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All Journal JOURNAL OF COASTAL DEVELOPMENT Jurnal Kimia Riset Indonesian Journal of Chemical Science Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Chemistry Dinamisia: Jurnal Pengabdian Kepada Masyarakat Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Abdi: Media Pengabdian Kepada Masyarakat Studies in Philosophy of Science and Education PROFICIO: Jurnal Pengabdian Masyarakat Berkala Penelitian Hayati Jurnal Pijar MIPA Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Unesa Journal of Chemistry Jurnal Manusia dan Lingkungan Bulletin of Chemical Reaction Engineering & Catalysis Indonesian Journal of Chemical Science Jurnal Pendidikan MIPA Folia Medica Indonesiana ABISATYA: Journal of Community Engagement
Sari Edi Cahyaningrum
Universitas Negeri Surabaya
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Social Sciences Other

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Journal : Jurnal Pijar MIPA

 1 
Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus Indira Dwi Aulia; Sari Edi Cahyaningrum
Jurnal Pijar Mipa Vol. 18 No. 4 (2023): July 2023
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v18i4.4994

Abstract

Binahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against Staphylococcus aureus bacteria. It was a true experimental study with data collection carried out at the inorganic level. This study's results show that the gel preparation's organoleptic test meets the requirements for skin pH of 4.5-6.5. The spreading test meets the need for good distribution on the skin, which is 5-7cm. The antibacterial activity test showed that the largest diameter of the inhibition zone was observed at concentration F5 (5% binahong leaf extract), which was 13.4 mm.
Synthesis and characterization of hydroxyapatite-nanosilver-clove oil (Eugenia Caryophyllus) as antibacterial in toothpaste preparations against streptococcus mutans bacteria Browi Nugroho; Sari Edi Cahyaningrum
Jurnal Pijar Mipa Vol. 18 No. 4 (2023): July 2023
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v18i4.5325

Abstract

The formation of dental caries results from the activity of Streptococcus mutans bacteria. One of the efforts to prevent dental caries is using toothpaste containing antibacterial compounds such as hydroxyapatite-nanosilver-clove oil. This study aims to synthesize and characterize hydroxyapatite-nanosilver-cloves oil as an antibacterial that causes dental caries. In this study, physical properties were tested, namely, particle size with PSA, spreadability, stickiness, homogeneity, and chemical properties tested in functional groups with FTIR, pH, and antibacterial activity with the disc diffusion method. This study used 2% hydroxyapatite, ten ppm nanosilver, tween 80, xanthan gum, 70% sorbitol, sodium benzoate, sodium lauryl sulfate, sodium saccharin, calcium carbonate, peppermint, distilled water, clove oil with variations in the addition of concentrations of 1%, 2%, 3%, and 4%. The synthesis results produced a toothpaste preparation made from hydroxyapatite-nanosilver-clove oil, as evidenced by the results of FTIR characterization showing the presence of OH-, CO32-, PO43-, C-H, C-O, and C=O functional groups. PSA results show hydroxyapatite-nanosilver-clove oil has an average size of 4464 nm which is not included in the nanoparticle category (<100 nm). The toothpaste spreadability test resulted in a spread diameter of 5-6 cm, which met the requirements for paste spreadability (5-7 cm), while the adhesion test resulted in adhesion (7-12 seconds) which has not met the ideal requirements (1-6 seconds). The pH measurement resulted in a toothpaste pH of 8.8-9.0 per SNI (4.5-10.5). The homogeneity test of the toothpaste has met the requirements according to SNI, namely the absence of air bubbles, clumps, and separated particles. The antibacterial activity test showed that the hydroxyapatite-nanosilver-clove oil toothpaste formulation was able to inhibit the growth of S.mutans bacteria with the highest inhibition diameter in the variation of adding 4% concentration of clove oil, namely 14.99 mm with normally distributed data (p>0.05). One Way ANOVA statistical analysis showed that the treatment variation had a significantly different effect (p<0.05). These results indicate that adding clove oil into the formulation of hydroxyapatite-nanosilver-clove oil toothpaste can affect its chemical, physical, and antibacterial activity.
Effect of Urea Variation Concentration on Slow Release Fertilizer (SRF) Based Chitosan/NaTPP/Calcium Wijayanti, Alvia Rachma; Cahyaningrum, Sari Edi
Jurnal Pijar Mipa Vol. 19 No. 5 (2024): September 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i5.7401

