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All Journal Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN Indonesian Journal of Pharmaceutical Science and Technology Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional Jurnal Pendidikan Informatika dan Sains SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Al-Khidmah BULETIN AL-RIBAATH PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Journal Syifa Sciences and Clinical Research (JSSCR) Indonesian Journal of Pharmaceutical Education Sinteza Jurnal Sains dan Kesehatan Journal of Pharmascience
Hadi Kurniawan
Jurusan Farmasi, Fakultas Kedokteran, Universitas Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Pontianak 78124, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Pengaruh Variasi Konsentrasi Karaginan Kombinasi Emulgator Anionik dan Nonionik Terhadap Formulasi Losion Astaxanthin Ekstrak Minyak Cincalok Nia Risnawati; Siti Nani Nurbaeti; Hadi Kurniawan
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.272

Abstract

ABSTRACT Cincalok is a typical food of West Kalimantan, Indonesia. Cincalok is made from the fermentation of rebon shrimp, which contains astaxanthin compounds inside them. Astaxanthin has strong antioxidant properties with an IC50 value of 18.75 ppm. Astaxanthin from cincalok oil extract can be formulated into a lotion for skin care. Lotion were made in 4 formulas. Formula F1 and F2 used a combination of anionic emulgators (stearic acid and TEA), formulas F3 and F4 used a combination of nonionic emulgators (Span 60 and Tween 60). Concentration carrageenan as a viscosity agent was 0.75% in F1 and F3, and concentration of 1% in F2 and F4. All formulas were tested for their physical properties such as other organoleptic test, homogenity, spreadibility, adhesion, pH , viscosity, and globul size. Lotion were also tested for astaxanthin levels contained in lotion. The results showed that the formula F3 was the best formula based on physical properties and astaxanthin levels test in lotion. Keywords: Astaxanthin, Anionic, Cincalok, Lotion, Nonionic
Analisis Kadar Kalium Ekstrak Kombinasi Kulit Pisang (Musa paradisiaca L.) dan Kulit Nanas (Ananas comosus (L.) Merr) Secara Spektrofotometri Serapan Atom: Analysis of Potassium Levels in Combination Extracts of Banana Peels (Musa paradisiaca L.) and Pineapple Peels (Ananas comosus (L.) Merr) by Atomic Absorption Spectrophotometry Fajar Nugraha; Pratiwi Apridamayanti; Hadi Kurniawan; Inarah Fajriaty; Siti Nani Nurbaeti; Liza Pratiwi; Safrilla Anggraeni
Jurnal Sains dan Kesehatan Vol. 3 No. 6 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i6.791

Abstract

Penggunaan buah pisang dan nanas yang banyak untuk berbagai olahan makanan akan menghasilkan penumpukan limbah kulit. Limbah kulit pisang dan nanas diketahui mengandung unsur kalium yang dapat diolah kembali untuk menjadi produk yang bermanfaat. Oleh karena itu, penelitian ini dilakukan untuk melihat kadar kalium terhadap ekstrak kombinasi kulit pisang dan kulit nanas dengan menggunakan spektrofotometer serapan atom. Metode: pembuatan ekstrak kental dilakukan dengan metode infundasi atau infusa yang dikeringkan. Ekstrak kental didestruksi dengan cara pengabuan menggunakan tanur. Kemudian dilakukan pengujian kadar kalium menggunakan spektrofotometer serapan atom pada panjang gelombang 766,5 nm. Hasil penelitian menunjukkan kalium pada ekstrak kental didapatkan sebanyak 47,483 mg/g ekstrak. Kesimpulan: ekstrak kombinasi kulit pisang dan kulit nanas mengandung kalium yang berpotensi dalam menunjang kebutuhan kalium di dalam tubuh.
Sosialisasi masyarakat melalui demonstrasi pembuatan produk kesehatan sebagai upaya meningkatkan pengetahuan dalam pencegahan penyakit dispepsia di Kelurahan Siantan Hulu Hadi Kurniawan; Inarah Fajriaty; The Hezkiel David Julian; Salma Nursapni; Nanda Amelia; Layla Syamsa
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 5 (2025): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i5.33523

