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All Journal Jurnal Bios Logos Jurnal Visi Ilmu Pendidikan AL KAUNIYAH ENVIAGRO Jurnal Pengabdian Kepada Masyarakat Universitas Bangka Belitung BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Jurnal SOLMA Paedagoria : Jurnal Kajian, Penelitian dan Pengembangan Kependidikan Biosaintifika: Journal of Biology & Biology Education Reformasi : Jurnal Ilmiah Ilmu Sosial dan Ilmu Politik Jurnal Pengabdian Masyarakat Borneo Journal of Integrated Agribusiness Jurnal Ilmiah Profesi Pendidikan EKOTONIA: Jurnal Penelitian Biologi, Botani, Zoologi dan Mikrobiologi Al-Mubin: Islamic Scientific Journal Journal of English Language and Education Berkala Penelitian Hayati ABDIPRAJA (Jurnal Pengabdian kepada Masyarakat) Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan JURNAL PARADIGMA: Journal of Sociology Research and Education Engagement: Jurnal Pengabdian Kepada Masyarakat Biosaintifika: Journal of Biology & Biology Education Musyawarah: Jurnal Pengabdian Masyarakat
Henny Helmi
Universitas Bangka Belitung
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Berkala Penelitian Hayati

 1 
ANTIBACTERIAL ACTIVITY OF BELILIK (Brucea javanica (L). MERR) AND BENTA (Wikstroemia androsaemofolia DECNE) TO INHIBIT THE GROWTH OF ENTEROPATHOGENIC BACTERIA Henny Helmi; Idha Susanti; Noptian Asmara Agung; Sadam Kusen
JURNAL PENELITIAN BIOLOGI BERKALA PENELITIAN HAYATI Vol 21 No 1 (2015): December 2015
Publisher : The East Java Biological Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.388 KB) | DOI: 10.23869/94

Abstract

Several native Indonesia plants have been used to prepare traditional medicine since long time ago. One of common diseases in tropical country is diarrhea, it caused by the infection of enteropathogenic bacteria such as Enteropathogenic Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Shigella sp. Belilik (Brucea javanica (L.) Merr) and Benta (Wikstroemia androsaemofolia Decne) are herbals that utilized as medicine for diarrhea in Bangka Belitung, Indonesia. Parts of these plants are mostly can be utilized as medicine, such as leaf, root, and fruit. The aims of this study were to investigate the antibacterial activity of ethanol crude extract of B. javanica (root and fruit) and W. androsaemofolia (leaf and fruit) against enteropathogenic bacteria (EPEC, P. aeruginoa, S. aureus, Shigella sp.). Meth od that used was papper disc diffusion. The results showed that at concentration 10 mg/mL, 20 mg/mL, and 30 mg/mL of B. javanica ethanol extract of both root and fruit could not inhibit the enteropathogenic bacteria, while the ethanol extract of leaf and fruit of W. androsaemofolia were shown inhibition activity on the growth of enteropathogenic bacte ria. W. androsaemofolia leaf extract performed the best inhibition activity to the growth of EPEC (20.55±1.5mm) and S. aureus (22.14±4.5mm), it was better than kanamycin performance at the same concentration (30 mg/mL). In addition, ethanol extract of W. androsaemofolia fruit showed the best inhibition activity against Shigella sp. (19.64±1.8mm).
PHYTOCHEMICAL TESTED AND IN VITRO SCREENING ANTI- MALARIA ACTIVITY OF BELILIK (Brucea javanica (L)). MERR AGAINST Plasmodium falciparum Henny Helmi; Idha Susanti
JURNAL PENELITIAN BIOLOGI BERKALA PENELITIAN HAYATI Vol 19 No 1 (2013): December 2013
Publisher : The East Java Biological Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.778 KB) | DOI: 10.23869/128

Abstract

Screening of anti-malaria compound from nature is one of important thing to cure malaria disease especially in Bangka Belitung province. One of plant that as used as traditional medicine to cure malaria is Belilik (Brucea javanica (L.)Merr. The aim of this study was to investigate the present of some kind of biochemical compound, and to evaluate in vitro anti-malaria activity of ethanol extracts of Bruce javanica fruits and roots against Plasmodium falciparum. A visual method was allowed to evaluate the in vitro anti-malaria activity of the extracts against P. falciparum. The number of parasites per 5,000 erythrocytes on thin Giemsa stained smears was calculated microscopically. IC50 values were determined by probit analysis of SPSS 13 program. The result showed, that the ethanol extract of Belilik contained some biochemical compound such as alkaloid, flavonoid and phenol in fruits and alkaloid, phenol and saponin in roots. The anti-malaria activity of ethanol extracts of Brucea javanica fruits and roots on P. falciparum were very effective as IC50<0,01 μg/mL. The highest inhibition of 100 μg/mL of Brucea javanica fruits and roots were 5.95% and 16.99% respectively. Brucea javanica could inhibit Plasmodium falciparum in vitro with very small dosage of extract and very potential to develop as malaria medicine.
Co-Authors Achmad Hufad Adikara, Fahmi Surya Ahmad Arsyadi Andriani, Dian Sri Anggraeni Anggraeni Apit Fathurohman Auliya Kurdiati, Lintang Azizah Husin Budi Afriyansyah Budi Afriyansyah Carroline, Intan Cucu Sukmana, Cucu Dari, Silvi Wulan Dea Indriani Astuti Elih Sudiapermana, Elih Eni Karsiningsih Eni Karsiningsih Eni, Kariningsih Erni Erni Esti Susiloningsih Febbi Julia Nandi Hadi Hadi Husain, Azizah Idha Susanti Jannah, Nurul ‘Ilmi Miftahul Julian Erika Putri Juliani, Intan Junita Junita Karina Karina Khusnul Khotimah Lingga, Rahmad Lista Nia Maryani Maryani MEGA NURRIZALIA, MEGA Meysari, Della Muhammad Soleh Rafsanjani Noptian Asmara Agung Oong Komar Pane, Aisyah Nurfadya Pingkan Aditiawati Puspa Ayu Pitayati Rahmad Lingga Rahmad Lingga Robby Gus Mahardika Robika Robika Roudhotul Jannah Rudi Dungani Sadam Kusen Salmi Salmi Salmi Salmi Sapitri, Erna Reta Saputra, Ardi Septiani, Yin Yin Septiani, Yiyin Septiyanda, Dwi Shinta Ahsaniyah SHOMEDRAN SHOMEDRAN, SHOMEDRAN Sri Andriani, Dian Tanzila, Siti Ade Ilma Vebriani, Helly Wiwied Ekasari Zaenab Fauziyah