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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA ALCHEMY Jurnal Penelitian Kimia Jurnal Serambi Engineering Jurnal Pengabdian Masyarakat Asia Humanism : Jurnal Pengabdian Masyarakat
Suciati Suciati
Departemen Farmakognosi Dan Fitokimia, Fakultas Farmasi, Universitas Airlangga, Surabaya
Religion Arts Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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Studi Profil Metabolit Pada Organ Tikus Hasil Uji Toksisitas Sub Kronis Ekstrak Etanol 70% Daun Justicia Gendarussa Nur Irhamni Sabrina; Luthfiatu Kanina; Bambang Prajogo EW; Retno Widyowati; Suciati Suciati
Jurnal Serambi Engineering Vol 8, No 1 (2023): Januari 2023
Publisher : Fakultas Teknik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jse.v8i1.5580

Abstract

AbstractJusticia gendarussa Burm.f has been traditionally used as male contraceptionin in Indonesia. Gandarusa leaves contain gendarusin A which has potential as an antifertility agent. To prove that gandarusa leaves are safe to use as a male contraceptive, a subchronic toxicity test was carried out on this plant. Acute and subchronic oral toxicity studies of Justicia gendarussa Burm.f in rats were performed in the previous study in order to evaluate its safety. The aim of this study is to identify the metabolite profile of rat organ results of their subchronic toxicity test. Seven organs of rat such as kidney, hepar, testis, limph, instestine, lung, and heart were extracted using methanol and their profile metabolites were identified using UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS by positive and negatif mode. The results showed that all sampels contain 22 compounds from the positive ionization mode and 35 compounds from the negatif ionization mode. Compounds identified from the positive mode were dominated by amino acid groups, then compounds identified from the negatif mode were dominated by fatty acids and their derivatives. There were 35 metabolites that identified from the organ samples of the rat resulting subchronic toxicity test using the UHPLC Vanquish Tandem Q Exactive Plus Orbitrap HRMS method.Keywords: Justicia gendarussa Burm.f, rats, organ, metabolite profile
Enhancing the Knowledge and Skill of PKK and Karang Taruna Cadres in The Innovation of Mangosteen Fruit Products Suciati Suciati; Wiwied Ekasari; Andang Miatmoko; Neny Purwitasari; Lidya Tumewu; Yanu Andhiarto; Fatin Fadhilah Hasib; Tri Widiandani; Kholis Amalia Nofianti
Jurnal Pengabdian Masyarakat Vol 4 No 2 (2023): Jurnal Pengabdian Masyarakat
Publisher : Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpm.v4i2.1897

Abstract

Purpose: The current community service activities aim to provide knowledge and skills related to mangosteen and its processed products to the Songgon Village community Method: Transfer of knowledge and skill by lecturing and practice. Pre and post-tests were carried out to evaluate the participants’ knowledge before and after the workshop. Practical Applications: The knowledge and skill gained by PKK and Karang Taruna cadres in this workshop can be implemented in daily life. The participants learned how to make innovative products from mangosteen fruit so that it can be produced commercially. Thus, in the long term is expected to increase the income of Songgon Village Community. Conclusion: The results showed the participants' enthusiasm to participate in this activity, and the pre and post-tests demonstrated increased knowledge and skills. The next step requires intensive support for the Songgon Village community so that their products can be distributed commercially and provide economic benefits.
Co-Authors Achmad Fuad Hafid Andang Miatmoko Aristyawan, Andhika Dwi Armila Fatma Setyaningrum Aty Widyawaruyanti Bambang Prajogo EW Bian Dwi Cahyo Einstenia Kemalahayati Fatin Fadhilah Hasib Gunawan Indrayanto Gunawan Indrayanto Hanifa Rahma Putri Heny Arwaty Hidayati, Agriana Rosmalina Hilkatul Ilmi Idha Kusumawati Kholis Amalia Nofianti Lidya Tumewu Luthfiatu Kanina Marsih Wijayanti Neni Purwitasari Ni Putu Diah Parwita Sari Nindya Tresiana Noor Erma Nasution Sugijanto Noor Erma Nasution Sugijanto Noor Erma Sugijanto Nur Irhamni Sabrina Nuriha Marangoh Pratiwi Soesilawati Purwitasari, Neny Rakhmawati - - Retno Widyowati Rice Disi Oktarina Risma Pratiwi Silvy Juliana Subhan Rullyansyah Sudjarwo Sudjarwo Tri Widiandani Tutiek Purwanti Tutik Sri Wahyuni Wiwied Ekasari Yanu Andhiarto