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All Journal Indonesian Journal of Pharmaceutical Science and Technology As-syifaa Jurnal Farmasi Majalah Farmaseutik Jurnal Ilmu Alam dan Lingkungan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal of Pharmaceutical and Medicinal Sciences Fullerene Journal of Chemistry Pharmacoscript Yumary: Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Kefarmasian Jurnal Pengabdian Mandiri Media Farmasi E-Amal: Jurnal Pengabdian Kepada Masyarakat Jurnal Sains dan Kesehatan
Wahyu Hendrarti
Sekolah Tinggi Ilmu Farmasi Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary Other

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Aktivitas Antioksidan Ekstrak Etanol Batang, Daun Dan Akar Kopasanda (Chromolaena odorata L) dengan Metode ABTS (2,2’- azino - bis (3-etilbenzotiazolin -6- asam sulfonat) Astuti Amin; Soenandar Milian Tompunu Tengker; Wahyu Hendrarti
Jurnal Kimia Fullerene Vol 7 No 2 (2022): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37033/fjc.v7i2.428

Abstract

Kopasanda (Chromolaena odorata L.) is a plant that contains flavonoid compounds that can act as antioxidants. This study aims to determine the antioxidant potential of the ethanol extract of the stems, leaves and roots of kopasanda by looking at the IC50 value. The stems, leaves and roots of Kopasanda were extracted by maceration using 70% ethanol as solvent. The results of the antioxidant activity test using the ABTS method (2.2'- azino - bis (3 - ethylbenzothiazoline - 6- sulfonic acid) showed a very strong antioxidant activity with an IC50 value of 11.5380 g/ml leaves, 31.161 g/ml stems and 36,860 roots. g/ml with positive control of quarcetin obtained IC50 value of 1.698 g/ml. Based on these results, it can be concluded that the stems, leaves and roots of the encounter have very strong antioxidant activity against ABTS free radicals (2,2'- azino - bis (3 - ethylbenzothiazoline). - 6- sulfonic acid).
PEMBUATAN TEH HERBAL DARI TANAMAN SAMBUNG NYAWA Marwati Marwati; Asril Burhan; Muh. Azwar AR; Yuri Pratiwi Utami; Burhanuddin Taebe; Khairuddin Khairuddin; Hamdayani L. A; Fadillah Maryam; Reny Syahruni; Abd. Halim Umar; Imrawati Imrawati; Wahyuddin Wahyuddin; Wahyu Hendrarti
E-Amal: Jurnal Pengabdian Kepada Masyarakat Vol 2 No 2: Mei 2022
Publisher : LP2M STP Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47492/eamal.v2i2.1535

Abstract

Penggunaan ramuan obat tradisional sangat penting untuk dipahami pengelolaannya sampai menjadi produk sediaan secara rasional. Pengabdian ini bertujuan untuk menambah pemahaman terkait penggunaan obat tradisional yang dibuat dalam bentuk seduhan teh herbal dalam pengobatan penyakit diabetes melitus khususnya di daerah Baraya, Kota Makassar. Dalam pelaksanaan pengabdian ini dilakukan dengan cara ceramah secara langsung, diskusi, dan pemutaran video dalam pengolahan bahan baku sampai pembuatan teh herbal dari daun sambung nyawa. Dalam pengabdian ini, dipaparkan beberapa tanaman beserta kandungan kimia obat yang berpotensi farmakologis, pemanfaatan tanaman obat, serta bukti ilmiah yang telah diteliti. Antusias masyarakat juga sangat tinggi dalam berdiskusi dan berbagi pengalaman terkait penggunaan tanaman di masyarakat. Dalam pemutaran video pembuatan teh herbal juga memberikan penjelasan tentang cara pembuatan simplisia hingga menjadi produk herbal yang siap saji. Hasil dari pengabdian ini diharapkan masyarakat dapat mengaplikasikan ramuan dari tanaman obat keluarga dalam upaya pencegahan dan pengobatan penyakit diabetes melitus.
Evaluasi Penyimpanan Vaksin Pada Puskesmas Kabupaten Maros, Sulawesi Selatan paluseri, andi; Nurul Mufliha, Andi Naura; Hendrarti, Wahyu; Lukman Muslimin; Guntur, Muhammad
Media Farmasi Vol 20 No 1 (2024): Media Farmasi Edisi April 2024
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v20i1.260

