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All Journal Adi Widya : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Manuntung Jurnal Farmasi Indonesia Jurnal Biomedika Jurnal Kefarmasian AKFARINDO JURPIKAT (Jurnal Pengabdian Kepada Masyarakat) Jurnal Farmasi dan Sains Indonesia (JFSI) Indonesian Journal of Pharmaceutical Education Jurnal Mitra Pengabdian Farmasi
Dewi Ekowati
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Indonesian Journal of Pharmaceutical Education

 1 
Formulating Oil Emulgel of Nyamplung (Calophyllum inophyllum L) with Variations of HPMC and Activity Testing for Incision in Rabbit New Zealand Erinda Risma Puspita Cahya; Dewi Ekowati; Dwi Ningsih
Indonesian Journal of Pharmaceutical Education Vol 2, No 3 (2022): September-Desember 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i3.15455

Abstract

Emulgel is an emulsion of both O/W and W/O which is made into a gel by mixing it with a gelling agent. One of the gelling agents that is often used is HPMC because it can produce a clear gel, easily soluble in water, and has low toxicity. Nyamplung oil has wound healing activity by stimulating cell proliferation and the production of collagen and GAG (glycosaminoglycans). The purpose of this study was to find out that nyamplung (Calophyllum inophyllum L) oil can be made into a good emulgel preparation, has the effect of healing cuts, to determine the effect of variations in HPMC concentration on the physical quality and stability of the emulgel, and in accelerating the healing of cuts. This study used three formulas containing 1%, 2%, and 3% HPMC plus one control formula. Emulgel is made by mixing emulsion with gel and contains 1% nyamplung oil, then physical quality tests are carried out : organoleptic, homogeneity, pH, adhesion, dispersibility, viscosity test, emulgel type test, stability test. The wound healing activity test was carried out on the back of New Zealand rabbits. The percentage of treatment results were statistically analyzed. The results showed that all nyamplung oil emulgel formulas could be made ini emulgel preparations, had good physical quality and stability and had the effect of wound healing. The effect of gelling agent concentration affects the speed of wound healing. The result of the most optimal wound healing activity test is the formula 2.
Activity Tests Of Sunscreen Emulgel Preparation of Tamanu Oil (Calophyllum inophyllum L.) Combined With Titanium Dioxide (TiO2) Ni Wayan Devy Indah Lestari; Reslely Harjanti; Dewi Ekowati
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.21225

Abstract

Sunlight is the main source of UV rays, exposure to UV rays can have a negative impact on human skin. These negative impacts can be prevented by using sunscreen. The effectiveness of sunscreen can be increased by combining UV filters and natural ingredients. This study aims to determine variations in the concentration of tamanu oil (Calophyllum inophyllum L.) in an emulgel preparation of a combination of tamanu oil and TiO2 which can provide protection as a Sun Protection Factor (SPF) with good physical quality and stability.Tamanu oil is made in 3 concentration variations of 10%; 15%; and 20% and combined with 7% titanium dioxide. Emulgel preparations as a whole were tested for physical quality and stability tests were carried out using the cycling test method. Testing of sunscreen activity in preparations was carried out in vitro using a UV-Vis spectrophotometer at a wavelength of 290-320 nm. The research results were processed statistically.The results of the sunscreen activity test for the emulgel preparation, a combination of tamanu oil and TiO2, showed that all formulas had activity as a sunscreen. The highest SPF value of the emulgel combination of tamanu oil and TiO2 was in formula 6 (20% oil and TiO2) of 9.6 and after the stability test the SPF formula 6 (20% oil and TiO2) was 9.0.
Co-Authors Ahmad Nuzulul Abid Aljufri Mahmud Annisa Ratna Fadilla Purba Argo Widianto Astiti Noer Cahyati Desi Purwaningsih Desti Nuryani Sitompul Dwi Ningsih Dwi Ningsih Dwi Ningsih Dyah Ayu Setyowati Endang Sri Rejeki Endang Sri Rejeki Erinda Risma Puspita Cahya Evie Yuliaswari Ignatius Yuli Yudhianto Ika Andriana Ika Purwidyaningrum Inaratul Rizkhy Hanifah Ismi Maksalmina Iswandi Jason Merari Peranginangin Jawi Prastiyani Keswara, Yane Dila Khofifah Maharani Kurniasari, Fitri Mimiek Murrukmihardi Mohammad Febry Andintias Narimo Ni Wayan Devy Indah Lestari Ningsih, dwi - Prayoga Fery Yuniarto Rahmawati, Ismi Rahmawati, Ismi - Reslely Harjanti Robuta, Marrsa Rojwaanna Rodhi Anshari Sri Rejeki Handayani Sri Rejeki Handayani, Sri Rejeki Sunarti Sunarti Syamsul Arifin Tri Wijayanti Tri Wijayanti Triyani Triyani Wicaksono, Salsabila Melia Putri Yurita Werdiningsih Hutami