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All Journal Medical Journal of Indonesia Jurnal Daulat Hukum Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Health Information : Jurnal Penelitian Community Development Journal: Jurnal Pengabdian Masyarakat Sewagati: Jurnal Pengabdian Masyarakat Indonesia Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Jurnal Kesehatan Amanah Jurnal Pengabdian West Science Jurnal Pengabdian Masyarakat Nian Tana
Frisca Frisca
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Application of a modified method for stem cell isolation from lipoaspirates in a basic lab Sardjono, Caroline T.; Setiawan, Melina; Frisca, Frisca; Saputra, Virgi; Aniko, Gwendy; Sandra, Ferry
Medical Journal of Indonesia Vol 18, No 2 (2009): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (718.567 KB) | DOI: 10.13181/mji.v18i2.343

Abstract

Aim Lipoaspirate, a wasted by product from liposuction procedure recently has been shown to contain abundant mesenchymal stem cells (MSCs). MSCs have been studied in many research areas to regenerate many cell lineages including, myogenic, cardiomyogenic, and angiogenic lineages. The large quantity of MSCs in lipoaspirate, makes it an attractive source for stem cells used in research and clinical applications. A simplified method which is suitable to be performed in a basic laboratory will facilitate development of stem cell research in developing countries. Therefore the outcomes from this study are expected to encourage the progress of stem cell research in Indonesia.Methods Lipoaspirate was digested using collagenase type I, followed by a basic filtration method. Purification of MSCs was done by cell culture for 2-3 days followed by supernatant removal. To confirm the homogenous population of MSCs, an analysis using flowcytometry was performed based on the MSCs minimal criteria developed by Mesenchymal and Tissue Stem Cell Committee of the International Society of Cell Therapy.Resuts MSCs were able to be obtained at 16.41 ± 8.22 x 108 cells per 120 ml lipoaspirate. The cultured cells showed fibroblastic morphology which is characteristic for MSCs and were able to be purified from non-MSCs cells. This was confirmed by flowcytometry assay showing expression of CD105 and the absence of HLA-Class II, CD 45, CD 34, CD14, and CD19.Conclusions This study has shown that it was feasible to isolate messenchymal stem cell from human lipoaspirate. The procedure was practicable to be performed within a basic laboratory. (Med J Indones 2009; 18: 91-6)Keywords: mesenchymal stem cell, lipoaspirate, stem cell isolation technique
PREVALENSI OBESITAS SENTRAL BERDASARKAN LINGKAR PINGGANG PADA PENGEMUDI BUS ANTAR KOTA Frisca, Frisca; Karjadidjaja, Idawati; Santoso, Alexander Halim
Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Vol 3, No 2 (2019): Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan
Publisher : Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmstkik.v3i2.3911