Abstract

Environmental pollution due to urea can negatively impact the environment and its surroundings. Efforts to prevent environmental pollution include encapsulating urea made of chitosan/NaTPP/Ca, which aims to determine its physical and chemical properties. This study crosslinks chitosan 1.66%, with NaTPP 3.33%, CaO, with variations in the addition of urea concentrations of 0.05%, 0.1%, 0.15%, 0.2%, and 0.25%. The results of FTIR characterization showed that there were functional groups OH-, C-H, Ca-O, NH, and P=O. The membrane weight yield ranges from 0.14-0.16 grams, while the average membrane thickness is 0.15-0.35 mm. The water absorption test is 1.86-2.64%, and the membrane porosity result is 0.91-2,25%. This shows that the membrane with a base material of 1.66% chitosan and 3.33% NaTPP is the best.
Utilization of Hydroxyapatite-Chitosan-Bay Leaf Oil (Syzygium Polyanthum W.) as Antibacterial for Streptococcus Mutants Adriani, Sherly Wahyu; Cahyaningrum, Sari Edi
Jurnal Pijar Mipa Vol. 19 No. 1 (2024): January 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i1.6379

Abstract

Dental caries is a disease that can damage hard tooth tissue caused by the activity of Streptococcus mutans bacteria. Streptococcus mutans bacteria are the leading cause of dental caries disease. Efforts to prevent dental caries can be made using toothpaste, but toothpaste cannot reach areas that are difficult to reach with a toothbrush. Another method that can be used is mouthwash. This study was developed with the active ingredient compound HAp-chitosan-bay leaf oil in mouthwash to have an antimicrobial effect to prevent dental caries. This study aimed to determine the chemical physics characteristics and antibacterial activity of mouthwash preparations based on hydroxyapatite-chitosan-bay leaf oil. In this study, the active ingredients hydroxyapatite-chitosan-bay leaf oil was used with variations in the concentration of bay leaf oil, namely 0.5, 1.5, and 2.5 %. FT-IR characterization showed the presence of OH, N-H, CH, C=O, C=C, C-O, and PO43- functional groups. The pH test on the mouthwash showed compliance with the quality standard for mouthwash pH, which has a pH range of 5-7. The homogeneity test results in the mouthwash preparation showed no sediment or separation. Antibacterial activity testing showed that the HAp-chitosan-bay leaf oil mouthwash preparation inhibited the growth of Streptococcus mutans bacteria. The inhibition zone in the strong category with an average of 12.75 mm was shown in the HAp-chitosan-bay leaf oil mouthwash preparation formulation with a concentration of 2.5% bay leaf oil with the addition of sodium lauryl sulfate (SLS).
Synthesis, Characterization, and Antibacterial Activity Test of Chitosan–Nanosilver–Black Cumin Seed Oil (Nigella sativa) Gel Preparation against Staphylococcus aureus Bacteria Mustofa, Mohammad Nurul; Cahyaningrum, Sari Edi
Jurnal Pijar Mipa Vol. 21 No. 1 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i1.11306