Abstract

Evaluation of Storing Vaccines at the Community Health Center in Maros Regency, South Sulawesi Vaccines are a biological preparation whose storage requires special attention because they are compassionate. Improper storage and distribution of vaccines will reduce the quality of the vaccine so that its effectiveness will also decrease or even not be effective at all. This study aims to determine the description of vaccine storage at the Community Health Center, Regency of Maros, South Sulawesi. This research is a qualitative descriptive study conducted at 14 Community Health Centers in April - June 2022. Data was collected using direct interview techniques with vaccine officials and direct observation at vaccine storage areas. The research results show that the storage system meets the minimum requirements, although several aspects still do not meet the criteria due to a lack of storage facilities. Vaccines include vaccine solvent and vaccine layout in a refrigerator equipped with a generator, not exposed to direct sunlight, and in a room with sufficient air circulation. There are vaccine vial monitors (VVM) in conditions A and B. Incoming and outgoing vaccines are reported and recorded on the stock card. Likewise, the COVID-19 vaccine is also stored under reasonable control. So, it can be concluded that the vaccine storage system at 14 community health centers in the district. Maros has fulfilled the requirements of the Ministry of Health, Republic of Indonesia, No. 12 in 2017. Vaksin merupakan salah satu sediaan biologi yang penyimpanannya membutuhkan perhatian khusus karena sangat sensitif. Penyimpanan dan pendistribusian vaksin yang tidak tepat akan menurunkan mutu vaksin sehingga efektivitasnya juga menurun bahkan tidak berkhasiat sama sekali. Penelitian ini bertujuan untuk mengetahui gambaran penyimpanan vaksin di Puskesmas Kab. Maros, Sulawesi Selatan. Penelitian ini bersifat deskriptif kualitatif yang dilakukan terhadap 14 puskesmas pada bulan April hingga Juni 2022. Data dikumpulkan dengan teknik wawancara langsung pada petugas penanggung jawab vaksin dan melakukan observasi langsung pada tempat penyimpanan vaksin. Hasil penelitian menunjukkan bahwa sistem penyimpanan sudah memenuhi syarat minimal walaupun masih ada beberapa aspek yang tidak terpenuhi kriteria karena kurangnya fasilitas penyimpanan. Vaksin termasuk pelarut vaksin dan tata letak vaksin di dalam refrigerator yang dilengkapi dengan generator (genset), tidak terkena sinar matahari langsung, dan ruangan yang memiliki sirkulasi udara yang cukup. Terdapat vaccine vial monitor (VVM) yang berada dalam kondisi A dan B. Vaksin yang masuk maupun keluar terlapor dan tercatat pada kartu stok. Begitu pula dengan vaksin covid-19 juga tersimpan dengan kontrol yang baik pula. Sehingga dapat disimpulkan sistem penyimpanan vaksin pada 14 Puskesmas di Kab. Maros telah memenuhi syarat PerMenKes No. 12 tahun 2017.
Aktivitas Antioksidan Ekstrak Etanol Batang, Daun, dan Akar Kopasanda (Chromolaena odorata L.) dengan Metode FRAP (Ferric Reducing Antioxidant Power): Antioxidant Activity of Ethanol Extract of Stems, Leaves, and Roots of Kopasanda (Chromolaena odorata L.) with FRAP (Ferric Reducing Antioxidant Power) Method Astuti Amin; Nur Khairi; Wahyu Hendrarti
Jurnal Sains dan Kesehatan Vol. 4 No. 5 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i5.1271

Abstract

Kopasanda (Chromolaena odorata L.) is a plant that contains flavonoid compounds that can act as antioxidants. This study aims to determine the antioxidant potential of the ethanol extract of the stems, leaves and roots of kopasanda by looking at the IC50 value. The stems, leaves and roots of Kopasanda were extracted by maceration using 70% ethanol as solvent. The results of the antioxidant activity test using the FRAP (Ferric Reducing Antioxidant Power) method showed very strong antioxidant activity with IC50 values ??of leaves 23.4 µg/ml, stems 37.556 g/ml and roots 36.860µg/ml with positive control of quarcetin, IC50 values ??were 2.724 g/ml . Based on these results, it can be said that the stems, leaves and roots have very strong antioxidant activity against the reduction of FRAP (Ferric Reducing Antioxidant Power).
Edukasi Obat Tradisional dan Penyakit Diabetes Mellitus serta Hipertensi untuk Masyarakat Sidrap Abidin, Hamdayani Lance; Hapiwaty, Saldi; Ali, Alimuddin; Ningsih, Ririn Iriani; Tandiarrang, Lira; Hendrarti, Wahyu; Amin, Astuti
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 4 (2025): Juni
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v5i4.3716

