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All Journal Pharmaciana: Jurnal Kefarmasian Cosmogov: Jurnal Ilmu Pemerintahan Pharmascience Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmasipha Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Eka Kumalasari
Akademi Farmasi ISFI Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER CLAY KOMBINASI EKTRAK ETANOL DAUN BAWANG DAYAK DAN KULIT JERUK SIAM Musiam, Siska; Ma'ruf, Muhammad; Kumalasari, Eka
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i3.2298

Abstract

Clay masks are a popular cosmetic due to their ability to rejuvenate the skin and detoxify the face. Clay masks can be made by adding dayak onion leaves and Siamese banjar orange peel, known to be rich in natural antioxidants containing various complex secondary metabolites. The aim of this research is to formulate and evaluate a clay mask preparation made from a combination of ethanol extracts of dayak onion leaves and Siamese banjar orange peel. The samples were extracted using the maceration method with 70% ethanol as a solvent. The ethanol extracts were then formulated into clay masks using kaolin as the base material, with ratios of 1:1, 2:1, and 1:2. The organoleptic evaluation showed no changes in color, odor, or texture of the masks during storage. All formulations were homogeneous with an average pH ranging from 5.19 to 5.97. The viscosity test results ranged from 29.14 to 37.05 Pa’s, the average spreadability was 27.12-38.90 mm, and the drying time ranged from 15.21 to 17.58 minutes. It can be concluded that the ethanol extract combination of dayak onion leaves and Siamese banjar orange peel can be formulated into a stable clay mask and all formulations meet the required physical evaluation.
THE IMPACT OF PVA CONCENTRATION ON THE PHYSICAL QUALITY OF THE Eleutherine palmifolia (L.) Merr LEAVES PEEL-OFF GEL MASK Kumalasari, Eka; Prihandiwati, Erna; Ma'ruf, Muhammad; Ariani, Novia; Amelia, Senya Puteri; Fawwazi, Muhammad Hafizh Abiyyu Fathin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2277

Abstract

The natives of Central Kalimantan utilize Eleutherine palmifolia (l.) Merr as a traditional medicine to treat various diseases. Eleutherine palmifolia  leaves are rich in flavonoid substances. Eleutherine palmifolia  leaves extract has an IC50 value of 45.33 ppm, indicating significant antioxidant activity. Antioxidants are helpful in reducing the risk of UV radiation-induced skin damage. Eleutherine palmifolia leaves have antioxidant properties that can be used as a peel-off gel mask. Polyvinyl alcohol (PVA) bases come in various formulations for peel-off gel mask that F1 10%, F2 12%, and F3 14%. The concentration of PVA is the most significant element affecting how well peel-off gel masks create films. This study aims to determine the impact of PVA concentration on the physical of the Eleutherine palmifolia  leaves Peel-off gel mask. All formulas are tested for organoleptics, homogeneity, spreadability, pH value, and drying speed. The results showed that all peel-off gel mask compositions pass the physical properties test. A one-way ANOVA statistical analysis reveals a significant variation in the preparations drying speeds (p<0,05).
IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B DALAM KERUPUK BERWARNA MERAH YANG BEREDAR DI PASAR ANTASARI KOTA BANJARMASIN Eka Kumalasari
Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v1i1.17

Abstract

Crackers are made from tapioca flour batter mixed with flavorings and colorings, still many outstanding crackers that contain ingredients banned dye Rhodamine B. Rhodamine B is a chemical used for red dye in the textile industry and plastic. Rhodamine B can cause cancer, poisoning, lung irritation, sore eyes, and sore throat. This study aims to identify and determination the levels of Rhodamine B in circulating red crackers Antasari market Banjarmasin.The population is that sold in the red crackers that sold in Antasari market Banjarmasin.. The sampling is technique incidental sampling , that is based on chance, so any population by chance met with researchers can be used as a sample. Identification of Rhodamine B was done by Thin Layer Chromatography (TLC) by using the stationary phase silica GF 254 and mobile phase is elution solvent is n-butanol, ethyl acetate, ammonia (10:4:5). Then detected with a UV lamp 254 nm and 366 nm. While for the determination of levels using Vis spectrophotometry at a wavelength of 544 nm.The results showed that the samples of 6 found one sample containing Rhodamine B, namely samples 5 (cassava crackers matches) and obtained values of 7,25 ± 3,8640 levels mg / kg. Based on these results, Rhodamine B still found in crackers that sold in the market Antasari Banjarmasin.
Pengaruh pemberian benalu teh dan benalu mangga terhadap kadar malondialdehid serum pada tikus wistar jantan Ma'ruf, Muhammad; Sjakoer, Nour Athiroh Abdoes; Mubarakati, Nurul Jadid; Kumalasari, Eka
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 9 No. 1 (2025): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v9i1.12534

