Article Per Year (5 Year)
p-Index From 2021 - 2026
1.687
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Cosmogov: Jurnal Ilmu Pemerintahan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmasipha Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Klinik dan Sains Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Journal of Pharmascience
Eka Kumalasari
Akademi Farmasi ISFI Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

Published : 16 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 16 Documents
Search

 1   2 
IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B DALAM KERUPUK BERWARNA MERAH YANG BEREDAR DI PASAR ANTASARI KOTA BANJARMASIN Eka Kumalasari
Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v1i1.17

Abstract

Crackers are made from tapioca flour batter mixed with flavorings and colorings, still many outstanding crackers that contain ingredients banned dye Rhodamine B. Rhodamine B is a chemical used for red dye in the textile industry and plastic. Rhodamine B can cause cancer, poisoning, lung irritation, sore eyes, and sore throat. This study aims to identify and determination the levels of Rhodamine B in circulating red crackers Antasari market Banjarmasin.The population is that sold in the red crackers that sold in Antasari market Banjarmasin.. The sampling is technique incidental sampling , that is based on chance, so any population by chance met with researchers can be used as a sample. Identification of Rhodamine B was done by Thin Layer Chromatography (TLC) by using the stationary phase silica GF 254 and mobile phase is elution solvent is n-butanol, ethyl acetate, ammonia (10:4:5). Then detected with a UV lamp 254 nm and 366 nm. While for the determination of levels using Vis spectrophotometry at a wavelength of 544 nm.The results showed that the samples of 6 found one sample containing Rhodamine B, namely samples 5 (cassava crackers matches) and obtained values of 7,25 ± 3,8640 levels mg / kg. Based on these results, Rhodamine B still found in crackers that sold in the market Antasari Banjarmasin.
Pengaruh pemberian benalu teh dan benalu mangga terhadap kadar malondialdehid serum pada tikus wistar jantan Ma'ruf, Muhammad; Sjakoer, Nour Athiroh Abdoes; Mubarakati, Nurul Jadid; Kumalasari, Eka
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 9 No. 1 (2025): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v9i1.12534

Abstract

Tea mistletoe and mango mistletoe are plants known to possess strong antioxidant activity. The antioxidants in these plants play a role in combating free radicals, inhibiting cell oxidation, and reducing the risk of cellular damage. The active compounds present in tea and mango mistletoe have the potential to reduce malondialdehyde (MDA) levels caused by free radical exposure. This study aimed to evaluate the effect of tea and mango mistletoe (BTBM) administration on MDA levels in male Wistar rats induced with deoxycorticosterone acetate (DOCA)-salt. This study used 25 male Wistar rats, divided into five groups: normal, control (DOCA-salt), and three treatment groups receiving BTBM at doses of 50, 100, and 200 mg/kgBW. The study lasted 28 days, beginning with BTBM administration for 14 days, followed by DOCA-salt induction alongside BTBM administration from day 15 to day 28. MDA levels were measured using the Thiobarbituric Acid Reactive Substances (TBARS) method with a UV-Vis spectrophotometer at a wavelength of 531 nm. Data were statistically analyzed using one-way ANOVA, followed by a Post Hoc Tukey test to determine differences between groups. The results showed that BTBM administration at a dose of 50 mg/kgBW significantly (p<0.05) reduced MDA levels compared to the control group. Thus, it can be concluded that the combination of tea and mango mistletoe has potential as an antioxidant agent in reducing MDA levels, with 50 mg/kgBW as the optimal dose in the DOCA-salt-induced rat model.      
KARAKTERISTIK PARAMETER SPESIFIK DAN NON SPESIFIK DAUN KRATOM (Mitragyna speciosa Korh.) ASAL KALIMANTAN SELATAN Febrianti, Dwi Rizki; Wahyuono, Subagus; Fakhrudin, Nanang; Riski, Akhmad; Kumalasari, Eka; Normilawati; Niah, Rakhmadhan; Mar'uf, Muhammad
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2786

