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All Journal Pharmaciana: Jurnal Kefarmasian Naturalis : Jurnal Penelitian Pengelolaan Sumberdaya Alam dan Lingkungan PENA SAINS Jurnal Kimia Riset Journal of Health (JoH) JPM (Jurnal Pemberdayaan Masyarakat) JCES (Journal of Character Education Society) EMBRIO : Jurnal Kebidanan Jurnal Surya Masyarakat JAST : Jurnal Aplikasi Sains dan Teknologi LOYALITAS: Jurnal Pengabdian Kepada Masyarakat Health Information : Jurnal Penelitian Medicra (Journal of Medical Laboratory Science/Technology) Academia Open Madaniya Jurnal Surya Masyarakat Jurnal Pengabdian Masyarakat dalam Kesehatan Medical Scope Journal (MSJ) Jurnal Abdimas Kartika Wijayakusuma Proceedings of The ICECRS Procedia of Social Sciences and Humanities Indonesian Journal of Community Diversity and Engagement IJMI Indonesian Journal Health Science and Medicine
Jamilatur Rohmah
Universitas Muhammadiyah Sidoarjo
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Efektivitas Formulasi Ekstrak Daun Sirih Merah (Piper crocatum) Dengan Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Terhadap Hiperglikemia Serta Histopatologi Pankreas Mencit Handini, Hesti Dwi; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol 1 No 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1477

Abstract

Diabetes mellitus (DM) is metabolism diseases characterized by hyperglycemia and change to the cell histophatology structure of pancreas. Red betel leaves (Piper crocatum) and fragnantpandanleaves (Pandanus amaryllifolius Roxb.) has compound metabolic secondary that efficacious as anantidiabetic. The aims of the study were seek the best extract formulations of red betel leaves (EDSM) and extract of fragnantpandan leaves (EDPW) to lowering blood glucose level, repair the damage of islet langerhans, and comparing the effectiveness with metformin. The research was drafted by post test only control group design using male mencit (Mus musculus) for 31 days. In this research used complete random design with 14 treatment groups, they are normal group, DM group, metfomin group, EDPW 100%group, EDSM 10%+ EDPW 90%group, EDSM 20% + EDPW 80%group, EDSM 30% + EDPW 70% group,EDSM 40% + EDPW 60% group,EDSM 50% + EDPW 50%group,EDSM 60% + EDPW 40% group,EDSM 70% + EDPW 30% group, EDSM 80% + EDPW 20% group, EDSM 90% + EDPW 10% group, and EDSM 100%group. Based on in vivo bioassay showed that metformin have a lot of lowering blood glucose levels (p<0,05) than formulation of EDSM and EDPW but not better in improving islet langerhans tissue damage and treatment DM group with EDSM 50% + EDPW 50% effective lowering blood glucose level comparable with metfomin (p>0,05) and better in improving islet langerhans tissue damage caused by alloxan diabetogenic compound.
Efektivitas Sabun Transparan Antibakteri Ekstrak Etanol Sawi Putih (Brassica Rapa Subspesies. Pekinensis) Dengan Kombinasi Coconut Oil dan Castor Oil Khusniyah, Nurul; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol 2 No 1 (2019): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i1.1488

