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Serotipe Virus Dengue dan Populasi Aedes aegypti dan Aedes albopictus (Diptera: Culicidae) Di Kota Bengkulu Dessy Triana; Sitti Rahmah Umniyati; Budi Mulyaningsih; Munauwarus Sarirah
Berita Kedokteran Masyarakat (BKM) Vol 34, No 5 (2018)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (569.966 KB) | DOI: 10.22146/bkm.34730

Abstract

Dengue virus serotype and the population of Aedes aegypti and Aedes albopictus in Bengkulu City: its implications for dengue prevention programs Purpose: This study aimed to prevent the development of dengue virus by detecting dengue virus serotypes of Aedes aegypti (Ae. aegypti) and Aedes albopictus (Ae. albopictus) and to determine the population of Ae. aegypti and Ae. albopictus in dengue endemic area (Sidomulyo Village) and dengue sporadic area (Tanjung Jaya Village) in Bengkulu City, Indonesia. Methods: The design of study was observational-analytic. Aedes sp eggs were collected by ovitraps from Sidomulyo and Tanjung Jaya Villages. The eggs were reared to adult and identified to determine of Ae. aegypti and Ae. albopictus. Identification of species Ae. aegypti and Ae. albopictus uses the pictorial key for the identification of mosquitoes by Rueda. Detection of dengue virus serotypes were done by RT-PCR and nested PCR method using specific primers Lanciotti. Results: The Serotypes of dengue virus of Ae. aegypti in dengue endemic and sporadic areas were dengue-3 (DENV-3) and the serotypes of dengue virus of Ae. albopictus in dengue sporadic area was dengue-3 (DENV-3). The population ratio of Ae. aegypti and Ae. albopictus in dengue endemic area (61%:39%) and dengue sporadic areas (27%:73%), respectively. Conclusions: Aedes aegypti in dengue endemic and sporadic areas and Ae. albopictus in dengue sporadic area has potential as a dengue-3 vector. Health Agency of Bengkulu City could optimize the prevention program of dengue and activate the Jumantik cadres.AbstrakTujuan: Penelitian ini bertujuan untuk pencegahan perkembangan penyakit DBD dengan mendeteksi serotipe virus dengue pada nyamuk Ae. aegypti dan Ae. albopictus dan menentukan rasio populasi nyamuk Ae. aegypti dan Ae. albopictus di daerah endemis dan sporadis DBD di Kota Bengkulu. Metode: Desain penelitian ini adalah observasional-analitik. Telur nyamuk Aedes sp dikumpulkan menggunakan ovitrap dari daerah endemis DBD (Kelurahan Sidomulyo) dan daerah sporadis DBD (Kelurahan Tanjung Jaya). Identifikasi spesies Ae. aegypti dan Ae. albopictus menggunakan pictorial key for the identification of mosquitoes Rueda. Deteksi serotipe virus dengue dilakukan dengan metode RT-PCR dan Nested PCR menggunakan primer spesifik Lanciotti. Hasil: Serotipe virus dengue yang ditemukan pada Ae. aegypti adalah DENV-3 (daerah endemis dan sporadis DBD) dan DENV-3 pada Ae. albopictus (daerah sporadis DBD). Perbandingan populasi Ae. aegypti dan Ae. albopictus pada daerah endemis dan sporadis DBD berturut-turut adalah (60,51%:39,49%) dan (27,08%:72,92%). Simpulan: Aedes aegypti di daerah endemis dan sporadis DBD serta Ae. albopictus di daerah sporadis DBD berpotensi sebagai vektor dengue-3. Dinas Kesehatan Kota Bengkulu dapat mengoptimalkan program pencegahan DBD dan mengaktifkan kader Jumantik.
Spatial Distribution of COVID-19 Related to the Potential for Spreading Outbreaks and Vulnerability of a Region in Bengkulu Province on 2020 Naurah Shafa Putri Cahyangi; Dessy Triana; Liya Agustin Umar; Nikki Aldi Massardi; Utari Hartati Suryani; Riry Ambarsari
BENCOOLEN JOURNAL OF PHARMACY Vol. 2 No. 2 (2022): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v2i2.24359

