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All Journal Journal of Mathematical and Fundamental Sciences JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Mandala Pharmacon Indonesia Jurnal Pengabdian Masyarakat Indonesia SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Jurnal Pengabdian Masyarakat Dharma Andalas Sahabat Sosial: Jurnal Pengabdian Masyarakat
Nofrizal
Program Studi Farmasi, Universitas Dharma Andalas, Indonesia
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 1 
Isolation and Antibacterial Properties of Phenyl Acrylic Acid Derivatives from Balanophora elongata Blume Nanda Putra; Goldha Faroliu; Nova Syafni; Nofrizal; Amri Bakhtiar; Dayar Arbain
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.5

Abstract

Balanophora elongata (Balanophoraceae) is a tropical parasitic flowering plant 9 cm in height. Four known phenyl acrylic acid derivatives, methyl caffeate (1), caffeic acid (2), 1,6-di-O-caffeoyl-β-D-glucopyranose (3), and coniferin (4), were isolated from this plant. Structural elucidation of the isolated compounds was determined by IR, LC-ESI-MS, 1D and 2D NMR.  Extracts and isolated compounds were tested toward some standard human pathogenic bacteria using the agar disk diffusion method. Their inhibition zones were compared to that of chloramphenicol as positive control. Compound 1 showed inhibition toward Streptococcus mutans, while compound 3 and 4 inhibited Staphylococcus aureus.
Konseling Penggunaan dan Pembagian Multivitamin Gratis pada Masa Pandemi Covid-19 di Kelurahan Piai tangah Kota Padang Rosiana Rizal; Helmice Afriyeni; Sefrianita Kamal; Sara Surya; Mesa Sukmadani Rusdi; M. Rifqi Efendi; Nofrizal; Afriyani
Jurnal Pengabdian Masyarakat Indonesia Vol 2 No 2 (2022): JPMI - April 2022
Publisher : CV Infinite Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jpmi.383

Abstract

Indonesia telah menerapkan Pembatasan Sosial Berskala Mikro (PPKM) sebagai respon terhadap peningkatan kasus Covid-19. Menurut tim tracing kelurahan Piai tangah dari bulan Juli tahun 2021, terjadi peningkatan jumlah kasus reaktif dan positif Covid-19 di kelurahan Piai Tangah yang terletak di Kota Padang. Oleh karena itu, pengabdian ini bertujuan untuk mencegah penyebaran infeksi covid-19 di wilayah ini. Metode pengabdian yang dilakukan di masyarakat antara lain pembagian multivitamin, pemberian informasi tentang Covid-19, seperti gejala infeksi dan cara pencegahannya, serta penyuluhan penggunaan multivitamin untuk meningkatkan derajat kesehatan masyarakat Piai Tangah di kecamatan Pauh yang terletak di kota Padang. Hasil kegiatan pengabdian ini sangat diminati masyarakat karena memenuhi kebutuhan kesehatan masyarakat Piai Tangah yang terpapar Covid-19 dengan mendapatkan multivitamin sebagai peningkatan sistim imun terhadap covid-19. Selain itu, terdapat respon positif dari masyarakat yang meyakini bahwa kegiatan pengabdian diperlukan untuk meningkatkan daya tahan tubuh, dimana mayoritas (75%) memahami gejala dan tindakan pencegahan Covid-19, serta cara mengkonsumsi multivitamin dengan tepat dan benar dari konseling yang dilakukan.
Penyuluhan Pemanfaatan Minyak Atsiri Cengkeh dan Serai sebagai Aromaterapi Aplikasi Parfum Masker Lusia Eka Putri; Rustini Rustini; Sefrianita Kamal; Sara Surya; Rosiana Rizal; Nofrizal Nofrizal; Nurunnisa Aprilya Yulfi; Widia Rahma Putri; Laras Alhabil
Jurnal Pengabdian Masyarakat Dharma Andalas Vol 1 No 1 (2022): Jurnal Pengabdian Masyarakat Dharma Andalas
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (782.921 KB) | DOI: 10.47233/jpmda.v1i1.609

