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All Journal Jurnal Sain Veteriner Jurnal Veteriner Jurnal Sain Peternakan Indonesia Jurnal Pengabdian Kepada Masyarakat Sakai Sambayan Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Aquasains : Jurnal Ilmu Perikanan dan Sumberdaya Perairan JURNAL ILMIAH PETERNAKAN TERPADU Jurnal Ekonomi Pembangunan Wahana Peternakan Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Jurnal Riset dan Inovasi Peternakan (Journal of Research and Innovation of Animals) Jurnal Kedokteran Hewan Buletin Pengabdian Jurnal Pengabdian Fakultas Pertanian Universitas Lampung
Ratna Ermawati
Study Program Of Animal Husbandry, Department Of Animal Husbandry, Faculty Of Agriculture, University Of Lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Journal : Jurnal Sain Veteriner

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Effectiveness of Sambiloto (Andrographis paniculata) Supplementation on Antibody Titers of Newcastle Disease, Avian Influenza and Infectious Bursal Disease in Broilers Hartono, Madi; Sirat, Muhammad Mirandy Pratama; Santosa, Purnama Edy; Ermawati, Ratna
Jurnal Sain Veteriner Vol 42, No 3 (2024): Desember
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.69829

Abstract

Newcastle Disease, Avian Influenza and Infectious Bursal Disease are three important broiler diseases with high morbidity and mortality that can increase broiler antibody titers. The aims of this study were to determine the effect and the best dose of immunomodulatory supplementation of Sambiloto (Andrographis paniculata) liquid extract by increasing the antibody titer of Newcastle Disease, Avian Influenza and Infectious Bursal Disease of broilers. The study was conducted for 30 days in the Karang Anyar broiler farm unit, Jati Agung District, South Lampung Regency, Lampung Province, experimentally five treatments and five repetitions for each treatment. Each repetition used five broilers. Five treatments with different doses, namely drinking water without liquid extract of Andrographis paniculata (P0); drinking water with liquid extract of A. paniculata 3 mg/kg BW (P1); 6 mg/kg BW (P2); 12 mg/kg BW (P3); (24 mg/kg BW (P4) 31-day-old broiler blood serum was obtained from the brachial vein using a 3 mL disposable syringe. Testing ND and AI antibody titers with HI test and IBD antibody titer with indirect ELISA test at MediLab Laboratory Antibody titer data in tabulation and analyzed descriptively. The content of andrographolide and flavonoids are thought to act as immunostimulants for specific and non-specific immune functions through the production of NK cells, macrophages, cytokine induction, IL-2 production, and lymphocyte proliferation. The conclusions of this study were supplementation of Sambiloto (Andrographis paniculata) liquid extract at a dose of 6 mg/kg BW in broiler drinking water could increase antibody titers against Newcastle Disease and Infectious Bursal Disease and at a dose of 24 mg/kg BW in broiler drinking water could increase antibody titres against Avian Influenza.
Co-Authors Abimanyu Prastyo Ardiansyah Adek Rayhan Regisa Aksal Alfarizki Alfarizki, Aksal Alfaruq, Fahmi Fadhilah Ali Husni Arif Qisthon Aris Haryanto Ayu Fitriani Ayu Lidyana Ayu Lidyana Bayu Hadi Setya Irawan Budiyanto, Ferly Rahmat Charles Rangga Tabbu Cici Hardiyanti Dakhlan, Akhmad Deny Sapto Chondro Utomo Desmawan, Deris Dhani, Akbar Rahmat Dian Septinova Dini Wahyu Yudianingtyas Emi Maimunah Erwanto Erwanto Erwanto Fajar Shodiq Permata Fani Setiawan Farida Fathul Fatmawati, Siti Tika Fauzi, Teo Achmad Fina Arzakiyah Fitria Tsani Farda Fitria Tsani Farda Guntur Januar Yudhistira Hanafi, Riyan Hanip Rangga Saputra Hardiyanti, Cici Hari, Putu Gaura Hermilinda Parera Hizkia, Ezra I Kadek Dwi Agus Candra Wijaya Ilhamsyah, Alifudin Imam Widodo Imam Widodo Juandita, Karina Natasya Karina Natasya Juandita Kusuma, Yosea Talenta Lidyana, Ayu Liman Liman Liman Liman Liman, Liman Madi Hartono Madi Hartono Madi Hartono Madi Hartono Madi Hartono Mahfud Rivai Medania Purwaningrum Mia Widowati Michael Haryadi Wibowo Muhammad Mirandy Pratama Sirat Muhammad Mirandy Pratama Sirat Muhiddin Sirat Muhtarudin Muhtarudin mulya, arif eka Nisak, Rohmatin Nur Aini Nur Aini Pramana, Sandika Purnama Edy Santosa Purnama Edy Santosa Purnama Edy Santosa Purnama Edy Santosa Purnama Edy Santosa Purnama Edy Santosa Purnama Edy Santosa Purnama Edy Santosa Rais, Ambarwati Mirna Ramadanti, Andin Hairunnisa Rivai, Mahfud Riyan Hanafi Riyan Hanafi Rohmatin Nisak Rr Riyanti, Rr S Siswanto Safira, Auliya Sagala, Yollanda Natalia Sandika Pramana Sani, Darwan Sanjaya, Purba Setio, Slamet Shaleh, Shofyan Sherlina Widya Rahma Sherlina Widya Rahma Sirat, Muhiddin Siswanto Siswanto Siswanto Siswanto Siswanto Siswanto Siti Tika Fatmawati Siti Tika Fatmawati Slamet Setio Sri Suharyati Surmini Surmini Surmini Surmini Surmini, Surmini Syahrio Tantalo Syahrio Tantalo Syahrio Tantalo Teo Achmad Fauzan Teo Achmad Fauzi Teo Achmad Fauzi Utami Syifana Widyastuti Veronica Wanniatie Widowati, Mia Yollanda Natalia Sagala Yudhistira, Guntur Januar Yuliana, Darma Zulvina Afrianti