreated orally with hexane fraction of ethanolic turmeric extract, and one group was used as control. Theethyl acetate fraction groups were administered orally with the ethyl acetate fraction at doses of 7.5, 1.5,30 and 60 g/kg body weight. The hexane fraction groups were administered orally with the hexane fractionwith the dosage of 7,5, 15, 30 and 60 g/kg body weight. The control group received normal saline. MLD50 ofethyl acetate fraction was 27,98 gram/kg body weight by per oral administration. Oral MLD50 of hexanefraction was 19,50 gram/kg body weight. Histopathological features of the ethyl acetate and hexanefractions groups showed increased amount of parietal cells in stomach and parenchymal degeneration andnecrosis in their liver and kidney.
Frekuensi Penggunaan Obat Antifungal untuk Dermatofitosis pada Kucing di Klinik Hewan Starvet Bogor Tahun 2017 dan 2018 Miyati Sofariah; Bayu Febram; Wiwin Winarsih
Jurnal Health Sains Vol. 2 No. 7 (2021): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v2i7.222

Abstract

Dermatofitosis is a superficial fungal infection of the skin that is often found attacking pets such as cats. The disease is easy to occur in an atmosphere with high temperatures and humidity. Administration of antifungal drugs is usually done to treat and prevent cases of dermatofitosis. The purpose of this study is to describe the frequency of use of antifungal drugs in handling cases of dermatofitosis in veterinary clinics of research objects. The research was conducted descriptively using 39 medical record data from patients infected with dermatofita. The results showed antifungal drugs used for cases of dermatofitosis as much as twice the use of ketoconazole, 25 times the use of itraconazole, 11 times the use of blended ointments, and one use of griseofulvin. Based on the results of the study, itraconazole is the most widely used antifungal drug to handle cases of dermatofitosis in veterinary clinics
SPECIAL BONE MEAL PRODUK HIDROLISIS ALKALI PADA TULANG AYAM Denny Rusmana; Rachmat Wiradimadja; Fitri Apriani Noor; Intan Mayasaroh; Wiwin Winarsih
ZIRAA'AH MAJALAH ILMIAH PERTANIAN Vol 41, No 3 (2016)
Publisher : Pusat Publikasi Jurnal Universitas Islam Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/zmip.v41i3.539

Abstract

The study aims to determine the effect of some alkaline hydrolysis to decolagenation , Ca and P content of chicken bones to produce Special Bone meal. Research using experimental design completely randomized nested (6X2), which consists of factor A are the type of Alkali (filtrat Abu Sekam (FAS) 10%, FAS 20%, KOH 2% KOH 4%, NaOH 2%, and NaOH 4% ) and factor W is the immersion time (24 hours and 48 hours) with each treatment was repeated five. The results showed that the type of alkali significantly affect (p≤0.05) decolegenation, the content of Ca and P chicken bones, while the immersion time factor significantly affected (p≤0.05) decolagenation and P content of chicken bones, but not significantly affect (p>0.05) the Ca content of chicken bones. Special Products Bone Meal best chicken bone obtained from the hydrolysis of chicken bone by 4% NaOH with a soaking time of 48 hours. With the ability decolagenation 60 ± 1.82% and the content of Ca, P, respectively 25.59 ± 0.57%, and 12.57 ± 0.26%
Apakah Kinerja Keuangan Perusahaan Konstruksi Di Bursa Efek Indonesia Dipengaruhi Penerapan PSAK72? Aries Veronica; Widarti Widarti; Dwi Yanti; Yeni Alfiana; Nivea Nivea; Wiwin Winarsih
Jurnal Media Akuntansi (Mediasi) Vol. 5 No. 2 (2023): Jurnal Media Akuntansi (MEDIASI), Maret 2023
Publisher : Universitas PGRI Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/jmediasi.v5i2.11344