Abstract

Abstrak Dispepsia merupakan salah satu masalah kesehatan dengan prevalensi tinggi di Indonesia, termasuk di Kelurahan Siantan Hulu, Pontianak Utara, Kalimantan Barat, di mana tercatat 519 kasus pada Januari–Mei 2025. Kurangnya pengetahuan mengenai penyebab, pencegahan, dan penanganan dispepsia menjadi perhatian utama. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan dan kesadaran masyarakat tentang dispepsia serta memperkenalkan pemanfaatan herbal lokal sebagai alternatif terapi. Kegiatan dilaksanakan bersama mitra ibu PKK, perangkat RT/RW, serta siswa/i SMKN 6 Pontianak, dengan total 61 peserta terlibat. Metode pelaksanaan berupa pelatihan praktis disertai pre-test dan post-test. Hasil evaluasi menunjukan peningkatan pengetahuan peserta dari rata-rata 75,52 (pre-test) menjadi 83,06 (post-test), atau naik 9,98%. Sebanyak 50,7% peserta menilai kegiatan ini baik dan 45,9% menilai sangat baik. Kegiatan juga berhasil menumbuhkan minat masyarakat dalam pemanfaatan dan pembuatan herbal lokal untuk upaya pencegahan penyakit saluran cerna. Kata kunci: dispepsia; edukasi kesehatan; tanaman herbal; masyarakat; Siantan Hulu. Abstract Dyspepsia is a common health problem with a high prevalence in Indonesia, including in Siantan Hulu Village, North Pontianak, West Kalimantan, where 519 cases were recorded from January to May 2025. Lack of knowledge about the causes, prevention, and management of dyspepsia is a primary concern. This community service activity aims to increase public knowledge and awareness about dyspepsia and introduce the use of local herbs as an alternative therapy. The activity was conducted together with partners from the PKK women's group, neighborhood officials (RT/RW), and students of SMKN 6 Pontianak, involving a total of 61 participants. The implementation method consisted of practical training accompanied by pre-tests and post-tests. Evaluation results showed an increase in participants' knowledge from an average score of 75.52 (pre-test) to 83.06 (post-test), an improvement of 9.98%. Approximately 50.7% of participants rated the activity as good and 45.9% as very good. The activity also succeeded in fostering community interest in utilizing and making local herbal remedies for the prevention of digestive tract diseases. Keywords: dyspepsia; health education; herbal plants; community; Siantan Hulu.
Formulasi Mouthwash Kulit Jeruk Pontianak (Citrus nobilis Lour. Var. microcarpa) dan Uji Aktivitas terhadap Bakteri Streptococcus mutans Meri Ropiqa; Hadi Kurniawan; Sabila Mayesa
Sinteza Vol. 5 No. 2 (2025): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v5i2.31603

Abstract

Preserving dental and oral hygiene is essential to maintain the overall function of the oral cavity. Essential oil extracted from Pontianak orange peel shows potential as a safe and effective component for oral healthcare when incorporated into a mouthwash formulation. This research was conducted to evaluate the potential of Pontianak orange peel essential oil as an antibacterial mouthwash effective against Streptococcus mutans. The study was conducted by formulating mouthwash preparations using different concentrations of Pontianak orange peel essential oil: 3%, 4%, and 5%, followed by evaluation of physical properties including organoleptic characteristics, homogenity, pH level, sedimentation, specific gravity, and viscosity. The antibacterial properties were tested using  the disc diffusion method.The physical evaluation results showed that the mouthwash had a sweet taste, green color, a citrus peel aroma with a hint of mint; it was homogeneous, with no sedimentation; had a pH value ranging from 5.13 ± 0.02 to 5.25 ± 0.02; specific gravity ranging from 0.9968 ± 0.06 to 1.0424 ± 0.00 g/ml; and viscosity ranging from 1.717 ± 0.02 to 1.920 ± 0.01mPa.s. All formulations met the physical property requirements of a good mouthwash to ensure comfort during use. The largest inhibition zone was observed at the highest essential oil concentration (5%), with a diameter of 8.04 ± 1.05 mm, which falls under the category of moderate antibacterial activity. This study indicates that a mouthwash containing 5% Pontianak orange peel essential oil is effective in inhibiting the growth of Streptococcus mutans.
Evaluating Acute Toxicity of Jamu Cekok in Rats: A Histopathological Approach Based on OECD 425 Michelle The; Puji Astuti; Siti Aisyah; Hadi Kurniawan
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1207-1217

