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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Agromedicine and Medical Sciences Global Medical and Health Communication Jurnal Kebidanan Dan Kesehatan Tradisional Jurnal Kimia Mulawarman Majalah Kedokteran Sriwijaya Biomedical Journal of Indonesia Jurnal Farmasi Sains dan Komunitas Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Acta Biochimica Indonesiana SRIWIJAYA JOURNAL OF MEDICINE Molekul: Jurnal Ilmiah Kimia Jurnal Teknik Kimia Best Journal (Biology Education, Sains and Technology) Jurnal Ners Jurnal Abdi Insani Sriwijaya Journal of Ophthalmology Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Conferences of Medical Sciences Dies Natalis Proceedings National Conference Sisi Indonesia Global Medical and Health Communication
Fatmawati
Bagian Biokimia Dan Kimia Medik, Fakultas Kedokteran, Universitas Sriwijaya, Palembang, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Inhibitory Effect of Ethanol Extract of Cherry Mistletoe Leaves (Dendrophthoe pentandra (L.) Miq) on Xanthine Oxidase Enzyme Hana Daini Sabathania; Subandrate Subandrate; Sadakata Sinulingga; Safyudin Safyudin; Liniyanti D Oswari; Fatmawati Fatmawati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008252

Abstract

One plant that can be used as an alternative treatment for hyperuricemia is the cherry plant. The usefulness of these plants is due to the secondary metabolite compounds that can inhibit the enzyme xanthine oxidase. Cherry mistletoe is thought to have the same flavonoids, saponins, alkaloids, terpenoids, and tannins as the cherry plant, which can act as inhibitors. The aim of the study was to determine the inhibitory effect of an ethanol extract of cherry mistletoe leaves on the xanthine oxidase enzyme. This study was conducted as  an in vitro experimental study. Cherry mistletoe leaves were extracted with 96% ethanol. The extract was done with phytochemical screening, followed by an inhibition test on the xanthine oxidase enzyme using a spectrophotometer at a wavelength of 400 nm. Allopurinol was a positive control. The ethanol extract of cherry mistletoe leaves contains flavonoids, saponins, alkaloids, terpenoids, and tannins. The IC50 value of the ethanol extract of cherry mistletoe leaves was 23.44 mg/L. The ethanol extract of cherry mistletoe leaves has an inhibitory effect on the xanthine oxidase enzyme with moderate activity. Accordingly, the cherry mistletoe leaf extract can be considered as an alternative inhibitor of the xanthine oxidase enzyme in the control of hyperuricemia.
Analisis GC-MS Senyawa Aktif Dan Aplikasi Dalam Ekstrak Etanol Daun Simpur Air (Dillenia Suffruticosa L.) Dita Ardianti; Irfanuddin Irfanuddin; Fatmawati Fatmawati; Salmi Salmi
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 1 (2025): Juni 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i1.11139

Abstract

Daun simpur air  (Dillenia Suffruitcosa L.) secara tradisional telah banyak digunakan untuk mengobati berbagai penyakit seperti diare, demam, rematik, penyembuhan luka dan menghamat pertumbuhan sel kanker. Tanaman ini juga berpotensi menjadi sumber pengembangan produk kesehatan modern dengan berbagai metabolit sekunder yang memberikan kontribusi signifikan terhadap manfaat kesehatan, seperti flavonoid dan alkaloid, dengan sifat antioksidan dan antibakteri yang mendukung kesehatan. Tujuan penelitian ini untuk mengidentifikasi senyawa bioaktif dalam daun simpur air yang di ekstraksi menggunakan etanol 96%. Analisis dilakukan dengan menggunakan GC-MS untuk memisahkan, mengidentifikasi, dan menentukan struktur dan berat molekul senyawa. Identifikasi senyawa ekstrak etanol daun simpur air (Dillenia Suffruiticosa L) dengan GC-MS ditemukan 17 senyawa dengan enam senyawa dominan yaitu n-Hexadecanic Acid; γ-sitosterol; Neophytadine; Sitosterone; Octadecadienoic; dan Phytol. Ekstrak etanol daun simpur air (Dillenia Suffruiticosa L.) berpotensi untuk dikembangkan tanaman obat karena kandungan ekstrak memiliki berbagai aktivitas biologis yang bermanfaat seperti antiinflamasi, antioksidan, antikanker, antidiabetik, antibakteri, dan antijamur
Maternal Body Mass Index as a Determinant of Breast Milk Fat Content in Young Mothers Subandrate Subandrate; Vera Tanzey; Liniyanti D Oswari; Fatmawati Fatmawati; Safyudin Safyudin; Medina Athiah
Jurnal Kebidanan dan Kesehatan Tradisional Jurnal Kebidanan dan Kesehatan Tradisional Volume 11 Number 2 Year 2026
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v11i2.683