Abstract

This study aims to determine the best soap formula and to know the effect of addition of chicory extract (Brassica rapa subspecies, pekinensis) in transparent solid soap supply of antibacterial extract of chicory extract (Brassica rapa subspecies, pekinensis) to its effectiveness in Staphylococcus aureus. This research is experimental laboratory. Concentration of chicoryin soap are 0%, 25%, 50%, 75% and 100%. Anti-bacterial effectivenesstest was performed by disc method of transparent antibacterial soap of chicory extract of ethanol (Brassica rapa subspecies, pekinensis) and measured the clear zone. The analysis was performed by Two Way ANOVA test. The results of soap quality assurance standard fulfill quality standard specified by SNI in 1994 that water content test is found in formulation 6 (F6) with 75% concentration equal to 2.109%. The best free alkali test result were found in the formulation 5 (F5) with a 25% concentration of 0.041963, 50% by 0.041966 and 100% by 0.041963. The best free fatty acid test result were found in the formulation of 2 (F2) 50% concentration with free fatty acid level of 0.07852 %. For thebest pH test the conceration of 0%, 25% and 50% with pH yielded 9 and the best foam high yield test was found at 100% concentration. Result of Two Way ANOVA test with variation of extract concentration of chicory ethanol and combination of coconut oil and castor oil obtained p-value = 0.000 <0.05 which states there is real difference. The best test results are in F6 (30.6833 mm). Two Way ANOVA test results showed that transparentsolid soaps of chicory extracts had the best antibacterial effectiveness against Staphylococcus aureus with an inhibitory zone of 30.6833 mm at 100% concentration.
Formulasi dan Evaluasi Sabun Cair Ekstrak Etanol Okra (Abelmochus esculentus) serta Uji Antibakterinya: Formulation and Evaluation of Okra (Abelmochus esculentus) Ethanol Extract Liquid Soap and Its Antibacterial Test Martina, Shofie Fitria; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 2 (2019): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i2.1657

Abstract

Liquid soap is a liquid form that serves to cleanse the skin. The aim of this research are to know the optimization formulation and evaluation of liquid soap extract ethanol okra ( ) and also find the best concentration of okra extract as the inhibitors against Staphylococcus . Experimental laboratory was chosen as the research design. Liquid soap consists of 5 formulations, namely formulation 1, 2, 3, 4, and 5 which consist of 0%, 25%, 50%, 75% and 100% okra concentration. The antibacterial effectiveness was tested by disc method against liquid soap extract ethanol okra ( ) and the clear zone measured. The analysis done with two-way test. The results of the evaluation of liquid soap quality was appropriate with the standard of soap quality established by SNI 1994. The best moisture value found in the formulation of 5 (F5) with 0%form of 3.54%, the best free fatty acid found in formulation 4 (F4) with a concentration of 50% of 0.07135%, the best free alkali concentration was found in formulation 2 (F2) with a 25% concentration of 0.04194%, the best pH value was presented at concentrations of 0%, 25%, and 50% with a value of 9, the best value of foam stability found in Formula 1 (F1) with a 100% concentration of 9.1, the best density (BJ) test found in Formula 4 (F4) with 0% concentration. The result of ANOVA test with variation of ethanol okra concentration obtained p-value = 0.000 &lt;0.05 which states there was a significant difference where liquid soap extract ethanol okra has antibacterial to Staphylococcus . The best inhibitory zone test resulted in formation 5 (F5) of 14.7 mm at 100% concentration.
Heavy Metal Content in Hair at Workers in Gas Station of Sidoarjo City in 2021 Rohmah, Jamilatur; Miranda, Niken Anggita; Marlina, Mariany Lambertine; Fiya, Uus Ufita
Medicra (Journal of Medical Laboratory Science/Technology) Vol 4 No 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1617

Abstract

One of the most dominant workplaces where heavy metal contamination occurs is the Gas Station (SPBU). Gas station workers are at high risk of being exposed to heavy metals while working due to inhaling fuel that evaporates into the air and vehicle fumes due to the behavior of motorists who do not turn off the engine while waiting in line. Determination of the level of heavy metal contamination of Zn, Cu, Pb, Cd, Fe, and Cr was determined through hair clippings using the Atomic Absorbtion Spectrophotometry (AAS) method. The gas stations used in this study are SPBU X and Y in Sidoarjo. This study aims to determine the levels of heavy metals in hair and to determine the relationship between working period, age, smoking habits, and savety with heavy metal levels in gas station workers in Sidoarjo. The type of research used is descriptive cross sectional and analytical method through filling out questionnaires and correlative statistics with SPSS. The results obtained showed that the average levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr at SPBU X were 0.232, respectively; 0.000; 0.003; 0.001; 0.464; and 0.024 mg/g. while the average levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr at SPBU Y were 0.516, respectively; 0.000; 0.007; -0.001; 0.345; and 0.051 mg/g. It can be said that the levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr did not exceed the specified threshold. The results of the statistical test of the correlation between the levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr with years of service, age, smoking habits, and PPE of gas station workers were not significant (p>0.05).
Acute Toxicity Test Against Mice (Mus Musculus) On The Lempuyang Gajah Extract (Zingiber Zerumbet (L.) Roscoe Ex Sm.) With Sgot Sgpt Parameters Sofi Rahayu, Bella; Rohmah, Jamilatur; Rini, Chylen Setiyo; Puspitasari
Medicra (Journal of Medical Laboratory Science/Technology) Vol 7 No 1 (2024): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i1.1656

