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All Journal Jurnal Pendidikan Biologi Undiksha Jurnal Natur Indonesia Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Medula Bulletin of Electrical Engineering and Informatics Biogenesis: Jurnal Ilmiah Biologi JURNAL BIOLOGI INDONESIA Jurnal Biologi Tropis Jurdimas (Jurnal Pengabdian Kepada Masyarakat) Royal JURNAL PENELITIAN PERAWAT PROFESIONAL Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Kedokteran Hewan JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Sutyarso Sutyarso
Bagian Patologi Anatomi Fakultas Kedokteran Universitas Lampung, jalan Soemantri Brojonegoro 1 Bandar Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Medula

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ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN DISFUNGSI EREKSI PADA PASIEN BENIGN PROSTAT HIPERPLASIA DI RS YUKUM MEDICAL CENTRE Kamalia, Avissa Medina; Hadibrata, Exsa; Susianti, Susianti; Sutyarso, Sutyarso
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1116

Abstract

Benign Prostate Hyperplasia (BPH) is the second most common urology’s disease in Indonesia. This disease occurs due to hyperplasia of stromal cells and epithelial cells of the prostate. The clinical manifestations of this disease consist of obstruction symptoms, irritation symptoms, and post void symptoms. People with BPH often complain about the decrease of their quality of life. One of the factor that Impaired to their quality of life is erectile dysfunction. This study aims to identify the factors that impact the incidence of erectile dysfunction in BPH patients at Yukum Medical Centre Hospital. There were 67 men with bph was obtained from Yukum Medical Centre Hospital in January-September 2021. Data were collected with International Index of Erectile Function-5 questionnaire and medical records. Data were analysis with chi-square test using SPSS and a p-value (<0,05 was considered significant). The result showed that 39 BPH patients had erectile dysfunction. Mean age of BPH patiens with erectile dysfunction was 66,74 (SD±6,51) and mean IIEF-5 scores of the BPH patients was 19,41 (SD±4,23). Age and prostate volume had significant impact with p-value 0,004 and 0,002 respectively. Treatment and medication didn’t have significant impact with p-value 0,193, and 0,856 respectively. Age and prostate volume have a significant impact on the incidence of erectile dysfunction in BPH patients. However, treatment and the type of medication doesn’t impact the risk of incident erectile dysfunction in BPH patients.
Phosphatidylserine Exposure in Thalassemia Β Patients Sangging, Putu Ristyaning Ayu; Sutyarso, Sutyarso; Busman, Hendri
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1162

Abstract

Thalassemia is a genetic disorder that involves the formation of abnormal hemoglobin. Thalassemia is divided into two main categories namely alpha and beta thalassemia depending on the hemoglobin chain affected. Although some categories of thalassemia are mild and cause only mild anemia and iron deficiency problems in patients, other, more severe forms of thalassemia can result in death. Thalassemia sufferers can get treatment according to the severity of the condition. The degree of ineffective erythropoiesis is known to be associated with clinical severity in individuals with thalassemia. However, the association of ineffective erythropoiesis biomarker levels with different thalassemia genotypes is limited. Studies have explored levels of red blood cells exposed to phosphatidylserine and ineffective erythropoiesis biomarkers in patients with different genotypes. Based on the results of the review, beta thalassemia patients have the highest GDF-15 levels, followed by patients with non-deletal alpha thalassemia. Patients with non-delesional alpha thalassemia showed elevated hemoglobin levels and decreased GDF-15 levels after splenectomy. Patients with beta thalassemia and non-delesional alpha thalassemia had the highest levels of red blood cell exposure to PS and ineffective erythropoiesis biomarkers, which correlated with the clinical severity of thalassemia. Differences in erythropoiesis rates are not effective in thalassemia, which emphasizes the need for different treatment approaches in patients with different thalassemia genotypes.
Co-Authors Abdullah Setiawan, Wawan Akmal Junaidi Ardiansyah, Budi Khoiri Ayu S, Putu Ristyaning Azizah, Enur Betta Kurniawan, Betta Damayanti Damayanti Dewi Nur Fiana Elidiya, Anggun Endah Setyaningrum, Endah Endang Nurcahyani Ernawiati, Eti Hadibrata, Exsa Halimi, Sofwan Hanna Mutiara, Hanna Hendri Busman Hidayat Hidayat Indriyani Indriyani J. Supriatna Jhons Fatriyadi Suwandi Kamalia, Avissa Medina Kanedi, Mohammad - Kurniawaty, Evi Madi Hartono Muhartono Muhartono Mumtazah, Dzul Fithria N. Moeloek N. Suhana Nirwana Hendrastuty Nugroho Susanto, Gregorius Nuning Nurcahyani O. Soeradi Oktafany, Oktafany Puspitaningsih N.W., Rr. Etty Radella Hervidea, Radella Ratna Dewi Puspita Sari Rosa, Emantis Rosyking Lumbanraja, Favorisen S. S. Sukmaniah Safitri, Dewi Restika Ayu Sangging, Putu Ristyaning Ayu Sarasati, Filia Sumardi . Susanto, G. Nugroho Susanto, G. Nugroho Susanto, Gregorius Nugroho Susianti Susianti Susianti, Susianti Sussi Astuti Sutarto Sutarto Syazili Mustofa Tintin Kurtini Tri Umiana Soleha Widiastuti, Endang Linirin Widiastuti, Endang Linirin Winda Trijayanthi Utama, Winda Trijayanthi