Claim Missing Document
Check
Articles

Found 8 Documents
Search
Journal : Pharmaceutical Reports

The Effect of Heating on Ascorbic Acid Levels of Brassica oleracea L. Determined by UV-Visible Spectrophotometry Muzakkir Baits; Riski Mentari Jahri; Asriani Suhaenah; Aminah Aminah; Tadjuddin Naid; Muammar Fawwaz
Pharmaceutical Reports Vol 1, No 1 (2022): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.042 KB) | DOI: 10.33096/pharm rep.v1i1.156

Abstract

Vitamin C is one of the nutrients that act as antioxidants derived from fruits and green vegetables, such as the broccoli (Brassica oleracea L.). This study aims to warming influence on levels of vitamin C in broccoli (Brassica oleracea L.) with qualitative and quantitative analysis. Qualitative analysis was performed using specific reagents that ammonium molybdate, Fehling Fehling's A and B which have indicated a positive sample containing vitamin C, and vitamin C were analyzed quantitatively using UV- Vis spectrophotometry at a wavelength of 570 nm. The results showed levels of vitamin C in raw broccoli 0.62915 mg/g and steamed broccoli 0.45449 mg/g.
Identification of Formalin in Raw Tofu from Sidenreng Rappang District Traditional Markets Hasrianti, Hasrianti; Suhaenah, Asriani; Pratama, Mamat
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.290

Abstract

Formalin (Formaldehyde) is a chemical compound whose use is prohibited as a preservative in food additives. This study aims to analyze the content of formalin (Formaldehyde) in raw tofu circulating in Sidenreng Rappang district. The test method used was by qualitative analysis using Schiff reagent and KMnO4. The quantitative analysis using the UV-Vis spectrophotometry method. The test results used Schiff reagent and KMnO4, the four tofu samples contained formalin. Test results on the UV-Vis Spectrophotometry method at a wavelength of 555 nm, obtained formalin levels in sample with sample code A = 1.130%, sample code B = 1.826%, sample code C = 1.84%. It can be concluded that in the formaldehyde qualitative analysis test on raw tofu, the three samples positively contained formaldehyde. As well as the results of the measurement of the three positive samples containing formaldehyde using a UV-Vis spectrophotometer.
Hydroquinone Levels in Whitening Body Lotion Circulating in Makassar City by the UV-Vis Spectrophotometry Method Rezky M, Mega; Suhaenah, Asriani; Baits, Muzakkir
Pharmaceutical Reports Vol 2, No 2 (2023): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v2i2.272

Abstract

Hydroquinone is an active compound that is able to control pigment production to inhibit melanin formation and has activity as a skin whitening agent, so hydroquinone is widely used in cosmetic products. Hydroquinone has adverse side effects if used for a long time. BPOM RI has issued a regulation on the prohibition on the use of hydroquinone as a bleach in cosmetics. The purpose of this study was to identify the hydroquinone content in whitening handbody samples circulating in Makassar City and to find out the level of hydroquinone contained in the sample. Qualitative analysis is carried out using FeCl₃ reagents and quantitative analysis using the UV-VIS spectrophotometry method. The number of samples used in this study was as many as 4 samples that did not have a registration number from BPOM RI. The results showed that the 4 samples studied positively contained hydroquinone. The results of the sample test measured at a maximum wavelength of 292 nm, obtained hydroquinone levels at the sample code HB1 = 1.267%; sample code HB2 = 0.912%; sample code HB3 = 0.379% and sample code HB4 = 0.449%.
Formulation of Seaweed (Eucheuma cottonii Doty) Lotion Hamsinah, Hamsinah; Suhaenah, Asriani; Mulyana, Imam Dwiyan
Pharmaceutical Reports Vol 2, No 2 (2023): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v2i2.274

Abstract

Seaweed (Eucheuma cottonii Doty) has potential as an antioxidant because it contains kappa-carrageenan which can counteract free radicals. Formulation of seaweed (Eucheuma cottonii Doty) into lotion preparations can minimize the negative effects of sun exposure, because it can reflect solar radiation or work as a physical sunscreen. To give the maximum effect, particle size reduction is carried out, so that the smaller the particle size of the seaweed powder, the surface area increases. This study aims to determine the formulation and evaluate the preparation of lotion from seaweed powder. This research was conducted using an experimental method. The lotion was made with three variations of seaweed powder concentration (Eucheuma cottonii Doty), namely 2.5%, 3% and 5%. Tests were carried out before and after accelerated conditions at 5oC and 35oC for 12 hours each for 12 cycles with test parameters including organoleptic, homogeneity, pH, spreadability, viscosity and flow type. The results obtained in the organoleptic test showed no change in the three formulas both before and after the accelerated condition. The pH test showed that Formula 2 and Formula 3 still showed that the preparation remained in the skin pH range for sunscreen. In the homogeneity test, all preparations were homogeneous, as well as the spreadability test met the test requirements criteria. Based on the tests carried out, it can be concluded that formulas 2 and 3 have optimum stability.
Analysis of Artificial Sweeteners, Sodium Cyclamate, in Packaged Beverages and Powders by the Gravimetric Method Pratama, Shinta Indah; Suhaenah, Asriani; Tahir, Masdiana
Pharmaceutical Reports Vol 2, No 2 (2023): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v2i2.267