Abstract

The skin is the outermost organ of the human body and functions as a protective barrier against environmental factors, making it susceptible to wounds caused by physical trauma and microbial infections. One pathogenic bacterium frequently associated with skin disorders such as boils, acne, and wound infections is Staphylococcus aureus. Therefore, topical formulations are required to prevent and manage infection. The combination of chitosan, nanosilver, and black cumin oil exhibits antibacterial activity and biocompatibility. This study aimed to evaluate the characteristics and antibacterial activity of a chitosan–nanosilver–black cumin oil gel against Staphylococcus aureus. The gel was formulated in five variations containing black cumin oil concentrations of 3%, 4%, 5%, 6%, and 7%. Chemical characterization was performed using Fourier Transform Infrared spectroscopy to identify functional groups, while nanosilver particle size was analyzed using a Particle Size Analyzer. Physical evaluation included a pH measurement to assess compatibility with the skin's pH. Antibacterial activity was determined by the disc diffusion method, measuring inhibition zone diameters. The Particle Size Analyzer results showed an average nanosilver particle size of 31.54 nm. FTIR analysis of the chitosan–nanosilver system confirmed the presence of O–H, N–H, C–H, and C=O functional groups, while FTIR characterization of black cumin oil confirmed the presence of functional groups associated with C–H stretching, C=O, C–O, and =C–H bending. The formulated gel exhibited a pH of 5.12–5.72, within the physiological pH range of human skin. Antibacterial testing demonstrated that inhibitory activity increased with increasing black cumin oil concentration, with the largest inhibition zone observed in the 7% formulation (21.67 mm). These findings indicate that chitosan–nanosilver–black cumin oil gel has potential for development as an antibacterial formulation.
Co-Authors 'Aisy, Khulud Rihadatul , INSIYAH Achmad Fitriadi Akbar Adriani, Sherly Wahyu Afifah, Fifi Ahmad Rudi Setiawan Akbar Izulhaq Akbar, Achmad Fitriadi AMARIA Amaria Amaria Amaria Amaria Amaria Amaria Amaria Amaria Andhega Wijaya Andika Pramudya Wardana Angelo Ranamanggala, Jonathan Arie Wardhono Astuti, Tsani Browi Nugroho Dewi Saputri, Ratih Dewi, Eryantika Cipta Dewinta Intan Laily Dharmawan, Anggi Putra Dina Kartika Maharani Dina Kartika Maharani DINA KARTIKA MAHARANI Dina Kartika Maharani ERIN WARDIANA, APRITA Eryantika Cipta Dewi Fadila, Syananda Zahra Fatma Listiandari, Intan Fifi Afifah Filza Qurrota 'Aini Fitriari Izzatunnisa Muhaimin Fitriari Izzatunnisa Muhaimin Hanifa Rachmah Kamila Hasanah Jusman, Nur Heryastuti, Nuniek I GUST MADE SANJAYA ILHAM FADILA RAMADHAN, MUHAMAD Indah Ardiningsih Indira Dwi Aulia ISNAWATI Jonathan Angelo Ranamanggala Lawarti, Riska Amelia Lazuardi, Gilang Pandu Leny Yuanita Leny Yuanita Lestari, Nanda Revita Dwi Lindawati, Zeti Luklukul Fitriyah Madaniyah, Safira Marena, Betari Maria Monica Sianita Maria Monica Sianita Maya Dany Puspitasari Mohammad As'ad Rosyadi Mudasir Mufarrihul Hazin Muhaimin, Fitriari Izzatunnisa Muhammad Amar Muhammad Turhan Yani MUSLIMIN IBRAHIM Mustaji Mustaji Mustaji Mustaji, Mustaji Mustofa, Mohammad Nurul N Narsito Nabil Nazhif Fikri Ahmad Nanda Onky Stefani Narsito Narsito Narsito Narsito Narsito Narsito Narsito Narsito Naw, Sin War Nita Kusumawati Novita Listiyani Nuniek Herdyastuti Nuniek Herdyastuti Nuniek Herdyastuti Nuniek Herdyastuti Nuniek Heryastuti Nur Qomariah Nurhayati Nurhayati Nurhayati Nurhayati Nurrohman Sidiq, Muhammad Nurtikasari, Ayu Wika Nurul Hidajati NURUL HIDAJATI Oce Wiriawan Perintis Gita Susanti Prima Retno Wikandari Puput Wanarti Rusimamto Purnamasari, Amalia Putri Rachma Indrarini Ratih Dewi Saputri Riska Amelia Lawarti Rudi Setiawan, Ahmad Rudiana Agustini Rudiana Agustini Rusmini Rusmini Rusmini Rusmini Rusmini Rusmini Sabirin Matsjeh Safira Madaniyah Satriawan, Muhammad Setiawan, Ahmad Rudi Setyono, Mohammad Iyo Agus Shifa Fauziyah Shifa Fauziyah Sin War Naw Soraya, Fathimah Sri Abidah Suryaningsih Sri Juari Santoso Sri Juari Santoso Sri Juari Santoso Sri Juari Santoso Sri Juari Santoso Sukarmin Sutoyo, Suyatno Suwandi, Sukma Yanti Putri Ayu Syananda Zahra Fadila Teguh Hari Sucipto, Teguh Hari Titik Taufikurohmah Titik Taufikurohmah Titik Taufikurrohmah Titik Taufikurrohmah Tri Joko Raharjo Tukiran TUKIRAN Tukiran Wahyudi, Ainaia Deaqiila Wijayanti, Alvia Rachma Yasfin Shafa Nurulisia Yossy Nur Annisa