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THE EFFECT OF PRE-OPERATION BASED EDUCATION ON ANXIETY REDUCTION AMONG PATIENTS WITH POST OPEN REDUCTION INTERNAL FIXATION Firman Oswari; Dwikora Novembri Utomo; Ninuk Dian Kurniawati
International Journal of Nursing and Health Services (IJNHS) Vol. 2 No. 4 (2019): International Journal of Nursing and Health Services (IJHNS)
Publisher : Alta Dharma Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.597 KB) | DOI: 10.35654/ijnhs.v2i4.168

Abstract

Open Reduction Internal Fixation (ORIF) is one of the management among patients who have a fracture. The study aimed at examining the effect of health education pre-operation anxiety reduction among fracturing patients cruris post open reduction internal fixation. A quasi-experimental, pre-test and post-test with non-equivalent control group was applied in this study. Thirty-four samples were recruited by using total sampling and divided into two intervention and control groups. Data analysis was performed and presented in descriptive statistics, and significant findings were computed using the paired t-test. Results: The results showed that the mean anxious level intervention group downhill from 28,76+4,603 to 16,61+2,487 after the intervention. Meanwhile, in the control group, the mean anxious level slightly downhill from 28,18+4,066 to 23,82+4,362. The paired t-test obtained a p-value of 0.000, indicating that there were significant differences in the decrease in anxiety level between the intervention and the control group. Conclusion: Preoperative health education interventions based on the health belief model can reduce the level of anxiety in patients with cruris fractures after ORIF surgery. The nurse profession is expected to be able to use preoperative health education actions based on the health belief model to become one of the independent nursing interventions. Keywords: pre-operation based education, fracture, anxiety reduction
Profile of Age, Gender, and Body Mass Index in Patient with Knee Osteoarthritis in Surabaya Primadita Esther Rosita; Patricia Maria Kurniawati; Dwikora Novembri Utomo
Surabaya Physical Medicine and Rehabilitation Journal Vol. 3 No. 1 (2021): SPMRJ, FEBRUARY 2021
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v3i1.22355

Abstract

Background: Osteoarthritis is a degenerative disease which attacks all the joint parts, including articular cartilage, subchondral bone, ligament, meniscus, capsule, synovium, and periarticular tissue. Among various joints in human body, knee joint is the most affected by osteoarthritis. There are several established risk factors for knee osteoarthritis, including age, female gender, and obesity.Aim: This study aimed to describe age, gender, and body mass index (BMI) profile in knee osteoarthritis patients.Material and methods: This was a retrospective descriptive study with total sampling of 292 medical records of patient with knee osteoarthritis from Physical Medicine and Rehabilitation outpatient clinic, Universitas Airlangga Hospital, Surabaya.Results: Of all the data, there were 130 medical records included in this study. The majority characteristic of the subjects were older than 60 years old (54.6%), 98 (75.4%) were females and 32 (24.6%) were males. The highest male-female ratio was on 45-59 years old (1:4). Most patients were obese (58.5%) with the highest percentage was on 45-59 years old (51.3%).Conclusion: The majority of osteoarthritis patients in Universitas Airlangga Hospital Surabaya were elderly, females, and obese people.
Risk Estimation of Anterior Cruciate Ligament (ACL) Injury in East Java Puslatda Pencak Silat Athletes Farhan Nur Ahmad Dzakiya; Damayanti Tinduh; Dwikora Novembri Utomo
Surabaya Physical Medicine and Rehabilitation Journal Vol. 3 No. 1 (2021): SPMRJ, FEBRUARY 2021
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v3i1.23190

