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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Indonesian Journal of Biotechnology Journal of Agromedicine and Medical Sciences Majalah Kedokteran Sriwijaya Syntax Literate: Jurnal Ilmiah Indonesia SRIWIJAYA JOURNAL OF MEDICINE Jurnal Entomologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Community Development Journal: Jurnal Pengabdian Masyarakat Indonesian Journal of Global Health research Bioscientia Medicina : Journal of Biomedicine and Translational Research Arkus Conferences of Medical Sciences Dies Natalis Jurnal Ilmu Kesehatan Masyarakat Jurnal Farmasi Galenika
Dwi Handayani
Department Of Parasitology, Faculty Of Medicine, Universitas Sriwijaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Activity of Cytochrome P450 Monooxygenase (CYPs) Metabolic Enzymes as Markers of Insecticide Resistance in Anopheles vagus Muara Enim Mosquitoes, Indonesia Dalilah; Muhaimin Ramdja; Dwi Handayani; Lasbudi P Ambarita; R. Irpan Pahlepi; Ahmad Ghiffari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 4 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i4.222

Abstract

The use of synthetic pyrethroids in insecticide-treated bed nets (LLINs) and spray form (IRS) has been carried out since 2012 in Muara Emil Village and since 2016 in all villages in Tanjung Agung District, Muara Enim Regency. Biochemical resistance can occur to the enzymes that play a role in detoxifying the insecticide. This study aims to identify whether there is an increase in the levels of the enzyme Cytochrome P450 monooxygenase (CYPs) through the enzyme biochemical test on the malaria vector mosquito Anopheles vagus originating from Pagar Dewa Village and Muara Emil Village, Muara Enim Regency. The sample of female Anopheles mosquitoes was not full. Blood was taken at night using the resting collection method. Mosquitoes that have been identified as Anopheles vagus species are used to check CYPs enzyme levels using the ELISA method. The results of the biochemical test showed that enzyme levels increased from the Muara emil and Pagar Dewa village mosquitoes with a percentage of 71% and 61.53% (with cut off point OD> 0.165). The value of CYPs enzyme levels for mosquitoes from Muara Emil village was higher than that of the mosquitoes from Pagar Dewa Village (mean 0.005027 ± 0.007). The increased activity of the CYPs enzyme plays a role in the detoxification of synthetic pyrethroid insecticides that can cause resistance. The high levels of enzymes from the villages of Muara Emil and Desa Farah Dewa are in line with intensive insecticide exposure in eradicating malaria vectors in the highest malaria transmission areas in Muara Enim Regency.
Philogenetic Analysis of S. Scabiei Var. Hominis, Var. Cuniculi, and Var. Marmoota Gita Dwi Prasasty; Miftahurrizqiyah; Dalilah; Dwi Handayani; Tia Sabrina; Ahmad Ghiffari; Inda Astri Aryani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 10 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i10.352

Abstract

Introduction: Based on data from the 2017 Global Burden of Disease, it is known that Indonesia is the country with the highest number of scabies incidences out of 195 countries in the world. In addition to humans, scabies is also an infectious disease in mammals with a prevalence of 300 million infestations every year, even in animals the mortality rate from scabies is very high. Until now, it is still unclear whether there is a cross-infestation between human and animal scabies. Morphologically, S. scabiei between variants cannot be distinguished, while research on genetic variation is still not much done. Therefore, it is necessary to conduct studies to enrich genetic information and phylogenetic analysis. Methods: The samples tested were positive PCR results for ITS 2 and CO 1 genes, each on five amplicons, namely three S. scabiei var. hominis, one var. cuniculi, and one var. marmoota. Phylogenetics were arranged based on the closeness of the base arrangement in variants and geographically available in NCBI. Results: Of the five sample isolates studied, the ITS 2 gene amplicon is located in the 417bp band and the phylogenetic analysis of its sequencing has two branches that are unable to distinguish var. hominis and var. animalia. The CO1 gene has electrophoretic results at 317 bp as well as phylogenetic analysis results that specifically divide branches between var. hominis and var. animalia. Conclusion: S. scabiei var. hominis and var. marmoota, and var. cuniculi are distinct species and are host monospecific.
Contamination of Soil Transmitted Helminths (STH) Eggs in Raw Vegetables at Street Food Stalls and Restaurant in Lorok Pakjo Village, Palembang Leo Medianto Faziqin; Dalilah; Dwi Handayani; Chairil Anwar; Susilawati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 6 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i6.397