Abstract

Indonesia is one of the countries that has the potential as a producer of essential oils. Plant parts that can be used as a source of essential oils are the roots, stems, leaves, flowers, and so on. In the midst of the current pandemic, where the number of COVID-19 cases is increasing day by day. This requires us to maintain our immune system and always comply with health protocols, one of which is the use of masks. The use of the mask for more than 4-5 hours will cause an unpleasant odor. The outreach activity on the use of essential oils of citronella and cloves as aromatherapy in the application of perfume masks is an alternative that can be used by the public to overcome the negative impacts of using masks that last more than 4-5 hours. With this outreach activity, it is hoped that the community can apply, implement and stay healthy in the midst of the epidemic that hit. In maintaining endurance, we must relax ourselves so that we can foster creativity and remain productive in carrying out daily activities.
Penyuluhan Gangguan Saluran Cerna Kamal, Sefrianita; Serdiani, Serdiani; Surya, Sara; Putri, Lusia Eka; Fauzan, Adrul; Dwinatrana, Khiky; Usman, Hendrizal; Nofrizal, Nofrizal
Jurnal Pengabdian Masyarakat Dharma Andalas Vol 3 No 1 (2024): Jurnal Pengabdian Masyarakat Dharma Andalas
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Counseling or counseling on gastrointestinal disorders by pharmacists can include a variety of services that focus on pharmaceutical aspects and drug management. Pharmacists play an important role in ensuring patients receive optimal pharmaceutical care in a home environment known as Home Care, in accordance with the Tri Dharma Perguruan Tinggi vision and mission of Universitas Dharma Andalas which makes its students Interpreneur. The purpose of this service is for students to be able to develop interpreneurship talents in themselves, with counseling and education techniques that will later become provisions when graduating into business opportunities and are able to create jobs. This counseling was carried out at SMK Kartika 1-2 and SMK Pratama Padang. It is hoped that through this counseling, students will be wise in managing their own health, especially those related to gastrointestinal disorders
Edukasi Penggunaan Antibiotik Dan Peduli Resistensi Antibiotik Pada Masyarakat Kota Padang Surya, Sara; Putri, Lusia Eka; Usman, Hendrizal; Nofrizal, Nofrizal; Dwinatrana, Khiky; Kamal, Sefrianita
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 2 No. 1 (2023): Sahabat Sosial: Jurnal Pengabdian Masyarakat (Desember)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v2i1.244

Abstract

Antibiotics are drugs used to prevent and treat infections caused by bacteria. People mistakenly assume that antibiotics cure all diseases and are not careful in consuming or providing complete antibiotic therapy. Inappropriate use of antibiotics can increase medical costs because resistance makes the drugs more toxic. This Community Service activity aims to provide knowledge about the proper and correct use of antibiotics, providing knowledge about antibiotic resistance. This service activity is carried out by providing education and also providing leaflets about the use of antibiotics and antibiotic resistance. This activity was carried out by GOR H. Agus Salim, Padang City. The results of the activity where the number of participants was 80 people, there were still some who did not understand how to use drugs and antibiotic resistance. The activity was carried out by 6 lecturers assisted by 6 students from the Pharmacy Study Program at Dharma Andalas University. From this service activity, it is hoped that the people of Padang City will receive education about the use of antibiotics and be aware of the dangers of antibiotic resistance.
Sosialisasi Tanaman Obat Tradisional dan Penyuluhan Terapi Jerawat pada Siswa SMA di Pariaman Serdiani, Serdiani; Kamal, Sefrianita; Nofrizal, Nofrizal; Surya, Sara; Putri, Lusia Eka; Azzahra, Rafifah; Elsandra, Yesi; Usman, Hendrizal; Fauzan, Adrul; Nandayasa, Wira Wahyudi; Ilhami, Restu Wahyudi; Wahyu, Yazid Zidani; Rahmat, Albiya; Sari, Dian Permata
Jurnal Pengabdian Masyarakat Dharma Andalas Vol 3 No 2 (2025): Jurnal Pengabdian Masyarakat Dharma Andalas
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jpmda.v3i2.1936

