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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Kimia Riset Jurnal Ilmiah Kedokteran Wijaya Kusuma THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Ilmiah Soulmath : Jurnal Edukasi Pendidikan Matematika Jurnal Mandala Pharmacon Indonesia Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Medical Technology and Public Health Journal Sains dan Matematika Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Abdimas Berdaya : Jurnal Pembelajaran, Pemberdayaan dan Pengabdian Masyarakat Jurnal Abdimas Kartika Wijayakusuma Indonesian Journal of Innovation Studies Procedia of Social Sciences and Humanities Prosiding SEMNAS INOTEK (Seminar Nasional Inovasi Teknologi) Jurnal Laboratorium Khatulistiwa International Journal Multidisciplinary Oshada Jurnal Teknologi Laboratorium Medik Borneo Jurnal Sains, Teknologi dan Kesehatan Manajemen Pelayanan Kesehatan Indonesian Journal Health Science and Medicine Jurnal Analis Kesehatan Kendari Academia Open
Chylen Setiyo Rini
Prodi Teknologi Laboratorium Medis, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Sidoarjo
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Potensi Antibakteri Madu Multiflora dan Bee Pollen dari Lebah Madu Eropa (Apis mellifera) dalam Menghambat Pertumbuhan Cutibacterium acnes Jannah, Vita Wardah Nur; Rini, Chylen Setiyo
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.964

Abstract

Jerawat adalah kondisi kulit di mana pori-pori tersumbat oleh minyak dan sel kulit mati, serta aktivitas bakteri C. acnes. Madu multiflora dan bee pollen merupakan produk lebah yang mengandung senyawa bioaktif dan memiliki sifat antibakteri. Penelitian ini menggunakan teknik difusi cakram dengan pengulangan sebanyak tiga kali (n=3) dengan konsentrasi 25% b/v, 50% b/v, 75% b/v, dan 100% b/v untuk madu dan bee pollen, serta kombinasi dengan perbandingan 1MM:3BP, 1MM:1BP, 3MM:1BP, tetrasiklin 50 mg/ml sebagai kontrol positif dan aquades steril sebagai kontrol negatif. Hasil menunjukkan bahwa madu, bee pollen, dan kombinasinya memiliki potensi antibakteri terhadap pertumbuhan C. acnes. Madu multiflora dan bee pollen memiliki penghambatan terkuat pada konsentrasi 100%, yaitu 27,71 mm (kategori kuat) untuk madu multiflora dan 18,26 mm (kategori sedang) untuk bee pollen. Kombinasi 3MM:1BP memberikan zona hambat tertinggi sebesar 29,81 mm (kategori kuat) dan menunjukkan hasil yang lebih efektif dibanding madu, bee pollen, dan kombinasi lainnya.
Table Salt Shows Stronger Antibacterial Activity Against Oral Pathogens: Garam Meja Menunjukkan Aktivitas Antibakteri yang Lebih Kuat Terhadap Patogen Mulut Bima Arya Nugraha; Chylen Setiyo Rini
Academia Open Vol. 10 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.8699

Abstract

General Background: Oral hygiene is necessary to prevent microbial growth, and salt solutions are widely used as natural antibacterial agents. Specific Background: Table salt and Himalayan black salt are commonly used in oral care, but their antibacterial activity at different concentrations requires comparison. Knowledge Gap: Comparative in-vitro evaluation of both salts against oral pathogenic bacteria across multiple concentrations remains limited. Aims: This study compares antibacterial activity of table salt and Himalayan black salt solutions at concentrations of 5%–25% against Streptococcus mutans and Klebsiella pneumoniae using disc diffusion testing. Results: Table salt at 15% produced very strong inhibition against Streptococcus mutans, while Himalayan black salt at 25% showed moderate inhibition. Against Klebsiella pneumoniae, table salt at 20% and Himalayan black salt at 25% demonstrated moderate inhibition. Two-way ANOVA showed significant differences between salt types, while post hoc analysis showed no significant differences among concentrations. Novelty: This study provides graded concentration comparison of two salt types using repeated diffusion testing. Implications: The findings support table salt solution as a natural antibacterial option for oral hygiene and provide laboratory-based reference for natural antimicrobial materials. Highlights: Concentration 15% Solution Produced the Strongest Inhibition Zone Against Cariogenic Bacteria. Diffusion Testing Demonstrated Measurable Bacterial Growth Suppression Across Multiple Treatment Levels. Statistical Comparison Confirmed Distinct Antibacterial Responses Between Both Mineral Solutions. Keywords: Table Salt, Himalayan Black Salt, Streptococcus Mutans, Klebsiella Pneumoniae, Antibacterial Activity
ANALISIS DAYA HAMBAT EKSTRAK KUKUS DAN INFUSA LABU KUNING (Cucurbita Moschata) TERHADAP PERTUMBUHAN Escherichia coli Chylen Setiyo Rini; Fransiska Saputri Leing
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2026): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v3i2.2512