Abstract

Background: Dr. Soetomo General Hospital Sports Clinic Surabaya reported that the incidence of knee injuries was rather high, particularly in martial art athletes. Injuries in pencak silat athletes are dominated by Anterior Cruciate Ligament (ACL) injuries (16.7%) Several risk factors are thought to influence ones’ propensity for these injuries.Aim: To analyze risk estimation between intrinsic and extrinsic factors in the occurrence of ACL injury in East Java Puslatda Pencak Silat Athletes.Material and Methods: This study was an analytic observational study with a case control design involving 18 pencak silat athletes from East Java Regional Training Centre. Age, gender, body mass index, previous ACL injury, range of motion, laxity, and flat foot were included as intrinsic factors; while duration of each training, training frequency, and sparring frequency were included as extrinsic factors. Data analysis was done using the Chi-Square Test. Odds Ratio was calculated through cross-tabulation.Results: It was found that 3 of 18 athletes (16.7%) had ACL injuries. None of the intrinsic and extrinsic factors significantly affected the incidence of ACL injury (p> 0.05). However, the odds ratio calculation showed that adult athletes older than 25 years-old (OR = 1.4), male (OR = 1.667), obese (OR = 1.4), with laxity (OR = 2.5), and flat foot (OR = 1) had higher risk in having ACL injury.Conclusion: Adult athletes, male, obese, with laxity, and flat foot had a higher risk of ACL injury.
Prevalence of Knee Injury in East Java’s Puslatda Fencing Athletes Farah Yusrania; Damayanti Tinduh; Dwikora Novembri Utomo; Lilik Herawati
Surabaya Physical Medicine and Rehabilitation Journal Vol. 3 No. 2 (2021): SPMRJ, AUGUST 2021
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v3i2.25169

Abstract

Background: Fencing is one of many sports that are held in major sports events, both nationally and internationally. Fencing also has a high risk of injury, and knee injury is the most common injury site according to the authors' observations. Even so, studies on knee injuries in fencing athletes are very scarce, especially in Indonesia.Aim: To ascertain the prevalence of knee injuries and its intrinsic risk profile in fencing athletes at East Java Puslatda (regional training center).Material and Methods: The method used in this study was descriptive observational based on athletes’ health screening data, which were obtained from Sport Clinic Dr. Soetomo Academic General Hospital and athletes’ fitness data obtained from KONI.Results: This research involved 14 fencing athletes that were active in the East Java regional training center. Out of the 14 athletes who were included in this study, it was found that 1 athlete (7.1%) had a knee injury and 13 athletes (92.9%) had no knee injury. The athlete who had injured was a senior overweight female, had history of knee injury, average VO2max, normal knee ROM and alignment, and did 1-2 times leg strengthening exercises every week.Conclusion: The prevalence of knee injuries in fencing athletes at East Java regional training center is 1 in 14 athletes.
THE ROLE OF PLATELET-RICH FIBRIN FACILITATES THE HEALING OF GASTROCNEMIUS MUSCLE DEFECT: A PRELIMINARY STUDY ON ANIMAL MODEL Dwikora Novembri Utomo; Kukuh Dwiputra Hernugrahanto
Journal Orthopaedi and Traumatology Surabaya Vol. 7 No. 1 (2018): April 2018
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v7i1.2018.31-41

Abstract

Background: Scar formation has been a classical issue in the healing of skeletal muscle defect which will results in decrease of strength and function. Platelet-rich plasma (PRP) has been studied to enhance the healing of muscle defect. The disadvantages of it include the risk of immunologic reaction, time-consuming preparation, and lack of scaffold element. Platelet-rich fibrin (PRF) is a new generation of platelet concentrate that provides good source of growth factors and scaffold element necessary for the healing. This study is to provide a fondation of PRF preparation and implantation for the healing of experimental defect of gastrocnemius muscle in an animal model.Purpose: The goal is to provide a fondation of PRF preparation and implantation for the healing of experimental defect of gastrocnemius muscle in an animal model.Methods: Animal Care and Use Committee, Airlangga University approved the study. Twenty New Zealand white rabbits were divided into two groups. In control group, a defect was created in the right gastrocnemius and no implantation was done. In study group, similar defect was created with implantation of PRF. Two and four weeks after surgery, the defect was examined immunohistochemically for the expression of Pax7 protein.Results: The implanted group showed higher IRS score in two and four weeks compared to the control group.Conclusion: The use of PRF facilitates the healing of muscle injury. This study will be used as a fondation for further study on PRF.
THE EFFECT OF DECELLULARIZATION TECHNIQUE ON COLLAGEN TYPE II AND MATRICES POROSITY OF CARTILAGE BOVINE SCAFFOLD Dwikora Novembri Utomo; Ika Benny Kartika Sari
Journal Orthopaedi and Traumatology Surabaya Vol. 7 No. 1 (2018): April 2018
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v7i1.2018.42-54

