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All Journal Jurnal Ilmiah Farmasi JBIO: jurnal biosains (the journal of biosciences) JURNAL FARMASIMED (JFM) Best Journal (Biology Education, Sains and Technology) GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Jurnal Health Sains FORTE JOURNAL International Conference on Sciences Development and Technology PCJN Pharmaceutical and Clinical Journal of Nusantara Herbal Medicine Journal Jurnal ABDIMAS MUTIARA Borneo Journal of Pharmacy
Asfianti, Vivi
Institut Kesehatan Medistra Lubuk Pakam
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other

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HUBUNGAN TINGKAT PENGETAHUAN DAN PERSEPSI WANITA DI DESA LANCOK-LANCOK KECAMATAN KUALA KABUPATEN BIREUEN TERHADAP BAHAYA KRIM PEMUTIH WAJAH Eva Diansari Marbun; Alfi Sapitri; Vivi Asfianti
FORTE JOURNAL Vol 3 No 1 (2023): Edisi Januari 2023
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v3i1.492

Abstract

Mengingat banyaknya iklan produk krim pemutih di televisi, belum lagi di media cetak memang sangat menggiurkan. Apapun rela mereka lakukan untuk tampil lebih cantik dengan kulit wajah yang putih bersih. Bahkan harga bukan masalah bagi mereka. Tetapi, tanpa mereka sadari banyak efek yang ditimbulkan oleh produk krim pemutih yang mengandung zat-zat kimia berbahaya. Tujuan penelitian ini yaitu untuk mengetahui Hubungan Tingkat Pengetahuan dan Persepsi Wanita di Desa Lancok-Lancok Kecamatan Kuala Kabupaten Bireuen Terhadap Bahaya Krim Pemutih Wajah dan untuk mengetahui Hubungan Tingkat Pengetahuan dan Persepsi Wanita di Desa Lancok-Lancok Kecamatan Kuala Kabupaten Bireuen Terhadap Bahaya Krim Pemutih Wajah.  Metode penelitian ini merupakan penelitian deskriptif untuk mengetahui tingkat pengetahuan dan persepsi wanita di Desa Lancok-Lancok Kecamatan Kuala Kabupaten Bireuen Terhadap Bahaya Krim Pemutih Wajah. Alat ukur yang digunakan adalah kuesioner, Sampel dalam penelitian ini diambil dengan menggunakan teknik purposive sampling, yaitu sebanyak 36 orang. Analisa data menggunakan uji Chi-square. Hasil dari penelitian hubungan tingkat pengetahuan dan persepsi Wanita di Desa Lancok-Lancok Kecamatan Kuala Kabupaten Bireuen terhadap bahaya krim pemutih wajah meunjukkan pengetahuan diperoleh hasil baik (2.8%) cukup (27.8%) dan kurang (69.4%). Persepsi diperoleh hasil sangat baik (11.1%) baik (75.0%) dan cukup (13.9%). Adanya hubungan tingkat pengetahuan dan persepsi wanita di Desa Lancok-Lancok Kecamatan Kuala Kabupaten Bireuen diperoleh hasil dengan nilai p value sebesar 0,018< 0,05.
EVALUASI FORMULASI SEDIAAN SALEP DARI EKSTRAK UMBI PORANG (Amorphophallus meulleri Blume) Alfi Sapitri; Eva Diansari Marbun; Vivi Asfianti; Retnita Ernayani Lubis
FORTE JOURNAL Vol 4 No 1 (2024): Edisi Januari 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v4i1.692

