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Uji Efektifitas Ekstrak Daun Sirih Merah sebagai Anti Hiperglikemia pada Tikus Putih Diinduksi Aloksan Susanti, Try; Gusfarenie, Dwi; Nuraida, Nining
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 1 (2024): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i1.10427

Abstract

Diabetes melitus or diabetes is a health disorder in the form of a collection of symptoms that arise in a person caused by increased blood sugar leves due to insulin deficiency or insulin resistance and metabolic disorders in general. Red bete leaves contain chemical compounds of alkaloids, flavonoids, tannins and saponins which can lower blood sugar leves. The aim of this study was to determine the effectiveness of red bete leaf extract suspension (Piper crocatum) as antihyperglycemia in male white rats (Rattus novergicus) induced by alloxan. This research method is experimental. The extraction process for red bete leaves uses 70% ethanol solvent using the maceration method, then concentrated using a rotary evaporator and thickened using a water bath, then a suspension preparation is made, the doses given to male white rats are 2%, 4% and 6%. Glibenclamide suspension as a positive control and suspending agent as a negative control. The effectiveness of the red bete leaf extract suspension was seen from the reduction in blood sugar leves in mice after being induced by alloxan. The research data were analyzed using One Way ANOVA and paired sample t-test. The resuts of the study showed that red bete leaf extract suspension was effective as an antihyperglycemia, where the most effective dose was 6%. The suspension preparation of red bete leaf extract meets the requirements for evaluation of the preparation and stability of the preparation.
Development and Validation of a Critical Thinking Skills Instrument for Grade 11 Biology Students Based on Ennis’s Framework Try Susanti; Dwi Gusfarenie; Gusriani, Nanda; Diandara Oryza; Nining Nuraida
International Journal of Education and Teaching Zone Vol. 5 No. 1 (2026): February 2026 Edition
Publisher : Yayasan Nurul Yakin Bunga Tanjung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57092/ijetz.v5i1.546

Abstract

The ability to think critically is a key competency required of students in the 21st century, particularly in science education. This study aimed to develop and empirically evaluate a critical thinking skills assessment instrument for Grade 11 senior high school students in biology learning. The instrument was developed using the ADDIE development model, encompassing the analysis, design, development, implementation, and evaluation stages. Empirical testing was conducted during the implementation stage with Grade 11 senior high school students in Jambi City. Item analysis was performed to examine content validity, empirical validity, reliability, item difficulty, and discrimination indices. Empirical data were analyzed using ANATES version 4.0.9. The results indicated that 22 out of 56 items met the predefined validation criteria, demonstrating acceptable levels of item difficulty and discrimination power. The reliability coefficient of the finalized instrument was 0.68, which is considered acceptable for an exploratory educational assessment instrument. These findings suggest that the developed instrument possesses adequate psychometric properties for measuring students’ critical thinking skills in biology learning and can support future instructional evaluation and research within similar educational contexts.