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PEMANFAATAN CAMPURAN ARANG AKTIF KAYU Muntingia calabura L. DAN BAKTERI Escherichia coli PADA PENGOLAHAN LIMBAH KROMIUM INDUSTRI ELEKTROPLATING Endang Sri Lestari; Yusuf Sudo Hadi; Gustan Pari
Jurnal Penelitian Hasil Hutan Vol. 37 No. 2 (2019): Jurnal Penelitian Hasil Hutan
Publisher : BRIN Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/jphh.2019.37.2.105-122

Abstract

The presence of heavy metal chromium wasted from electroplating industry could harm human health, such as posing cancer and kidney failure. In order to overcome this problem, the effluent treatment was carried out by means of adsorption of chromium using wood activated charcoal. This paper aims to study the benefits of Muntingia calabura wood activated charcoal, especially seeking its optimal conditions for adsorption test and the ability of Escherichia coli bacteria to turn out chromium (VI) biodegradation into chromium (III) on chromium waste of electroplating industry. Wooden charcoal was produced after heating wood at 500°C for an hour and it was activated using hot water vapor at 800°C for 70 minutes and pressure 120 mBar. The adsorption test was conducted in variation of 20−100 mg/L of adsorbate initial concentration, contact time 45−105 minutes, and stirring speed of 100−300 rpm. Biodegradation test was conducted using Escherichia coli bacteria which was incubated in nutrient broth containing of adsorption waste. Results showed that the optimal conditions of the adsorption test was recorded at the initial concentration of 70 mg/L, 150 rpm stirring speed, 75 minutes contact time, and 86.7% adsorption effectivity. The biodegradation effectivity for turning chromium (VI) into chromium (III) was recorded at 98.6%.
Modulation of Inflammatory and Regenerative Pathways by Channa striata Extract in End-to-End Anastomotic Wound Repair: A Systematic Review Faizurrahman Andi Kusuma; Sigit Adi Prasetyo; Endang Sri Lestari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1264

Abstract

Background: Intestinal anastomotic healing is a complex process, often complicated by inflammation and impaired regeneration, leading to leakage and stricture. Channa striata (snakehead fish) extract, traditionally used for wound healing, possesses bioactive compounds with potential anti-inflammatory and regenerative properties. This systematic review aimed to critically appraise the in vivo evidence for the effects of Channa striata extract on inflammatory and regenerative pathways in end-to-end anastomotic wound repair. Methods: A comprehensive search of PubMed/MEDLINE, Scopus, Web of Science, Embase, and Cochrane Library databases was conducted for studies published between 2013 and 2024. Inclusion criteria comprised in vivo studies using animal models with end-to-end intestinal anastomosis, evaluating Channa striata extract versus a control, and reporting on relevant inflammatory and regenerative markers. Data extraction and risk of bias assessment (using SYRCLE's tool) were performed. Results: Seven studies met the inclusion criteria. These studies, primarily using rat models, demonstrated that Channa striata extract significantly modulated key inflammatory and regenerative pathways. Specifically, the extract reduced pro-inflammatory cytokines, increased anti-inflammatory cytokines, enhanced growth factor expression, and promoted collagen deposition at the anastomotic site. These effects were associated with improved anastomotic bursting pressure and reduced leakage rates. Risk of bias varied across studies, with some limitations in blinding and allocation concealment. Conclusion: Channa striata extract shows promise as a therapeutic agent for promoting anastomotic healing by modulating key inflammatory and regenerative pathways. However, further high-quality, standardized studies are needed to confirm these findings, elucidate precise mechanisms, and optimize extract formulation and dosage before clinical translation.