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Journal : MPSJ

Antioxidant activity Antioxidant activity of ethanol extract of bitti leaves (Vitex cofassus Reinw. ex. Blume) using the dpph free radical scavenging method Bahari, Dita Wulan; Suhaenah, Asriani; Muflihunna, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.288

Abstract

Antioxidants are compounds that can counteract free radicals in the body, reduce oxidation in cells and cell damage. The purpose of this study was to determine the antioxidant activity of ethanol extract of bitti leaves (Vitex cofassus Reinw. Ex. Blume with DPPH (2,2- diphenyl-1-picrylhydrazyl) scavenging method. The absorbance was measured by UV-Vis spectrophotometer at 510 nm wavelength. The results showed the presence of antioxidant activity with IC50 value of 56.59 μg/mL with strong antioxidant activity category, while quercetin as a comparator has very strong antioxidant activity with IC50 value of 5.93 μg/mL.
Antioxidant Activity Aktivitas Antioksidan Ekstrak Etanol Daun Lerak (Sapindus rarak DC) Dengan Metode Peredaman Radikal Bebas DPPH Asri, Fitriani; Suhaenah, Asriani; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.289

Abstract

FITRIANI ASRI. Antioxidant Activity Of Ethanol Extract Of Lerak eaves (Sapindus rarak) Using The DPPH Free Radical Reduction Method (Supervised by Asriani Suhaenah dan St. Maryam) Lerak leaves (Sapindus rarak) are a traditional plant used by the community to treat various diseases. The secondary metabolic compounds contained in the lerak plant (Sapindus rarak) which have potential as antioxidants are flavonoids, alkaloids, saponins, tannins, quinones, steroids and triterpenoids which are obtained through extraction using ethanol solvent. This research aims to determine the antioxidant activity of the ethanol extract of lerak leaves (Sapindus rarak) using the DPPH free radical reduction method (1,1-diphenyl-2-picrihydrazyl). The antioxidant value was measured using UV-Vis spectrophotometry at a wavelength of 516 nm. The calculation results show an IC50 value of 876,592 μg/mL (very weak category) while quercetin as a comparison has very strong antioxidant activity with an IC50 value of 1,882 μg/mL.
analisis kadar analisis kadar senyawa tanin pada teh daun tanaman kakao (theobroma cacao L.) secara spektrofotometri UV-Vis arifin, nurrizky afiah; Suhaenah, Asriani; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.291

Abstract

Cocoa leaves (Theobroma cacao L.) contain secondary metabolite compounds, namely flavonoids, saponins, tannins, theobromine, caffeine, anthocyanins, leucoanthocyanins and catechol. This research aims to determine the levels of tannin compounds contained in tea preparations from the leaves of the cocoa plant (Theobroma cacao L.) based on a comparison of growing places, namely Wajo, Jeneponto and Malino. The research was carried out qualitatively using wet reagents and quantitatively using the UV-Vis spectrophotometric method. Based on the qualitative test results, FeCl3 1% reagent produces a green solution blackish, the gelatin test produces precipitation, while the potassium ferricyanide and ammonia reagent produces a dark brown color, these results indicate that cocoa leaves contain tannin compounds, for the quantitative test it is measured using UVVis spectrophotometry at a maximum wavelength of 772 nm with a reference, namely gallic acid. . The results obtained for the Wajo area were 1,618mgGAE/g, Jeneponto 2,334mgGAE/g, and Malino 1,030mgGAE/g, based on these data it can be concluded that cocoa leaves contain tannin compounds and the highest levels are in the Jeneponto area.
Antioxidant Activity ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT OF RED BAJAKAH KALALAWIT ROOTS (Uncaria gambir Roxb) USING THE FRAP METHOD Aris, Arru'nnisa Ika Nur Ilmi; Baits, Muzakkir; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 4 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i4.302

Abstract

Akar bajakah kalalawit merah (Uncaria gambir Roxb) merupakan salah satu tanaman yang dikenal memiliki kandungan alkaloid, fenol, dan triterpenoid yang digunakan untuk mengobati kanker, tumor, luka, penuaan dini, diabetes, dan antioksidan. Antioksidan adalah suatu senyawa yang memiliki struktur molekul yang dapat memberikan elektron untuk molekul radikal bebas yang tidak stabil tanpa terganggu sama sekali sehingga dapat memutuskan reaksi berantai radikal bebas. Tujuan penelitian ini adalah untuk mengetahui aktivitas antioksidan ekstrak etanol akar bajakah kalalawit merah (Uncaria gambir Roxb) menggunakan metode FRAP, berdasarkan kemampuan sampel mereduksi ion Fe3+ menjadi Fe2+. Hasil pengujian kualitatif menunjukkan bahwa akar bajakah kalalawit merah (Uncaria gambir Roxb) mengandung senyawa alkaloid, flavonoid, fenolik,dan tannin. Hasil pengujian kuantitatif diperoleh nilai rata-rata aktivitas antioksidan ekstrak etanol akar bajakah kalalawit merah (Uncaria gambir Roxb) yaitu sebesar 193,403 mg QE/g ekstrak.