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All Journal Jurnal Ilmu Lingkungan Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Jurnal Pengabdian UntukMu NegeRI Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) UMI Medical Journal Unri Conference Series: Community Engagement Dinamika Lingkungan Indonesia
Muhammad Yulis Hamidy
Fakultas Kedokteran Universitas Riau Jalan Diponegoro No. 01 Pekanbaru Riau
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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EFEK LARVASIDA EKSTRAK ETANOL DAUN PEPAYA (Carica papaya) TERHADAP LARVA Aedes aegypti Meidy Shadana; Suri Dwi Lesmana; Muhammad Yulis Hamidy
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Dengue Hemorrhagic Fever (DHF) is a dangerous viral disease because itcan cause death in a very short time. The desease is caused by dengue viral withAedes aegypti (Ae.aegypti) as the main vector. Various ways have been made toeradicate Ae.aegypti, one of which is the use of chemical larvicides. However, theuse of this chemical larvicides has adverse effects, so it is necessary to findanother alternative such using botanical larvicides. Papaya (Carica papaya) is aplant that is potentially as botanical larvicides. The aim of this research is toknow the larvicide effect etanol extract of papaya leaf (Carica papaya) againtsAe.aegypti larvae. This is an experimental research by using variousconcentration are 400ppm, 800ppm, 1000ppm, 1200ppm, 1400ppm, 1600ppm,1800ppm and a container of distilled water as a control. Test performed threerepetitions with each concentration contains of 20 larvae. The level of larvaemortality was observed after 24 hours. Analysis of the research results usingProbit regression analysis obtained LC50 945.165ppm and LC90 1495.219ppm.Keywords: Larvicide effect, Carica papaya, Aedes aegypti
Pemberdayaan masyarakat melalui pengolahan sampah anorganik menjadi barang dekoratif bernilai ekonomis Huriatul Masdar; Muhammad Yulis Hamidy; Fifia Chandra; RM Riadi; Yulia Irvani Dewi; Nurfi Pratiwi
Unri Conference Series: Community Engagement Vol 2 (2020): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.2.222-227

Abstract

Garbage is the leftover product from every human daily activity that is thrown away which, if not managed properly, can cause environmental and health problems. Waste bank is a form community participation in waste management. Air Putih Sub-dsitrict already has a waste bank that is actively operating. However its activities are still limited to collect inorganic waste from customers and sell it to collectors. In order to increase the value of inorganic waste collected in the waste bank, a training to decorate used items using decoupage technique was conducted. Waste bank managers and Empowerment Family Welfare (PKK) members were participated in this training. In addition, a training how to use social media as a marketing media were performed. The results showed that the target community's skills had been achieved in processing inorganic waste into decorative items with higher economic value. Meanwhile, the sustainability of production and the economic impact resulting from these trainings still require further evaluation.
Analisis Pengaruh Faktor Lingkungan Dan Faktor Pekerja Terhadap Kapasitas Fungsi Paru Pekerja Industri Meubel Di Kota Pekanbaru Tahun 2013 Frisca Raynel; Zulkarnaini Zulkarnaini; Yulis Hamidy
Dinamika Lingkungan Indonesia Vol 1, No 2 (2014)
Publisher : Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.028 KB) | DOI: 10.31258/dli.1.2.p.124-129

Abstract

The objectives of this research are to analyze and investigate the influence ofenvironmental factors and characteristics of workers towards lung function capacity offurniture industry workers at Pekanbaru. This study used a cross-sectional design, with totalsampling technique as much as 52 people of furniture industry workers. The result showed,there are 3 variables which affect lung function capacity of workers, that is exposure torespirable dust, smoking habit, and use of self protective tools. From the bivariate analyzes, itfound that exposure to respirable dust is the most dominant variable that affect the capacityof pulmonary function with p value: 0,000, that is equal to 41 times higher than workers withdust levels below the threshold value. 
Penerapan pengolahan telur itik dengan oven pengasapan pada UKM petani sawit di Kampung Sialang Baru, Kabupaten Siak, Riau Yusfiati Yusfiati; Rr. Sri Catur S; Siti Fatonah; M. Yulis Hamidy
Unri Conference Series: Community Engagement Vol 4 (2022): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.4.347-354