Abstract

Tanaman obat tradisional memiliki potensi besar sebagai alternatif pengobatan alami yang terjangkau, namun penggunaannya perlu didukung penelitian dan edukasi yang tepat. Pengetahuan masyarakat bervariasi, dipengaruhi usia, pendidikan, pengalaman, dan budaya. Warga pedesaan cenderung lebih akrab dengan tanaman obat karena kedekatan dengan alam dan tradisi, sementara di perkotaan mulai tergeser oleh obat modern. Untuk melindungi masyarakat dari produk ilegal atau berbahaya, BPOM menyediakan layanan Cek BPOM guna memastikan keamanan dan legalitas produk obat, makanan, kosmetik, dan suplemen. Di sisi lain, remaja rentan mengalami jerawat akibat perubahan hormonal, khususnya peningkatan hormon androgen yang memicu produksi sebum berlebih. Faktor lain yang memperparah jerawat meliputi genetik, pola hidup tidak sehat, stres, kurang menjaga kebersihan kulit, dan penggunaan kosmetik yang tidak sesuai. Edukasi dan pemilihan produk perawatan yang aman sangat penting pada fase ini. Dengan pemahaman dan penanganan yang tepat, jerawat pada remaja dapat dikontrol sehingga tidak berdampak negatif pada kesehatan fisik maupun psikologis. Hasil penelitian terjadi peningkatan pengetahuan peserta sebesar 40% tentang sosialisasi tanaman obat tradisional, 90% peserta mengaku lebih percaya diri dalam memilih produk karena memahami cara memverifikasi izin edar dan keamanan produk dan peserta menunjukkan peningkatan pengetahuan tentang kebersihan kulit, bahaya steroid tanpa pengawasan, dan pentingnya konsultasi ke tenaga Kesehatan. Kegiatan pengabdian masyarakat ini berhasil meningkatkan pengetahuan dan kesadaran masyarakat terkait pemanfaatan tanaman obat tradisional (TOGA), penggunaan layanan cekBPOM untuk memastikan keamanan produk, serta penanganan jerawat dan penyakit kulit lainnya. Edukasi terpadu yang diberikan menunjukkan peningkatan signifikan pada pemahaman peserta di seluruh aspek yang disosialisasikan, dengan antusiasme tinggi terhadap penggunaan bahan alami dan produk yang legal serta aman.
Pemanfaatan Jahe dan Pengolahannya untuk Kesehatan di SMA 1 pantai Cermin Surian Kamal, Sefrianita; Serdiani, Serdiani; Nofrizal, Nofrizal; Dwinatrana, Khiky; Azzahra, Rafifa; Anggia, Malse; Fitri, Widya; Sari, Dian Permata; Azura, Faradila; Cahyani, Dinda; Fajriani, Susi
Jurnal Pengabdian Masyarakat Dharma Andalas Vol 3 No 2 (2025): Jurnal Pengabdian Masyarakat Dharma Andalas
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jpmda.v3i2.1953

Abstract

Plants from the Zingiberaceae family are the most commonly used in traditional medicine in Indonesia. Although modern medicine is rapidly developing in Indonesia, traditional medicine is still very often used in villages and cities. The part of the plant in the family member of the Zingiberaceae that is often used is its rhizoma which is distinctively aromatic and contains evaporated oil. This ginger has a lot of benefits, especially for health. Its antioxidant content can protect the body from free radicals and cell malignancy. Information about the benefits of this ginger plant was conveyed to the State High School 1 Pantai Cermin Surian, Solok Regency. This ginger plant can also be processed into an instant drink of ginger powder, On a visit to this school, a demonstration of making instant ginger was also carried out. It is hoped that through this service, students at SMA 1 Pantai Cermin can find out the benefits and how to process ginger.
Essential Oils from Etlingera elatior Inflorescence against α-Amylase and α-Glucosidase Inhibition Syafni, Nova; Nofrizal, Nofrizal; Ismed, Friardi; Putra, Deddi Prima
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 1 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i1.812

Abstract

The increasing number of diabetes mellitus cases every year is alarming for every country. More than 90% of the cases are type-2 diabetes mellitus. The range of diabetes mellitus patients is at a productive age, including in Indonesia. Type-2 diabetes mellitus can be managed by reducing postprandial glucose levels. The approach inhibits α-amylase and α-glucosidase enzymes. A preliminary study on the local edible plants in Solok district, Etlingera elatior, showed potential against the α-glucosidase enzyme by TLC-bioautography screening. The essential oils from the inflorescence of E. elatior were extracted by hydro-distillation. The analysis of components from the essential oils identified 20 compounds. GC-MS data showed that the highest abundance percentages were 1-dodecanol (39.79%), dodecanal (28.20%), α-pinene (13.11%), decanal (4.16%), and dodecanol acetate (2.75%). The inhibition against the α-glucosidase enzyme obtains the IC50 value of 73.95 and 67.55 ?g/mL for the essential oils and acarbose, respectively. The inhibition against the α-amylase enzyme obtains the IC50 value of 70.87 and 12.28 ?g/mL for the essential oils and acarbose, respectively. The essential oils from the inflorescence of E. elatior could inhibit α-amylase and α-glucosidase enzymes, even though the potential was lower than that of acarbose as a positive control.
Inhibition of Edible Plant Torch Ginger (Etlingera elatior (Jack) R. M. Sm.) against α-Glucosidase and α-Amylase Syafni, Nova; Fakhriadi, Athallah; Nofrizal, Nofrizal; Ismed, Friardi; Putra, Deddi Prima
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.348-352.2023

