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PEMANFAATAN LIMBAH SAMPAH RUMAH TANGGA SEBAGAI KOMPOS Risa Supriningrum; Hayatus Sa'adah; Henny Nurhasnawati
Jurnal Abdi Masyarakat Kita Vol 1 No 2 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1197.704 KB) | DOI: 10.33759/asta.v1i2.163

Abstract

Garbage is a problem that has not been resolved until now. The central and local governments have tried to make regulations on waste management and have disseminated them to the public, but the waste problem still cannot be resolved. Community concern for the environment plays an important role in overcoming this problem. Starting from the smallest scope, namely the family or household to get used to managing waste properly and correctly. Household waste, especially kitchen waste, can be used as compost. The processing of household waste into compost can be done individually or in groups such as at the RT level. This community service aims to provide counseling about the importance of maintaining environmental cleanliness and the use of household kitchen waste as compost. The activity is intended for residents of Jalan Agus Salim RT 18, Sungai Pinang Luar District, Samarinda. The method used is counseling followed by demonstration of composting, pre-test and post-test are also carried out to determine the level of community understanding of this community service activity. This activity was attended by the head of the RT and several residents as representatives of the residents of the RT. The existence of this activity is expected to change people's behavior to be better in managing waste and become a source of income for residents.
Edukasi Dagusibu Antibiotik Bagi Masyarakat Kelurahan Sambutan Samarinda Risa Supriningrum; Ghina Adhilla; Dwi Ajeng
Jurnal Abdi Masyarakat Kita Vol 3 No 2 (2023): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/asta.v3i2.407

Abstract

Efforts to increase public knowledge and understanding about the use of antibiotics need to be made. This is because many people assume that antibiotic drugs are drugs to cure various diseases. This growing phenomenon among the community is motivated by the lack of knowledge related to the use of antibiotics. Education on Dagusibu (Get, Use, Store and Dispose) antibiotics is expected to increase people's understanding of how to get, use, store and dispose of antibiotics and can implement it in everyday life, especially in the immediate family environment. This community service activity by lecturers of the College of Health Sciences was carried out in Sambutan Village, Sambutan District, Samarinda, East Kalimantan. The counseling participants were PKK mothers and Posyandu cadres who were expected to disseminate the information we had conveyed to the surrounding community. Keywords: Dagusibu, antibiotics, Sambutan Village
Karakterisasi Ekstrak Etanol Daun Selutui Puka Tabernaemontana macrocarpa Jack. Asmi Risyah Ekawati; Risa Supriningrum; Fitri Handayani
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 20, No 1 (2023): Jurnal Ilmu Farmasi & Farmasi Klinik
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v20i1.8058

Abstract

Selutui puka (Tabernaemontana macrocarpa Jack.) secara empiris digunakan oleh Suku Dayak sebagai obat sakit gigi dan sariawan. Getahnya digunakan sebagai pengobatan tumor, kudis dan kulit melepuh. Selutui puka berpotensi untuk dikembangkan menjadi obat tradisional, sehingga perlu dilakukan karakterisasi.  Tujuan penelitian adalah untuk mengetahui karakteristik spesifik dan non spesifik ekstrak etanol daun selutui puka (EEDSP). Daun selutui puka diekstraksi secara maserasi dengan etanol 70%. EEDSP dikarakterisasi meliputi parameter spesifik yaitu organoleptik, kadar senyawa larut air dan etanol serta kandungan metabolit sekunder. Parameter non-spesifik meliputi kadar abu total, kadar abu tidak larut asam, cemaran mikroba dan angka kapang khamir (AKK). Hasil diperoleh rendemen ekstrak sebesar 20,76%. EEDSP berwarna hijau kehitaman, kental, rasa pahit, dan berbau khas. Kadar rata-rata senyawa terlarut dalam air dan etanol masing-masing 20± 0,00% dan 36,66±5,50%. EEDSP mengandung alkaloid, flavonoid, saponin, tanin, dan steroid. Kadar air, abu total dan abu tidak larut asam masing-masing 0,38 ± 0,01; 21,66 ± 2,08 dan 8,35 ± 0,03 . Hasil dari total cemaran mikroba sebanyak  6,1 × 10-2  koloni/g serta AKK 5,7 × 10-2 koloni/g. Seluruh parameter karakteristik EEDSP memenuhi persyaratan.
TOTAL FLAVONOID CONTENT AND ANTIOXIDANT ACTIVITY OF YELLOW PUMPKIN (Cucurbita moschata Duch) FRUIT EXTRACT Yudha Pratama; Risa Supriningrum; Supomo Supomo
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 10, No 1 (2024)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v10i1.14302