Abstract

Jamu cekok, an Indonesian traditional medicine to increase children appetite, has not passed preclinical or clinical trials. The rhizomes that make up jamu cekok such as pakai bahasa latinnya contain ethyl p-methoxycinnamate which is toxic, thus potentially harmful to the children. Therefore in this study we aim to determine the Lethal Dose (LD50) value of jamu cekok using the OECD 425 method as well as to observed the histopathological change in the liver in female Rattus norvegicus L. This study used an analytical experimental design with the OECD 425 method to test the acute toxicity of jamu cekok. The test rats used were in accordance with the OECD 425 protocol with an additional 2 negative control rats. Jamu cekok in the form of decocta were given once on the first day of the acute toxicity test and observed for 14 days. On the 15th day, rats were euthanized, dissected, and hepatic organs were taken to make histopathological preparations with Hematoxylin-Eosin staining. Analysis of hepatic damage was assessed using Histopathology Scoring Manja Roenigk and tested by Kruskal Wallis method. The results showed the LD50 value of decocta extract of jamu cekok was >5000 mg/kgBB. Observations of body weight, behavioral tests, organ index, and macroscopic hepar of test rats showed no signs of toxicity. However, The statistical analysis for histopathology test showed that there was a significant difference (p<0.05) between the negative control group and the 5000 mg/kgBB treatment group. In conclusion, the administration of jamu cekok was categorized as practically non-toxic but it can caused reversible hepatic damage at a dose of 5000 mg/kgBB.
Analisis Kandungan Nitrit pada Sarang Burung Walet (Edible-Nest Swiftlet) dari Kabupaten Sintang Menggunakan Metode Spektrofotometri Uv – Vis Selly Afani; Hadi Kurniawan; Fajar Nugraha
Journal of Pharmascience Vol. 11 No. 1 (2024): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.17170

