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Studi Profil Metabolit Pada Organ Tikus Hasil Uji Toksisitas Sub Kronis Ekstrak Etanol 70% Daun Justicia Gendarussa Nur Irhamni Sabrina; Luthfiatu Kanina; Bambang Prajogo EW; Retno Widyowati; Suciati Suciati
Jurnal Serambi Engineering Vol 8, No 1 (2023): Januari 2023
Publisher : Fakultas Teknik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jse.v8i1.5580

Abstract

AbstractJusticia gendarussa Burm.f has been traditionally used as male contraceptionin in Indonesia. Gandarusa leaves contain gendarusin A which has potential as an antifertility agent. To prove that gandarusa leaves are safe to use as a male contraceptive, a subchronic toxicity test was carried out on this plant. Acute and subchronic oral toxicity studies of Justicia gendarussa Burm.f in rats were performed in the previous study in order to evaluate its safety. The aim of this study is to identify the metabolite profile of rat organ results of their subchronic toxicity test. Seven organs of rat such as kidney, hepar, testis, limph, instestine, lung, and heart were extracted using methanol and their profile metabolites were identified using UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS by positive and negatif mode. The results showed that all sampels contain 22 compounds from the positive ionization mode and 35 compounds from the negatif ionization mode. Compounds identified from the positive mode were dominated by amino acid groups, then compounds identified from the negatif mode were dominated by fatty acids and their derivatives. There were 35 metabolites that identified from the organ samples of the rat resulting subchronic toxicity test using the UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS method.Keywords: Justicia gendarussa Burm.f, rats, organ, metabolite profile
Enhancing the Knowledge and Skill of PKK and Karang Taruna Cadres in The Innovation of Mangosteen Fruit Products Suciati Suciati; Wiwied Ekasari; Andang Miatmoko; Neny Purwitasari; Lidya Tumewu; Yanu Andhiarto; Fatin Fadhilah Hasib; Tri Widiandani; Kholis Amalia Nofianti
Jurnal Pengabdian Masyarakat Vol 4 No 2 (2023): Jurnal Pengabdian Masyarakat
Publisher : Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpm.v4i2.1897

Abstract

Purpose: The current community service activities aim to provide knowledge and skills related to mangosteen and its processed products to the Songgon Village community Method: Transfer of knowledge and skill by lecturing and practice. Pre and post-tests were carried out to evaluate the participants’ knowledge before and after the workshop. Practical Applications: The knowledge and skill gained by PKK and Karang Taruna cadres in this workshop can be implemented in daily life. The participants learned how to make innovative products from mangosteen fruit so that it can be produced commercially. Thus, in the long term is expected to increase the income of Songgon Village Community. Conclusion: The results showed the participants' enthusiasm to participate in this activity, and the pre and post-tests demonstrated increased knowledge and skills. The next step requires intensive support for the Songgon Village community so that their products can be distributed commercially and provide economic benefits.
Upaya Peningkatan Kualitas Produk UMKM Makanan Minuman di Surabaya Melalui Pelatihan Keamanan Aditif dan Kemasan Pangan serta Program Self Declare Halal Menggunakan Aplikasi SEHATI: Efforts to Improve the Quality of Food and Beverage MSME Products in Surabaya Through Additive and Food Packaging Safety Training as well as a Self-declare Halal Program Using the SEHATI Application Kholis Amalia Nofianti; Juni Ekowati; Bambang Tri Purwanto; Adistiar Prayoga; Mochammad Yuwono; Adistiar Prayoga; Muhammad Agus Syamsur Rijal; Suciati Suciati; Diajeng Putri Paramita; Melanny Ika Sulistyowaty; Luqmanul Hakim
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 8 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i8.7044

Abstract

MSMEs in the food sector are the dominant economic support in Indonesia. Surabaya has more than 60 thousand MSMEs. In food production at the MSME level, food additives and packaging is inevitable. Despite the current regulations, people still encounter dangerous food additives or packaging. This is caused by a lack of knowledge and awareness of food producers and consumers. On the other hand, since the implementation of the halal guarantee system, the use of halal labels on food and beverage products has become very important. For MSMEs, the government makes it easy to get a halal label through the self-declare halal program using the SEHATI. This activity aims to provide training on safe food additives and packaging, halal food, and the self-declare halal program using the SEHATI application in Surabaya. Carrying out activities using presentation and two-way interaction. Evaluate activities through pretest and posttest for each topic. The lowest values for food packaging, it is 52.92 and 79.58. The highest value was shown by the halal topic with an average of 69.58 and 97.92. The significance of the increase in value was demonstrated by the Wilcoxon test using SPSS 22 which showed the Asymp. Sig (2-tailed) value for the three topics less than 0.05. Thus, it can be concluded that this activity has proven to be able to improve participants' abilities regarding safe food additives and packaging, as well as halal food and the introduction of the self-declare halal program.