Abstract

Tea mistletoe and mango mistletoe are plants known to possess strong antioxidant activity. The antioxidants in these plants play a role in combating free radicals, inhibiting cell oxidation, and reducing the risk of cellular damage. The active compounds present in tea and mango mistletoe have the potential to reduce malondialdehyde (MDA) levels caused by free radical exposure. This study aimed to evaluate the effect of tea and mango mistletoe (BTBM) administration on MDA levels in male Wistar rats induced with deoxycorticosterone acetate (DOCA)-salt. This study used 25 male Wistar rats, divided into five groups: normal, control (DOCA-salt), and three treatment groups receiving BTBM at doses of 50, 100, and 200 mg/kgBW. The study lasted 28 days, beginning with BTBM administration for 14 days, followed by DOCA-salt induction alongside BTBM administration from day 15 to day 28. MDA levels were measured using the Thiobarbituric Acid Reactive Substances (TBARS) method with a UV-Vis spectrophotometer at a wavelength of 531 nm. Data were statistically analyzed using one-way ANOVA, followed by a Post Hoc Tukey test to determine differences between groups. The results showed that BTBM administration at a dose of 50 mg/kgBW significantly (p<0.05) reduced MDA levels compared to the control group. Thus, it can be concluded that the combination of tea and mango mistletoe has potential as an antioxidant agent in reducing MDA levels, with 50 mg/kgBW as the optimal dose in the DOCA-salt-induced rat model.      
KARAKTERISTIK PARAMETER SPESIFIK DAN NON SPESIFIK DAUN KRATOM (Mitragyna speciosa Korh.) ASAL KALIMANTAN SELATAN Febrianti, Dwi Rizki; Wahyuono, Subagus; Fakhrudin, Nanang; Riski, Akhmad; Kumalasari, Eka; Normilawati; Niah, Rakhmadhan; Mar'uf, Muhammad
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2786

Abstract

Standardization is a process of fulfilling the requirements for raw materials of traditional medicine, aimed at ensuring and maintaining safety, consistent quality, and efficacy. Kratom leaves (Mitragyna speciosa) are a traditional medicinal plant found in the interior regions of Kalimantan. This plant functions as a source of energy due to its stimulant properties. This study aims to determine the standardization of kratom leaf extract simplicia, including both specific and non-specific parameters. The extraction method used in this study was maceration with ethanol. The results showed that the scientific name of kratom leaves is Mitragyna speciosa. The standardization of kratom leaf simplicia powder includes parameters such as loss on drying, total ash, water-insoluble ash, acid-insoluble ash, total microbial count (ALT), total yeast and mold count (AKK), and heavy metal contamination, with the following results: 9.5%; 5.51%; 3.58%; 0.39%; 6.9 × 10² cfu/g; >3.0 × 10³ cfu/g; <0.001 mg/kg. Meanwhile, the standardization of kratom leaf extract includes ash content and heavy metal contamination, with results of 6.06% and <0.001 mg/kg, respectively. The active compounds contained in the kratom leaf simplicia and extract are alkaloids, flavonoids, and tannins.
STANDARDISASI KULIT PISANG KEPOK (Musa paradisiaca L) SEBAGAI ALTERNATIF PENYEMBUH LUKA Ariani, Novia; Kumalasari, Eka; Fawwazi, Muhammad Hafizh Abiyyu Fathin; Nayandra, Faizah; Purnomo, Dimas Kalinggo; Rahayu, Mirenne Anik Sri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2814

Abstract

Kepok banana peel (Musa paradisiaca) is an agricultural waste with great potential to be utilized as a raw material for traditional medicine. Several studies have demonstrated that kepok banana peel contains bioactive compounds that act as antioxidants, antibacterial agents, and accelerate the wound healing process. Standardization of the simplicia and extract is necessary to ensure quality, safety, and consistency of its effectiveness as a phytopharmaceutical. This study aims to standardize kepok banana peel through both specific and non-specific parameters. The extraction method employed in this research was sonication using ethanol as a solvent. The results showed that kepok banana peel contains active compounds such as alkaloids, flavonoids, and saponins. Standardization tests on the simplicia powder of kepok banana peel included determination of water content, total ash, acid-insoluble ash, ethanol-soluble extract, water-soluble extract, total plate count (TPC), yeast and mold count (YMC), and heavy metal contamination, with the following results: 10.34%; 9%; 2.25%; 0.06%; 6.91%; 10.26%; >3.0 × 10³ cfu/g; 5.7 × 10³; <0.001 mg/kg, respectively. Meanwhile, the standardization results for the kepok banana peel extract were as follows: 9.57%; 11.19%; 0.07%; 0.26%; 21.68%; 22.53%; 4.6 × 10³ cfu/g; 8.2 × 10³; <0.001 mg/kg.
Co-Authors Achmad Mursyidi Aisyah, Noor Aisyah, Noor Aisyah Amelia, Senya Puteri Ariani, Novia Aryzki, Saftia Erlina Erlina Febrianti, Dwi Rizki Hamidah, Marina Illahi, Fitrah Shafran Khadijah, Maulida Laela Hayu Nurani Ma'ruf, Muhammad Mar'uf, Muhammad Marta Fransiska, Revita Muhammad Hafizh Abiyyu Fathin Fawwazi Muhammad Ma'ruf Nafisa Berliana, Siti Nanang Fakhrudin, Nanang Nanik Sulistyani Nayandra, Faizah Niah, Rakhmadhan Norhilaliyah, Norhilaliyah Normilawati Nour Athiroh Abdoes Sjakoer Nurman Nurul Jadid Mubarokati Prihandiwati, Erna Purnomo, Dimas Kalinggo Rahayu, Mirenne Anik Sri Riski, Akhmad Rohman, Abdul Sandi, Dita Ayulia Dwi Siska Musiam Subagus Wahyuono Supomo Supomo Wahyuni, Amaliyah Widyarini, Sitarina Yuli, Annisa Rahma Yumassik, Abdul Mahmud Zainab Zainab