Abstract

Sarang dari burung walet yang berwarna putih adalah sarang yang terbuat dari air liur burung walet spesies Collocalia fuchipaga. Dari segi keamanan pangan, terdapat cemaran kimia yang harus diperiksa pada sarang burung walet yang dapat mempengaruhi kesehatan manusia, yaitu nitrit. Tujuan dari penelitian ini yaitu untuk memeriksa kadar nitrit pada sarang burung walet yang diambil dari rumah burung walet asal Kabupaten Sintang. Penentuan kadar nitrit dalam sampel dilakukan secara kuantitatif dengan menggunakan spektrofotometri UV-Vis. Analisis nitrit menggunakan Spektrofotometri menunjukkan bahwa kandungan nitrit bervariasi pada 4 sampel sarang walet dari 4 lokasi yang berbeda secara berturut-turut yaitu 77,823 mg/kg ; 14,795 mg/kg ; 46,645 mg/kg dan 218,112 mg/kg, serta nitrit yang terkandung pada sampel walet yang telah dilakukan proses pencucian berulang pada sampel lokasi 1 yaitu sebesar 4,148 mg/kg. Hasil ini menunjukkan bahwa terdapat satu sampel sarang burung walet tidak bersih melewati batas keamanan yang diatur oleh pemerintah Indonesia yaitu 80 mg/kg. Penelitian ini juga menunjukkan bahwa praktik budidaya yang baik harus diperkenalkan kepada petani burung walet dan pentingnya proses pencucian berulang sebelum mengolah walet kepada masyarakat. Kata Kunci: Keamanan Pangan, Uji Kualitatif, Sintang, Collocalia fuchipaga, Analisis Nitrit The white swallow's nest is a nest made from the saliva of the Collocalia fuchipaga species. In terms of food safety, there are chemical contaminants that must be examined in swiftlet nests that can affect human health, namely nitrites. This study aims to examine the levels of nitrites in swallow nests taken from swallow houses from Sintang Regency. Determination of nitrite levels in samples was carried out quantitatively using UV-Vis spectrophotometry. Nitrite analysis using spectrophotometry showed that the nitrite content varied in 4 swallow nest samples from 4 different locations, namely 77.823 mg/kg; 14.795 mg/kg ; 46.645 mg/kg and 218.112 mg/kg, as well as the nitrite content in swallow samples that have been subjected to repeated washing processes at sample location 1 which is 4.148 mg/kg. These results indicate that there is one sample of unsanitary swiftlet nests that exceeds the safety limit set by the Indonesian government, namely 80 mg/kg. This research also shows that good swallow nest cultivation practices must be introduced to swiftlet farmers and the importance of repeated washing processes before processing swallows to the community.
Analisis Kandungan Natrium Siklamat pada Manisan Buah Mangga yang Dijual di Kota Pontianak Menggunakan Metode Spektrofotometri UV Nabila Nuraini; Hadi Kurniawan; Fajar Nugraha
Journal of Pharmascience Vol. 11 No. 2 (2024): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.18074

Abstract

Natrium siklamat umumnya ditambahkan pada manisan buah mangga untuk memperbaiki cita rasa produk. Penggunaan natrium siklamat pada manisan mangga dicurigai tidak sesuai dengan kadar yang tercantum dalam Peraturan BPOM Nomor 11 Tahun 2019. Kondisi ini dapat menimbulkan efek yang berbahaya pada tubuh. Penelitian ini dilakukan untuk mengidentifikasi, menghitung kadar dan mengevaluasi kadar natrium siklamat pada manisan mangga yang dijual di kota Pontianak. Identifikasi natrium siklamat dilakukan secara kualitatif melalui metode pengendapan dengan pereaksi HCl, BaCl2, dan NaNO2. Sedangkan, penentuan kadar natrium siklamat dalam sampel secara kuantitatif dilakukan dengan spektrofotometri UV pada panjang gelombang maksimum 313,4 nm. Hasil uji kualitatif menunjukkan 3 dari 5 sampel manisan mangga dengan kode A, B, dan E mengandung natrium siklamat. Sementara itu, hasil uji kuantitatif menunjukkan kadar sampel A sebesar 255,824 mg/kg, kadar sampel B sebesar 352,49 mg/kg, dan kadar sampel E sebesar 125,743 mg/kg. Hasil ini menunjukkan kadar natrium siklamat yang digunakan masih berada dibawah batas maksimal konsumsi yang tercantum dalam Peraturan BPOM Nomor 11 Tahun 2019 yaitu sebesar 500 mg/kg. Kata Kunci: Keamanan Pangan, Uji Kualitatif, Uji Kuantitatif, Bahan Tambahan Pangan, Metode Pengendapan Sodium cyclamate is generally added to candied mangoes to improve the taste of the product. It is suspected that the use of sodium cyclamate in candied mangoes does not comply with the levels stated in BPOM Regulation Number 11 of 2019. This condition can cause dangerous effects on the body. This research was conducted to identify, calculate levels and evaluate sodium cyclamate levels in mango sweets sold in the city of Pontianak. Sodium cyclamate identification was carried out qualitatively through the precipitation method with HCl, BaCl2 and NaNO2 reagents. Quantitative determination of sodium cyclamate levels in samples was carried out using UV spectrophotometry at a maximum wavelength of 313.4 nm. Qualitative test results showed that 3 out of 5 samples of mango sweets with codes A, B and E contained sodium cyclamate. Meanwhile, quantitative test results showed that sample A levels were 255.824 mg/kg, sample B levels were 352.49 mg/kg, and sample E levels were 125.743 mg/kg. These results show that the levels of sodium cyclamate used are still below the maximum consumption limit stated in BPOM Regulation Number 11 of 2019, namely 500 mg/kg.
The Effect of Dekokta Jamu Cekok on Short Term Memory of White Rats (Rattus norvegicus L.) Male Wistar Strain Nelli Jaliyanti; Puji Astuti; Hadi Kurniawan; Ery Hermawati; Alex Alex
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.519-524