Abstract

Background: Cartilage has limited capacity for self-repair in case of defect. Stem cell based tissue engineering has become an alternative therapy for the treatment of cartilage defect. The use of decellularized cartilage bovine can serve as scaffold to support proliferation dan differentiation of the stem cell.Purpose: This research is to compare the effect of decellularization technique on collagen type II and matrices porosity of cartilage bovine scaffold.Methods: This experimental laboratory research used cartilage bovine scaffold which was decellularized using physical, chemical and enzymatic techniques with different time and concentration variations, then collagen type II measurement was performed by immunohistochemical method and evaluation of porosity size with electron microscopy.Results: In the preparations with the highest concentration and the longest immersion time of 5% SDS for 72 hours, the decellularization process occurs perfectly. The collagen type II content was found to have significantly higher concentrations than the controls and other preparations, and have interconnected porosities in large size.Conclusion: High concentrations of collagen type II  and large diameter of pores after decellularization process in cartilage bovine scaffold confirm that this scaffold still has optimum biochemical cues that can be a good mechanical framework and microenvironment stem cell in effort to repair the cartilage defects. This result was expected to become a standard for the decellularization making of cartilage bovine scaffold.
CYTOTOXIC EFFECT OF FREEZE DRIED BOVINE CARTILAGE POWDER AND PLATELET RICH PLASMA (PRP) TO MESENCHYMAL STEM CELL (MSCs) Dwikora Novembri Utomo; Anthoni Yusbida
Journal Orthopaedi and Traumatology Surabaya Vol. 6 No. 2 (2017): October 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v6i2.2017.63-70

Abstract

Cartilage repair is a challenging clinical problem because the damage is an irreversible condition. Many studies had been performed using several kinds of natural or synthetic scaffold. Attempts to repair articular cartilage using scaffold usually found many problems, lacks the physical structure and mechanical properties necessary to ensure long-term efficacy to cartilage defect. Furthermore, scaffold frequently cause toxicity to the host. Therefore, this study was performed in vitro to test the toxicity effect of scaffold freeze dried bovine cartilage powder and platelets Rich Plasma (PRP). This research was conducted using pure experimental research design in 4 groups of animal stem cells which being added with scaffold freeze dried bovine cartilage scaffold provided with platelet rich plasma. This study using posttest only control group design. The result being processed with MTT assay and spectrophotometer for counting the viable stem cells. There was no significant difference in the amount of macrophage between control and the freeze dried bovine cartilage scaffold provided with PRP (p=0,128). With this result in the number of macrophages between the control with freeze dried bovine cartilage scaffold provided PRP, it can be concluded that these biomaterials have biocompatibility.
THE EFFECT OF PLATELET RICH PLASMA ON MESENCHYMAL STEM CELLs (MSCs) DIFFERENTIATION INTO CHONDROBLAST Dwikora Novembri Utomo; I Gde Adi Widiastana
Journal Orthopaedi and Traumatology Surabaya Vol. 6 No. 2 (2017): October 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v6i2.2017.80-85

