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All Journal Journal of Food and Pharmaceutical Science Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Biota Pharmascience ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemical Analysis (IJCA) Science Midwifery Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pijar MIPA Jurnal Bakti Untuk Negeri Jurnal Nusantara Berbakti Journal of Food and Pharmaceutical Sciences Borneo Journal of Pharmacy Prosiding Seminar Nasional Pengabdian Masyarakat
Amalia Khairunnisa
Departement Of Pharmacy, Faculty Of Mathematics And Natural Sciences, Universitas Lambung Mangkurat
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PENGEMBANGAN PRODUK DAN DIGITALISASI PEMASARAN PADA USAHA KECIL OBAT TRADISIONAL (UKOT) PJ PUCUK SIRIH ASAL BANJARMASIN Anna Khumaira Sari; Muhammad Ikhwan Rizki; Fadlillaturahmah Fadlillaturahmah; Amalia Khairunnisa khairunnisa; Muhammad Rusydi Taufik; Devi Eka Pratama; Akhsanul Rahmatullah Rahmatullah
Jurnal Bakti untuk Negeri Vol 2 No 2 (2022): JBN
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jbn.v2i2.1133

Abstract

South Kalimantan is a wetland area that has a high level of biodiversity, both plants and animals, which can be used as raw materials for herbal products. The herbal medicine company Pucuk Sirih is a Traditional Medicine Small Business which is located in selling various herbal products. PJ Pucuk Sirih wants to develop and innovate products, packaging and marketing systems because since the first production there has been no change in product, packaging and marketing system development. The new product formula, namely Harbumin Capsules (haruan fish capsules) has not yet produced good product quality, this is indicated by the wet capsule products after the production process so it is necessary to evaluate the product formula. The purpose of this community service is to provide training on production and packaging methods in accordance with CPOTB, evaluate the Harbumin capsule formula, produce a digitalized marketing system with website development. The result of the activity is that the production team gains knowledge regarding good production and packaging methods, the results of the evaluation of Harbumin capsule products show that the capsules have met the requirements, the marketing and sales system has been digitized and can be obtained online
Autentikasi Batang Combertum Indicum varr. B terhadap Batang varr. M dengan Metode Spektrofotometri UV VIS-kemometrik. Samsul Hadi; Amalia khairunnisa; Salma Salma; Suci Kamelia
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 4, No 1 (2023): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v4i1.10697

Abstract

Batang Melati belanda (Combretum indicum) mempunyai kandungan kimia seperti tanin, dimana tanaman ini memiliki dua varietas yang memungkinkan menghasilkan aktivitas yang berbeda yaitu varietas batang membulat dan varietas batang memanjang. Penelitian ini bertujuan mengidentifikasi spektra khas dari kedua varietas batang Melati belanda dengan pendekatan autentikasi dan adulterasi. Analisis dilakukan dengan metode sidik jari spektroskopi UV-VIS yang dikombinasikan dengan kemometrika PLSR serta analisis diskriminan. Hasil model prediksi terbaik ditunjukkan pada model normal rentang panjang gelombang 249.32-221.72 nm dengan nilai akurasi 100%, R2 kalibrasi 0.9987, R2 prediksi 0.998, RMSEC 1.71, dan REMSEP 0.786. Berdasarkan hasil tersebut kombinasi spektroskopi UV-VIS dan kemometrik dapat digunakan untuk identifikasi, diskriminasi, dan autentikasi dari varietas batang Combertum Indicum Varr. B terhadap batang Combertum Indicum Varr. M yaitu pada model normal panjang gelombang 249.32-221.72 nm
Determination of flavonoid levels of Macaranga gigantea and its activity as antioxidants Samsul Hadi; Dian Ekowati; Amalia Khairunnisa
Jurnal Pijar Mipa Vol. 18 No. 1 (2023): January 2023
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v18i1.4054