Abstract

Pumpkin (Cucurbita moschata Duch) is a food rich in vitamin A, vitamin C, minerals, carbohydrates, and flavonoid compounds. Flavonoids have several pharmacological activities, including as antioxidants to ward off free radicals. This study aims to determine the total flavonoid content and antioxidant activity of pumpkin fruit. The extraction of pumpkin fruit was done by the maceration method in a 70% ethanol solvent. The total flavonoid test used the colorimetric method with a 10% AlCl3 reagent and quercetin as a positive control. Antioxidant activity was tested using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The results obtained for the total flavonoid content of the ethanol extract of pumpkin fruit amounted to 1.741 mgQE/g ± 0.2438 and an IC50 value of 379.44 ppm, including the category of weak antioxidant, compared with the positive control.
Perbandingan Efek Antihipertensi Ekstrak Etanol White Tea, Yellow Tea, Black Dragon Tea dan Green Tea Susilowati, Agustina; Qarriy ‘Aina Urfiyya; Andi Wijaya; Reksi Sundu; Risa Supriningrum
Media Farmasi Vol 20 No 1 (2024): Media Farmasi Edisi April 2024
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v20i1.236

Abstract

Comparison Of Antihypertension Effects Of White Tea, Yellow Tea, Black Dragon Tea And Green Tea Ethanol Extracts In Indonesia, hypertension is still a significant health issue. Every year, Indonesia sees a rise in the prevalence of hypertension. Green tea, black dragon tea, white tea, and yellow tea all contain flavonoid antioxidants that may be used to treat hypertension by acting through the antioxidant route. The comparison of the antihypertensive effects of various ethanol extracts of white tea, yellow tea, blackdragon tea, and premium green tea (Camellia sinensis L.) is the main goal of this study. Pretest-Posttest Control Group Design research is this kind of experimental study. White tea, yellow tea, black dragon tea, and premium green tea (Camellia sinensis L.) were all subjected to antihypertensive tests using various ethanol extracts. Thirty Wistar rats were placed into six groups for the antihypertension test, each group comprising are group I (CMC. Na 1%), Group II (Captopril 2.25 mg/kgW), Groups III, IV, V and VI were the treatment groups. which consists of administering ethanol extracts of White Tea, Yellow Tea, Black Dragon Tea and Green Tea Premium at a dose of 500 mg/kgW. Blood pressure checks were carried out 3 times, namely before induction (TD I), after induction (TD II), and after being given the test solution (TD III). The results of the blood measurements then calculate the antihypertensive activity. In this study, it was discovered that captopril had a 40.0% antihypertensive action, compared to 33.3% for white tea ethanol extract, 37.2% for yellow tea, 37.7% for black dragon tea, and 38.0% for green tea. The results of this study indicate that the four ethanol extracts of tea, when administered at a dose of 500 mg/kgBB, can have an antihypertensive effect. However, only yellow tea, black dragon tea, and green tea are not substantially different from captopril (p>0.05).  Hipertensi masih menjadi suatu masalah kesehatan yang cukup besar di Indonesia. Prevalensi hipertensi di Indonesia terus meningkat setiap tahunnya. White tea, yellow tea, black dragon tea dan green tea mengandung senyawa flavonoid sebagai antioksidan yang dapat berpotensi sebagai antihipertensi dengan melalui jalur antioksidan. Tujuan dari penelitian ini yaitu mengetahui perbandingan efek antihipertensi berbagai ekstrak etanol white tea, yellow tea, blackdragon tea dan green tea premium (Camellia sinensis L.). Jenis penelitian ini yaitu penelitian eksperimental Pretest-Posttest Control Group Design. Uji antihipertensi berbagai ekstrak etanol berbagai produk teh yaitu white tea, yellow tea, black dragon tea dan green tea premium (Camellia sinensis L.). Pada uji antihipertensi, 30 ekor tikus galur wistar di bagi menjadi 6 kelompok yang terdiri dari kelompok I (CMC. Na 1%), Kelompok II (Captopril 2,25 mg/kgBB), Kelompok III, IV, V dan VI merupakan kelompok perlakuan yang terdiri dari pemberian ekstrak etanol White Tea, Yellow Tea, Black Dragon Tea dan Green Tea Premium dengan dosis 500 mg/kgBB. Pengecekan tekanan darah dilakukan sebanyak 3 kali yaitu pada sebelum penginduksian (TD I), setelah penginduksian (TD II), dan setelah diberikan larutan uji (TD III). Hasil Pengukuran darah tersebut kemudian dihitung aktivitas antihipertensinya. Pada penelitian ini dapat diperoleh data bahwa aktivitas antihipertensi Captopril 40,0%, ekstrak etanol white tea 33,3%, yellow tea 37,2%, black dragon tea 37,7% dan green tea 38,0%. Melalui penelitian ini dapat disimpulkan bahwa keempat ekstrak etanol teh tersebut dengan dosis 500mg/kgBB dapat berefek sebagai antihipertensi, namun hanya yellow tea, black dragon tea dan green tea yang tidak berbeda bermakna (p>0,05) dibandingkan dengan captopril.
Penetapan Kadar Flavonoid Total Ekstrak Etanol Kulit Buah Labu Kuning (Cucurbita moschata) Berdasarkan Perbedaan Konsentrasi Pelarut Secara Spektrofotometri UV-Vis ilham, ilham; Supriningrum, Risa; Warnida, Husnul
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 25, No 1 (2024): CHEMICA
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemica.v25i1.59074

