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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Sumatera Medical Journal SCRIPTA SCORE Scientific Medical Journal Narra J Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Jurnal Pengabdian Mandiri The Journal of Society Medicine (JSOCMED) The Indonesian Journal of General Medicine Indonesian Journal of Global Health Research
Cut Putri Hazlianda
Departemen Dermatologi Dan Venereologi, Fakultas Kedokteran, Universitas Sumatera Utara, Medan, 20222, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary Other

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Bullous Pemphigoid in a Young Female: A Case Report Cut P. Hazlianda; Elza Wahyuni
Journal of Society Medicine Vol. 5 No. 8 (2026): August
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v5i8.291

Abstract

Introduction: Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease, mediated by autoantibodies against hemidesmosomal proteins BP180 and BP230, which activate the complement system, recruit eosinophils and neutrophils, and produce subepidermal bullae. Although BP typically affects older adults, it can occasionally arise in young patients, and prompt recognition and objective monitoring of disease activity are important. Case Description: A 22-year-old woman presented with a two-week history of pruritic, fluid-filled tense bullae over the trunk, axillae, forearms, palms, and thighs, which were unresponsive to topical betamethasone and cetirizine. Examination revealed tense, clear, and hemorrhagic bullae on erythematous macules with a negative Nikolsky’s sign, and the initial Bullous Pemphigoid Disease Area Index (BPDAI) was 23 (moderate). Histopathological examination revealed subepidermal bullae with eosinophil- and neutrophil-rich infiltrates, confirming the BP diagnosis. Laboratory testing revealed thrombocytopenia underlying the hemorrhagic lesions, and oral mucosal involvement was observed during follow-up. She was treated with systemic and topical corticosteroids, an antihistamine, and supportive care. The BPDAI progressively decreased to 17 at two weeks and 7 at three weeks, with no new lesions. Conclusion: Oral and topical corticosteroids were effective in treating moderate bullous pemphigoid in this patient. Serial BPDAI scoring provides a practical and objective measure of treatment response and supports timely dose adjustment.
PENYULUHAN KESEHATAN DAN PENCEGAHAN PENUAAN DINI KULIT WAJAH DI DESA BULU CINA Khairina Nasution; Nelva Karmila Jusuf; Muhammad Rusda; Dina Keumala Sari; Fauzi Budi Satria; Dina Arwina Dalimunthe; Deryne Anggia Paramita; Cut Putri Hazlianda; Raphaella Raphaella
JURNAL PENGABDIAN MANDIRI Vol. 5 No. 8 (2026): Agustus 2026
Publisher : Bajang Institute

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Abstract

Premature skin aging is a condition that not only affects aesthetic appearance but also has negative impacts on mental health, including decreased self-confidence and increased anxiety. Therefore, this community service activity aimed to provide education on skin health and the prevention of premature facial skin aging. The program was conducted by the Faculty of Medicine Universitas Sumatera Utara, in collaboration with Family Welfare Empowerment/ Pemberdayaan Kesejahteraan Keluarga (PKK) cadres in Bulu Cina Village, Hamparan Perak District, Deli Serdang Regency. The method used included a pretest administered before the educational session and a posttest conducted afterward to evaluate improvements in community knowledge. The results demonstrated a significant increase in the level of knowledge among PKK cadres regarding skin health and the prevention of premature facial aging. Continuous educational programs are recommended to further optimize community knowledge and awareness in maintaining skin health
Co-Authors Akmal, Mohammad Anis Astarina, Awalia Awalia Astarina Berlian, Guntur Dalimunthe, Dina A Dalimunthe, Dina A. Dhillon, Jesryn Diamanda, Ika Dina Arwina Dalimunthe Dina Arwina Dalimunthe, Dina Arwina Dina Keumala Sari Elza Wahyuni Fauzi Budi Satria Helen Anastasya Hutagalung, Patricia Ike Martyani Isma Aprita Lubis Jesryn Dhillon Kamaliah Muis Khairina Nasution Lubis, Flora M. Lubis, Flora Marita Molla Andriska Dewi Muhammad Rusda Nasution, Namira Afifah Nelva Karmila Jusuf Paramita, Deryne Anggia Putri Harahap, Rima Rahmi Putri, Desy Sahara Raphaella Raphaella Revinanda Venincia Pangaribuan Rina Amelia Rinda C. Risanti Risanti Rusdiana Rusdiana Salim, Stephanie Salsabila, Vanny Siahaan, Ade Gustina Sinaga, Riana M. Sinaga, Riana Miranda Sitepu, Josapat Bima Sakti