Abstract

The rising prevalence of dementia in Indonesia has resulted in a decline in memory and cognitive abilities. This condition is believed to be linked to oxidative stress caused by an imbalance between free radicals and antioxidants. Jamu cekok, a traditional herbal remedy composed of rhizomes such as Kaempferia galanga, Zingiber officinale, Curcuma longa L., and Curcuma xanthorrhiza, is known for its antioxidant properties. These antioxidants have the potential to neutralize free radicals, thereby helping to prevent degenerative diseases like dementia and Alzheimer’s, which are associated with short-term memory impairment. This study aimed to evaluate the effects of jamu cekok decoction on the short-term memory of male Wistar rats (Rattus norvegicus L.). A laboratory-based experimental study with a post-test-only control group design was conducted. Male Wistar rats were divided into three treatment groups receiving jamu cekok doses of 100, 200 and 400 mg/kg BW, and a negative control group was included. Short-term memory was assessed using the Y-maze test. The highest Y-maze alternation percentage of 65.12% was observed in the treatment group receiving a dose of 400 mg/kg BW. However, statistical analysis using the Kruskal-Wallis test showed no significant difference in Y-maze alternation percentages among the groups receiving jamu cekok (p = 0.626). The findings indicate that jamu cekok decoction did not have a significant effect on the short-term memory of male Wistar rats. Further studies with larger sample sizes and alternative assessment methods are recommended to explore its potential cognitive benefits.
Co-Authors Adelita Ahyanurri Adnan Pramudio Alex Alex Alifian, Ridho Firza Andhi Fahrurroji Andi Andi Anis Marselia Aprianti, Indah Apridamayanti, Pratiwi Bambang WIJIANTO Bart Agus Raya Deisberanda, Fortunata Saesarria Dian Novita Sari Dwi I. Prayitno Efprio Nensa Kurniawan Ery Hermawati Fajar Nugraha Fajar Nugraha Fajar Nugraha Fajriaty, Inarah Hafrizal Riza Hariyanto IH Harli Frimana Hidayat, Kartika Nur Hiqbar Hiqbar Husnafa Patriani Iga Yastiara Iga Yastiara Khalishah, Hana Layla Syamsa Liza Pratiwi Margaretha Margaretha Melania Niken Safira Michelle The Nabila Nuraini Nanda Amelia Nelli Jaliyanti Nia Risnawati Novia Novia Nurul Fajriani Pratiwi Apridamayanti Pratiwi Apridamayanti Pratiwi Apridamayanti, Pratiwi Puji Astuti Rico Arianto Ropiqa, Meri Sabila Mayesa Safrilla Anggraeni Salma Nursapni Selly Afani Shoma Rizkifani Siti Aisyah Siti Nani Nurbaeti Sri Wahdaningsih Thamrin Usman The Hezkiel David Julian Tiara Bella Pratiwi Virgilius Alleandro Tuah Talu Winda Rahmalia Yuswar, Muhammad Akib