Abstract

Central obesity has become a public health problem which is currently rapidly increasing throughout the world, including in developing countries like Indonesia. The World Health Organization states that central obesity is a major risk factor for various cardiometabolic diseases, such as diabetes and hypertension. Inter-city bus drivers are high-risk occupations of cardiometabolic disease, this is due to unhealthy lifestyles and work patterns such as high consumption of fatty foods, smoking habits, lack of physical activity, long driving times and irregular sleep patterns. This study aims to determine the prevalence of central obesity based on waist circumference in inter-city bus drivers. This research is a descriptive cross sectional study. Data obtained from measurements of body weight, height and waist circumference, as well as calculation of body mass index (BMI) on 176 subjects obtained through consecutive sampling method. Obesity is said if BMI ≥25 according to WHO criteria for Asia-Pacific and central obesity if waist circumference> 90 cm for men and> 80 cm for women. In this study all subjects were men with an average age of 42.45  10.50 years. Based on the calculation of BMI there are 54.3% of subjects obese. Through measurement of waist circumference there are 50.6% of subjects with central obesity. Providing education is very important so that subjects can make lifestyle changes for the better so as to prevent cardiometabolic disease in inter-city bus drivers. AbstrakObesitas sentral telah menjadi masalah kesehatan masyarakat yang saat ini sangat meningkat pesat di seluruh dunia, termasuk di negara berkembang seperti Indonesia. World Health Organization menyatakan bahwa obesitas sentral merupakan faktor risiko utama terjadinya berbagai penyakit kardiometabolik, seperti diabetes dan hipertensi. Pengemudi bus antar kota merupakan pekerjaan dengan risiko tinggi terkena penyakit kardiometabolik tersebut, hal ini disebabkan karena gaya hidup dan pola kerja yang tidak sehat seperti tingginya konsumsi makanan berlemak, kebiasaan merokok, kurangnya aktivitas fisik, durasi menyetir yang lama dan pola tidur yang tidak teratur. Penelitian ini bertujuan  untuk mengetahui prevalensi obesitas sentral berdasarkan lingkar pinggang pada pengemudi bus antar kota. Penelitian ini merupakan penelitian deskriptif dengan desain potong lintang. Data diperoleh dari pengukuran berat badan, tinggi badan dan lingkar pinggang, serta  perhitungan indeks massa tubuh (IMT) pada 176 subjek yang diperoleh melalui metode consecutive sampling. Dikatakan Obesitas jika  IMT ≥25 menurut kriteria WHO untuk Asia-Pasifik dan obesitas sentral jika lingkar pinggang >90 cm untuk laki-laki dan >80 cm untuk perempuan. Pada penelitian ini semua subjek adalah laki-laki dengan usia rata-rata 42.45 ± 10.50 tahun. Berdasarkan perhitungan IMT terdapat 54.3% subjek mengalami obesitas. Melalui pengukuran lingkar pinggang terdapat 50.6% subjek dengan obesitas sentral. Pemberian edukasi sangat penting agar subjek dapat melakukan perubahan gaya hidup menjadi lebih baik sehingga dapat mencegah terjadinya penyakit kardiometabolik pada pengemudi bus antar kota.
Edukasi Dan Penilaian Kadar Albumin Pada Kelompok Lanjut Usia Dalam Pencegahan Sarkopenia Frisca Frisca; Santoso, Alexander Halim; Warsito, Jonathan Hadi; Syarifah, Andini Ghina; Gunaidi, Farell Christian; Destra, Edwin; Firmansyah, Yohanes
SEWAGATI: Jurnal Pengabdian Masyarakat Indonesia Vol. 3 No. 2 (2024): Juni: Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/sewagati.v3i2.1524