Abstract

Lempuyang Gajah (Zingiber zerumbet (L.) Roscoe ex Sm) is a medicinal plant that has many benefits in the medicinal industry. Useful as a tonic, external medicine, anti-seizure and appetite enhancer. This study aims to determine the toxicity of the lempuyang gajah. This research uses laboratory experimental methods. The lempuyang gajah plant was obtained in the village of Terungkulon, Krian. The initial stage was the administration of lempuyang gajah extract with various doses of 4000, 5000 and 6000 mg/kg BB orally, consisting of 5 treatment groups. Parameters observed, changes in toxic symptoms, macroscopic examination and parameters of SGOT, SGPT. The results were analyzed using the One Way ANOVA test. The results of the study after giving the extract did not cause death so it was included in the non-toxic category, there were several symptoms such as weakness and seizures. The levels of SGOT, SGPT showed normal average results, statistically there was no effect (p > 0.05). Macroscopic results showed no changes or abnormalities in the liver. So that the ethanol extract of lempuyang gajah can be said to be safe for humans.
Toxicity Test of Ethanol Extract Lempuyang Gajah (Zingiber Zerumbet (L.) Roscoe Ex Sm.) on Bilirubin and Alkaline Phosphatase Levels in Mice (Mus Musculus) Fatmawati, Ririn; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol 5 No 2 (2022): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i2.1657

Abstract

The lempuyang gajah plant (Zingiber zerumbet (L.) Roscoe ex Sm.) is a plant that is widely used as a treatment for desease. The purpose of this study was to determine the toxic effect of the ethanol extract of lempuyang gajah (Zingiber zerumbet (L.) Roscoe ex Sm.) on levels of bilirubin and alkaline phosphatase (ALP) in the liver of mice (Mus musculus). The type of research used is descriptive quantitative with laboratory experimental methods. The mice were divided into 5 groups including normal control, negative control, dose of 4000 kg-1, 5000 kg-1 and 6000 kg-1. then observed the toxic symptoms, macroscopic, levels of bilirubin and alkaline phosphatase. The results of the phytochemical test showed that there were compounds of alkaloids, flavonoids, saponins, phenolics, steroids, triterpenoids and tannins. The results of macroscopic observations showed that the liver was still in a normal condition. The results of the One Way Anova test on bilirubin and alkaline phosphatase levels did not show any significant effect (p>0,05) influence between the normal control group, negative control, doses of 4000 kg-1, 5000 kg-1 and 6000 kg-1, so it can be said that all experimental animals had the same condition.
Analysis Of The Inhibitory Ability Of Spike Attachment Of The Delta Variant Of Sars Cov-2 With Ace2 By The Active Compound In Turmeric (Curcuma longa L.) In Silico Liyaajul, Pratasyah; Mushlih, Miftahul; Rini, Chylen Setiyo; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol 6 No 1 (2023): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i1.1703