Abstract

Purpose: The purpose of the Arga Math program is to introduce and implement the “Plakat” (Rank Number Board) as an innovative teaching aid to enhance students’ mathematical understanding, specifically in exponentiation. This visual tool aims to foster student engagement, simplify abstract concepts, and support teachers in creating more interactive and effective learning environments. Methodology/approach: The socialization activity was conducted at MTS Sinoa using a service-learning approach focused on knowledge transfer. The session began with a brief presentation on the concept and function of Plakat Teaching Aid. This was followed by hands-on practice, where participants applied the tool to solve exponent-related problems. Feedback and perceptions were collected through a structured questionnaire completed by teachers and students after the activity. Results/findings: The results of the activity showed that the Plakat teaching aid helped both teachers and students better understand exponentiation. Students demonstrated increased enthusiasm and confidence in solving exponential problems, while teachers acknowledged the usefulness of the tool in delivering abstract content. Furthermore, the activity motivated educators to design similar instructional media that aligned with curriculum objectives and encouraged creativity in teaching mathematics. Conclusions: The Arga Math Plakat proved to be an effective visual learning aid, making abstract mathematical concepts more accessible. It positively affects learning outcomes and inspires both students and educators. Limitations: The activity had limited reach due to time constraints and the participation of only 13 eighth-grade students, with minimal involvement from other educators. Contribution: This initiative supports educational innovation and contributes to achieving SDG Goal 4: Quality Education.
Studi Penggunaan Obat dan Assessment Pengobatan pada Kasus Acute Kidney Injury dan Chronic Kidney Disease di Rumah Sakit Area Makassar Pawallangi, Andi Nur'ainun Reskia; Hendrarti, Wahyu; Oktaviany, Ni Wayan; Rante, Melty; Rotinsulu, Pinkan Fabiola; Hasmira, Hasmira
Majalah Farmaseutik Vol 21, No 3 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v21i3.106951

Abstract

Acute Kidney Injury (AKI) dan Gagal ginjal akut (GGK) merupakan kondisi dengan morbiditas dan mortalitas tinggi, yang membutuhkan evaluasi terapi yang tepat akibat perubahan farmakokinetik dan farmakodinamik pada pasien. Penelitian ini bertujuan mengevaluasi penggunaan dan kesesuaian pengobatan pasien AKI dan GGK di rumah sakit wilayah Makassar, dengan desain studi observasional deskriptif retrospektif menggunakan data rekam medis Januari–Desember 2022. Sebanyak 179 pasien diteliti, terdiri dari 37 pasien GGA dan 142 pasien AKI. Terapi AKI banyak melibatkan pemberian cairan (NaCl 0,9%, Ringer Laktat), diuretik, dan nutrisi seperti Nephrosteril. Sebanyak 17 pasien AKI menunjukkan perbaikan fungsi ginjal berdasarkan kadar kreatinin dan BUN. Pada pasien GGK, 90,84% menggunakan antihipertensi, terutama golongan calcium channel blocker, loop diuretik, dan ARB. Sebanyak 66 pasien mencapai target tekanan darah (<140/90 mmHg), sementara 43 lainnya tidak tercapai, kemungkinan karena faktor usia, obesitas, konsumsi alkohol, ketidakpatuhan minum obat, dan penurunan eGFR. Secara umum, terapi sudah sesuai dengan pedoman KDIGO dan JNC 8, namun evaluasi berkala dan pendekatan individual tetap dibutuhkan untuk hasil pengobatan yang optimal.
Co-Authors Abd. Halim Umar Abdul Halim Umar Abidin, Hamdayani Lance Agustina Ma'tang Parinding Akbar Awaluddin Ali Djamhuri Alimuddin Ali Andi Nur Aisyah Andi Paluseri Andi Zulkifli AS Anggi Pebrianti Pasaribu Arfan Abu Bakar Asril Asril Burhan Asril Burhan Astuti Amin Burhanuddin Taebe Fadillah Maryam Fhahri Mubarak Hamdayani L. A Hamdayani Lance Abidin Hapiwaty, Saldi Hasmira, Hasmira Imrawati Imrawati Khairi, Nur Khairuddin Khairuddin Khairuddin Khairuddin Lukman Muslimin Maria Ulfa Marliana Pasang Marwati Marwati Marwati Marwati Maulita Indrisari, Maulita Michrun Nisa Muh Azwar AR Muhammad Guntur, Muhammad Ningsih, Ririn Iriani Nursamsiar Nursamsiar Nurul Mufliha, Andi Naura Nurul Wahyuni Oktaviany, Ni Wayan paluseri, Andi Pawallangi, Andi Nur'ainun Reskia Rante, Melty Reny Syahruni Rotinsulu, Pinkan Fabiola Sitti Rahimah, Sitti Sitti Ramlah Suwahyuni Suwahyuni Tandiarrang, Lira Tengker, Soenandar Millian Tompunu Wahyuddin Wahyuddin Wahyuddin Waode Syawal Lastri Yuri Pratiwi Utami Zulham Zulham