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Studi Profil Metabolit Pada Organ Tikus Hasil Uji Toksisitas Sub Kronis Ekstrak Etanol 70% Daun Justicia Gendarussa Nur Irhamni Sabrina; Luthfiatu Kanina; Bambang Prajogo EW; Retno Widyowati; Suciati Suciati
Jurnal Serambi Engineering Vol 8, No 1 (2023): Januari 2023
Publisher : Fakultas Teknik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jse.v8i1.5580

Abstract

AbstractJusticia gendarussa Burm.f has been traditionally used as male contraceptionin in Indonesia. Gandarusa leaves contain gendarusin A which has potential as an antifertility agent. To prove that gandarusa leaves are safe to use as a male contraceptive, a subchronic toxicity test was carried out on this plant. Acute and subchronic oral toxicity studies of Justicia gendarussa Burm.f in rats were performed in the previous study in order to evaluate its safety. The aim of this study is to identify the metabolite profile of rat organ results of their subchronic toxicity test. Seven organs of rat such as kidney, hepar, testis, limph, instestine, lung, and heart were extracted using methanol and their profile metabolites were identified using UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS by positive and negatif mode. The results showed that all sampels contain 22 compounds from the positive ionization mode and 35 compounds from the negatif ionization mode. Compounds identified from the positive mode were dominated by amino acid groups, then compounds identified from the negatif mode were dominated by fatty acids and their derivatives. There were 35 metabolites that identified from the organ samples of the rat resulting subchronic toxicity test using the UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS method.Keywords: Justicia gendarussa Burm.f, rats, organ, metabolite profile
Enhancing the Knowledge and Skill of PKK and Karang Taruna Cadres in The Innovation of Mangosteen Fruit Products Suciati Suciati; Wiwied Ekasari; Andang Miatmoko; Neny Purwitasari; Lidya Tumewu; Yanu Andhiarto; Fatin Fadhilah Hasib; Tri Widiandani; Kholis Amalia Nofianti
Jurnal Pengabdian Masyarakat Vol 4 No 2 (2023): Jurnal Pengabdian Masyarakat
Publisher : Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpm.v4i2.1897

Abstract

Purpose: The current community service activities aim to provide knowledge and skills related to mangosteen and its processed products to the Songgon Village community Method: Transfer of knowledge and skill by lecturing and practice. Pre and post-tests were carried out to evaluate the participants’ knowledge before and after the workshop. Practical Applications: The knowledge and skill gained by PKK and Karang Taruna cadres in this workshop can be implemented in daily life. The participants learned how to make innovative products from mangosteen fruit so that it can be produced commercially. Thus, in the long term is expected to increase the income of Songgon Village Community. Conclusion: The results showed the participants' enthusiasm to participate in this activity, and the pre and post-tests demonstrated increased knowledge and skills. The next step requires intensive support for the Songgon Village community so that their products can be distributed commercially and provide economic benefits.
Pelatihan inovasi produk berbahan kulit buah manggis sebagai upaya peningkatan perekonomian masyarakat Desa Songgon Kabupaten Banyuwangi Suciati Suciati; Wiwied Ekasari; Andang Miatmoko; Neny Purwitasari; Fatin Fadhilah Hasib; Hilkatul Ilmi; Firman Wicaksana; Hamizah Haula
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 2 (2025): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i2.28952

Abstract

Abstrak Desa Songgon adalah salah satu desa di Kabupaten Banyuwangi yang dikembangkan sebagai desa wisata. Desa ini memiliki kekayaan alam yang melimpah terutama buah manggis sebagai komoditas unggulan. Masyarakat Desa Songgon memanfaatkan buah manggis untuk konsumsi sehari-hari dan dijual. Harga buah manggis di pasaran sangat fluktuatif terutama saat musimnya harganya sangat murah.  Permasalahan lain yang dihadapi adalah dari kulit buah manggis yang kerap kali hanya menjadi limbah rumah tangga. Oleh karena itu perlu adanya program peningkatan pengetahuan dan keterampilan terkait pengolahan kulit buah manggis menjadi berbagai produk berdaya jual serta strategi pemasarannya kepada warga Desa Songgon. Metode yang dilakukan berupa penyuluhan dan praktek pembuatan produk kepada kader PKK dan karang taruna Desa Songgon. Hasil dari kegiatan ini adalah meningkatnya pengetahuan peserta dilihat dari kenaikan nilai pre-test 54,9 menjadi 83,9 pada post-test. Peserta juga mendapatkan keterampilan dalam pembuatan teh celup dan sabun antibakteri dengan bahan dasar kulit buah manggis.  Hasil uji aktivitas antioksidan dari teh celup mangostana dan mangostana mix yang dibuat menunjukkan bahwa produk teh yang dibuat memiliki aktivitas antioksidan yang baik. Pengetahuan dan keterampilan yang diperoleh kader PKK dan Karang Taruna diharapkan dapat diimplementasikan dalam kehidupan sehari-hari. Peserta belajar bagaimana membuat produk inovatif dari buah manggis sehingga dapat diproduksi secara komersial. Dengan demikian, dalam jangka panjang diharapkan dapat meningkatkan pendapatan masyarakat Desa Songgon. Kata kunci: Desa Songgon; Banyuwangi; buah manggis; inovasi produk. Abstract Songgon Village is one of the villages in Banyuwangi Regency that is developed as a tourist village. This village is rich in natural resources, with mangosteen being one of the most valuable commodities. The people of Songgon Village use mangosteen for daily consumption and for trade. The price of mangosteen on the market is very fluctuating, especially during mangosteen season, it is very cheap. Another issue faced is the mangosteen rind often becomes household waste. The purpose of this community service is to enhance the knowledge and skills of the residents of Songgon Village regarding the processing of mangosteen rind into a variety of innovative health products as well as the marketing strategy of the product. The method used is counseling and practices for PKK cadres and youth organizations of Songgon Village. The results of this program showed that there was an increase in the knowledge of participants according to the pre-test score (54,9) to 83,9 in post-test. Participants also gain the skill in making tea and soap from mangosteen rinds. The antioxidant activity of the tea products, mangostana and mangostana mix, showed good antioxidant activity of the tea infusion. The knowledge and skill gain by participants related innovative products from mangosteen fruit can be implemented, so that they can be produced commercially. Thus, in the long term it is expected to increase the income of the Songgon Village residents. Keywords: Songgon Village; Banyuwangi; mangosteen; innovative products.