Abstract

Standardization is a process of fulfilling the requirements for raw materials of traditional medicine, aimed at ensuring and maintaining safety, consistent quality, and efficacy. Kratom leaves (Mitragyna speciosa) are a traditional medicinal plant found in the interior regions of Kalimantan. This plant functions as a source of energy due to its stimulant properties. This study aims to determine the standardization of kratom leaf extract simplicia, including both specific and non-specific parameters. The extraction method used in this study was maceration with ethanol. The results showed that the scientific name of kratom leaves is Mitragyna speciosa. The standardization of kratom leaf simplicia powder includes parameters such as loss on drying, total ash, water-insoluble ash, acid-insoluble ash, total microbial count (ALT), total yeast and mold count (AKK), and heavy metal contamination, with the following results: 9.5%; 5.51%; 3.58%; 0.39%; 6.9 × 10² cfu/g; >3.0 × 10³ cfu/g; <0.001 mg/kg. Meanwhile, the standardization of kratom leaf extract includes ash content and heavy metal contamination, with results of 6.06% and <0.001 mg/kg, respectively. The active compounds contained in the kratom leaf simplicia and extract are alkaloids, flavonoids, and tannins.
STANDARDISASI KULIT PISANG KEPOK (Musa paradisiaca L) SEBAGAI ALTERNATIF PENYEMBUH LUKA Ariani, Novia; Kumalasari, Eka; Fawwazi, Muhammad Hafizh Abiyyu Fathin; Nayandra, Faizah; Purnomo, Dimas Kalinggo; Rahayu, Mirenne Anik Sri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2814

Abstract

Kepok banana peel (Musa paradisiaca) is an agricultural waste with great potential to be utilized as a raw material for traditional medicine. Several studies have demonstrated that kepok banana peel contains bioactive compounds that act as antioxidants, antibacterial agents, and accelerate the wound healing process. Standardization of the simplicia and extract is necessary to ensure quality, safety, and consistency of its effectiveness as a phytopharmaceutical. This study aims to standardize kepok banana peel through both specific and non-specific parameters. The extraction method employed in this research was sonication using ethanol as a solvent. The results showed that kepok banana peel contains active compounds such as alkaloids, flavonoids, and saponins. Standardization tests on the simplicia powder of kepok banana peel included determination of water content, total ash, acid-insoluble ash, ethanol-soluble extract, water-soluble extract, total plate count (TPC), yeast and mold count (YMC), and heavy metal contamination, with the following results: 10.34%; 9%; 2.25%; 0.06%; 6.91%; 10.26%; >3.0 × 10³ cfu/g; 5.7 × 10³; <0.001 mg/kg, respectively. Meanwhile, the standardization results for the kepok banana peel extract were as follows: 9.57%; 11.19%; 0.07%; 0.26%; 21.68%; 22.53%; 4.6 × 10³ cfu/g; 8.2 × 10³; <0.001 mg/kg.
Identifikasi Mutu Simplisia dan Ekstrak Serta Uji Aktivitas Antioksidan Ekstrak Daun Sungkai (Peronema canescens Jack) Ma'ruf, Muhammad; Febrianti, Dwi Rizki; Kumalasari, Eka; Amukti, Danang Prasetyaning; Santoso, Blegoh Iwan
Jurnal Farmasi Klinik dan Sains Vol 5, No 2 (2025): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v5i2.1862

Abstract

Sungkai (Peronema canescens Jack.) merupakan salah satu tanaman yang telah lama dimanfaatkan oleh masyarakat sebagai obat tradisional untuk berbagai jenis penyakit. Tanaman ini khususnya pada bagian daun diketahui mengandung flavonoid alkaloid saponin tanin dan terpenoid atau steroid yang berperan sebagai antioksidan. Namun data terkait variasi mutu simplisia dan ekstrak daun sungkai masih terbatas sehingga berpotensi memengaruhi konsistensi aktivitas dan kualitas produk herbal. Penelitian ini bertujuan untuk mengetahui kandungan kimia dalam simplisia dan ekstrak daun sungkai, serta menguji kemampuan antioksidannya dengan metode DPPH. Penelitian ini diawali dengan pengambilan daun sungkai segar yang kemudian diolah menjadi simplisia dan diekstraksi menggunakan etanol 96% melalui metode maserasi. Karakterisasi simplisia dan ekstrak dilakukan melalui uji organoleptik, penetapan parameter spesifik dan nonspesifik, serta skrining fitokimia. Uji aktivitas antioksidan dilakukan dengan metode DPPH menggunakan vitamin C sebagai pembanding serta mengacu pada kriteria klasifikasi nilai IC₅₀ untuk menentukan tingkat kekuatan aktivitas antioksidan. Hasil penelitian ini menunjukkan bahwa simplisia dan ekstrak daun sungkai mengandung alkaloid, flavonoid, saponin, tanin, serta terpenoid/steroid. Parameter mutu simplisia memenuhi standar Farmakope Herbal Indonesia. Uji DPPH menghasilkan nilai IC₅₀ vitamin C sebesar 7,80 ppm dan ekstrak daun sungkai sebesar 14,55 ppm. Keduanya termasuk kategori aktivitas antioksidan sangat kuat, meskipun ekstrak daun sungkai sedikit lebih rendah dibanding vitamin C. Temuan ini menunjukkan bahwa daun sungkai berpotensi dikembangkan sebagai sumber antioksidan alami serta menjadi dasar dalam upaya standardisasi bahan baku dan pengembangan sediaan herbal.
Analisis Kualitatif Kandungan Ibuprofen Dalam Jamu Pegal Linu Yang Beredar di Pasar Baru Permai Banjarmasin Eka Kumalasari; Linda Fitria Wahyuni; Riza Alfian
Journal of Pharmascience Vol. 5 No. 1 (2018): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v5i1.5783

