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Oktira Roka Aji
Program Studi Biologi, FAST, Universitas Ahmad Dahlan
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Journal : Jurnal Sains dan Teknologi

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Aktivitas Antibakteri Ekstrak Daun Rivina humilis L. Terhadap Staphylococcus aureus dan Pseudomonas aeruginosa Yuliani, Ririn Kholifatu; Ilma, Nur Malika; Tufahati, Nadhira; Salimah, Azizah Zahratus; Aji, Oktira Roka
JST (Jurnal Sains dan Teknologi) Vol. 14 No. 1 (2025): April
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jstundiksha.v14i1.93228

Abstract

Rivina humilis (getih-getihan) is a wild plant that contains bioactive compounds that have the can to be used as antibiotics. This study aims to determine the antibacterial activity of ethanol extract of getih-getihan leaves against Staphylococcus aureus (Gram positive) and Pseudomonas aeruginosa (Gram negative) bacteria through in vitro experimental research. The subject used in the study was getih-getihan (Rivina humilis) leaves which were fresh and good without any disease. Data collection methods were carried out through laboratory experiments including extraction, metabolic analysis using LC-HRMS, antibacterial testing using disc diffusion, MIC and MBC. Data were analyzed using ANOVA and Duncan's post-hoc test with a significant value of p<0.05. The results of ethanol extract of getih-getihan leaves showed flavonoids, phenols, triterpenoids, amino acids, fatty acids, and carboxylic acids. The extract is can to inhibit and kill both bacteria, which is indicated by the presence of an inhibition zone, a decrease in absorbance, and no colony growth on the test media. In conclusion, ethanol extract of getih-getihan leaves has antibacterial activity against S. aureus and P. aeruginosa. The implication is that ethanol extract of getih-getihan leaves has the potential to be developed as a natural antibacterial agent that supports alternative treatment against bacterial infections against S. aureus and P. aeruginosa.
Co-Authors Abdul Aziz Adz-Dzikir, Fatihatuljannah Aisyah, Iis Nisya Nur Al Farisi, Irsyad Andika Bayu Chandra Aninda Kumala Sari Ardi, Subhan Zul ARUM PATRIATI Astuti, Sutan Nur Chamida Tri Azizah, Mar'atul Cahya Ningsih, Ayu Cucu Cahyanti Diah Asta Putri Diah Asta Putri Diah Asta Putri Diah Asta Putri DYSHELLY NURKARTIKA PASCAPURNAMA EDY GIRI-RACHMAN PUTRA Efrida Siti Alifia Ega Asnatasia Maharani ERNAWATI ARIFIN GIRI-RACHMAN Falih, Afifah Nurul FENRYCO PRATAMA Fitria, Karomah Indah Handayani, Erisa Budi Hartanto, Dody Haryadi, Bagus Hasna Chaerani Zakkiyah Hidayah, Hidayah IHSANAWATI IHSANAWATI Ihsani, Nisa Ika Maryani Ilma, Nur Malika Imelda Pangaribuan Inggita Utami Irsalinda, Nursyiva Irvanita, Deva Anggun Jannati Aulah Jinan, Rifa Fatma Kurnia, Dhiffa Trisna Laila, Alfiatul Larasati Haliimah Roosyidah Lestari, Iva Dita MAELITA RAMDANI MOEIS MAELITA RAMDHANI MOEIS Maliza, Rita Mardiah, Irma Merlia Rahma Tari Nofa Nur Fiani Nora Bastiani Nugraha, Farhan Satya Nur Azizah Nur Azizah Nuraisyah Binte Zainal Nurul Suwartiningsih Pinasti, Vanya Aurel Pratiwi, Ambar Pratiwi, Ambar Puguh Wahyu Prasetyo, Puguh Purwanti Pratiwi Purbosari Puspitarini, Sofia Putri , Diah Asta Putri, Anas Tasya Putri, Aulia Ramanda Putri, Diah Asta Putri, Nida’a Fauziyyah Rinaldi Rizal Putra Riris Asyhar Hudaya Rohmantin, Dita Rossa Puteri Baharie, Sri Safitri, Salsabila Salimah, Azizah Zahratus Santrianda, Aldhiani Silfi Pratiwi Sri Wahyuni Sri Wahyuni Sumbudi, Milliniawati Suwartiningsih, Nurul Suwartiningsih, Nurul Tri Puspita Sari Tufahati, Nadhira Umi Salamah Vianingtyas, Naresh Wari Mega Wachid Eko Purwanto Wicaksono, Adelyanty Pangestuty Wulandari, Endah Retno Yudi Ari Adi, Yudi Ari Yuliani, Ririn Kholifatu Zahra, Safa Auli Zakkiyah, Hasna Chaerani Zul Ardi, Subhan