Abstract

Manfaat umbi porang (Amorphophallus meulleri Blume) sangat bervariasi yaitu untuk meningkatkan imunitas tubuh, penyumbang serat yang baik, sebagai prebiotik dan mampu membantu penyerapan kalsium tubuh dengan baik. Oleh karena itu beragam pengolahan porang menjadi pangan fungsional bahkan obat-obatan. Umbi porang umumnya tumbuh secara liar dan sering dianggap gulma, selain itu porang mengandung kalium oksalat yang tinggi. Kalium oksalat dapat menyebabkan batu ginjal dan berbagai gangguan kesehatan tubuh. Oleh karena itu harus dihilangkan terlebih dahulu zat tersebut sebelum dikonsumsi maupun diolah menjadi suatu olahan pangan. Tujuan penelitian ini untuk mengetahui formulasi sediaan salep basis hidrokarbon dan mudah dicuci yang paling efektif dengan uji sifat fisiknya. Penelitian  ini  merupakan  eksperimental dan dilakukan di laboratorium Fakultas Farmasi dan Ilmu Kesehatan, Universitas Sari Mutiara Indonesia, pembuatan tepung umbi porang dikarakterisasi dan diskrining fitokimia kemudian dibuat formulasi salep salep basis hidrokarbon dan mudah dicuci dengan konsentrasi 5%, 10 % dan 15%. Sediaan salep salep basis hidrokarbon dan mudah dicuci akan dilakukan pengujiannya baik dari homogenitas, Uji pH, Uji Iritasi, daya lekat dan daya sebar. Hasil penelitian menunjukkan bahwa salep hidrokarbon salep basis hidrokarbon dan mudah dicuci dapat memberikan hasil homogen yang tidak ada gumpalan pada sediaan salep, uji pH memberikan hasil nilai pH asam yaitu pH 5 , uji iritasi yang dicoba pada relawan tidak memberikan efek iritasi pada kulit, daya lekat yang baik serta daya sebar mampu menyebar dengan mudah ditempat pemberian, tanpa menggunakan tekanan. Kesimpulan dari penelitian ini adalah bahwa semua parameter evaluasi salep memenuhi persyaratan.
Stunting Prevention Movement Through Fortification of Moringa Leaves and Mung Bean Flour in Cookies as PMT (Supplementary Feeding) For Toddlers in Medan Sunggal District Denny Satria; Aminah Dalimunthe; Hafid Syahputra; Vivi Asfianti; Syukur Berkat Waruwu
GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2025): GANDRUNG: Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Olahraga dan Kesehatan, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/gandrung.v6i2.4654

Abstract

Stunting is a serious problem and is also a major nutritional problem. The problem of stunting has a quite serious impact. It can be short-term related to morbidity and mortality in infants and toddlers, medium-term related to low intellectual and cognitive ability, and long-term related to the quality of human resources and degenerative disease problems in adulthood. The average prevalence of stunting in Indonesia from 2015 to 2017 was 31.4%, far above the WHO limit of 20%. The government with Presidential Decree No. 42/2013 has established a national movement for the first 1000 days of life to improve the nutritional status of toddlers as an effort to handle stunting in Indonesia. Because of the mothers' lack of knowledge about stunting, we were moved to do community service in Medan Sunggal District. Based on this thought, this community service activity is carried out to educate women (community) about the importance of good and correct food processing regarding nutrition/nutrition intake for toddlers by making mothers health cadres in the family in the application of functional food processing from natural ingredients such as moringa leaves and mung beans for stunting prevention in Medan Sunggal District.
Aktivitas Antibakteri Ekstrak Etanol Daun Jengkol (Archidendron pauciflorum Benth.) Terhadap Bakteri Staphylococcus epidermidis dan Pseudomonas aeruginosa Arisetya, Dian; Sapitri, Alfi; Asfianti, Vivi; Lubis, Retnita Ernayani
Herbal Medicine Journal Vol 8 No 2 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i2.162