Abstract

Sarcopenia is a medical condition characterized by a progressive decrease in skeletal muscle mass as well as muscle strength. Sarcopenia in the elderly causes an increased risk of falls, fractures and mortality. The main risk factors include advanced age, lack of physical activity, malnutrition, and chronic disease. Deficiency of albumin, a protein important for maintaining osmotic pressure and nutritional status, is often associated with malnutrition and sarkopenia. This community service activity was attended by 93 elderly people with an average age of 74 years. The results showed that the majority of participants had normal albumin levels, but there was a significant proportion who experienced hypoalbuminemia, more commonly found in men than women. Education and screening are carried out to increase awareness regarding the importance of albumin intake in preventing sarkopenia. A holistic and integrated nutritional approach is needed in the management of sarcopenia. Appropriate nutritional interventions, including increasing protein intake from foods such as snakehead fish, can increase serum albumin levels and prevent muscle mass loss. Collaboration between nutritionists, physicians, and other health professionals is essential to designing and implementing a comprehensive treatment plan. It is hoped that with appropriate monitoring and treatment, the quality of life of elderly people with sarkopenia can be improved. Keywords: albumin, education, hypoalbuminemia, elderly, sarcopenia
Hubungan Konsumsi Makanan Cepat Saji Dengan Status Gizi Mahasiswa Fakultas Kedokteran Universitas Tarumanagara Di Masa Pandemi Covid-19 San Murdoko, Ilham Wicaksono; Frisca, Frisca
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Salah satu masalah kelebihan gizi yang terjadi pada anak dan remaja serta mendapatkan perhatian khusus di dunia kesehatan adalah obesitas. Beberapa faktor risiko yang menyebabkan meningkatnya prevalensi obesitas khususnya obesitas pada remaja adalah terjadinya perubahan pola hidup. Pandemi COVID-19 memperbesar risiko terjadinya obesitas pada anak dan remaja karena perubahan gaya hidup. Tujuan dilakukannya penelitian ini adalah untuk mengetahui hubungan antara konsumsi makanan cepat saji dengan kejadian overweight dan obesitas di masa pandemi COVID-19. Penelitian ini menggunakan desain penelitian berupa jenis analitik dengan pendekatan Cross-Sectional. Pengambilan subjek dilakukan dengan purposive non probability sampling dan didapatkan sebanyak 201 mahasiswa menjadi responden dalam penelitian ini. Penelitian ini dilakukan secara daring dengan memberikan kuesioner melalui google form. Analisis statistik menggunakan table 2x2 dengan uji chi-square dan didapatkan hasil mayoritas subjek berjenis kelamin perempuan dengan rata–rata usia 20,30 tahun. Pada penelitian ini didapatkan 98 (48,7%) subjek menderita gizi lebih yaitu overweight dan obesitas, juga sebagian besar subjek (69,2%) mengalami peningkatan berat badan selama pandemi COVID-19. Pada penelitian ini juga didapatkan sebelum masa pandemi terdapat 50 (24,9%) subjek yang mengonsumsi makanan cepat saji ? 3x/minggu dan selama masa pandemi sebanyak 70 (34,8%) subjek mengonsumsi makanan cepat saji ?3x/minggu. Dari penelitian ini dapat disimpulkan bahwa tidak terdapat hubungan yang bermakna antara kebiasaan konsumsi makanan cepat saji dengan status gizi (p = 0,580), dengan nilai prevalens ratio 0,849 berarti mahasiswa yang mengonsumsi makanan cepat saji ? 3x/minggu memiliki risiko 0,849 kali lebih besar untuk terkena obesitas dibandingkan dengan mahasiswa yang mengonsumsi makanan cepat saji < 3x/minggu.
Asupan Vitamin D Mahasiswa Fakultas Kedokteran Universitas Tarumanagara Di Masa Pandemi COVID-19 Berliani, Kristin Nadia; Frisca, Frisca
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Coronavirus disease (COVID-19) adalah penyakit infeksius yang disebabkan oleh virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) yang menyerang organ pernapasan. Sejak COVID-19 masuk ke Indonesia, dan kemudian ditetapkan sebagai pandemi oleh World Health Organization (WHO), berbagai upaya pencegahan dilakukan agar tidak tertular penyakit tersebut, seperti mencuci tangan, menggunakan masker, menjaga jarak, serta menjaga kesehatan tubuh dengan meningkatkan imunitas tubuh. Vitamin D merupakan vitamin yang akhir-akhir ini banyak diteliti karena perannya dalam imunitas. Beberapa penelitian mengungkapkan bahwa asupan vitamin D dapat menurunkan insiden, keparahan, dan risiko kematian akibat COVID-19. Penelitian ini bertujuan untuk mengetahui gambaran asupan vitamin D mahasiswa Fakultas Kedokteran Universitas Tarumanagara di masa pandemi COVID-19. Penelitian ini adalah penelitian deskriptif dengan desain penelitian cross sectional. Didapatkan total 108 subjek penelitian yang dilakukan dengan pengisian kuesioner Semi Quantitatives Food Frequency Questionnaire (SQ FFQ) yang dibagikan secara daring, dan diolah berdasarkan FNDDS Nutrient 2017-2018. Hasil penelitian diperoleh 78 (72.2%) responden perempuan dan 30 (27.8%) responden laki-laki, berusia 18-21 tahun, 67 (62%) responden tidak memiiliki kebiasaan makan suplemen multivitamin, dan 82 (75.9%) responden tidak memiliki kebiasaaan berjemur. Dari total 108 (100%) responden, didapatkan sebanyak 103 (95.4%) responden tidak mencukupi asupan vitamin D-nya dengan mayoritas berjenis kelamin perempuan yaitu sebanyak 76 (73.8%) orang, 64 (62.1%) orang tidak memiliki kebiasaan konsumsi suplemen, dan 80 (77.7%) orang tidak memiliki kebiasaan berjemur.
PENYULUHAN DAN DETEKSI DINI HIPERTRIGLISERIDEMIA DAN DAMPAKNYA TERHADAP KEJADIAN DEMENSIA Frisca, Frisca; Santoso, Alexander Halim; Satyanegara, William Gilbert; Kurniawan, Joshua; Nathaniel, Fernando; Warsito, Jonathan Hadi; Averina, Friliesa; Syachputri, Rifi Nathaznya; Amimah, Ranindita Maulya Ismah
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 6 (2023): Volume 4 Nomor 6 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i6.20841