Abstract

Most people like instant beverage products because of their practical processing and superior taste and creative packaging, thus attracting consumers to consume them. One of the food additives that is often used in instant beverage products is artificial sweeteners such as sodium cyclamate which has a sweetness level of 3.94 kcal/g or 30 times that of sucrose. This study aims to determine the levels of sodium cyclamate in packaged and powdered drinks circulating on the campus of the Indonesian Muslim University using the gravimetric method. The sampling method used a purposive technique and obtained 6 test samples, qualitative analysis used the precipitation method and obtained all positive samples containing sodium cyclamate. The results of the quantitative analysis obtained the levels of sodium cyclamate for each sample A; B; C; D; E; F as much as 37.07 mg/kg; 30.17 mg/kg; 12.93 mg/kg; 4.31 mg/kg; 340 mg/kg; 258 mg/kg. Thus, these results indicate that all samples do not exceed the levels set by BPOM regulation No. 11 of 2019 concerning food additives, namely 350 mg/kg, so they are safe for consumption.
Determination of Phenolic and Flavonoid Content of Ethanol Extract of Manila Sawo Leaf (Manilkara zapota L.) from Wajo District by Uv-Vis Spectrophotometry Suhaenah, Asriani; Hartina, Suki; Aminah, Aminah
Pharmaceutical Reports Vol 3, No 2 (2024): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i2.311

Abstract

Sapodilla Manila (Manilkara zapota L.) is a plant that is widely known by the public. People usually use sapodilla leaves as traditional medicine. Efficacy obtained from the presence of phenolic compounds and flavonoids in these plants. This study aims to determine the phenolic and flavonoid content of ethanol extract in sapodilla leaves (Manilkara zapota L.) from Wajo district. This research method used UV-Visible spectrophotometry and the reference standard used were gallic acid (phenolic) and quarcetin (flavonoid). The results showed that the average phenolic content of the ethanol extract of sapodilla leaves at a concentration of 100 ppm was 150.28 mgGAE/g extract and the average flavonoid content of the ethanol extract of sapodilla leaves at a concentration of 300 ppm was 36.577 mgQE/g extract.
Determination of Tannin in Ethanol Extract of Bajakah Tampala Root (Spatholobus littoralis Hassk) as an Anticholesterol Saskia, Eka Putri; Tahir, Masdiana; Suhaenah, Asriani
Pharmaceutical Reports Vol 4, No 2 (2025): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i2.377

Abstract

The root of Bajakah Tampala (Spatholobus littoralis Hassk.) is known to contain several bioactive secondary metabolites, including saponins, flavonoids, phenolics, and tannins, which contribute to its broad pharmacological potential. Among these compounds, tannins play an important role in various therapeutic applications such as hemostasis, burn treatment, and the management of diarrhea, dysentery, and tumors. In addition, tannins possess anticholesterol properties by precipitating mucosal proteins on the surface of the small intestine, thereby reducing the absorption of cholesterol and lipids into the bloodstream. This study aimed to determine the tannin content in the ethanol extract of Bajakah Tampala root as part of an investigation into its potential as a natural anticholesterol agent. The extraction process was carried out using the maceration method with 96% ethanol as the solvent to ensure efficient recovery of phenolic compounds. Quantitative analysis of tannin content was performed using the UV-Visible spectrophotometric method at a wavelength of 750 nm, with gallic acid employed as the standard reference compound. The results showed that the tannin concentration in the ethanol extract of Bajakah Tampala root was 91.699 mg GAE/g extract (milligrams of gallic acid equivalent per gram of extract). These findings suggest that Bajakah Tampala root possesses a high tannin content, supporting its potential development as a natural anticholesterol agent and contributing to the growing evidence of its pharmacological benefits in traditional medicine.
Antioxidant Activity of Ethanol Extract of Kepok Banana Peel (Musa paradisiaca L.) by Ferric Reducing Antioxidant Power Method Damang, Irda Binti; Suhaenah, Asriani; Razak, Rais
Pharmaceutical Reports Vol 4, No 2 (2025): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i2.379

Abstract

Antioxidants are compounds capable of neutralizing the harmful effects of oxidants by donating electrons to unstable molecules, thereby preventing oxidative damage. These compounds play a vital role in protecting biological systems from oxidative stress, which is associated with aging and various chronic diseases. Kepok banana (Musa paradisiaca Linn.) peel is an underutilized natural resource rich in secondary metabolites such as saponins, flavonoids, alkaloids, tannins, and quinones, many of which are known for their strong antioxidant potential. The present study aimed to evaluate the antioxidant activity of the ethanol extract of kepok banana peel using the Ferric Reducing Antioxidant Power (FRAP) method. Extraction was performed by maceration with 96% ethanol as the solvent to obtain a concentrated extract. The FRAP assay was carried out by reacting the extract with FRAP reagents and measuring the absorbance using a UV–Vis spectrophotometer at a maximum wavelength of 710 nm. Quercetin was used as a standard antioxidant reference, producing a calibration curve with a linear regression equation of y = 0.0203x + 0.0301 and a correlation coefficient (r) of 0.9965, indicating excellent linearity. The results revealed that the ethanol extract of kepok banana peel exhibited high antioxidant capacity, with a value of 81.6939 mgQE/g extract. These findings suggest that kepok banana peel is a promising natural source of antioxidants and could potentially be developed into functional ingredients for pharmaceutical and nutraceutical applications.