Abstract

Archidendron pociflorum benth is a nutritious plant that is used as a traditional medicine that is often used by society. Secondary metabolic compounds contained in archidendron pociflorum leaves are alkaloids, flavonoids, tannins and saponin. The purpose of this research is to know the antibacterial activity of the extract of archidendron pociflorum leaf ethanol from the Staphylococcus epidermidis and Pseudomonas areuginosa bacteria. Research conducted experimentally including the collection and processing of archidendron pociflorum leaves. The powder simplisia leaves archidendron pociflorum then be done characteristic and macerated using ethanol 96%. Further extracts of archidendron pociflorum leaf ethanol in the phytochemical screening and carried out test antibacterial activity against Staphylococcus epidermidis and pseudomonas areuginosa bacteria use the diffusion method to make it with disc paper. Results characteristic simplisia of archidendron pociflorum leaves obtained water content of 8.1%, water soluble sari content of 9.49%, soluble pollen content of 7.61%, total ash content 3.80%, ash content of insoluble acid 14.67%. Scining extracts of archidendron pociflorum leaves and simplisia indicate the presence of alkaloid, tannins, saponin, flavonoids. The test results of antibacterial activity indicate that the leaf ethanol extract of the staphylococcus epidermidis bacteria with a concentration of 80%, 60%, 40%, 20% respectively had an obstacle zone of 13.6 mm, 12.3 mm, 11, 4mm and 9.7 mm. While in bacteria pseudomonas areuginosa with a concentration of 80%, 60%, 40%, 20% respectively has a inhibitory zone of 14.3 mm, 13.1 mm, 11.2 mm and 10.3 mm. Archidendron pociflorum leaf ethanol extract has been effective against antibacterial activity with a concentration of 80% against bacteria staphylococcus epidermidis and pseudomonas aureginosa.
Development of Community Creativity and Skills Potential in Supporting the Drug-Prone Area Eradication Program in Tualang Village Serdang Bedagai Regency Fadli, Ahmad; Amin Hou; Denny Satria; Vivi Asfianti; Syukur Berkat Waruwu
GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 1 (2025): GANDRUNG: Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Olahraga dan Kesehatan, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/gandrung.v6i1.4521

Abstract

The problem of drug use has now become a pandemic that occurs in almost all regions in our country, prone to drugs where drug use is not only consumed by adults but also adolescents and children also become victims. As for the spread, it no longer focuses on big cities but has penetrated the villages, which are massive even with many casualties. This condition of vulnerability must be addressed immediately considering the severe impact that spreads such as social problems and increasing crime. Of course, the program to minimize this impact must be carried out immediately, in line with that, the proposal for community service activities has prepared a program that will provide solutions to these conditions, including: 1. Conducting Anti-Drug Socialization/Counseling training.2, Providing technical training on small business skills in making noodles, 3 Small and Medium Business management training
Functional Food Processing Application as PMT (Providing Additional Food) for BADUTA in the Program to Support the Movement to Prevent Stunting in Medan Deli District Vivi Asfianti; Denny Satria; Ahmad Hafizullah Ritonga; Ahmad Fadli; Alfi Sapitri
GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 1 (2024): GANDRUNG: Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Olahraga dan Kesehatan, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/gandrung.v5i1.3216

Abstract

Stunting is a form of growth failure due to the accumulation of inadequate nutrition that lasts for a long time starting from pregnancy until the age of 24 months, characterized by body length or height being below standard, based on the PB/U or TB/U index, the results of these measurements are at the threshold < -2 SD, =-3 SD (short) and <-3 SD (very short). Based on WHO data (2020), the prevalence of stunting in children under five in the world is 149.2 million or around 22%, the national prevalence of stunting in 2022 is 21.6%, the prevalence of stunting in North Sumatra (January 2023) reaches 21.1%, ranked 17th from 34 provinces with the highest number of stunted children in Indonesia. The prevalence of stunting in Medan City (as of April 1 2023) is 298 children under five. Data obtained from the Medan Deli District Family Planning Coordinator, currently there are 28 stunted toddlers and 30 stunted toddlers, of the 28 stunted toddlers, 1 toddler has 'graduated' from stunting. The aim of this service is to apply functional food processing as PMT (Supplemental Food Provision) for BADUTA as an effort to support the Stunting Prevention Movement Program in accordance with PERPRES (2021) No. 72. In the outreach activities, pretest and posttest evaluation activities were carried out to determine the level of knowledge of participants regarding the provision of additional protein-rich functional food (PMT) in the form of cereal cookies to stunted toddlers and those at risk of stunting by providing simple choice questions that they had to answer. The results of the service obtained are functional stunting food products in the form of cookies containing porang flour and moringa
SOSIALISASI PEMBUATAN SEDIAAN GEL EKSTRAK ETANOL DAUN BANGUN-BANGUN (Pleotranthus ambonicus (Lour.) Spreng) SEBAGAI ANTIBAKTERI Asfianti, Vivi; Purba, Hana Ike Dameira; Sitorus, Binsar
Jurnal Abdimas Mutiara Vol. 1 No. 1 (2020): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibakteri merupakan zat yang dapat mengganggu pertumbuhan bahkan mematikan bakteri dengan cara mengganggu metabolisme mikroba yang merugikan manusia. Tanaman Bangun-bangun (Plectranthus amboinicus (Lour.) Spreng) diketahui merupakan salah satu tanaman herbal yang ada di Indonesia. Penggunaan daun bangun-bangun sering digunakan sebagai peningkat ASI oleh masyakarat. Daun bangun-bangun mengandung senyawa metabolit sekunder yaitu, flavonoida, polifenol dan minyak atsiri. Senyawa-senyawa tersebut secara umum berkhasiat sebagai antibakteri. Tujuan dari sosialisasi ini untuk memberikan informasi kepada masyarakat kelurahan beruam, kecamatan kuala, kabupaten langkat mengenai pembuatan sediaan gel ekstrak etanol daun bangun-bangun sebagai antibakteri. Hasil Kegiatan pelaksanaan ini memberikan edukasi dan sosialisasi tentang pembuatan sediaan gel ekstrak etanol daun bangun-bangun sebagai antibakteri. Kesimpulan dari kegiatan sosialisasi ini dapat terlaksana sesuai pelaksanaan dan rencana, medapatkan sambutan baik dari pemerintah dan masyarakat setempat dan masyarakat sekiranya mendappatkan informasi serta pngetahuan.
Antibacterial Activity of Ethyl Acetate Extract of Beetroot (Beta vulgaris L.) against Methicillin-Resistant Staphylococcus aureus and Streptococcus mutans Hariman, Hariman; Maimunah, Siti; Marbun, Eva Diansari; Asfianti, Vivi
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 4 No. 01 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i03.143