Abstract

ABSTRAK Ibuprofen merupakan obat yang berkhasiat untuk menghilangkan nyeri, menurunkan demam, peradangan seperti rematik dan encok. Efek samping yang paling bahaya jika digunakan dalam jangka panjang atau dalam dosis tinggi dapat menyebabkan kerusakan permukaan saluran gastrointestinal dan pendarahan. Tujuan dilakukan penelitian ini untuk mengetahui ada atau tidaknya kandungan Ibuprofen pada jamu pegal linu yang beredar di pasar Baru Permai Banjarmasin. Jenis penelitian ini adalah penelitian bersifat deskriptif. Metode penelitian yang digunakan yaitu metode analisis kualitatif dengan kromatografi lapis tipis. Penelitian dilaksanakan di Laboratorium Kimia Akademi Farmasi ISFI Banjarmasin dari tanggal 15 – 19 Juni 2017. Teknik sampling yang digunakan yaitu sampling jenuh. Sampel di ambil dari toko obat di Pasar Baru Permai Banjarmasin, didapatkan 15 sampel jamu pegal linu dengan merek berbeda. Analisis KLT menggunakan eluen dari campuran etil asetat, metanol, dan ammonia dengan perbandingan 85:10:5 dan plat KLT silica gel GF254 dengan Rf Ibuprofen yaitu 0,87. Dari hasil penelitian didapatkan 14 dari 15 sampel atau 93,3% dari total sampel mengandung Ibuprofen. Kata Kunci : Ibuprofen, Jamu Pegal Linu, KLT ABSTRACT Ibuprofen is a medicine to relieve pain, fever, inflammation such as rheumatism and gout. The most dangerous side effects when used in the long term or in high doses can cause damage to the gastrointestinal tract and bleeding. The purpose of this research is to know the presence or absence of Ibuprofen content in jamu pegal linu which is circulating in market Baru Permai Banjarmasin. The type of research is descriptive. The method used is qualitative analysis with thin layer chromatography. The research was conducted at ISFI Banjarmasin Pharmacy Laboratory from 15-19 June 2017. The sampling technique used was saturated sampling. Samples are taken from pharmacies in the in pasar Baru Permai Banjarmasin. The researcher obtained 15 herbal samples with various brands. TLC analysis used eluent from mixture of ethyl acetate, methanol, and ammonia with ratio 85: 10: 5 and KLT silica gel plate GF254 with Rf Ibuprofen was 0.87. From the results obtained 14 of 15 samples or 93.3% of the total sample positively contained Ibuprofen Keywords: Ibuprofen, Pegal Linu Herbal Medicine, TLC
Co-Authors Achmad Mursyidi Aisyah, Noor Aisyah, Noor Aisyah Amelia, Senya Puteri Ariani, Novia Aryzki, Saftia Danang Prasetyaning Amukti Erlina Erlina Febrianti, Dwi Rizki Hamidah, Marina Illahi, Fitrah Shafran Khadijah, Maulida Laela Hayu Nurani Linda Fitria Wahyuni Ma'ruf, Muhammad Marta Fransiska, Revita Muhammad Hafizh Abiyyu Fathin Fawwazi Muhammad Ma'ruf Nafisa Berliana, Siti Nanang Fakhrudin, Nanang Nanik Sulistyani Nayandra, Faizah Niah, Rakhmadhan Norhilaliyah, Norhilaliyah Normilawati Nour Athiroh Abdoes Sjakoer Nurman Nurul Jadid Mubarokati Prihandiwati, Erna Purnomo, Dimas Kalinggo Rahayu, Mirenne Anik Sri Riski, Akhmad Riza Alfian Rohman, Abdul Sandi, Dita Ayulia Dwi Santoso, Blegoh Iwan Siska Musiam Subagus Wahyuono Supomo Supomo Wahyuni, Amaliyah Widyarini, Sitarina Yuli, Annisa Rahma Yumassik, Abdul Mahmud Zainab Zainab