Abstract

Background: Infection Soil Transmitted Helminths (STH) is a disease that is a problem in the world, especially in areas with a tropical climate like Indonesia. This infection can be transmitted through consumption of raw vegetables contaminated with STH. This study aims to determine whether there is contamination of STH eggs in raw vegetables at street food stalls and restaurants in Lorok Pakjo Village, Palembang. Methods: This research is a descriptive observational study. Samples in the form of fresh vegetables were collected from 18 street stalls and 14 restaurants in Lorok Pakjo Village, Palembang. Samples were examined using the sedimentation method and observed using a microscope. Results: The results obtained 80 samples consisting of 30 cabbage, 18 basil, 30 cucumber, 1 lettuce, and 1 eggplant. Of the 80 samples, there were 20 (25%) positive samples contaminated with STH eggs consisting of 8 (10%) cabbage samples, 8 (10%) basil samples, 4 (5%) cucumber samples, and no STH contamination was found in lettuce. and eggplant. Of the 20 positive samples of STH contamination, 12 samples came from street vendors consisting of 5 (10.6%) cabbage samples, 6 (12.8%) basil samples, and 1 (2.1%) cucumber samples. While the other 8 samples came from restaurants consisting of 3 (9.1%) cabbage samples, 2 (6%) basil samples, and 3 (9.1%) cucumber samples. Found only eggs of Ascaris lumbricoides infertile decorticate in all samples consisting of 9 eggs on cabbage, 16 eggs on basil, and five eggs on cucumber. Conclusion: There is contamination of eggs Soil Transmitted Helminths in raw vegetables in street food stalls and restaurants in Lorok Pakjo Village, Palembang.
Correlation between the Use of Shared Goods with Pediculosis Capitis among Students in Pondok Pesantren Subulussalam Palembang Rifka Purnama Sari; Dwi Handayani; Gita Dwi Prasasty; Chairil Anwar; Fatmawati Karim
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.29113

Abstract

Pediculosis capitis is a parasitic infection caused by the parasite Pediculus humanus var. capitis, which commonly found in densely crowded areas such as boarding schools. It is possible to contract pediculosis capitis by coming into direct or indirect contact with sufferers' hair. The goal of this study was to assess the prevalence of pediculosis capitis in students at Pondok Pesantren Subulussalam Palembang, as well as the association between the use of shared goods and the occurrence of pediculosis capitis. This study is a cross-sectional observational analytic study including 116 students who live permanently in Pondok Pesantren Subulussalam Palembang. A questionnaire was used to collect data, as well as direct observation of hair samples. The Chi-Square test, Fisher's exact test, and logistic regression were used to examine the results. The findings revealed that 35.3% of people had pediculosis capitis, and that there was a significant association between the use of mattresses (p=0.007), combs (p=0.024), and shared veils (p=0.006) and the occurrence of pediculosis capitis. The use of combs (p=0.018) and shared veils (p=0.001) were the most influential variables on the occurrence of pediculosis capitis, according to the results of the logistic regression test. The spread of pediculosis capitis disease is predicted to be reduced and prevented with improved personal hygiene, environment sanitation, and treatment. Keywords: Pediculosis capitis, boarding schools, Subulussalam, shared goods
Efforts to Prevent Variations of Skin Diseases in Islamic Boarding Schools through Personal Hygiene and Sanitation Education Gita Dwi Prasasty; Dwi Handayani; Dalilah; Desi Oktariana
Conferences of Medical Sciences Dies Natalis Vol. 2 No. 1 (2020): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.506 KB)

Abstract

The condition of residents and environment of the boarding school (pondok pesantren) which is not good has formed several variation of skin diseases that are repeated and almost similiar in every Islamic boarding school in Indonesia. This is a challenge for the pesantren community, health workers and academics to prevent, at least reduce the prevalence of these diseases. This activity was carried out in two stages, examination and education based on the results of the skin disease pattern that has been obtained from previous examinations. Education was performed online about diseases variation and how to cope them from the aspects of personal hygiene and environmental sanitation at the Pondok Pesantren Kampung Tauhiid Sriwijaya. This activity aimed to provide an coping of the variation of skin diseases that will be encountered by santri-santriwati and an accurate understanding of its prevention through personal hygiene and environmental sanitation.
EDUCATIONAL VIDEO RELATED TO COVID-19 AND VACCINATION FOR THE COMMUNITY Zen Hafy; Venny Larasati; Soilia Fertilita; Dwi Handayani
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.932 KB)

