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All Journal Journal of Food and Pharmaceutical Science Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Biota Pharmascience ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemical Analysis (IJCA) Science Midwifery Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pijar MIPA Jurnal Bakti Untuk Negeri Jurnal Nusantara Berbakti Journal of Food and Pharmaceutical Sciences Borneo Journal of Pharmacy Prosiding Seminar Nasional Pengabdian Masyarakat
Amalia Khairunnisa
Departement Of Pharmacy, Faculty Of Mathematics And Natural Sciences, Universitas Lambung Mangkurat
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The Kualitas Kacang Tanah (Arachis hypogeae L.) Kefir dengan Variasi Konsentrasi Starter Ragi dan Lama Fermentasi Pratika Viogenta; Nani Kartinah; Amalia Khairunnisa; Fathur Rahman
Biota Vol 7 No 2 (2021): Jurnal Biota 2021
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/Biota.v7i2.8147

Abstract

One of the fermented milk products, namely kefir, is increasingly popular because it has many health benefits. Peanut juice has a high enough protein content that it can be used as a substitute for animal milk. The purpose of this study was to determine the quality of peanut kefir with variations in the concentration of ragi tape inoculum and fermentation time. This research method used 3 variations in the concentration of tape yeast (1, 2 and 4%) and long fermentation time (24, 48 and 72 hours). The results showed that the highest total LAB was in 4% ragi tape inoculum with a fermentation time of 24 hours (4.4x108 cells/mL) and the lowest was in 4% tape yeast inoculum with a fermentation time of 72 hours (9.8x107 cells/mL) and total yeast between 1x104 cells/mL - 3x105 cells/mL) and alcohol produced <1%. Total acid obtained between 6% - 17.6%. The increase in total acid is proportional to the decrease in pH. The pH of the peanut kefir medium was between 3.44 - 4.12. Peanut kefir with tape yeast inoculum meets the standard requirements for fermented milk and can replace milk kefir.
Aktivitas Antibakteri Ekstrak Metanol Bunga Teratai (Nymphaea pubescens Willd) Amalia Khairunnisa; Nashrul Wathan; Mia Fitriana; Fadlilaturrahmah Fadlilaturrahmah; Nisriyati Fiddina
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8486

Abstract

Nymphaea pubescens Willd telah diketahui mempunyai efek antibakteri, terutama pada biji dan daunnya. Tetapi sampai saat ini bagian bunga dari tanaman tersebut belum dilakukan pengujian aktivitas antibakteri. Tujuan dari penelitian ini untuk melakukan skrining fitokimia, uji aktivitas antibakteri dan penentuan konsentrasi hambat minimum (KHM) dari ekstrak metanol bunga N. pubescens terhadap S. aureus dan E. coli. Proses ekstraksi bunga N. pubescens dimaserasi menggunakan pelarut metanol dengan perbandingan 1: 4 b/v. Metode pengujian yang digunakan ada dua yaitu metode difusi untuk pengujian aktivitas antibakteri dan metode dilusi untuk pengukuran konsentrasi hambat minimum (KHM). Hasil skrining fitokimia didapatkan bahwa ekstrak metanol bunga N. pubescens mengandung senyawa golongan fenolik, saponin dan flavonoid. Hasil pengujian aktivitas antibakteri menunjukkan bahwa ekstrak metanol bunga N.pubescens mampu menghambat S. aureus (diameter hambat 10 ± 0,29 mm) dan E.coli (diameter hambat 10,2 ± 0,50 mm). Konsentrasi hambat minimum dari ekstrak metanol bunga N. pubescens terhadap S.aureus sebesar 12,5% dan terhadap E.coli sebesar 25%. Dapat disimpulkan bahwa ekstrak metanol bunga N. pubescens memiliki aktivitas sebagai antibakteri. Nymphaea pubescens Willd has known to have antibacterial effects, especially on the seeds and leaves. However, until now the flower of the plant has not been tested for antibacterial activity. The purpose of this study was to perform phytochemical screening, antibacterial activity test and determine the minimum inhibitory concentration (MIC) of the methanol extract of N. pubescens flowers against S. aureus and E. coli. The process of extracting N. pubescens flowers is macerated using methanol as a solvent with a ratio of 1: 4 w / v. There are two test methods used, namely the diffusion method for testing antibacterial activity and the dilution method for measuring the minimum inhibitory concentration (MIC). The results of phytochemical screening showed that the methanol extract of N. pubescens flowers contained phenolic compounds, saponins, and flavonoids. The results of the antibacterial activity test showed that the methanol extract of N.pubescens flowers was able to inhibit S. aureus (inhibition diameter 10 ± 0.29 mm) and E. coli (inhibitory diameter 10.2 ± 0.50 mm). The minimum inhibitory concentration of the methanol extract of N. pubescens flowers against S.aureus was 12.5% and against E. coli was 25%. It can be concluded that the methanol extract of N. pubescens flowers has antibacterial activityKeywords: Nymphaea pubescens, lotus flower, methanol extract, antibacterial
Penambatan Molekul Kandungan Eurycoma longifolia Jack. (Pasak bumi) terhadap Human Phosphodiesterase 5 Samsul Hadi; Khoerul Anwar; Amalia Khairunnisa; Noer Komari
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8731

