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Analisis Jalur: Gangguan Fungsi Nefron Tikus (Rattus Norvegicus) Akibat Mengkonsumsi Partikel Mikroplastik Polietilena: Pathway Analysis: Disorders of Nephron Function in Rats (Rattus Norvegicus) Due to Intake of Polyethylene Microplastic Particles Yudhiakuari Sincihu; Mujib Hannan; Niluh Suwasanti; Laura Wihanto; Nita Kurniawati; Dewa Ayu Liona Dewi; Steven; Sianty Dewi; Ari Christy Mulyono; Irene Lingkan Parengkuan; Henry Ricardo Handoyo; FX Himawan Jong; Andre Young; Alvin Julian; Angeline Rivia Simanjuntak; Marion Florentia
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 7 No. 1 (2024)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v7i1.4240

Abstract

Latar belakang: Pencemaran plastik menjadi isu kesehatan saat ini. Partikel plastik berukuran mikron (MPs) dapat mengganggu kesehatan karena terkonsumsi secara tidak sengaja oleh mahluk hidup dan masuk kedalam rantai makanan manusia. Polietilena salah satu polimer plastik yang banyak mengkontaminasi makanan manusia. Partikel plastik yang terabsorbsi akan mengalami persisten dan bioakumulasi dalam darah. Partikel ini mengandung bahan toksik sehingga menimbulkan reaksi oksidasi pada komponen biologi, salah satunya low-density lipoprotein (LDL). Ox-LDL menyebabkan kerusakan pertahanan nefron sehingga memicu kaskade kerusakan. Indikator kerusakan fungsi nefron ginjal berupa serum albumin, blood urea nitrogen, dan serum kreatinin. Tujuan: Menjelaskan mekanisme gangguan fungsi nefron akibat mengkonsumsi partikel MPs polietilena. Metode: Penelitian eksperimental murni pada 42 ekor tikus (Rattus norvegicus) yang dikelompok secara random menjadi 6 kelompok. Desain penelitian adalah post-test only control group. Dosis paparan yakni 0mg; 0,0375mg; 0,075mg; 0,15mg, 0,3mg, 0,6mg partikel MPs per hari diberikan secara berurutan pada setiap kelompok. Pemberian bahan MPs menggunakan sonde oral selama 90 hari. Data di analisis menggunakan program Smart-PLS untuk membuat model mekanisme gangguan fungsi nefron akibat mengkonsumsi partikel MPs. Hasil: Paparan peroral partikel MPs pada tikus secara signifikan meningkatkan kadar partikel MPs dalam darah dan Ox-LDL darah. Keberadaan MPs dalam darah juga akan meningkatkan Ox-LDL darah, selain itu menurunkan kadar serum albumin, meningkatkan kadar blood urea nitrogen dan serum kreatinin darah. Sedangkan peningkatan Ox-LDL hanya berkontribusi terhadap terjadinya penurunan kadar serum albumin dan peningkatan kadar blood urea nitrogen darah (semua nilai T-stat > 1,96). Kesimpulan: Mengkonsumsi partikel MPs dapat menyebabkan gangguan fungsi nefron pada tikus.
Learning Culture from the Perspective of the Successful Indonesian Nurse Competency Examination Hidayat, Syaifurrahman; Hannan, Mujib; Huzaimah, Nailiy; Suprayitno, Emdat; Mumpuningtias, Elyk Dwi; Putri, Prestasianita; Wijayanti, Agnes Erida; Manuel da Silva, Adão
IJNP (Indonesian Journal of Nursing Practices) Vol. 8 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ijnp.v8i2.22426

Abstract

Background: The Indonesian Nurse Competency Examination (INCE) is a strategic component that determines the output of nursing graduate students. The varied geographical conditions of the various islands in Indonesia can influence access and quality of education, causing students to have a more inclusive perspective. The learning culture of Indonesian nursing students is unique and generally carries over to higher education, notably nursing profession education.Objective: The purpose of the study is to explain the learning culture model from the perspective of the success of the nurse competency examination and the relationship between learning culture and the success of the nurse competency examination.Methods: A qualitative and quantitative combination research (mixed method) with a sequential-exploratory design was employed. Stage 1 used descriptive qualitative methods. While data collecting used structured interviews, the sampling technique utilized snowball with (n=9), and data analysis used Sandelowski content analysis. Stage 2 was an observational analytical design with a retrospective approach involving 74 nursing students at Wiraraja University who lived in the Indonesian student area. Data analysis then employed the Structural Equation Model (SEM) test to find variables that significantly influence the success of INCE.Results: Stage-1 produced three themes: Theme-1: background of the learning environment concerning facilities utilization and searching strategy for learning resources; Theme-2: learning activities including learning styles, learning motivation, and self-confidence and abilities; Theme-3: learning habits comprising learning methods, concentration, and repeating the learning material. In stage 2, the result revealed that learning environment background (p=0.031), learning activities (p=0.021), and study habits (p=0.028) were significantly related to the success of the INCE on students.Conclusion: The learning culture of Indonesian students from the perspective of success in the INCE is formed starting from the pre-graduate level and continuing at the higher and professional levels.
Evaluating the Role of Perceived Benefits and Self-Efficacy in Enhancing Foundational Capabilities, Power Components, and Self-Care Operations Among Patients with Type 2 Diabetes Mellitus Hannan, Mujib; Akbar, Ilham; Dwi Mumpuningtias, Elyk; Hidayat, Syaifurrahman; Suprayitno, Emdat
IJNP (Indonesian Journal of Nursing Practices) Vol. 9 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ijnp.v9i2.25984