Abstract

The duck farming business can develop well by improving the management of duck eggs into smoked salted eggs of various flavors. The service activity aims to educate members of the Sialang Baru Palm Oil Farmers UKM about the use of cadling and processing smoked salted eggs with various flavors. The target community for this activity is around 15 people. The service method has three stages, namely first, making leaflets about candling and making smoked salted eggs. Second, the provision of material through socialization activities, in the form of lectures and discussions. Third, the practice of using egg candling and the practice of processing smoked salted eggs of various flavors. Evaluation by giving questionnaires before and after the lecture to participants. The results of the questionnaire were tabulated and described. The results of the dedication resulted in making salted eggs by smoking better than ordinary salted eggs. The taste of the egg texture is better and the yolk color is more yellow than ordinary salted eggs. Shorter manufacturing time is 7 days and smoking is 12 hours. The use of a smoked oven from a used drum is designed to have 3 shelves for eggs and fuel with wood husks. The people of the Sialang Baru Palm Oil UKM were very enthusiastic with the attendance of more than 70%. The counseling and practice of processing smoked salted eggs have educated the community to further develop their business in the future.
Pengaruh Ekstrak Buah Bakau (Rhizophora sp) terhadap Ekspresi Monocyte Chemoattractant Protein-1 pada Aorta Tikus Aterosklerosis Muhammad Yulis Hamidy; Huriatul Masdar; Ayu Trisya Arti
Jurnal Ilmu Kedokteran Vol 17, No 1 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i1.2023.41-45

Abstract

Atherosclerosis is an atheromatous plaque that protrudes into and clogs blood vessels. This study aimed to analyze the effect of Rhizophora sp extract on the expression of Monocyte Chemoattractant Protein-1 (MCP-1) in the early stages of atherosclerosis in rats fed an atherogenic diet. Eighteen abdominal aortic paraffin blocks of white rats were used, consisting of 3 groups: normal diet (K1), atherogenic diet (K2), and atherogenic diet and Rhizophora sp extract (K3). The effect of Rhizophora sp extract was assessed by immunohistochemical examination. MCP-1 expression was calculated in 5 fields of view, then analyzed using Photoshop Image Analysis. The results of this study indicated that administration of Rhizophora sp extract reduced MCP-1 expression in K3 compared to K2 (0.155±0.075 vs 0.246±0.097) although this result was not statistically significant. In conclusion, Rhizophora sp extract has the ability to inhibit MCP-1 expression in the aorta of rats fed an atherogenic diet.
Peningkatkan Peran Masyarakat Dalam Deteksi Dini Dan Pencegahan Penyakit Kardiovaskuler Di Wilayah Kerja Puskesmas Purnama Kota Dumai Muhammad Yulis Hamidy; Huriatul Masdar; Fifia Chandra
Jurnal Pengabdian UntukMu NegeRI Vol 7 No 2 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

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Abstract

Tingginya angka kejadian dan kematian akibat penyakit kardiovaskuler masih menjadi masalah kesehatan utama, termasuk di Kota Dumai. Kader posyandu sebagai perpanjangan tangan pemerintah sangat berperan dalam membantu mendeteksi dini adanya risiko penyakit kardiovaskuler ini. Tujuan dari kegiatan pengabdian kepada masyrakat ini adalah untuk meningkatkan pengetahuan dan keterampilan kader posyandu dalam melakukan deteksi dini serta memberikan edukasi kepada masyarakat tentang pencegahan risiko terjadinya penyakit kardiovaskuler. Kegiatan ini dilaksanakan dalam bentuk ceramah dan pelatihan keterampilan pengukuran antropometri dan tekanan darah dengan melibatkan 20 orang kader posyandu lansia yang ada di wilayah kerja Puskesmas Purnama Kota Dumai. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan kader mengenai penyakit kardiovaskuler, risiko serta pencegahannya. Selain itu, keterampilan kader dalam melakukan pengukuran antropometri dan interpretasinya serta melakukan pengukuran tekanan darah juga sudah baik. Dengan demikian diharapkan setelah pelatihan ini kader sudah mampu melakukan deteksi dini adanya risiko penyakit kardiovaskuler pada masyarakat setempat.
Ketebalan Tunika Media Aorta Tikus Aterosklerosis Pasca Pemberian Ekstrak Buah Bakau (Rhizophora sp) Muhammad Yulis Hamidy; Huriatul Masdar; Adham Alfian
Jurnal Ilmu Kedokteran Vol 17, No 2 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i2.2023.117-120