Abstract

Pasak bumi sebagai obat tradisional pria telah digunakan oleh masyarakat melayu, khususnya orang Sumatra dan kalimantan, akan tetapi mekanisme secara molekuler belum dikatahui dengan jelas. Salah satu pendekatan yang dapat digunakan untuk mengetahui mekanisme pasak bumi sebagai obat tradisional yang bermanfaat mengatasi disfungsi ereksi adalah penambatan molekul. Penambatan melekul dilakukan dengan cara melihat interaksi ligand dengan reseptor. Ligand yang berasal dari pasak bumi adalah 5-methoxycanthin-6-one, 9-methoxycanthin-6-one, eurycomalactone, eurycomalide A, eurycomanone, eurycomaoside, laurycolactone A, longilactone, niloticin, picrasidine O. Sehingga kesepuluh ligand ini didocking menggunakan salah satu aplikasi docking yaitu PLANTS 1.1 untuk melihat ikatan dengan PDE5. Sebelum dilakukan docking terhadap ligand pasak bumi, terlebih dahulu dilakukan docking terhadap ligand Sildenafil untuk melhat nilai RMSD. RMSD ini diperlukan sebagai alat validasi metode, berdasarkan percobaan, nilai RMSD dari Sildenafil adalah 1,2517 A0. Hasil terbaik dari penambatan molekul pasak bumi adalah niloticin dengan skor doking -97,8802, sehingga nilai interaksinya terhadap reseptor sebesar 93,71% dari Sildenafil.Pasak bumi as traditional male medicine has been used by Malay people, especially Sumatra and Borneo people, but the molecular mechanism is not yet known clearly. One approach that can be used to determine the mechanism of the Pasak Bumi as a traditional medicine that is useful to overcome erectile dysfunction is docking molecules. Molecular docking is done by looking at the interaction of ligands with receptors. Ligands originating from the Pasak Bumi are 5-methoxycanthin-6-one, 9-methoxycanthin-6-one, eurycomalactone, eurycomalide A, eurycomanone, eurycomaoside, laurycolactone A, longilactone, niloticin, picrasidine O. docking application namely PLANTS 1.1 to see the bond with PDE5. Before docking Pasak Bumi ligand, it is first docking Sildenafil ligand to see the RMSD value. The RMSD is needed as a method validation method, based on experiments, the RMSD value of Sildenafil is 1.2517 A0. The best results from docking of the Pasak bumi molecule is niloticin with a doctor score of -97.8802, so interaction skor to the receptor is 93.71% of Sildenafil.Keywords: Pasak Bumi, PDE5, PLANTS
UJI AKTIVITAS TABIR SURYA DAN ANTIOKSIDAN EKSTRAK ETANOL DAUN SUNGKAI (Perenema canescens Jack) Fadlilaturrahmah Fadlilaturrahmah; Amalia Khairunnisa; Aditya MP Putra; Ivanna Sinta
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (436.265 KB) | DOI: 10.36387/jiis.v6i2.737

Abstract

Indonesia, which is located in the tropics, causes people's skin to easily experience premature aging and tan. Most of these cosmetic products contain dangerous synthetic chemicals. For this reason, cosmetic products with natural active ingredients or phytocosmetics that are effective and safe to use need to be developed. One of the typical natural plant plants from South Kalimantan that has the potential to be developed as a cosmetic preparation is Sungkai (Peronema canescens Jack). The aim of the study was to determine the antioxidant activity and sunscreen activity of Sungkai leaves. The method used for the determination of antioxidant activity is the DPPH method using a uv-vis spectrophotometer and for the determination of sunscreen activity using a uv-vis spectrophotometer. The results showed that the P. canescens plant extract contained anthraquinones, flavonoids, saponins, tannins, and phenols. P.canescens plants have an Inhibitory Concentration 50 (IC50 ) of 42.219±19.440 ppm and have sunscreen activity with spf (Sun Protecting Factor) values ??with concentrations of 600 ppm, 400 ppm, 200 respectively as follows: 24±0.31; 16±0.34; and 8±0.3. The conclusion of this study Sungkai (Peronema canescens Jack) has antioxidant activity and has sunscreen activity so that it has the potential to be developed into natural skin care.
PENETAPAN KADAR FLAVONOID TOTAL DAN NILAI SUN PROTECTION FACTOR (SPF) DARI EKSTRAK KERING DAUN CEMPEDAK (Artocarpus integer) Muhammad Ikhwan Rizki; Syifa Auliani; Amalia Khairunnisa; Fadlilaturrahmah Fadlilaturrahmah; Normaidah Normaidah; Anna Khumaira Sari
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.868