Abstract

Indonesia's diabetes cases were in the top ten list globally, with 90% of the patients being type-2 diabetes mellitus (T2DM).  An approach for screening the local edible plants is made for managing or treating T2DM by inhibiting α-glucosidase and α-amylase enzymes. Results showed that inflorescence of Etlingera elatior inhibition toward both enzymes. TLC-autography and IC50 value of fractions from E. elatior were used to identify the potential fractions and possible compounds for the activity. The non-polar fraction was spotted in the active substances based on TLC-autography. Then, the targeted compounds were separated by column chromatography to obtain stigmasterol as one of the active compounds. The IC50 values of total extract, n-hexane, EtOAc, BuOH, and isolated compound against α-glucosidase were 16.0, 7.5, 13.5, 9.7, and 2.0 ppm, respectively. The IC50 values for α-amylase inhibition were respectively 88.6, 48.6, 23.2, 29.1, and 27.5 ppm. The positive control (acarbose) against α-glucosidase and amylase exhibited IC50 values of 153.2 and 12.3 ppm. The inhibition of E. elatior against the two enzymes could be an alternative to delay carbohydrate absorption.
Effect Of Postharvest Drying Methods On Total Flavonoid Content, Total Phenolic Content, Antioxidant Activity, And Sensory Acceptance Of Coffee Mistletoe (Scurrula ferruginea [Roxb. Ex Jack] Danser) Tea Nofrizal; Astarie, Shinta Angelia; Putri, Lusia Eka
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 5 No. 1 (2026): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v5i1.238

Abstract

Postharvest drying is a critical step in herbal tea processing as it affects the quality of simplicia, phytochemical content, biological activity, and sensory characteristics of the product. This study aimed to evaluate the effect of postharvest drying methods on total flavonoid content, total phenolic content, antioxidant activity, and sensory acceptance of coffee mistletoe (Scurrula ferruginea [Roxb. ex Jack] Danser) leaf tea. Coffee mistletoe leaves were dried using three different methods: sun drying, oven drying at 40°C, and room-temperature air drying. The dried samples were characterized physicochemically and analyzed for total flavonoid content (AlCl₃ method), total phenolic content (Folin–Ciocalteu method), and antioxidant activity using the DPPH radical scavenging assay (IC₅₀). A sensory acceptance test involving 20 panelists was conducted to evaluate aroma, color, and taste of the tea infusion. The results showed that the drying method significantly affected all evaluated parameters (p < 0.05). Sun drying produced the highest total flavonoid content (2.15 mmol QE/100g sample) and the highest sensory acceptance. Room-temperature drying resulted in the highest total phenolic content (51.41 mmol GAE/100g sample) and the strongest antioxidant activity with the lowest IC₅₀ value (86.4 µg/mL). Oven drying was the most effective in reducing moisture content but led to the greatest losses in flavonoids, phenolics, antioxidant activity, and sensory quality. In conclusion, room-temperature drying is more suitable for maximizing antioxidant potential, whereas sun drying is preferable for producing herbal tea with better consumer acceptance.
Co-Authors Afriyani Amri Bakhtiar Astarie, Shinta Angelia Azura, Faradila Azzahra, Rafifa Cahyani, Dinda DAYAR ARBAIN Deddi Prima Putra Dian Permata Sari Dwinatrana, Khiky Fajriani, Susi Fakhriadi, Athallah Faroliu, Goldha Fauzan, Adrul Fitri, Widya Friardi Ismed Helmice Afriyeni Ilhami, Restu Wahyudi Kamal, Sefrianita Laras Alhabil Lusia Eka Putri M. Rifqi Efendi Malse Anggia Mesa Sukmadani Rusdi Nanda Putra Nandayasa, Wira Wahyudi Nova Syafni Nurunnisa Aprilya Yulfi Putri, Lusia Eka Rafifah Azzahra Rahmat, Albiya Rosiana Rizal Rustini Rustini Sara Surya Sara Surya Sefrianita Kamal Serdiani, Serdiani Surya, Sara Usman, Hendrizal Wahyu, Yazid Zidani Widia Rahma Putri Yesi Elsandra