Abstract

Demensia merupakan suatu kondisi dimana terjadi penurunan fungsi kognitif, yang berdampak pada memori, prilaku yang dapat menurunkan kualitas hidup seseorang. Jumlah penderita demensia setiap tahunya terus bertambah, dan diperkirakan akan mencapai 152 juta pada tahun 2050. Pertambahan usia merupakan faktor risiko utama pada demensia, namun faktor lain seperti gaya hidup, obesitas, depresi, inaktivitas kognitif ikut memengaruhi. Dengan berkembangnya ilmu pengetahuan, hipertrigliseridemia tidak hanya menjadi faktor risiko kardiovaskular tetapi juga demensia. Pentingnya untuk memberikan edukasi mengenai hipertrigliseridemia serta dampaknya pada masyarakat. Kegiatan penyuluhan deteksi dini dilakukan di Panti Wreda St. Anna, dengan 31 responden yang mengikuti kegiatan tersebut. Terdapat 14 responden yang mengalami ganggan kognitif, dan 13 responden memiliki nilai trigliserida yang tinggi. Masyarakat penting untuk mengetahui pengendalian dan pencegahan trigliserida tinggi serta melakukan deteksi dini melalui pemeriksaan trigliserida di fasilitas kesehatan. Hal ini penting diketahui agar masyarat terhindar dari komplikasi yang timbul dari hipertrigliseridemia ini. Diharapkan pemberikan edukasi dan deteksi dini mengenai demensia dan hipertrigliseridemia dapat meningkatkan kualitas hidup dan meningkatan kesehatan masyarakat.
Kegiatan Pengabdian Masyarakat Dalam Rangka Penapisan Kadar Protein Dan Profil Lipid Terhadap Sarkopenia Pada Kelompok Lanjut Usia Frisca Frisca; Alexander Halim Santoso; Farell Christian Gunaidi; Edwin Destra; Vincent Aditya Budi Hartono; Kanaya Fide Kusuma; Alicia Herdiman
Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia Vol. 3 No. 4 (2024): Desember: Jurnal Pelayanan dan Pengabdian Masyarakat Indonesia
Publisher : Sekolah Tinggi Ilmu Administrasi Yappi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jppmi.v3i4.1581

Abstract

The risk of sarcopenia and metabolic complications in the elderly can be caused by the aging process and decreased muscle mass in the elderly group. Sarcopenia and obesity in the elderly also increase the risk of cardiovascular disease, diabetes, and physical disability, which have the potential to reduce quality of life and increase morbidity and mortality. The purpose of this community service activity is to screen protein levels and lipid profiles in the elderly group in order to detect the risk of sarcopenia and dyslipidemia early. This activity is carried out using the Plan-Do-Check-Action (PDCA) method which includes planning, implementation, supervision, and follow-up. The community service activity was carried out at Panti Bina Bhakti, South Tangerang, involving 93 elderly participants aged >65 years. The results of the activity showed that 35 people (37.63%), 9 people (9.68%), 35 people (37.63%), and 7 people (7.53%) each had abnormal lipid profiles for HDL, Cholesterol, LDL, and Triglycerides. While 24 people (25.81%) had abnormal albumin levels. Therefore, it is necessary to monitor protein levels and lipid profiles regularly as well as early intervention through a healthy diet, regular exercise, and education for the elderly to maintain muscle mass and muscle strength.
The Correlation Between Body Composition and Mini Nutritional Assessment in The Elderly: A Cross-Sectional Study Frisca, Frisca; Santoso, Alexander Halim; Setiawan, Fiona Valencia; Rayhan, Naufal; Sukianto, Louise Audrey
Jurnal Kesehatan Amanah Vol. 9 No. 1 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i1.838

Abstract

Aging leads to changes in body composition influenced by physical, psychological, and social factors. Understanding the relationship between fat distribution and nutritional status, particularly in older adults, is crucial for targeted interventions. This study examines the impact of body fat composition on nutritional assessment, particularly its influence on MNA scores in older adults. It aims to provide insights into how fat distribution and related metabolic changes affect nutritional status and inform targeted interventions for aging populations. The sample consisted of 31 elderly woman subjects selected through purposive sampling in a cross-sectional design from St. Francis of Assisi Catholic Church. Their nutritional status was determined using the MNA score, and the body composition measures were total body fat and skeletal muscle measured by the Omron Karada Scan HBF 375. SPSS analyzed statistical differences between body composition and MNA scores. This study found significant correlations between the Mini Nutritional Assessment scores and body composition parameters, including BMI (r = 0.473, p = 0.007), total subcutaneous fat (r = 0.468, p = 0.008), and visceral fat (r = 0.457, p = 0.010). Arm skeletal muscle showed a negative correlation (r = -0.486, p = 0.006). These results emphasize that fat composition is a critical determinant of nutritional status in the elderly. The study found a significant correlation between fat composition as a key determinant of nutritional status in the elderly, with significant correlations observed between MNA scores and various body fat parameters. Keywords: Body Composition, Elderly, Mini Nutritional Assessment
The Analysis of the Role & Obligations of Notaries in Protecting Data Security Based on the Personal Data Protection Law Frisca, Frisca; Gunadi, Ariawan
Jurnal Daulat Hukum Vol 8, No 2 (2025): June 2025
Publisher : Magister of Law, Faculty of Law, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/jdh.v8i2.45098