Abstract

ABSTRAKKulit labu kuning ( Cucurbita moschata ) yang selama ini dianggap sebagai limbah ternyata memiliki manfaat antara lain sebagai antibakteri, antioksidan, karena senyawa metabolit sekunder yang dikandungnya. Salah satu senyawa metabolit sekundernya adalah flavonoid. Penyarian senyawa aktif dalam bahan alam dapat dipengaruhi oleh konsentrasi pelarut. Tujuan penelitian ini adalah mengetahui kadar flavonoid total ekstrak etanol kulit buah labu kuning berdasarkan perbedaan konsentrasi pelarut etanol. Tahapan penelitian meliputi penentuan tanaman, pengumpulan bahan baku, pembuatan simplisia, penetapan kadar flavonoid total secara spektrofotometri UV-Vis. Variabel bebas pada penelitian ini adalah variasi konsentrasi etanol 70% dan 95%, variabel ikatan berupa kadar flavonoid total, variabel kontrol berupa metode ekstraksi, tempat pengambilan sampel. Analisis data yang digunakan adalah analisis deskriptif. Hasil penelitian menyatakan persen rendemen ekstrak etanol 70% dan 95%, masing-masing adalah 13,68% dan 15,54%. Kadar flavonoid total dari ekstrak etanol 70% dan 95%, masing-masing sebesar 1,1931% ± 0,0810; dan 1,2045% ± 0,0854. Sehingga dapat disimpulkan bahwa konsentrasi pelarut etanol berpengaruh terhadap kadar rendemen dan ekstrak flavonoid kulit buah labu kuning.Kata kunci : Cucurbita moschata , flavonoid, konsentrasi pelarut, spektrofotometri UV-Vis. ABSTRACTThe skin of pumpkin (Cucurbita moschata) which has been considered as waste so far has benefits such as antibacterial, and antioxidant, because of the secondary metabolites it contains. One of the secondary metabolites is flavonoids. The Extraction of active compounds in natural products can be affected by solvent concentration. The purpose of this study was to determine the total flavonoid content of the ethanol extract of pumpkin peel based on differences in ethanol solvent concentration. The stages of the research included plant determination, raw material collection, simplicia manufacture, extraction by maceration with variations in ethanol concentration, flavonoid phytochemical screening, and determination of total flavonoid content by UV-Vis spectrophotometry. The independent variable in this study was the variation of 70% and 95% ethanol concentration, the dependent variable was the total flavonoid content, and control variable was the extraction method, where the sample was taken. The data analysis used is descriptive analysis. The results of the study stated that the percent yield of 70% and 95% ethanol extract were 13.68% and 15.54%, respectively. The total flavonoid content of 70% and 95% ethanol extract, respectively, were 1.1931% ± 0.0810, 1.2045% ± 0.0854. So it can be concluded that the concentration of ethanol solvent affects the yield and flavonoid levels of pumpkin peel extract.Keywords : Cucurbita moschata, flavonoids, solvent concentration, UV-Vis spectrophotometry.
TOTAL FLAVONOID CONTENT OF KAPUL FRUIT PEEL EXTRACT (Baccaurea macrocarpa) BASED ON SOLVENT TYPE VARIATION USING UV-VIS SPECTROPHOTOMETRY Rahmadani, Rahmadani; Supriningrum, Risa; Sa'adah, Hayatus
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 10, No 3 (2024)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v10i3.16642