Abstract

Beetroot (Beta vulgaris L.) is a cultivated plant with medicinal properties, containing bioactive compounds such as flavonoids, tannins, and saponins that are known to exhibit antibacterial activity. Methicillin-Resistant Staphylococcus aureus (MRSA) and Streptococcus mutans pose significant clinical challenges due to antibiotic resistance and their association with nosocomial infections and dental caries, respectively. This study aimed to evaluate the antibacterial activity of ethyl acetate extract of beetroot against MRSA (ATCC 43300) and Streptococcus mutans (ATCC 25175) using the disc diffusion method. Simplicia characterization revealed a water content of 13.15%, water-soluble extract of 42.5%, ethanol-soluble extract of 44.8%, total ash of 12.56%, and acid-insoluble ash of 1.81%. Phytochemical screening confirmed the presence of alkaloids, flavonoids, terpenoids, steroids, saponins, and tannins. Antibacterial testing at concentrations of 125, 250, and 500 mg/ml showed inhibition zones of 8.3, 8.7, and 11.5 mm against MRSA, and 7.5, 8.4, and 10.3 mm against S. mutans, respectively. The minimum inhibitory concentration (MIC) was determined to be 125 mg/ml for both bacterial strains. These findings suggest that the ethyl acetate extract of beetroot possesses promising antibacterial activity ranging from moderate to strong category.
FORMULASI SEDIAAN KRIM TABIR SURYA EKSTRAK ETANOL DAUN PECUT KUDA (Stachytarpheta jamaicensis L) DAN UJI Surya Protection Factor (SPF) SECARA IN VITRO Marbun, Eva Diansari; Sapitri, Alfi; Sianipar, Artha Yuliana; Asfianti, Vivi
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 1 (2025): Juni 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i1.10697