Abstract

Notaries as public officials who are authorized to make authentic deeds carry out their duties and authorities inseparable from the processing of Personal Data, both physical and electronic. Notaries process Personal Data not only for Personal Data subjects, namely Clients, but also for workers or interns, or third parties whose information is provided by the Client. Since the enactment of the PDP Law, Notaries as officials who make authentic deeds in processing Personal Data are not only obliged to maintain the confidentiality of Personal Data, but there are also several other obligations regulated in the PDP Law as an effort to prevent and eradicate potential cybercrime. In this study, the author will dissect the role and obligations of Notaries in the security of Personal Data based on the PDP Law. The study used a normative legal method with a statutory approach and a conceptual approach. Through this study, it is concluded that a Notary as an official who makes authentic deeds has a crucial role, namely as a Personal Data Controller who can determine the purpose and method of processing personal data. Notaries have several obligations as regulated in the PDP Law, including having a basis for processing, ensuring the security of personal data, assessing the impact of Personal Data Protection, recording all personal data processing activities, appointing Personal Data Protection officials, fulfilling the rights of personal data subjects, and others. The ultimate goal of this study is expected to provide knowledge and legal certainty related to Personal Data Protection in notarial practice.
Penapisan Kadar Kolesterol Total dan HDL sebagai Upaya Pencegahan Gangguan Lipid dan Penyakit Kardiovaskular di Kelurahan Tanjung Duren Selatan Frisca Frisca; Santoso, Alexander Halim; Destra, Edwin; Pranata, Catherine Christiana; Ramadhani, Kenzie Rafif; Alwini, Muhammad Rifat Umar
Jurnal Pengabdian Masyarakat Nian Tana Vol. 3 No. 3 (2025): Juli: JPMNT : JURNAL PENGABDIAN MASYARAKAT NIAN TANA
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/jpmnt.v3i3.918

Abstract

Imbalance of body lipid levels, especially total cholesterol and HDL, is a major risk factor for cardiovascular disorders. A simple lipid profile examination can be used to detect potential atherogenic dyslipidemia that has not shown clinical symptoms. Total cholesterol and HDL levels were examined in 104 participants using the Point-of-Care Testing (POCT) technique. Education was provided individually using leaflets, which contained information on the effects of saturated fat and trans fat consumption, and the importance of unsaturated fat and fiber intake on lipid profiles. Most participants had total cholesterol levels within normal limits. However, more than half of the population showed low to very low HDL levels, indicating hidden metabolic risks. Dietary education was provided in a targeted manner according to the results of each participant's examination. Total cholesterol and HDL examinations were used to assess the risk of lipid disorders early on. Nutrition education based on examination results is useful in raising awareness of the importance of regulating diet to reduce the risk of atherosclerosis and cardiovascular complications.
Co-Authors Alexander Halim Santoso Alicia Herdiman Alwini, Muhammad Rifat Umar Amimah, Ranindita Maulya Ismah Ariawan Gunadi Averina, Friliesa Berliani, Kristin Nadia Caroline T. Sardjono Destra, Edwin Edwin Destra Farell Christian Gunaidi Ferry Sandra Gunaidi, Farell Christian Gwendy Aniko Kanaya Fide Kusuma Karjadidjaja, Idawati Kurniawan, Joshua Melina Setiawan Nathaniel, Fernando Pranata, Catherine Christiana Ramadhani, Kenzie Rafif Rayhan, Naufal San Murdoko, Ilham Wicaksono Santoso, Alexander Halim Sarijuwita, Alicia Satyanegara, William Gilbert Setiawan, Fiona Valencia Sukianto, Louise Audrey Suros, Angel Sharon Syachputri, Rifi Nathaznya Syarifah, Andini Ghina Vincent Aditya Budi Hartono Virgi Saputra Warsito, Jonathan Hadi Yohanes Firmansyah