Abstract

Atherosclerosis is a multifocal immunoinflammatory disease of medium and large arteries stimulated by lipids, endothelial cells, leukocytes and intima smooth muscle cells. One of the markers of atherosclerosis is thickening of the tunica media. The administration of antioxidants is expected to inhibit the occurrence of atherosclerosis. Mangrove (Rhizophora sp) is one of plants with a high source of antioxidants. The objective of this study was to analyze the effect of mangrove (Rhizophora sp) fruit extract on the thickness of aortic tunica media of atherosclerotic rats. A total of eighteen rats were used in this study, divided into 3 groups. Group A (standard control) is a group of rats that received a standard diet. Group B (positive control) is a group of rats that received a high cholesterol diet for 3 days. Group C (treatment group), apart from receiving a high cholesterol diet, was also given Rhizophora sp fruit extract at a dose 500 mg/kg b.w/day orally for 3 days. The effect of mangrove (Rhizophora sp) fruit extract on the thickness of the aortic tunica media was evaluated by a histological procedure using the Leica application. This study shows that the thickness of aortic tunica media is higher in the group receiving a high cholesterol diet than the standard control group (0.096 vs. 0.079; P=0.036). The group that received mangrove (Rhizophora sp) fruit extract had relatively the same thickness as the standard group (0.080 vs. 0.079; P=0.999). As the conclusion, Mangrove (Rhizophora sp) fruit extract may inhibit thickening of the aortic tunica media in atherosclerotic rats.
Farmakogenomik Metabolisme Obat: Menelusuri Variasi Genetik dan Dampaknya terhadap Respon terhadap Obat Syaifulanwar, Alauddin; Ghifari, Annisa Abdi; Hamidy, Muhammad Yulis
UMI Medical Journal Vol 10 No 1 (2025): UMI Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v10i1.371

Abstract

Latar belakang: Farmakogenomik merupakan studi bagaimana susunan genetic memengaruhi responsnya terhadap pengobatan yang dapat menyebabkan variasi respons pengobatan. Farmakogenomik bertujuan untuk mengoptimalkan efektivitas pengobatan sekaligus meminimalkan reaksi obat yang merugikan. Namun, terdapat tantangan yang menghambat seperti keterjangkauan uji genetik, infrastruktur, seta edukasi bagi tenaga kesehatan. Isi: Farmakogenomik menawarkan peluang besar dalam personalisasi terapi untuk penyakit kronis seperti gangguan psikiatri. Profiling genetic terhadap varian enzim cytochrome seperti CYP2C19 dan CYP2D6 telah terbukti meningkatkan pemilihan dan penyesuaian dosis obat, sehingga dapat menurunkan risiko efek samping. Pedoman klinis dari Clinical Pharmacogenetis Implementastion Consortium (CPIC) semakin memfasilitasi penerjemahan riset farmakogenomik ke dalam praktik klinis yang aplikatif, dengan menyediakan kerangka kerja terstruktur untuk integrasi data genetic dalam layanan kesehatan. Kesimpulan: Integrasi farmakogenomik ke dalam praktik klinis rutin menawarkan pendekatan yang transformatif dalam layanan kesehatan, dengan potensi untuk memperbaiki hasil terapeutik secara global.
Mangrove (Rhizophora sp.) Fruit Extract Inhibits Tumor Growth Factor (TGF)-β1 Expression in High Cholesterol Diet-Fed Rats: Ekstrak Buah Bakau (Rhizophora sp.) Menghambat Ekspresi Tumor Growth Factor(TGF)-β1 pada Tikus yang Mendapat Diet Tinggi Kolesterol Hamidy, Muhammad Yulis; Masdar, Huriatul; Winarto, Winarto
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15667

