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All Journal Biotika: Jurnal Ilmiah Biologi Jurnal SOLMA IRJE (Indonesian Research Journal in Education) Jurnal Biotek Bioscientist : Jurnal Ilmiah Biologi EDU-BIO : Jurnal Pendidikan Biologi Biodik: Jurnal Ilmiah Pendidikan Biologi
Dwi Gusfarenie
UIN Sulthan Thaha Saifuddin Jambi
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Neuroscience Social Sciences Other

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Uji Efektifitas Ekstrak Daun Sirih Merah sebagai Anti Hiperglikemia pada Tikus Putih Diinduksi Aloksan Susanti, Try; Gusfarenie, Dwi; Nuraida, Nining
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 1 (2024): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i1.10427

Abstract

Diabetes melitus or diabetes is a health disorder in the form of a collection of symptoms that arise in a person caused by increased blood sugar leves due to insulin deficiency or insulin resistance and metabolic disorders in general. Red bete leaves contain chemical compounds of alkaloids, flavonoids, tannins and saponins which can lower blood sugar leves. The aim of this study was to determine the effectiveness of red bete leaf extract suspension (Piper crocatum) as antihyperglycemia in male white rats (Rattus novergicus) induced by alloxan. This research method is experimental. The extraction process for red bete leaves uses 70% ethanol solvent using the maceration method, then concentrated using a rotary evaporator and thickened using a water bath, then a suspension preparation is made, the doses given to male white rats are 2%, 4% and 6%. Glibenclamide suspension as a positive control and suspending agent as a negative control. The effectiveness of the red bete leaf extract suspension was seen from the reduction in blood sugar leves in mice after being induced by alloxan. The research data were analyzed using One Way ANOVA and paired sample t-test. The resuts of the study showed that red bete leaf extract suspension was effective as an antihyperglycemia, where the most effective dose was 6%. The suspension preparation of red bete leaf extract meets the requirements for evaluation of the preparation and stability of the preparation.
EFEK PEMBERIAN KOPI ROBUSTA, ARABIKA, DAN LIBERIKA ASAL JAMBI TERHADAP KINERJA MEMORI SPASIAL MENCIT (Mus Musculus) YANG DIINDUKSI ETANOL Oktaviani, Widia Bela; Gusfarenie, Dwi; Riany, Hesti
BIOTIKA Jurnal Ilmiah Biologi Vol 24, No 1 (2026): BIOTIKA JUNI 2026
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/biotika.v24i1.67179

Abstract

Alkoholisme menjadi penyebab utama morbiditas dan mortalitas global. Etanol menurunkan memori spasial melalui peningkatan ROS di hipokampus, sedangkan antioksidan kopi berpotensi memperbaiki gangguan kognitif tersebut. Penelitian ini bertujuan mengevaluasi efektivitas kopi robusta, arabika, dan liberika asal Jambi terhadap kinerja memori spasial mencit (Mus musculus) yang diinduksi etanol. Penelitian menggunakan desain eksperimen laboratorium post-test only dengan 25 mencit galur Swiss Webster yang dibagi menjadi lima kelompok: kontrol (tanpa etanol dan kopi), EtOH (etanol tanpa kopi), EL (etanol + kopi liberika), EA (etanol + kopi arabika), dan ER (etanol + kopi robusta). Analisis kinerja memori spasial diukur berdasarkan persentase Spontaneous Alternation (SA) selama 21 hari pemberian kopi dan etanol pada mencit. Etanol diberikan secara bertingkat dengan konsentrasi 3%, 6%, 10%, dan 20%, dan dosis kopi disesuaikan dengan berat badan mencit. Data dianalisis secara parametrik menggunakan uji One-way ANOVA dan dilanjutkan dengan uji post hoc Bonferroni dan uji Games-Howell (p<0,05). Hasil penelitian menunjukkan terjadi penurunan kinerja memori spasial pada mencit yang diinduksi etanol pada seluruh kelompok mencit perlakuan. Setiap jenis kopi dapat meningkatkan kinerja memori spasial bergantung pada lamanya induksi. Peningkatan paling konsisten terjadi pada kopi Liberika hingga hari ke-21. Secara umum, pemberian kopi menekan penurunan memori spasial akibat etanol, dengan efek terbaik pada kopi Liberika.Kata kunci: Etanol; Kopi; Memori Spasial.
Project-based digital portfolio: Biology assessment and learning innovation to improve student competency Gusfarenie, Dwi; Nuraida, Nining; Suraida, Suraida
Indonesian Research Journal in Education |IRJE| Vol. 10 No. 2 (2026): IRJE |Indonesian Research Journal in Education
Publisher : Universitas Jambi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/irje.v10i2.50239

Abstract

This study aims to develop and evaluate the effectiveness of a project-based digital portfolio, BioPorta, as an assessment and learning medium in the Medicinal Plants course for biology students. The research employed a research and development (R&D) approach using the ADDIE model, which includes analysis, design, development, implementation, and evaluation stages. The product was validated by media and material experts, achieving high validity scores of 86.06% and 94%, respectively. Practical testing showed positive results, with scores of 90% from lecturers, 77.06% from small group trials, and 86.18% from field tests. The effectiveness test using N-gain analysis indicated a significant improvement in student learning outcomes, with a score of 0.805 in the experimental class compared to 0.225 in the control class. These findings demonstrate that BioPorta is a valid, practical, and effective tool for enhancing student competence, engagement, and learning outcomes through project-based digital learning.
Co-Authors Ali Murtadlo Andesmora, Evan Vria Anisia, Ica Wandari Aprianto, Riko Chatib, Muhsin Darma Putra Gusriani, Nanda Hasibuan, Maimunah Permata M Husaini Ma’aruf, Reza Nining Nuraida Nofriadi, Nanang Novallyan, Devie Oktaviani, Widia Bela Rahmat Hidayat Rahmi, Miftahur Redita Nur Aini Reny Safita Reny Safita Reny Safita Riany, Hesti Rika Kitri Ardianti Rita Simatupang Saputra, Dalli Yulio Sari, Defita Permata Siti Nuraisyah Sumitro Sumitro Suraida Suraida Syahmi, Wahilman Tomi, Dodo Tri Setia Try Susanti Try Susanti