Abstract

Ultraviolet rays cause wrinkles and premature ageing. The bad effects of sun exposure can be avoided by using sunscreen. Artocarpus integer is empirically used as a black spot remover and cold powder. Total flavonoid content is an extract quality parameter that is related to the consistency of the pharmacological effects produced. The purpose of this study was to determine the total flavonoid content and the value of Sun Protection Factor (SPF) from the dried extract Artocarpus integer. The study began with a drying of fresh leaves using an oven, making simplicia powder, extraction process by maceration, and drying extracts using a drying cabinet. The dry extract was measured for total flavonoid content using a spectrophotometer UV-Vis with quercetin as a marker. The dry extract also determined the SPF value at concentrations of 200, 400, 600, 800, and 1000 ppm. The results showed that the total flavonoid content of the dry extract of cempedak leaves was 1,283 ± 0.032 %w/w equivalent to quercetin. The SPF value of dry extract of cempedak leaves at concentrations of 200, 400, 600, 800, and 1000 ppm respectively, namely 2,923 ± 0.009, 5.990 ± 0.002, 8.846 ± 0.001, 13,181 ± 0.008 and 15.856 ± 0.1533
PENGOLAHAN LIMBAH CAIR TAHU MENJADI Nata de Soya DI KABUPATEN BANJAR, KALIMANATAN SELATAN Pratika Viogenta; Amalia Khairunnisa; Samsul Hadi
Jurnal Bakti untuk Negeri Vol 2 No 1 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.902 KB)

Abstract

One of the home industries located in Martapura, Banjar Regency, is a tofu factory. The raw material for making tofu is soybean seeds which are processed so that the main product is tofu. In addition to producing tofu, the factory also produces by-products in the form of liquid waste and solid waste. So far, liquid waste is not used, but solid waste is used as animal feed. For this reason, in the application of science and technology, skills are given in the form of training to utilize liquid waste from the tofu industry into a new product, namely Nata de Soya. Nata de Soya is a highly nutritious food product, especially in the content of carbohydrates, protein and crude fiber. The methods used in this training are lectures and demonstrations. The purpose of this program is to add insight and skills to tofu industry players and the community, especially around the factory in processing liquid waste into Nata de Soya products. The results of this study increased public knowledge about the consequences of improper waste disposal and processing as well as increased knowledge of fermentation technology products and even succeeded in utilizing the tofu industrial liquid waste into processed fermented food in the form of Nata de Soya.
PENGEMBANGAN PRODUK DAN DIGITALISASI PEMASARAN PADA USAHA KECIL OBAT TRADISIONAL (UKOT) PJ PUCUK SIRIH ASAL BANJARMASIN Anna Khumaira Sari; Muhammad Ikhwan Rizki; Fadlillaturahmah Fadlillaturahmah; Amalia Khairunnisa khairunnisa; Muhammad Rusydi Taufik; Devi Eka Pratama; Akhsanul Rahmatullah Rahmatullah
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (550.34 KB)

Abstract

South Kalimantan is a wetland area that has a high level of biodiversity, both plants and animals, which can be used as raw materials for herbal products. The herbal medicine company Pucuk Sirih is a Traditional Medicine Small Business which is located in selling various herbal products. PJ Pucuk Sirih wants to develop and innovate products, packaging and marketing systems because since the first production there has been no change in product, packaging and marketing system development. The new product formula, namely Harbumin Capsules (haruan fish capsules) has not yet produced good product quality, this is indicated by the wet capsule products after the production process so it is necessary to evaluate the product formula. The purpose of this community service is to provide training on production and packaging methods in accordance with CPOTB, evaluate the Harbumin capsule formula, produce a digitalized marketing system with website development. The result of the activity is that the production team gains knowledge regarding good production and packaging methods, the results of the evaluation of Harbumin capsule products show that the capsules have met the requirements, the marketing and sales system has been digitized and can be obtained online
Authentication of Combretum Indicum Varr. B Flower Against Varr. M with Combined Chemometrics of UV-VIS Spectrophotometric: indonesia Samsul Hadi; Elvina Astria Agustin; Amalia Khairunnisa; Irawati Irawati; Linda Wahyuni
Science Midwifery Vol 10 No 3 (2022): August: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i2.577