Abstract

Introduction: The management of type 2 diabetes is largely shaped by how patients perceive the advantages of their treatment and their confidence in their ability to manage the condition. Optimal disease management requires adequate foundational capabilities, enabling power components, and the capacity to perform effective self-care practices. This research examines how perceived benefits and self-efficacy influence foundational capabilities, power components, and self-care agency among Patients diagnosed with type 2 diabetes in Sumenep Regency, Madura. Method:  This study employed a cross-sectional design, implemented in Bluto District, Sumenep Regency, from April to May 2024. Data were collected from a sample of 534 Patients diagnosed with type 2 diabetes. The research sample consisted of 120 people using a proportional random sampling technique. The influence among variables was analyzed using SmartPLS Structural Equation Modeling (SEM).    Results: The findings revealed that the perceived benefit factor affects the foundational capabilities of patients with a P-value of 0.000 (<0.05), affects the ability of power components of patients with a P-value of 0.000 (<0.05), and affects the ability to perform self-care operations of patients with a P-value of 0.041 (<0.05). In addition, the perceived self-efficacy factor affects the ability to perform self-care operations, with a P-value of 0.008 (<0.05). Perceived benefits and perceived self-efficacy play essential roles in improving the ability to perform self-care, and perceived benefits are significant in improving the ability to independently manage foundational capabilities and power components in type 2 diabetes mellitus. Conclusion: Perceived benefits and self-efficacy highlight the need for stronger patient education and skill-building to improve diabetes self-care. Tailored training and continuous support can enhance patients’ confidence and ability to manage their condition. Integrating behavioral strategies and involving patients in decision-making can also further strengthen independent diabetes control.
Co-Authors Abd Wahid Abd Wahid Abd Wahid Abdul Muhith Abdul Muhith Abdul Muhith Muhith Akhmad Feri Fatoni Akhmad Feri Fatoni Alfi Laila Alvin Julian Andre Young Angeline Rivia Simanjuntak Apriyani Puji Hastuti Ari Christy Mulyono Chindy, Leviana Dea Chindy, Leviana Dea Citra Astri Aqnata Cory Nelia Damayanti Cory Nelia Damayanti Cory Nelia Damayanti Dewa Ayu Liona Dewi Dian Ika Puspitasari Dian Permatasari Dian Permatasari Dwi Helynarti S Dwi Mumpuningtias, Elyk Ebit Abidillah Eka Meiri Kurniyati Eka Puspitasari, Dian Eko Mulyadi Elyk Dwi Mumpuningtias Emdat Suprayitno Emdat Suprayitno Emdat Suprayitno Emdat Suprayitno Erly Wahyuni Erlyn Wahyuni Eva Nurhidayati FX Himawan Jong Handoyo, Henry Ricardo Hesti Yuliyana Ilham Akbar Irene Lingkan Parengkuan Ismawati S S Iva Gamar Dian Pratiwi Jeni Moudy Pujianti Lantin Sulistyorini Laura Wihanto Lutfi K M Himawan S Manuel da Silva, Adão Maria Fernandes Amaral, Manuela Marion Florentia Mayank Nirmala Sandi Mayank Nirmala Sandi Muhammad Rochman Muhammad Rochman, Muhammad Nailiy Huzaimah Nailiy Huzaimah Nailiy Huzaimah Nelia, Cory Nelyta Oktavianisya Nelyta Oktavianisya Niluh Suwasanti Nita Kurniawati Nur Aini Fahmiah Nurul Mawaddah Prameswari, Hellen Nindya Prestasianita Putri Rabbaniyah Hariyati Hidayah Ratna Indriyani Rochim, Nur Laily Rohmaningsih, Ida Sandu Siyoto Sianty Dewi Silvia Ratna Sari Dewi Soares, Domingos Sri Sumarni Steven Su&#039;udiyah Su&#039;udiyah Su'udiyah Su'udiyah Sugesti Aliftitah Suraying Suraying Suraying, Suraying Suudiyah, Suudiyah Syaifurrahman Hidayat Tatik Sutarti Tatik Sutarti tiyah, khomariyatul kip Ummi Afifah Wijayanti, Agnes Erida Yudhiakuari Sincihu Yulia Wardita Yulia Wardita Zakiyah Yasin