Abstract

Turmeric (Curcuma longa L.) is an herbal plant that has many benefits as a treatment, including during the COVID-19 pandemic, one of the mechanisms of inhibition of SARS CoV-2 is to inhibit the attachment of ACE2 with Spike. The binding of the spike protein to the ACE2 receptor will produce conformational changes in the S protein, this study was conducted using an in silico method (computational analysis) which aims to determine the potential efficacy of Turmeric and its effectiveness in inhibiting the Delta variant of SARS CoV-2. The active compound contained in Turmeric (Curcuma longa L. ) obtained from the KNApSAcK database To determine compounds that can have potential and have good effectiveness in inhibition of the Delta Variant of SARS CoV-2, an analysis was carried out by looking at the binding energy and conformation changes that occur at the sticky point in each compound. Three-dimensional structure of SARS CoV-2 Varian Delta downloaded from the Protein Data Bank with PDB code 7V8B. Based on the analysis carried out, it was found that the compound (E)-nuciferoll has the lowest binding energy value of -1212.59 kcal / mol and is located at the initial attachment but cannot change the conformation, but from the sticky point of the compound (E)-nuciferol lies in the initial attachment of RBD-ACE2.
Uji Toksisitas Ekstrak Bunga Turi Putih (Sesbania grandiflora (L.) Pers.) pada Hati Tikus Putih (Rattus novergicus) Salsabila Widya Kirana; Jamilatur Rohmah
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tumbuhan yang melimpah membuat masyarakat memanfaatkannya sebagai bahan pangan, sandang, bahan bangunan, serta obat tradisional. Tumbuhan turi memiliki kandungan senyawa fenolik, tannin, flavonoid, karbohidrat, protein, alkaloid dan glikosida. Tujuan dari penelitian ini adalah untuk mengetahui toksisitas akut ekstrak etanol turi putih terhadap gejala toksik, pengamatan makroskopis organ hati dan pengukuran kadar bilirubin dan alkalin fosfatase . Jenis penelitian ini merupakan penelitian eksperimental laboratorik menggunakan rancangan penelitian Post Test Only Control Group Design. Tikus terbagi menjadi 4 kelompok yaitu kontrol normal, dosis 10.000, 15.000 dan 20.000 mg/kgBB, kemudian mengamati gejala toksik makroskopis, kadar bilirubin dan alkalin fosfatase. Hasil uji fitokimia menunjukkan bahwa bunga turi mengandung senyawa alkaloid, saponin, tannin, steroid dan triterpenoid. Pada pengamatan makroskopis organ hati menunjukkan dalam kondisi normal. Berdasarkan uji One Way Annova pada kadar bilirubin dan alkalin fosfatase menunjukkan hasil kadar bilirubin p<0,05 (0,000) dan kadar alkalin fosfatase p<0,05 (0,004). Dapat disimpulkan bahwa dosis penggunaan ekstrak etanol bunga turi putih dengan variasi 10.000, 15.000 dan 20.000 mg/kgBB menunjukkan adanya toksisitas akut ekstrak bunga turi putih berdasarkan gejala toksik yang ditimbulkan namun belum sampai menimbulkan kematian pada hewan coba tetapi menimbulkan efek toksik terhadap kadar bilirubin dan alkalin fosfatase pada organ hati tikus.
Training of Visual Media Based on Natural Materials as a Learning Facility for Independent Learning at Sdn Kupang 4 Sidoarjo: Pelatihan Media Visual Berbasis Bahan Alam Sebagai Fasilitas Pembelajaran Merdeka Belajar di SDN Kupang 4 Sidoarjo Wati, Tri Linggo; Wakhidah, Kemil; Rohmah, Jamilatur; Firdaus, Firyalita Sarah; Putra, Moh. Faris Yudiana
Procedia of Social Sciences and Humanities Vol. 3 (2022): Proceedings of the 1st SENARA 2022
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/pssh.v3i.206