Abstract

Melati belanda flowers have two varieties that look different, namely from the shape of the flowers. The first variety has the shape of an elongated flower and the second variety has the shape of a rounded flower. So that, this difference in the shape of the flower will allow generating different activities. The purpose of this study was to identify the distinctive spectra of these two varieties. The method used is a fingerprint analysis of UV-VIS spectroscopy combined with chemometrics for the identification and authentication of varieties of Melati belanda. The results of the analysis of PLSR Combretum indicum Varr. B against Combretum indicum Varr. M on a spectrum of 218.86-252.54 nm, The first derivatization of RMSEC 2.39; R2 0.9975; RMSEP 6.92; R2 0.9939 and RMSEC 5.63; R2 0.9868. Meanwhile, with a wavelength of 253,260 – 299,020, a normal model of RMSEC 2.01 was obtained; R2 0.9983; RMSEP 1.89; R2 0.9985 and RMSEC 1; R2 0.9772. So can be concluded below UV-VIS spectroscopic fingerprint analysis combined with chemometrics is able to identify the authentication of the Combretum Indicum Varr. B against the occurrence of adulteration of flowers Combretum Indicum Varr. M at a wavelength of 253.260 – 299.020 nm of normal models.
PENETAPAN KADAR FLAVONOID TOTAL DAN NILAI SUN PROTECTION FACTOR (SPF) DARI EKSTRAK KERING DAUN CEMPEDAK (Artocarpus integer) Muhammad Ikhwan Rizki; Syifa Auliani; Amalia Khairunnisa; Fadlilaturrahmah Fadlilaturrahmah; Normaidah Normaidah; Anna Khumaira Sari
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.868

Abstract

Ultraviolet rays cause wrinkles and premature ageing. The bad effects of sun exposure can be avoided by using sunscreen. Artocarpus integer is empirically used as a black spot remover and cold powder. Total flavonoid content is an extract quality parameter that is related to the consistency of the pharmacological effects produced. The purpose of this study was to determine the total flavonoid content and the value of Sun Protection Factor (SPF) from the dried extract Artocarpus integer. The study began with a drying of fresh leaves using an oven, making simplicia powder, extraction process by maceration, and drying extracts using a drying cabinet. The dry extract was measured for total flavonoid content using a spectrophotometer UV-Vis with quercetin as a marker. The dry extract also determined the SPF value at concentrations of 200, 400, 600, 800, and 1000 ppm. The results showed that the total flavonoid content of the dry extract of cempedak leaves was 1,283 ± 0.032 %w/w equivalent to quercetin. The SPF value of dry extract of cempedak leaves at concentrations of 200, 400, 600, 800, and 1000 ppm respectively, namely 2,923 ± 0.009, 5.990 ± 0.002, 8.846 ± 0.001, 13,181 ± 0.008 and 15.856 ± 0.1533
Analisis Antioksidan Ekstrak Etanol Daun Ceguk (Combretum indicum L.) varr.M dengan Berbagai Lokasi Kalimantan Selatan, Indonesia Samsul Hadi; Umi Nur Hapifah; Amalia Khairunnisa
Journal of Food and Pharmaceutical Sciences Vol 10, No 3 (2022): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.5427

Abstract

Indicum has 2 variations, especially in terms of flowers, namely elongated and rounded types with antioxidant effects. So the aim of this research is to know the antioxidant of C. Indicum leaves, one of the varieties in Banjar, Banjarbaru and Tanah Laut areas, that variety is C. indicum varr.M. Antioxidant testing using TLC and quantitative using UV-Vis spectrophotometer. The antioxidant results qualitatively have antioxidant activity marked by a yellowish white stain. The quantitative test results of Banjar, Banjarbaru and Tanah Laut have 97.2219±0.263 ppm, 50.0832±0.078 ppm and 56.2046±0.185 ppm IC50 values. The results of One Way Anova analysis on the ethanol extract of elongated C. indicum leaves from Banjar, Banjarbaru and Tanah Laut had significant differences between each location and other locations. Based on these results Banjarbaru has the best antioxidants.
Co-Authors Aditya MP Putra Akhsanul Rahmatullah Anna Khumaira Sari Arif Subekti Arnida Arnida Chatarina Umbul Wahyuni Desy Aulia Azzahra Devi Eka Pratama Dian Ekowati Dyera Forestryana Elvina Astria Agustin Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fadlillaturahmah Fadlillaturahmah Faisal Faisal Fathur Rahman Fathur Rahman Hafiz Ramadhan Irawati Irawati Ivanna Sinta Khoerul Anwar Liana Fitriani Hasymi Linda Wahyuni Maulidia Maulidia Mia Fitriana Muhammad Ikhwan Rizki Muhammad Rusydi Taufik Mulia Mulia Nani Kartinah Nashrul Wathan Nisriyati Fiddina Noer Komari Normaidah, Normaidah Salma Salma Samsul Hadi Suci Kamelia Sutomo Sutomo Syifa Auliani Umi Nur Hapifah Viogenta, Pratika Wiwin Tyas Istikowati