Abstract

One of the efforts being promoted by WHO to prevent Covid-19 is vaccination. Vaccination aims to prevent the symptoms of a disease caused by pathogenic infection. In some cases, vaccination does not prevent infection but can limit the consequences of the infection. Some of the obstacles encountered in the community include the lack of public knowledge about vaccination, a lot of negative news that develops in the community about vaccination, and the availability of vaccines for the community is still limited. Efforts to educate the public have been carried out to increase public awareness about the benefits of vaccination, either through direct counseling by agencies engaged in the health sector or through social media. Such efforts need to be carried out massively and continuously so that education can reach all levels of society. This community service activity program is carried out by producing educational videos that will target all population levels to provide information about Covid-19 management and clarifications on some most common incorrect information or even myths about Covid-19 vaccination and give the public in Indonesia a chance to learn the facts about the Covid-19 vaccine.
CENTRAL OBESITY DETECTION AND WEIGHT MANAGEMENT Gita Dwi Prasasty; Chairil Anwar; Desi Oktariana; Nia Savitri Tamzil; Evi Lusiana; Dwi Handayani
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.023 KB)

Abstract

Obesity is a multifactorial disease that occurs due to excess fat tissue that can interfere with health. It is estimated that obesity will reach more than 50% in developed countries. In Indonesia, the prevalence of obesity in people over 18 years old is 21.8%. Environment or diet is one of the causes of obesity. Community service activities were carried out on October 18, 2021, in Kuto Batu Village, Palembang, with the main target being community cadres with a minimum of 30 participants. Based on the pre-test results conducted on 32 participants, 60% already had a good knowledge of obesity and central obesity and weight management. However, unfortunately, more than half of the participants (65%) were overweight and even obese type 2, and 12% of participants were underweight, while the rest were normal. The results of the blood pressure examination showed that 62% of the participants had blood pressure greater than or equal to 130/80 mmHg. The data also showed that most of the overweight and obese participants had above-normal blood pressure. The same results in the participant's abdominal circumference as many as 62% had central obesity.
MEDICINAL PLANTS IN THE PREVENTION OF GOUT ARTHRITIS Evi Lusiana; Msy Rulan Adnindya; Nia Savitri Tamzil; Kamaluddin Kamaluddin; Dwi Handayani; Gita Dwi Prasasty; Desi Oktariana; Tia Sabrina
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.931 KB)

Abstract

The use of medicinal plants for healing is the oldest form of medicine in the world. Medicinal plants such as ginger, lemongrass, and turmeric have been clinically tested and proven effective in reducing muscle pain, stiffness, and difficulty moving the knee in patients. Medicinal plants are the types of choice that are efficacious as drugs with easy maintenance and relatively low costs. Medicinal plants are a safe alternative to family medicine because they rarely cause side effects and are easy to process and consume to prevent gout arthritis. Some efficacious herbal plants to reduce pain caused by arthritis are ginger, lemongrass, turmeric, thyme (mint), garlic, green tea, and cinnamon. These plants, based on research, have properties as anti-inflammatory or anti-inflammatory in reducing muscle pain and stiffness in gout arthritis.
Malaria Surveillance in the Anak Dalam Tribe, Jambi, Indonesia Ade Suryaman; Chairil Anwar; Dwi Handayani; Irsan Saleh; Dalillah Dalillah; Gita Dwi Prasasty; Ahmad Giffari; Sulfa Esi Warni
Jurnal Ilmu Kesehatan Masyarakat Vol. 12 No. 2 (2021): Jurnal Ilmu Kesehatan Masyarakat (JIKM)
Publisher : Association of Public Health Scholars based in Faculty of Public Health, Sriwijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.383 KB) | DOI: 10.26553/jikm.2021.12.2.104-116