Abstract

The solvent type plays a crucial role in influencing the extraction of active compounds from natural materials. The peel of kapul fruit (Baccaurea macrocarpa) is known to contain flavonoid compounds with notable antibacterial properties. This study aimed to quantify the total flavonoid content in kapul fruit peel extract by evaluating the effects of different solvent types using the UV-Vis spectrophotometric method. The analysis revealed the presence of secondary metabolites, including alkaloids, saponins, and flavonoids. The total flavonoid content of the kapul fruit peel extract varied significantly across different solvents: 4.7238 ± 0.5807 mgQE/g for ethanol, 2.9699 ± 0.1539 mgQE/g for ethyl acetate, and 2.0417 ± 0.4236 mgQE/g for n-hexane. Statistical analysis demonstrated a significant difference in flavonoid content among the three solvent extracts. These results highlight the importance of solvent selection in maximizing the extraction efficiency of flavonoids from kapul fruit peel, which may have implications for its potential therapeutic applications.
UJI PENDAHULUAN DAUN TENEM Litsea cubeba (Lour.) Pers Risa Supriningrum; Medi Hendra; Hendri Misak
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i1.42

Abstract

Litsea cubeba (Lour Pers.) has been used by the Dayak community Lundayeh and Kenyah, the village of Long Berang, District Mentarang, North Borneo, as drug . Leaves and bark used as medicine for diarrhea. Preliminary data concerning the characteristics and content of secondary metabolites has not been reported. This study aims to determine the organoleptic, macroscopic,  microscopic characteristics and content of secondary metabolites tenem leaves. The results showed that the leaf tenem have organoleptic characteristics typical aromatic smell like citrus (lemon), taste slightly bitter, slightly spicy, chelates. Macroscopic characteristics in the form of a single leaf, lanceolate, elongated, tapered leaf tip, leaf base tapering, bone pinnate leaves, upper surface shiny, lower surface dull and slightly hairy, color light green to dark green. Microscopy test results showed fragments of sklereid, oil cell, stomata type of parasitic, non-glandular trichomes. Simplicia tenem leaf powder contains alkaloids, tannins and terpenoids. The ethanol extract of leaves tenem containing compounds, terpenoids, tannins, alkaloids
UJI TOKSISITAS AKUT EKSTRAK ETANOL AKAR KB (Coptosapelta tomentosa Valeton ex K.Heyne) DENGAN METODE Brine Shrimp Lethality Test (BSLT) Risa Supriningrum; Sapri Sapri; Vici Ali Pranamala
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i2.61

Abstract

The roots of KB plants (Captosapelta tomentisa) is used empiricallyby  Dayak Kenyah community as a drug leukorrhea. Leukorrhea is one of the early symptoms of cervical cancer. Early methods to determine the LC50 value or toxicity of anticancer KB roots have not been reported. The aim of research is to determine the value of the toxicity of KB root. Research was conducted by an experimental study. Research stages include sample processing, extraction and acute toxicity test by Brine Shrimp Lethality Test (BSLT). BSLT testing to determine LC50 values with a concentration of 250 ppm, 300 ppm, 400 ppm, 450 ppm and a negative control. Analysis of the data used are probit analysis method. The results showed  the presence of flavonoids, alkaloids and saponins in of the ethanol extract of KB root . The test results obtained acute toxicity LC50 value is 299.226 mg / ml, so that the ethanol extract of roots KB potentially toxic to the larvae of Artemia salina Leach.
PENETAPAN KADAR FLAVONOID EKSTRAK ETANOL DAUN PACAR KUKU (Lawsonia inermis L.) BERDASARKAN PERBEDAAN CARA PENGERINGAN Risa Supriningrum; Nurul Fatimah; Sri Nur Wahyuni
Jurnal Ilmiah Manuntung Vol 4 No 2 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i2.195

Abstract

Leaves of Lawsonia inermis L. are one of the medicinal plants that have antibacterial properties, medicine for wounds on the skin, drugs for inflammation of the knuckles and as a nail dye. One of the active substances contained in the henna leaf is flavonoids. The level of active ingredient extract can be influenced by the way of drying simplicia. The purpose of this study was to determine the levels of flavonoid ethanol extract of girlfriend nail Lawsonia inermis L. leaves based on simplicia drying method. Research conducted was non-experimental research. The stages of the study included collecting samples, determining plants, making simplicia by drying the wind and artificial drying with an oven at 550C, extracting by maceration and determining flavonoid levels by UV-Vis spectrophotometry. The data obtained were analyzed descriptively. Based on the results of the study, obtained flavonoid levels of ethanol extract of leaves on wind-dried drying of 6.15% ± 0.1373 and drying with an oven of 7.37% ± 0.2158.