Abstract

One of the ways to prevent generative diseases is by using natural antioxidant compounds. The flavonoid compounds in the flower parts of M. gigantea have a role in antioxidants. Thus the study aimed to test the antioxidant activity and flavonoid levels of M. gigantea flowers. The antioxidant test was carried out by UV-vis spectrophotometry using 2,2-diphenyl-1-picrylhydrazyl and flavonoid assay using 10% aluminum chloride and potassium acetate, both tests using quercetin as a comparison. The results of this test obtained IC50 antioxidants 145,725 ± 3.858 ppm, and flavonoids were 1,860 ± 0.007% w/w eq quercetin. The conclusion from the experiments that have been carried out is that M. gigantea flowers have moderate antioxidant abilities.
Skrining senyawa Combretum Indicum sebagai inhibitor Caspase 3 secara In Silico Samsul Hadi; Salma Salma; Amalia khairunnisa; Suci Kamelia
Jurnal Farmasi Sains dan Terapan Vol 9, No 2 (2022): October
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v9i2.3999

Abstract

Osteoarthritis ialah gangguan sendi degeneratif yang ditandai dengan erosi cartilage artikular. Salah satu protein yang mempunyai peran besar dalam penyakit ini adalah caspase sub type 3. Sehingga tujuan dari penelitian ini adalah skrining senyawa belanda yang berpotensi sebagai inhibitor caspase 3. Metode dari penelitian ini menggunakan seanyawa yang terkandung dalam Combretum indicum, data ini kemudian dilakukan docking menggunakan software PLANTS. Hasil dari penelitian ini adalah scor docking dari masing masing senyawa yaitu Isatin Sulfonamide -90,8975; Casuariin -92,4942; asquisqualic acid -90,8911; 1-desgalloyleugeniin -100,988; arachidonic acid -63,4613; Punicalin -88,2142; linoleic acid - 97,4111; gallic acid -59,1281; Rutin-95,3717; ellagic acid -63,6793; methyl ursolate -77,5611; flavogallonic acid -80,8221; Quisqualic acid -63,1281; brevifolin carboxylic acid -71,5203; Trigonelline-59,8987; Quercetin -74,4091; quinoline-4-carbonitrile -61,5971; β-sitosterol -87,3881; Pedunculagin-86,843 Lupeol -76,4221; Punicalagin -82,1754; linalool -67,8673; Eugeniin -100,7541.Oleh karena itu senyawa yang berpotensi sebagai inhibitor caspase 3 adalah Rutin, linoleic acid, asquisqualic acid, Eugenin, Casuariin, 1-desgalloyleugeniin.
Antioxidant Test and Flavonoids Determination of Tuber Pakis Kinca (Nephrolepis cordifolia (L) C. Presl) Samsul Hadi; Arif Subekti; Amalia Khairunnisa
Indonesian Journal of Chemical Analysis (IJCA) Vol. 6 No. 1 (2023): Indonesian Journal of Chemical Analysis
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijca.vol6.iss1.art1

Abstract

One of the things that causes cell damage in the body is the formation of unpaired electrons, also known as free radicals, which can cause oxidative stress. Excessive oxidative stress is not maintained by the body's natural antioxidants, so natural antioxidants are needed from outside. One of the plants suspected of having antioxidant abilities is Pakis kinca. So, the aim of this study was to determine the levels of flavonoids and antioxidant abilities in the tuber of N. cordifoli. Therefore, the method used to determine flavonoids is by reacting with AlCl3 and reading by UV-vis spectrophotometry, while reacting antioxidants with DPPH using spectrophotometry. The results of the flavonoid test were 3.119 ± 0.09 w/w equivalent to quercetin, from this equation the flavonoid content in the range of the equation was obtained. The results of the antioxidant test obtained the mean value of antioxidants was 93.898 ± 0.923. The conclusion obtained is that the antioxidant IC50 value of tuber extract N. cordifolia is a strong category with a total flavonoid content of 3.119 ± 0.091 w/w equivalent to quercetin.
Analisis Antioksidan Ekstrak Etanol Daun Ceguk (Combretum indicum L.) varr.M dengan Berbagai Lokasi Kalimantan Selatan, Indonesia Samsul Hadi; Umi Nur Hapifah; Amalia Khairunnisa
Journal of Food and Pharmaceutical Sciences Vol 10, No 3 (2022): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.5427