Abstract

Transmission of malaria is common in countries with tropical and subtropical. In several cases, malaria presents in the sufferer especially in individuals that have never received treatment shortly. As the early phase of patient identification, screening is important as an effort to eradicate malaria, in addition to the gold standard which currently used, other diagnostic tools are needed to conduct a malaria incidence survey to obtain comparative data using 3 diagnostic tools, goal standard checks, which are currently unable to detect asymptomatic malaria. This study aims to compare three standard diagnostic test (Rapid Diagnostic Test, Giemsa, and Nested Polymerase Chain Reaction) for the measurement of malaria prevalence within the Anak Dalam Tribe community in Jambi, Indonesia. This descriptive research with a survey design was conducted on 99 persons in Anak Dalam Tribe. It was discovered that majority of the respondents were the adult age category (52.5%),were female (50.5%). The prevalence of this infectious disease as detected by Rapid Diagnostic Test, microscopy, and Nested Polymeras Chain Reaction examination were 3%, 5% and 35.3% respectively. Non-Plasmodium falciparum was detected by examining samples with Rapid Diagnostic Test, on microscope, P. vivax and P. falciparum were found, while on Nested Polymerase Chain Reaction, two bands at 120bp and 205bp showed P. vivax and P. falciparum respectively. Nested Polymeras Chain Reaction is more sensitive to detected asymptomatic malaria, however, Rapid Diagnostic Test and Giemsa sensitive with parasitemia threshold.
Risk Factors for Uterine Atony in Postpartum Hemorrhage Patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Firmansyah Basir; Hurin ‘Afina Gnd; Dwi Handayani; Hartati; Hadrians Kesuma Putra
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.719

Abstract

Background: Uterine atony can be life-threatening for a pregnant woman in labor and bleeding after delivery. It is important to explore the risk factors that can cause uterine atony in order to detect it early and take preventive measures. This study aimed to explore the risk factors for causing uterine atony in postpartum hemorrhage patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Methods: This study was an analytic observational study with a case-control approach. A total of 52 subjects (13 case group subjects and 39 control group subjects) participated in this study. Risk factor analysis was carried out with the help of SPSS version 25 in univariate and bivariate. Results: Maternal age at delivery is associated with the risk of uterine atony in postpartum hemorrhage patients. Mothers aged less than 20 years or more than 35 years are at risk of experiencing uterine atony by 5.8 times more at risk than mothers aged 20-35 years. The risk factors for parity, prolonged labor, macrosomia, gemelli, hydramnios, induction of labor, history of postpartum hemorrhage, and type of delivery were not associated with uterine atony in postpartum hemorrhage patients, p>0.05. Conclusion: The age of delivery of mothers who are less than 20 years or more than 35 years is a risk factor for uterine atony in postpartum hemorrhage patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
Co-Authors Ade Suryaman Ade Suryaman Ade Suryaman Adnindya, Msy Rulan Afiat Berbudi Ahmad Ghiffari Ahmad Giffari Anwar, Chairil Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Charil Anwar Dalilah Dalilah Dalilah Dalilah Dalilah Dalillah Dalillah Dalillah Dalillah Denny Satria Utama Desi Oktariana Desi Oktariana Desi Oktariana Dian Adhe Bianggo Naue Didid Haryanto Elly Nurachman Fadjar Siddiq Hidayatullah Fahmi, Ismail Fatmawati Firmansyah Basir Gita Dwi Prasasti Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Hadrians Kesuma Putra Hartati Herlina Herlina Hurin ‘Afina Gnd Husna Syafira Muthmainnah Inda Astri Aryani Irsan Saleh Jayawarsa, A.A. Ketut Kamaluddin Kamaluddin Kemas Muhammad Alwan Dwiputra Laida Neti Mulyani Laida Neti Mulyani Lasbudi P Ambarita Lasbudi P Ambarita Leo Medianto Faziqin Mentari Permana Putri Miftahurrizqiyah Miftahurrizqiyah Miftahurrizqiyah Muhaimin Ramdja Muhammad Irsan Saleh Nia Savitri Tamzil Nunuk Dyah Retno Lastuti Nur Fadilatunnisa R. Irpan Pahlepi Rahman Irpan Pahlepi Rifka Purnama Sari Risa Rahmadona Sarbaini Sarbaini Soilia Fertilita Sri Wiyani Sulfa Esi Warni Sulfa Esi Warni Sulfa Esi Warni Susilawati Susilawati Tia Sabrina Tia Sabrina Tia Sabrina Venny Larasati Veny Larasti Zen Hafy