Abstract

Background: Atherosclerosis is a major finding in cardiovascular disease. One of the pro-fibrotic cytokines that play an important role in the atherosclerosis process is Tumor Growth Factor (TGF)-β1, where the presence of high TGF-β1 secretion due to hypercholesterolemia will trigger excessive collagen matrix formation. Objective: To analyze Rhizophora sp fruit extract effect on TGF-β1 expression in high cholesterol diet-fed rats. Material and Methods: Eighteen 10-week-old rats weighing 150-200 g were used in this study. These animals were grouped into 3 groups, each consisting of 6 rats. Group A (normal control) is a group of rats that received a normal diet. Group B (atherogenic control) received a diet that induces atherosclerosis (atherogenic diet). This diet contains 2% cholesterol, 5% goat fat, 0.2% cholic acid and standard diet up to 100%. Atherogenic diet was given for 3 days, and on the first day this group also received vitamin D3 700,000 IU/kg. Group C (treated), apart from receiving an atherogenic diet, was also given Rhizophora sp fruit extract 500 mg/kg body weight. The Rhizophora sp fruit extract effect on TGF-β1 expression was evaluated by immunohistochemical procedure. The area of ​​the expression is calculated using the ImageJ. Results: The results of this study indicate that the expression of TGF-β1 is higher in the group receiving the atherogenic diet than the normal control group (17.3 vs. 8.9; P=0.000). Rhizophora sp fruit extract reduced this expression remarkably (17.3 vs. 11.4; P=0.001). Conclusion: Rhizophora sp fruit extract inhibits the the expression of TGF-β1 in high cholesterol diet-fed rats.
Sosialisasi Penerapan Eeg Candling Dan Pembuatan Telur Asin Asap Pada kelompok Tani Sawit Kampung Sialang Baru, Kabupaten Siak Yusfiati; Fatonah , Siti; Setyaningsih, Sri Catur; Hamidy, Muhammad Yulis
Jurnal Pengabdian UntukMu NegeRI Vol. 7 No. 1 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v7i1.4136

Abstract

Teknologi yang dapat membantu edukasi peternak Desa Sialang Baru yang dapat menjadi usaha ternak itik adalah peningkatan pengelolaan telur itik menjadi telur asin dengan berbagai rasa dan pembuatannya dengan teknologi asap cair. Kegiatan pengabdian bertujuan mengedukasi anggota UMKM petani Sawit Sialang Baru tentang pemanfaatan egg cadling untuk membantu proses penetasan telur itik dan pengolahan telur asin dengan asap cair yang memiliki beraneka macam rasa. Masyarakat sasaran berjumlah berkisar 15 orang. Metode pengabdian digunakan ada dua tahap, yaitu pertama, pembagian leaflet tentang manfaat dan cara menggunakan Egg candling dan pembuatan telur asin dengan asap cair. Kedua, pemberian materi dan praktek penggunaan egg candling dan pembuatan telur asin dengan pengasapan melalui kegiatan sosialisasi, berupa ceramah dan diskusi.Evaluasi pemahaman penyuluhan penggelolaan teknologi egg candling dan pengasapan cair pada telur itik dengan memberikan angket sebelum dan sesudah ceramah kepada semua peserta penyuluhan. Hasil angket ditabulasi dan dideskripsikan.Hasil yang didapatkan setelah penyuluhan yaitu sangat baik terhadap pengetahuan peserta terhadap materi yang diberikan dibandingkan sebelum penyuluhan. Materi yang disampaikan telah mengedukasi kelompok tani Sawit dalam pengembangan usaha mereka dimasa akan datang.
Co-Authors Adham Alfian Adhisti Handarie Agung Aminatul Fitri Annisa Abdi Ghifari Ayu Trisya Arti Darmawi Dedi Afandi Devi Risma Diva Yurian Dwika Eliza Fitria Fatonah , Siti Fellyana Putri Fifia Chandra Fifia Chandra Firni Dwi Sari Frisca Raynel Huriatul Masdar Huriatul Masdar I Gusti Wayan Murjana Yasa Inayah " INDRA YOVI Laksono Trisnantoro M. Imam Muttaqien, M. Imam Meidy Shadana Mia Rizki Awalia Nurfi Pratiwi NURUL AZIZAH Qurratul Aini RM Riadi Rr. Sri Catur S Ruza Prima Rustam, Ruza Prima Setyaningsih, Sri Catur Siti Fatonah Suri Dwi Lesmana Syaifulanwar, Alauddin Winarto Winarto Wirawan Adikusuma Yulia Irvani Dewi Yullya Tri Utari Yusfiati Yusfiati Yusfiati Zuhirman " Zulfan Saam Zulharman "