Abstract

ABSTRACT This study aims to see whether before and after the implementation of PSAK72 will affect the performance of financial construction companies that are on the Indonesia Stock Exchange. The data used is secondary data with a population of 24 issuers. The research sample was based on purposive data collection techniques with certain criteria obtained by 21 issuers throughout 2018-2020. The analysis technique used is quantitative descriptive. The Wilcoxon Signed Rank Test was used as an analytical test tool in this study. The test results show that before and after the implementation of PSAK 72 does not affect financial performance as represented by the current ratio, debt to equity ratio, and net profit margin. This means that this research adds to previous empirical research evidence which states that there is no effect of PSAK72 implementation on financial performance. The adoption of PSAK72 does not necessarily significantly increase or decrease a company's financial performance. Keywords : Financial Performance, Financial Ratio, PSAK72 ABSTRAK Penelitian ini bertujuan melihat apakah sebelum dan sesudah penerapan PSAK72 akan mempengaruhi kinerja keuangan perusahaan konstruksi yang ada di Bursa Efek Indonesia. Data yang digunakan adalah data sekunder dengan populasi berjumlah 24 emiten. Sampel penelitian berdasarkan teknik pengumpulan data secara purposif dengan krieria tertentu diperoleh sebanyak 21 emiten sepanjang tahun 2018-2020. Teknik analisis yang digunakan deksriptif kuantitatif. Uji Wilcoxon Signed Rank Test digunakan sebagai alat uji analisis dalam penelitian ini. Hasil uji menunjukkan bahwa sebelum dan sesudah penerapan PSAK 72 tidak mempengaruhi kinerja keuangan yang diwakilkan oleh current ratio, debt to equity ratio, dan net profit margin. Artinya penelitian ini menambah bukti empiris penelitian sebelumnya yang menyatakan bahwa tidak adanya pengaruh penerapan PSAK72 terhadap kinerja keuangan. Penerapan PSAK72 belum tentu meningkatkan atau menurunkan kinerja keuangan perusahaan secara signifikan. Kata Kunci: Kinerja Keuangan, PSAK72, Rasio Keuangan
THE EFFECTS OF AGE ON BIOCHEMISTRY PROFILES OF ACEH CATTLE BLOOD Lia Khairita; Anita Esfandiari; Sus Derthi Widhyari; Wiwin Winarsih
Jurnal Kedokteran Hewan Vol 15, No 3 (2021): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (374.524 KB) | DOI: 10.21157/j.ked.hewan.v15i3.21698

Abstract

The purpose of this study was to analyze the effects of age on the biochemistry profiles of aceh cattle, which  included examinations of: total protein (TP), albumin, globulin, albumin/globulin ratio (A/G), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), creatine kinase (CK), blood urea nitrogen (BUN), calcium (Ca), phosphorus (P) and magnesium (Mg) . Sixteen clinically healthy aceh cattle aged 2-4 years old, and 16 aceh cattle aged 4-6 years old were purposively selected for the study. Blood samples were drawn from the jugular vein and subjected to blood biochemistry measurements using commercial kits. The results showed that serum concentrations of TP, globulin, AST and Ca of aceh cattle were significantly (P0.05) higher in age group 4-6 years old, while ALP activity was significantly (P0.05) higher in age group 2-4 years old. In conclusion, age must be considered as a factor when interpreting the blood biochemistry profiles of aceh cattle.
Upaya peningkatan pengetahuan ibu melalui penyuluhan dan pemeriksaan tumbuh kembang pada balita Setyo Retno Wulandari; Wiwin Winarsih; Istichomah Istichomah
Jurnal Pengabdian Harapan Ibu (JPHI) Vol 4 No 2 (2022): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (567.148 KB) | DOI: 10.30644/jphi.v4i2.706