Abstract

Tabir surya merupakan suatu bahan topikal yang berfungsi untuk mengurangi dampak radiasi yang di sebabkan oleh sinar UV. Daun pecut kuda (Stachytarpetha jamaicensis L) merupakan tanaman yang banyak di manfaatkan untuk menjaga kesehatan dan sebagai obat tradisisonal. Tujuan dari penelitian ini Untuk mengetahui ekstrak etanol daun pecut kuda (Stachytarpheta jamaicensis L) dapat di formulasikan menjadi sediaan krim tabir surya, dan Untuk mengetahui nilai SPF (Sun Protector Factor) dari ekstrak daun pecut kuda (Stachytarpheta jamaicensis L). Metode peneleitian ini menggunakan metode eksperimental atau percobaan yang di mulai dari pengambilan sampel, sortasi basah, pengeringan, sortasi kering, penimbangan, penghalusan simplisia, perkolasi, dan rotary hingga menjadi ekstrak. Hasil penelitian uji mutu fisik krim tabir surya ekstrak etanol daun pecut kuda dengan konsetrasi 1%,2%,3% berbentuk setengah padat, warna cokelat, dan berbau khas rossae. Homogenitas pada sediaan yaitu homogen, Uji pH pada ketiga konsentrasi yaitu 5,9, 6,3, 6,5. Uji tipe krim menunjukkan ketiga konsentrasi yang termasuk tipe m/a. Uji daya lekat pada ketiga konsentrasi memenuhi syarat uji yaitu lebih dari 1 detik. Uji daya sebar pada ketiga konsentrasi memenuhi syarat uji yaitu 5-7cm. Uji iritasi pada ketiga konsentrasi tidak memberikan efek iritasi pada kulit. Uji Viskositas pada ketiga konsentrasi rata-rata 14300. Uji hiodonik dapat di simpulkan bahwa sedian yang paling di sukai panelis adalah konsentrasi 2%. Dan uji nili SPF di dapat hasil F1:1,97(minimal, F2:3,25(minimal), F3:6,41(Ekstra). Kesimpulan pana penelitian ini adalah formulasi ekstrak etanol daun pecut kuda(Stachytarpetha jamaicenis L) dapat di formulasikan sebagai sediaan tabir surya, dan ekstrak etanol daun pecut kuda (Stachytarpetha jamaicensis L) mempunyai nilai SPF(Surya Protection Factor).
Effect of Tocotrienol Rich Fraction (TRF) Administration on Blood Glucose and Cholesterol in Streptozotocin Induced and High Fat Diet Rats Irene Simangunsong; Dewi Pertiwi; Aminah Dalimunthe; Vivi Asfianti
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/139epr61

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder with a continuously increasing global prevalence and remains a major health problem, characterized by hyperglycemia and dyslipidemia, including elevated Low Density Lipoprotein (LDL) and decreased High Density Lipoprotein (HDL) levels. This study aimed to evaluate the effect of tocotrienol rich fraction administration on blood glucose levels and lipid profile in rats induced with streptozotocin and a high fat diet. The study used 24 white rats divided into six groups: a negative control group, a positive control group treated with glibenclamide, and four treatment groups receiving tocotrienol rich fraction at doses of 50, 100, 200, and 400 mg/kg body weight. The measured parameters included blood glucose, HDL, and LDL levels. The results show that tocotrienol rich fraction significantly reduces blood glucose levels and improves the lipid profile compared to the negative control group. The highest dose demonstrates the most optimal effect and approaches that of the positive control. Tocotrienol rich fraction increases HDL levels and decreases LDL levels in a dose dependent manner. These findings indicate that tocotrienol rich fraction significantly lowers blood glucose levels and improves lipid profile in streptozotocin induced and high fat diet rats in a dose dependent manner. Therefore, tocotrienol rich fraction has potential as an alternative therapeutic agent for diabetes mellitus with dyslipidemia.
Co-Authors Ahmad Fadli Alfi Safitri Alfi Sapitri Alfi Sapitri Alfi Sapitri Alfi Syahfitri Amin Hou Aminah Dalimunthe Aminah Dalimunthe Antonius Wilson Sembiring Artha Yuliana Sianipar Daely, Ruth Christiani N Denny Satria Dewi Pertiwi Dian Arisetya Dian Arisetya, Dian Eva Diansari Marbun Eva Diansari Marbun Eva Diansari Marbun Grace Anastasia Br. Ginting Grace Anastasia Ginting Hafid Syahputra Harianja, Ester Saripati Hariman, Hariman Iksen, Iksen Irene Simangunsong Kasta Gurning Marbun, Eva Diansari Marbun, Eva Diansari Maya Amelia Sinaga Modesta Harmoni Br. Tarigan Modesta Harmoni Tarigan Owen De Pinto Simanjuntak Prima Jaya Nazara Purba, Hana Ike Dameira Purba, Sri Dearmaita Retnita Ernayani Lubis Sapitri*, Alfi Sapitri, Alfi Sapitri, Alfi Sianipar, Artha Yuliana Siti Maimunah Sitorus, Binsar Sondang Purba Syahrina Syahrina Syukur Berkat Waruwu Ulfayani Mayasari Zuhairiah Nasution, Zuhairiah