Nur Riviati, Nur
Division Of Geriatric, Department Of Internal Medicine, Faculty Of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia

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Journal : Damianus Journal of Medicine

The correlation between nutritional status and CD8+ cell counts in the elderly after the second COVID-19 vaccination in Palembang, Indonesia Khoirun Mukhsinin Putra; Nur Riviati; Eddy Mart Salim; Nova Kurniaty; Desti Paramita
Bahasa Indonesia Vol 21 No 3 (2022): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v21i3.3856

Abstract

Introduction: The SARS-CoV-2 virus is the cause of coronavirus illness (COVID-19). The WHO classified the outbreak a pandemic on March 9, 2020. The COVID-19 vaccine has been widely utilized to manage the pandemic. However, some high-risk conditions that can compromise the vaccine's efficacy require careful consideration. Patients over 60 years old are at a greater risk for COVID-19. Due to the involution of the thymus and the transformation of the cortex and medulla tissue into adipose tissue, CD8+ T cell numbers decline. In addition, undernutrition reduces the number of CD8+ T cells. The purpose of this study is to examine the relationship between nutritional status and CD8+ T cell counts in elderly patients following the second COVID-19 vaccination. Methods: This study is a pilot project employing a cross-sectional design. The sampling employed a technique of sequential sampling. On day 28, following the administration of the second vaccine, the Mini Nutritional Assessment (MNA) and the amount of CD8+ T cells in the blood were utilized to evaluate the nutrition status. Results: Between May and November of 2021, forty subjects were collected. The average number of CD8+ T cells was 517.32±41.67. Therefore, five people (12.5%) were at risk of malnutrition, whereas thirty-five (87.5%) had a normal nutritional status. Conclusion: There is a significant relationship between MNA and CD8+ levels (P<0.05) and a positive correlation between nutritional status and CD8+ T cell counts in the elderly who have received the second covid-19 vaccination in Palembang.
Korelasi Kadar Serum Albumin terhadap Massa, Kekuatan Otot dan Performa Fisik pada Usia Lanjut di Poliklinik Geriatri Rsmh Palembang Nur Riviati; Legiran; Irsan Saleh; Taufik Indrajaya; Surya Dharma; Muhammad Reagen; Fifi Yuniarti; Syafran Rasidi; Fadhyl Zuhry Lubis; Bima Indra
Bahasa Indonesia Vol 22 No 1 (2023): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v22i1.4233

Abstract

Introduction: Sarcopenia is a common problem found in the elderly. It is characterized by loss of muscle mass, muscle strength, and/or low physical performance. Currently, there’s little research on the association between serum albumin and muscle mass, muscle strength, and physical performance in the elderly, especially in Indonesia. This study aimed to find the correlation between serum albumin and muscle mass, muscle strength, and physical performance in the elderly. Method: A cross-sectional study was conducted from July 2022 to December 2022 towards elderly patients (>60 years) from the geriatric polyclinic at RSUP Moh. Hoesin Palembang. Serum albumin was examined for its correlation with muscle mass, muscle strength, and physical performance using Spearman’s test. Result: 41 elderly patients were included in this study (mean age 70.75 ± 7 years, 56.1% women). Correlation analysis showed that there’s a significant positive correlation between serum albumin with muscle strength (r=0.354, p=0.012) and a negative correlation with physical performance (r=-0.5, p <0.001). In comparison, there was no significant correlation between serum albumin and muscle mass (r=- 0.05, p=0.367). Conclusion: Muscle strength and physical performance have a significant correlation with serum albumin in the elderly. Therefore, even in the normal range, lower serum albumin is closely related to sarcopenia in the elderly. Key Words: albumin, muscle mass, muscle strength, physical performance, sarcopenia.
Co-Authors Afifah Z Salsabila Ahmad Rasyid Aidi A Putri Ali Ghanie Ali Zainal Abidin Ardesy Melizah Kurniati Ari Dwi Prasetyo Bima Indra Bintang A Prananjaya Cyntya Sari Sovianti Damai Trislinawati Desti Paramita Dibyantari, Ridzqie Dimas Ega Wijaya Putra Ditta Puspa Anggraini Djunaidi, Djunaidi Eddy Mart Salim Eddy Mart Salim Emirzon, M. Afif Baskara Erial Bahar Erial Bahar Erial Bahar Erwin Sukandi Fadhyl Zuhry Lubis Fifi Yuniarti Gultom, Widya Mandala Sari Hermansyah Hermansyah Indra, Bima Indrajaya, Taufik Irsan Saleh Irsan Saleh Iswadi Tanzil Jatmiko, Pandu Haryo Khoirun Mukhsinin Putra Khoirun Mukhsinin Putra Khoirun Putra kurniati, nova Legiran Legiran Legiran Mediarty, Mediarty Mgs Irsan Saleh Muhammad Erfin Muhammad Hadi Wijaya Muhammad Haryadi Ade Kurnadi Muhammad Irsan Saleh Muhammad Reagan Muhammad Reagen Mukmin, Sugianto Murdani Abdullah Muthia, Putri Nabila, Dewa Ayu Bulan Nelda Aprilia Salim Nova Kuniati Nova Kurniati Nova Kurniaty Noveldy Calzoum Bachry Octyvani Vani Perdana, Rizky Purwita W Laksmi, Purwita W RACHMAT HIDAYAT Rahmadini, Meirina Rini Nindela Rizki Bastari Rizky Perdana Rukiah Chodilawati Siti Setiati Sudarto Surya Darma Surya Darma Surya Dharma Syafran Rasidi Syamsu Indra Syamsu Indra Syarif Husin Syarif Husin Syarif Husin Syifa Alkaf Tanzil, Iswadi Taufik Indrajaya Taufik Indrajaya Taufik Indrajaya Tiar Marina Toruan, Theresia Lumban Tri Nisdian Wardiah Umi Partan, Radiyati Welly Salutondok Widya Mandala Sari Gultom Yuli Kurniawati, Yuli Yulia Farida Yahya Yulianto kusnadi Yuniza Yuniza Yuniza, Yuniza