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The Effect of Adsorbents on the Quality of Refined Eel Fish (Anguilla marmorata [Q.] Gaimard) Oil as a Raw Material for Pharmaceutical Preparations Jamaluddin; Yuliet; Wa Ode S. Musnina; Yonelian Yuyun; Syahna Shaldan; S. Malasugi; Putri A. Arta; Gina N. Putri; Adetya Maryani; Muhammad F. Haq; Syamsul Lakahoro; Nurul Awwaliyah P. Firman; Siti B. Al-Amri; Sinta Amelia; Asriani Hasanuddin; Novalina Serdiati; Jusri Nilawati
Jurnal Penelitian Pendidikan IPA Vol 10 No 12 (2024): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i12.9806

Abstract

Eel fish (Anguilla marmorata (Q.) Gaimard) oil is a valuable source of health-promoting unsaturated fatty acids. Adsorbent selection during the bleaching stage of fish oil purification can significantly impact the final product quality.  This study aimed to evaluate the impact of different adsorbents on the quality of refined eel fish (Anguilla marmorata (Q.) Gaimard) oil. Eel fish oil was extracted using Soxhlet extraction with diethyl ether and purified through degumming, neutralization, and bleaching stages. Various adsorbents (bentonite, magnesol XL, and zeolite) were employed at different concentrations (1% bentonite, 3% magnesol XL, and 5% & 10% zeolite activated by acid and base) to remove impurities. The refined oils were analyzed for physical, chemical, and microbiological properties. Results showed that all adsorbents effectively improved the quality of eel fish oil, meeting most International Fish Oil Standard (IFOS) and Indonesian National Standard (SNI - 8467:2018) criteria. However, density and iodine values were below the specified limits. Microbiological analysis confirmed the absence of contamination, but lead levels exceeded the permissible standard.
The Effect of Seaweed Soy Tempe Extract on the Reduction of Blood Sugar Levels in Alloxan Induced Rats (Mus musculus) Abdul Hakim Laenggeng; Asriani Hasanuddin; Sitti Nuryanti; Manap Trianto
Jurnal Penelitian Pendidikan IPA Vol 11 No 7 (2025): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i7.11307

Abstract

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia due to impaired insulin secretion or action. This study aimed to examine the antihyperglycemic effect of seaweed soybean tempeh extract in alloxan-induced diabetic mice. A Completely Randomized Design (CRD) was used with 20 healthy male mice (2–3 months old, 25–30 g), divided into five groups: negative control, positive control (metformin), and three treatment groups receiving extract doses of 25, 75, and 125 mg/kg BW. Prior to treatment, mice underwent acclimatization to ensure uniform baseline conditions. Blood glucose levels were measured to assess the effects of the extract. Data were analyzed using ANOVA followed by the Least Significant Difference (LSD) test. The results showed that alloxan effectively induced hyperglycemia by damaging pancreatic beta cells. Administration of seaweed soybean tempeh extract significantly reduced blood glucose levels (p < 0.05). The highest dose (125 mg/kg BW) produced the most notable effect, comparable to metformin, while the 75 mg/kg BW dose also demonstrated significant efficacy. Both were significantly more effective than the lowest dose. In conclusion, seaweed soybean tempeh extract has potential as an alternative antihyperglycemic agent, especially at higher doses.