Abstract

Coronavirus disease 2019 (COVID-19) was declared a pandemic on March 11, 2020, by the World Health Organization (WHO). The spread of COVID-19 increases with different conditions and situations in each region. Spatial distribution plays a role in identifying the vulnerability of an area. This study aimed to determine the differences in COVID-19 cases from one area to another in 10 regions in Bengkulu Province in 2020. This study is a descriptive study with an observational study through a cross-sectional approach using an epidemiological investigation form as a data source. Sampling was carried out from July to December 2020 and obtained from 3044 respondents who met the inclusion criteria. The total sampling technique did sampling. The relationship between the population density of an area and the severity of COVID-19 cases was statistically analyzed using the Spearman rank test. The results showed that areas with higher density levels, such as Bengkulu City, caused a wider spread of cases, causing the number of COVID-19 cases to increase compared to other areas with lower population densities in Bengkulu Province. There is no significant relationship between population density and the severity of COVID-19
The Correlation Between Adult Age Factors toward The Clinical Manifestation and The Severity Level of COVID-19 in Bengkulu Province in 2020 Begumratu VOCA; Dia Triyani Putri; Dessy Triana; Riry Ambarsari; Nikki Aldi Massardi; Utari Hartati Suryani
BENCOOLEN JOURNAL OF PHARMACY Vol. 2 No. 2 (2022): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v2i2.24362

Abstract

Coronavirus Disease-19 (COVID-19) is an acute respiratory disease in Wuhan, China, and was discovered discovered in 2019. The things that need to be considered in COVID-19 patients include their clinical manifestation and the severity level of COVID-19. The severity level of COVID-19 patients is associated with age. Each age has a different proportion of severity. The study aimed to determine the correlations among adult age with clinical manifestation and severity of COVID-19 in Bengkulu Province 2020. This study used an observational analytic study. The sample was 108 patients 19 - ≥65 years old and confirmed positive for COVID-19 in 2020. The assessment used the epidemiological investigation form and medical record from Dr. M.Yunus Hospital. At the same time, the severity level of COVID-19 was obtained from the measurement based on the COVID-19 Prevention and Control Guidelines by the Indonesian Ministry of Health. The results showed that the subjects in 19 – 23 years old mostly have asymptomatic severity, 24 – 64 years old mostly have mild severity, and ≥65 years old have moderate severity. It was concluded that there was a significant correlation between the severity of COVID-19 in Bengkulu Province in 2020.
The correlation between Children’s Age Factors toward the clinical manifestation and the severity level of COVID-19 in Bengkulu Province in 2020 Dia Triyani Putri; Begumratu VOCA; Diah Ayu Aguspa Dita; Dessy Triana; Riry Ambarsari; Utari Hartati Suryani
BENCOOLEN JOURNAL OF PHARMACY Vol. 2 No. 2 (2022): Oktober
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v2i2.24363

Abstract

Coronavirus Disease 2019 (COVID-19) is a disease that can infect people of all ages. Symptoms can range from asymptomatic to severe in certain age groups. It can occur due to differences in the innate immune response, comorbidities and the function, distribution, maturation of the SARS-CoV-2 receptor. This study aimed to determine the correlation between children’s age factors toward the clinical manifestation and the severity level of COVID-19 in Bengkulu Province in 2020. An observational analytic study with cross-sectional design was used in this study. This study included 86 children aged 0-18 years old who were confirmed positive for COVID-19 and lived in Bengkulu Province from March to December 2020. The clinical manifestation was assessed using the COVID-19 epidemiological investigation form and medical records from M.Yunus Hospital. The degree of severity is determined using Ministry of Health of Indonesia’s Guidelines for COVID-19 Prevention and Control. The result showed that of the majority of children aged 0-1 years old, 5-11 years old, and 12-18 years old have asymptomatic severity illness. While children are between the ages of two and four, the majority of their illnesses are of a mild severity. There was no significant correlation between children age factors and the severity of COVID-19 in Bengkulu Province in 2020.