Abstract

Diarrhea is a disease caused by pathogenic microorganism infections, one of which is E.coli, which is a serious problem because it can cause death. One alternative treatment utilizes natural ingredients. This experimental study aims to test the effectiveness of pumpkin (C.moschata) extract processed using the steaming and infusion methods on the growth of E. coli bacteria. The yellow squash samples used were sourced from the Larangan market in Sidoarjo, with criteria of freshness and yellow color. The inhibition test was conducted using the Kirby-Bauer method, repeated three times, with extract concentrations of 25%, 50%, 75%, and 100%, a positive control of chloramphenicol, and a negative control of sterile distilled water. The results showed that all extracts exhibited increased antibacterial activity with increasing concentration, with the largest inhibition zone at a concentration of 100%, namely 12.55 mm for steamed pumpkin flesh and 11.61 mm for steamed pumpkin seeds.
Analysis of Acid-Fast Bacilli (AFB) Conversion at the 2nd and 5th Months in Tuberculosis Patients with and without Diabetes Mellitus Chylen Setiyo Rini; Sukma Nilawati
Jurnal Laboratorium Khatulistiwa Vol 9, No 2 (2026): MEI 2026
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i2.2128

Abstract

Tuberculosis (TB) remains a major global health problem and is often associated with comorbidities such as Diabetes Mellitus (DM). DM can impair immune response and may delay sputum smear conversion during TB treatment. This study aimed to analyze the difference in Acid-Fast Bacilli (AFB) smear conversion at the 2nd and 5th months between TB patients with DM and those without DM. This study used a descriptive comparative design with secondary data from TB patients recorded in 2023–2024 at the Sepulu Community Health Center Laboratory, Bangkalan, Madura. A total of 117 patients met the inclusion criteria. Data were analyzed using the Chi-square test with SPSS version 25. The results showed a significant difference in AFB smear conversion between TB-DM and TB non-DM patients. At the 2nd month, a significant difference was found (p < 0.001). Similarly, at the 5th month, a significant difference was observed (p = 0.009). TB patients with DM tended to experience slower sputum smear conversion compared with patients without DM. These findings indicate that Diabetes Mellitus may influence the effectiveness of TB treatment, particularly in the sputum conversion phase.
Co-Authors AA Sudharmawan, AA Absari, Eki Puji Ade Teti Vani Aini, Aqiliyanti Nur Aisyah Putri, Aprilia Akbar, Aulia Rizky Fadhillah al-akbar, Wildan Alhafiz, Rafaiz Filaili Ambarani, Putri Yuli Andika Aliviameita Anggraeni, Rifka Wahyu Anugraheni Anugraheni Azzahra, Aulia Bayu Hari Prasojo Bima Arya Nugraha Devi Arvindani Masyitha Fifi Isti Tamtyas Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fransiska Saputri Leing Galuh Ratmana Hanum Hartin, Ellyce Huesein, Ida Agustini Saidi Imamah, Siti Aliyatul Jamilatur Rohmah Jannah, Vita Wardah Nur Juliana, Tiara Karlia Hedit Tiana Kimberly, Bella Tasya Liany, Ayundah Novie Lidyaningrum, Galuh Ajeng Lindawati, Sari Liyaajul, Pratasyah Makhnunah, Makhnunah Miftahul Mushlih MUFIDAH, LAILATUL Mukarromah, Rizka Aisya Mustar Nisak, Khairun Nugroho, Rhenald Aditya NUR EFENDI Nuril Lutvi Azizah Oktaruliawan, Veronika Ony Wibriyono Angkejaya Pratiwi, Nova Linda Purwanti, Yanik Puspitasari Puspitasari Puspitasari Puspitasari Puspitasari Putri, Wafiq Zahro Rahmawati, Vifin Putri Ribangun Bamban Jakaria Saputra, Eduwardo Roy Sari, Azizah Krismonita Setyaputri, Nabila Hani SITI CHOLIFAH Sofi Rahayu, Bella Sukma Nilawati Sukmawati Sukmawati Tis’iyyah , Siti Nur Maghfiroh Tri Chahyani Rahmawati Putri Wahyudi, Eko Bambang Widyaningrum, Leni Yuroh Yeninastiti, Reny Zulfida Ainindiyah Putri Purwanto