Abstract

The addition of platelet rich plasma to mesenchymal stem cell culture on growth  media and  chondrogenic  media  had  any effect  on stem cell’s proliferation and differentiation into chondroblast has not been determined. This research is to find  out  the  effect  of  platelet  rich  plasma  on  mesenchymal  stem  cell’s differentiation and proliferation into chondroblast on in vitro media. Randomized control group posttest only design. Blood was taken from the rabbit’s vein to be processed into platelet rich plasma (PRP). Mesenchymal Stem Cell (MSC) was harvested from the bone marrow of the rabbit to be cultured. The MSC’s culture were divided into three groups of modification. The first group was combination of MSC added with Complete Culture Medium (CCM) and Chondrogenic Diferentation Medium (CDM) without PRP as control group. The second group had the same combination as the first group with extra 5% PRP. The third group had the same combination as the first group with extra 10% PRP. The results were evaluated in the following 21 days. The group that received extra 5% PRP had significant increase of chondroblast count compared to the group without PRP addition (p=0,033). The same result also occured on the groups that received extra 10% PRP compared to the group without PRP addition (p=0,028). There were no significant diferences between both the second and the third groupchondroblast count (p=0,203). There was a significant effect of platelet rich plasma on mesenchymal stem cell’s diferentiation and proliferation into chondroblast on invitro media.
EFFECT OF PLATELET RICH FIBRIN AND MESENCHYMAL STEM CELL ON MYOBLAST AND FIBROBLASTS RATIO IN RABBIT MUSCLE DEFECT Dwikora Novembri Utomo; Mohammad Zaim Chilmi; Angga Fiandana
Journal Orthopaedi and Traumatology Surabaya Vol. 7 No. 2 (2018): October 2018
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v7i2.2018.95-105

Abstract

Background: One of the problems in Orthopedics which often results in less satisfactory outcomes is the muscle injuries treatment. This is due to slow healing process and outcome has not been optimal because it produces scar tissue.Purpose: To evaluate effect of platelet rich fibrin and allogenic mesenchymal stem cell on muscle regeneration through comparation of myoblast and fibroblast ratio.Methods: This research is true experimental with randomized pre and post test with control group design. The treatment group included administering allogenic mesenchymal stem cells (MSC), rich fibrin platelets (PRF), and a combination of both. The study subjects were New Zealand White Rabbit which gastrocnemius muscle is incised. Muscle quality evaluation was done in the second and fourth weeks through histology examination in the form of myoblast cell ratio to fibroblast.Results: In the second week evaluation, administering allogenic MSC combined with PRF gave significant results to an increase in myoblast cell ratio to fibroblast. While evaluation of fourth week, giving of three treatment groups gave significant result to myoblast cell ratio to fibroblast.Conclusion: Allogenic MSC administration combined with PRF can improve New Zealand White Rabbit muscle healing quality by histological examination.
THE EFFECT OF TRANEXAMIC ACID INJECTION ON HEMOGLOBIN LEVEL, ALBUMIN LEVEL, AND PAIN ON PATIENT RECEIVING TOTAL KNEE REPLACEMENT Dwikora Novembri Utomo; Teddy Heri Wardhana; Ahmad Hannan Amrullah; Hamzah Hamzah
Journal Orthopaedi and Traumatology Surabaya Vol. 8 No. 1 (2019): April 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v8i1.2019.1-11

Abstract

Background: The high number of knee osteoarthritis cases could lead arthroplasty more frequent. Total Knee Replacement (TKR) surgery procedure is at risk of massive bleeding. Bleeding can affect albumin levels and the onset of intra-compartment pressure on the nerves. The use of tranexamic acid could be done to reduce bleeding.Objective: Proving the effect of intravenous tranexamic acid administration on patients who will undergo TKR surgery.Methods: The experiment was conducted experimentally using primary laboratory data obtained before and after surgery in patient which will be performed TKR operation starting from April 2017.Result: There are 64 patients who had undergone total knee replacement surgery. The mean preoperative hemoglobin in the tranexamic acid group and without tranexamic acid was 13.06±1.46g/dl and 12.44±0.87g/dl. The mean hemoglobin after surgery was 10.29 ±1.14 g/dl and 9.16±0.97 g/dl. In the group receiving tranexamic acid, 32 (100%) reported low postoperative VAS scores, did not require blood transfusions and did not require albumin transfusion. Groups not receiving tranexamic acid, 32 (100%) moderate postoperative VAS scores, 4 people (12.5%) required the blood transfusion, and 3 (9.4%) required transfusion of albumin.Conclusion: The results of this study showed that the group given tranexamic acid had higher hemoglobin levels after surgery than the untreated group of tranexamic acid; there was no difference in albumin levels after surgery in both groups; the administration of tranexamic acid will decrease the amount of blood loss, decrease the degree of pain, and decrease the need for blood transfusions after total knee replacement surgery.