Abstract

Background: Fat is a major macronutrient in breast milk, and its concentration varies according to multiple factors, including stage of lactation, time of collection, milk fraction, feeding duration, maternal diet, and maternal body mass index (BMI). Alterations in breast milk fat composition may influence infant growth patterns and long-term metabolic health. This study aimed to examine the association between maternal BMI and the fat content of expressed breast milk. Methods: An analytical observational study with a cross-sectional design was conducted at the Medical Basic Chemistry Laboratory, Faculty of Medicine, Universitas Sriwijaya. Breast milk samples were obtained from 63 breastfeeding mothers in Palembang City, comprising 30 mothers with normal BMI and 33 mothers with obese BMI. Breast milk fat concentration was measured using the glycerol-3-phosphate oxidase–phenol aminophenazone (GPO-PAP) method. Data were analyzed using an independent t-test. Results: The mean fat concentration of breast milk from mothers with normal BMI was 3786.7±743.2 mg/dL, whereas that from mothers with obese BMI was 4339.2±958.0 mg/dL. A statistically significant difference in fat concentration was observed between the two groups (p=0.014). Conclusion: Maternal BMI is significantly associated with the fat content of expressed breast milk, with higher fat concentrations observed in mothers with obese BMI. These findings imply that maternal nutritional status should be considered in lactation counseling and infant feeding practices, particularly to optimize infant growth and metabolic outcomes.
Co-Authors Alderiantama Akhmad Aliah Ramadhani Puteri Ardesy Melizah Kurniati Athiah, Medina Aulia Firdha Tariza Chairil Anwar Dalilah Dazakiah Dita Ardianti Dwi Handayani Dwi Handayani Dzakiyah Dzakiyah Dzakiyah Ella Amalia Ella Amalia, Ella Erizka Rivani Ester G Pansserga Ester Gonzales Panserga Fadiya Fadiya Fadiya Fahira Anindita Fahira Anindita Fahira Aninditia Fidalia Firmansyah Basir Firmansyah Seta Basyir Gita Dwi Prasasty Gita Dwi Prasasty Hafid Syahputra Hana Daini Sabathania Hartati Humairah Binti Huda HUSNUL KHOTIMAH Irfannudin Irfannudin Irfanuddin Irfanuddin Izzah, Puspita Nurul Jayawarsa, A.A. Ketut Kamilah, Rona Hawa Kusumo Hariyadi Kusumo Hariyadi L.O Oswari Liniyanti D Oswari Liniyanti D Oswari Liniyanti D Oswari Liniyanti D. Oswari Liniyati D Oswari Liniyati D Oswari M Athiah M Fakhri Altiyan M Fitra Romadhon M. Ivan Pratama Maharani Natasya Maharani Puspita Sari HS Medina Athiah Mgs Irsan Saleh Mohammad Fazel Iftikhar Syahdafy Muhammad Irsan Saleh Muhammad Rusdi Muhammad Usman Salim Nadia Permata Sari Nadya Nadya Nadya Naomi W Tioline Nita Parisa Nurlutfiyyah Aini Prima Maya Sari Putra Ramadhan Algiffary Irianto Dunda Qherine Bhelqis Qherine Bhelqis RACHMAT HIDAYAT Radiyati Umi Partan Rara Inggarsih Rara Inggarsih Rifka Purnama Sari Rini Yana Rini Yana Rini Yana Rizka Amelia S Sinulingga Sadakata Sinulingga Sadakata Sinulingga Safira Azahra Safyudin Safyudin Safyudin Safyudin Safyudin Safyudin Salmi Salmi Salni Salni Siti Devita Utami Siti Rusdiana Puspa Dewi Sri Hartati Sri Wahyuni Subandrate Susilawati Susilawati Susilawati Syarif Husin Theodorus Theodorus Venny Larasati Vera Tanzey Yundari, Yundari Ziske Maritska