Abstract

Pertumbuhan dan perkembangan bayi/balita yang baik sesuai dengan usianya merupakan prioritas bagi orang tua. Tumbuh kembang pada bayi/balita merupakan proses yang sangat penting bagi kehidupan anak. Masa lima tahun pertama atau dikenal dengan istilah golden periode, merupakan masa bertumbuh dan berkembang anak yang akan menentukan masa depannya baik secara fisik, mental maupun perilaku anak nantinya. Upaya yang dapat dilakukan guna mencegah terjadinya masalah pada pertumbuhan dan perkembangan bayi/balita adalah dengan melakukan Stimulasi, Deteksi dan Intervensi Dini Tumbuh Kembang (SDIDTK) dan didukung dengan pengetahuan ibu yang baik terkait pertumbuhan dan perkembangan bayi balita. Tujuan dari kegiatan pengabdian ini diharapkan dapat meningkatkan pengetahuan ibu tentang stimulasi, deteksi dan intervensi dini tumbuh kembang anak usia 0 – 5 tahun secara berkala serta mendeteksi penyimpangan pertumbuhan dan perkembangan secara dini. Metode pengabdian ini dengan melakukan penyuluhan melalui ceramah dan interaksi tanya jawab serta dilakukan pemeriksaan SDIDTK dengan form KPSP. Kegiatan penyuluhan diikuti oleh 17 ibu balita, sedangkan stimulasi tumbuh kembang ini diikuti oleh 17 bayi balita berusia 0-5 tahun. Hasil pemeriksaan SDIDTK didapatkan 14 bayi/balita perkembangannya sesuai dengan usianya sedangkan 3 balita lainnya memiliki perkembangan yang meragukan.
THE EFFECTS OF AGE ON BIOCHEMISTRY PROFILES OF ACEH CATTLE BLOOD Lia Khairita; Anita Esfandiari; Sus Derthi Widhyari; Wiwin Winarsih
Jurnal Kedokteran Hewan Vol 15, No 3 (2021): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v15i3.21698

Abstract

The purpose of this study was to analyze the effects of age on the biochemistry profiles of aceh cattle, which  included examinations of: total protein (TP), albumin, globulin, albumin/globulin ratio (A/G), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), creatine kinase (CK), blood urea nitrogen (BUN), calcium (Ca), phosphorus (P) and magnesium (Mg) . Sixteen clinically healthy aceh cattle aged 2-4 years old, and 16 aceh cattle aged 4-6 years old were purposively selected for the study. Blood samples were drawn from the jugular vein and subjected to blood biochemistry measurements using commercial kits. The results showed that serum concentrations of TP, globulin, AST and Ca of aceh cattle were significantly (P0.05) higher in age group 4-6 years old, while ALP activity was significantly (P0.05) higher in age group 2-4 years old. In conclusion, age must be considered as a factor when interpreting the blood biochemistry profiles of aceh cattle.
Peranan Lingkungan Kerja Terhadap Kinerja Karyawan PT. Musi Prima Karsa Palembang Wiwin Winarsih; Aries Veronica; Efidiyana Efidiyana
Jurnal Manajemen dan Investasi (MANIVESTASI) Vol. 2 No. 2 (2020): Jurnal Manajemen Dan Investasi (MANIVESTASI), Desember 2020
Publisher : Universitas PGRI Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/jmanivestasi.v2i2.5272

Abstract

ABSTRACT This study aims to determine the role of the work environment on the performance of employees of PT Musi Prima Karsa Palembang. The work environment is one of the main supporting factors in the wheels of the company, therefore the work environment must be considered and this is where the job of a company leader is to pay attention to, fix and organize the work environment so that employees can work in the company properly. This research was conducted using qualitative analysis techniques with data collection methods, interviews and library research. Based on the research results, it can be concluded that there is a role for the work environment on employee performance. In the future, research can be used for the development of physical work environments and non-physical work environments in improving the performance of employees of PT Musi Prima Karsa Palembang. Keywords: work environment, employee performance ABSTRAK Penelitian ini bertujuan untuk mengetahui peranan lingkungan kerja terhadap kinerja karyawan PT Musi Prima Karsa Palembang. Lingkungan kerja sebagai salah satu faktor yang merupakan pendukung utama dalam roda perusahaan, karena itu lingkungan kerja harus diperhatikan dan disinilah tugas seorang pimpinan perusahaan memperhatikan, membenahi serta menata lingkungan kerja agar karyawan dapat bekerja dalam perusahaan dengan baik. Penelitian ini dilakukan dengan teknik analisis kualitatif dengan metode pengumpulan data, wawancara dan riset kepustakaan. Berdasarkan hasil penelitian dapat disimpulkan terdapat peranan lingkungan kerja terhadap kinerja karyawan. Kedepannya, penelitian dapat digunakan untuk pengembangan lingkungan kerja fisik dan lingkungan kerja non fisik dalam meningkatkan kinerja karyawan PT Musi Prima Karsa Palembang Kata kunci : Lingkungan kerja, Kinerja  Karyawan