Abstract

Indicum has 2 variations, especially in terms of flowers, namely elongated and rounded types with antioxidant effects. So the aim of this research is to know the antioxidant of C. Indicum leaves, one of the varieties in Banjar, Banjarbaru and Tanah Laut areas, that variety is C. indicum varr.M. Antioxidant testing using TLC and quantitative using UV-Vis spectrophotometer. The antioxidant results qualitatively have antioxidant activity marked by a yellowish white stain. The quantitative test results of Banjar, Banjarbaru and Tanah Laut have 97.2219±0.263 ppm, 50.0832±0.078 ppm and 56.2046±0.185 ppm IC50 values. The results of One Way Anova analysis on the ethanol extract of elongated C. indicum leaves from Banjar, Banjarbaru and Tanah Laut had significant differences between each location and other locations. Based on these results Banjarbaru has the best antioxidants.
Peel-off Kefir Mask Arachi (Arachis hypogaea L.): Characterization and Antioxidant Activity Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Fathur Rahman; Mulia Mulia
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2597

Abstract

This study aims to determine the best formulation for the peel-off mask Arachi or peanut (Arachis hypogaea L). Arachis hypogaea kefir as an active ingredient is added with variations in the concentration of F1 (0.5%) and F2 (2%) (w/v). Organoleptic tests, homogeneity, dry time, and pH were carried out on the peel-off mask that had been made. Antioxidant test (DPPH methods) was performed on masks F1 and F2. The results showed that the peel-off mask of A. hypogaea kefir had the best antioxidant activity at a concentration of 2% (F2) kefir with an IC50 value of 1.865 ppm and was very active. The characteristics of the peel-off mask have good physical stability, proven by not experiencing a change in color, odor, being homogeneous, having good dispersion power, and having a dry time ranging from 10-23 minutes. The pH value of the peel-off mask preparation is 4.52, and it is appropriate with SNI and the pH balance of normal human skin. The peel-off mask of A. hypogaea kefir can be produced because has good physical stability and antioxidant activity.
Standardization of Simplicia and Ethanol Extract of Purun Danau (Lepironia articulata (Retz.) Domin) Rhizome Arnida Arnida; Maulidia Maulidia; Amalia Khairunnisa; Sutomo Sutomo; Faisal Faisal
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2794

Abstract

Purun Danau (Lepironia articulata (Retz.) Domin) has been shown to have antimalarial and antioxidant activity. This study aimed to standardize simplicia and extract of L. articulata by determining the value of its specific and non-specific parameters. A sampling of L. articulata rhizome was carried out in Guntung Manggis, Haur Gading, and Halat. The standardization method used was based on the Indonesian Herbal Pharmacopoeia and the General Standard Parameter of Extract. The organoleptic observations showed that L. articulata simplicia was reddish-brown in color, chelated taste, and had a specific odor. Microscopic observation showed parts of this plant: epidermis, cortex, endodermis, parenchyma, bundle vessels, and scalariform vessels. Ethanol-soluble extract content was 10.00-12.66%, water-soluble extract content 8.03-10.87%, drying shrinkage 7.10-7.33%, total ash content 2.03-2.52%, acid-insoluble ash 0.33-0.42%, Pb content 5.698-9.989 ppm, Cd content 0.300-0.500 ppm, Hg content 0.070-0.090 ppm. Ethanol extract of L. articulata rhizome contained alkaloids, flavonoids, tannins, glycosides, and saponins. The yield obtained was 8.05-11.23%, total ash content was 1.58-1.67%, acid-insoluble ash was 0.23-0.33%, and water content was 7.10-8.50%. Standardization of simplicia and ethanol extract of L. articulata rhizome has met the criteria.
Edukasi Penerapan Teknologi Fermentasi melalui Pembuatan Kefir dan Yogurt Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Arnida Arnida; Sutomo Sutomo; Fadlilaturrahmah Fadlilaturrahmah
Jurnal Nusantara Berbakti Vol. 2 No. 4 (2024): Oktober : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v2i3.411