Abstract

The purpose of this community service activity is to provide training in making visual media based on natural materials for teachers at SDN Kupang 4 Sidoarjo. The problem faced by partners is the lack of mastery of the element of providing facilities in the learning process, namely not providing media at every learning time. While the SDN Kupang 4 Sidoarjo school is rich in natural potential, because it is located in a pond area with materials that are easy to use as learning media that can be used as learning materials in the teaching and learning process. The methods of implementing these community service activities are: conducting a needs analysis by making observations regarding the problems that exist with partners to be immediately assisted in solving problems, then determining the objectives of the training, conducting education, training, and monitoring and evaluation of the application of media in the learning process. obtained after receiving training in visual media based on natural materials, teachers and students produce a learning media by adjusting the existing theme, then the teacher applies the media in learning activities. So that learning is no longer monotonous but looks fun and meaningful because students become interactive learning through the media that is applied.
Cadre Training in Detecting Toddler Development in Ketimang Village, Wonoayu District: Pelatihanan Kader Dalam Deteksi Perkembangan Anak Balita Di Desa Ketimang Kecamatan Wonoayu Cholifah, Siti; Purwanti, Yanik Purwanti; Rohmah, Jamilatur; Aini, Latifatul
Procedia of Social Sciences and Humanities Vol. 3 (2022): Proceedings of the 1st SENARA 2022
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/pssh.v3i.223

Abstract

A child has the characteristics of growing and developing. Children's growth can be seen from the increase in weight and height, while development can be monitored from fine motor skills, gross motor skills, speech and language skills, socialization and independence of children. Early detection of development is very important so that babies and toddlers who experience delays can immediately get treatment and stimulation. The purpose of community service activities is to increase the knowledge and skills of cadres to detect the development of infants and toddlers. Based on the results of surveys and interviews in Ketimang village, routine posyandu activities are weighed for monitoring child growth, but this has not been accompanied by development monitoring by cadres, due to lack of knowledge of cadres about detecting child development, besides the duties and activities of village midwives are very tight so there is no opportunity. to train cadres and carry out routine development detection at posyandu. The solution offered is to conduct cadre training to detect child development according to the agreement carried out on February 12, 2022 at the home of the posyandu cadre head. The implementation method starts with conducting surveys, preparing the Developmental Pre-Screening Questionnaire (KPSP) media, and implementing training and evaluating activities. The results of the activity, this community service was attended by 17 posyandu cadres, before training 10 cadres (58.9%) had less knowledge about developmental detection, after training they became well-informed and 7 cadres (41.1%) had good knowledge after training they became well-informed. very good knowledge. This shows that there is an increase in the knowledge and skills of cadres in detecting the development of infants under five.
Co-Authors Achmad Noerkhaerin Putra Aini, Latifatul Andika Aliviameita Anwar, Najih Arini Siti Wahyuningsih Aziza, Vidayatul Chylen Setiyo Rini Devi Arvindani Masyitha Eni Fariyatul Fahyuni Fadilah, Fitrian Nur FATMAWATI, RIRIN Firdaus, Firyalita Sarah Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fitrian Desi Prameswari Fiya, Uus Ufita Furqonati, Lili Galuh Ratmana Hanum Handini, Hesti Dwi Hidayat, Mokhamad Amirul Ida Agustini Saidi Karlia Hedit Tiana Khusniyah, Nurul Liyaajul, Pratasyah Makrufah, Makrufah Margareta, Frida Amelia Marlina, Mariany Lambertine Martina, Shofie Fitria Miftahul Mushlih Miranda, Niken Anggita Mukarromah, Rizka Aisya Novitasari, Fia NUR EFENDI NURUL AZIZAH Nurul Azizah Paramitha Amelia Kusumawardani Purwanti, Yanik Purwanti Puspitasari Puspitasari Putra, Moh. Faris Yudiana Rafhani Rosyidah Rini , Chylen Setiyo Rini, Chylen S. Rofidah, Luthfiyah Salsabila Widya Kirana Siroj, Muhammad Said Agil Siti Cholifah SITI CHOLIFAH Sofi Rahayu, Bella Tri Chahyani Rahmawati Putri Tri Linggo Wati Vanda Rezania Wakhidah, Kemil Widyaningrum, Leni Yuroh Yuli Astutik Zulfida Ainindiyah Putri Purwanto Zurrotul Ilmiyah