Abstract

Fermentation technology can increase added value to agricultural, food and other products. Through fermentation, raw materials can be converted into products with higher selling value, such as cheese, yogurt, tempeh, wine, beer, and so on. Many fermented products are beneficial for health, for example kefir and yogurt which contain good probiotics. for digestion. Kefir is a type of fermented milk whose manufacture uses various microorganisms to produce lactic acid products with by-products such as ethanol, free fatty acids and acetaldehyde. Kefir is made by adding yeast which contains many microorganisms from the lactic acid bacteria and yeast groups, while yogurt is fermented milk with lactic acid bacteria (LAB).  This service activity aims to increase people' knowledge and skills regarding the application of fermentation technology, starting from the meaning of fermentation, fermentation methods to high-value products produced from the fermentation process. In this activity, socialization activities were carried out regarding the development of fermentation technology, especially kefir and cow's milk yogurt, as well as practices on how to make it among the residents of Balitra Jaya Permai Loktabat Utara. The results show an increase in residents' knowledge and skills regarding fermentation through pretest and posttest activities as well as practical activities.
The Characterization of Capsule Shell from Acid-Hydrolyzed Palm Oil Starch Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Desy Aulia Azzahra
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.93550.72-81

Abstract

Acid hydrolysis of palm trunk starch can increase the amylose content in starch, providing a stronger and more stable film. This study aims to obtain the best-modified starch concentration ratio with hydroxypropyl methylcellulose (HPMC) and identify their characteristics. Modifying palm trunk starch was conducted with an acetic buffer using CH3COONa and CH3COOH, decolorizing starch with activated carbon. Manufacturing a capsule shell was performed with weight ratio variations of modified starch and HPMC 1:1 (F1), 2:1 (F2), and 3:1 (F3). All formulations produced firm and elastic capsule shells. The capsule products were consistent in an average weight of F1 (0.10 g), F2 (0.11 g), and F3 (0.14 g). The average disintegration test results were F1 (10 minutes, 27.57 seconds), F2 (6 minutes, 47.06 seconds), and F3 (4 minutes, 34.24 seconds). Tensile strength results were F1 (2.147 MPa), F2 (2.565 MPa), and F3 (2.159 MPa). Fourier Transform Infrared (FTIR) results showed a vibration at a wavenumber of 1560 cm-1 corresponding to the characteristic fingerprint of the C–O vibration stretching in the capsule shell made from starch modified by HPMC. The concentration of modified starch affects the capsule shell’s characteristics, showing that capsule shell F2 (2:1) has the best formulation.
Co-Authors Aditya MP Putra Akhsanul Rahmatullah Anna Khumaira Sari Arif Subekti Arnida Arnida Chatarina Umbul Wahyuni Desy Aulia Azzahra Devi Eka Pratama Dian Ekowati Dyera Forestryana Elvina Astria Agustin Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fadlillaturahmah Fadlillaturahmah Faisal Faisal Fathur Rahman Fathur Rahman Hafiz Ramadhan Irawati Irawati Ivanna Sinta Khoerul Anwar Liana Fitriani Hasymi Linda Wahyuni Maulidia Maulidia Mia Fitriana Muhammad Ikhwan Rizki Muhammad Rusydi Taufik Mulia Mulia Nani Kartinah Nashrul Wathan Nisriyati Fiddina Noer Komari Normaidah, Normaidah Salma Salma Samsul Hadi Suci Kamelia Sutomo Sutomo Syifa Auliani Umi Nur Hapifah Viogenta, Pratika Wiwin Tyas Istikowati