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All Journal Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Jurnal Bakti Saraswati Journal of Indonesian Dental Association Interdental Jurnal Kedokteran Gigi (IJKG) MDJ (Makassar Dental Journal) Jurnal Ilmiah Medicamento International Journal of Applied Science and Sustainable Development (IJASSD) Odonto dental journal
Dewa Made Wedagama
Faculty Of Dentistry, Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Education Engineering Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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Perkembangan Tren Terapi Pulpa Vital melalui Aplikasi berbagai Biomaterial: Penelitian Bibliometrik Widyastuti, Wiena; Anggraini, Wita; Fibryanto, Eko; Roeslan, Moehamad Orliando; Gunardi, Indrayadi; Rizal, Muhammad Ihsan; Khazin, Sobrina Mohamed; Wedagama, Dewa Made
Jurnal Ilmiah Medicamento Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento (In progress)
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i2.11749

Abstract

Vital pulp therapy (VPT) is a crucial dental intervention designed to maintain the vitality of the dental pulp, particularly in carious lesions or trauma. The evolution of biomaterials in VPT has significantly affected dental practices by providing less invasive alternatives that safeguard tooth vitality and functionality. Continued exploration of the properties and effects of these materials is crucial for enhancing treatment strategies and optimizing dental care outcomes. Bibliometric analysis allowed the assessment of trends in the biomaterials used for VPT. Data mining was performed using the Scopus database and Boolean expressions. Data extraction and analysis were conducted using VOSviewer version 1.6.20., VOSviewer thesaurus, and Microsoft Excel. A total of 856 documents were identified, and the United States had the largest number of documents and citations (110 documents, 6,938 citations). The top three sources were the Journal of Endodontics, International Journal of Endodontics, and Dental Materials Journal. Mineral trioxide aggregate (MTA) is still the dominant biomaterial used in VPT to this day. MTA can accelerate dentinogenesis in VPT. The prominence of “MTA” and “VPT” as keywords highlights research on prevalence, causes, prevention, and evaluation, emphasizing the need to investigate biomaterial-driven healing, regeneration, stem cell activity, and gene expression.
Root Canal Irrigation NaOCl 2,5% plus Nano Chitosan as an Antibacterial Pseudomonas Aeruginosa Wedagama, Dewa Made
Journal of Indonesian Dental Association Vol 8 No 2 (2025): October
Publisher : Indonesian Dental Association

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Abstract

Chitosan tilapia scales is one of the chitosans which has benefits as an antibacterial in dental root canal, the physical size of chitosan can be converted into smaller particle sizes in the form of nanoparticles. For the material of root canal irrigation as a gold standard is sodium hypochlorite 0.5% -5.25%. One of the bacteria found in the root canal is Pseudomonas aeruginosa. The purpose of this study was to determine the effectiveness of nano chitosan tilapia scales plus 1.5% and 2.5% NaOCl in inhibiting Pseudomonas aeruginosa. This research is a laboratory experimental study with the research design used is the Post Test Only Control Group Design antibacterial test Kirby Bauer. The sample used was the bacterium Pseudomonas aeruginosa which was divided into 4 groups: group 1 was the treatment group given nano chitosan of tilapia scales plus 1.5% NaOCl, group 2 was the treatment group given nano chitosan of tilapia scales plus 2.5% NaOCl, group 3 of the treatment group was given a positive control with Chlorhexidine and group 4 of the treatment group was given a negative control of aquadest with 6 repetitions for each. The results of statistical tests using the Least Significant Difference (LSD) test showed that there were significant differences in the inhibition zone between nano chitosan of tilapia scale plus 1.5% and 2.5% NaOCl with a value of r <0.05. The average inhibition power of nano chitosan of tilapia scales plus 1.5% NaOCl was 21.33 mm and nano chitosan of tilapia scales plus 2.5% NaOCl was 24.83. It can be concluded that nano chitosan of tilapia scale plus 1.5% NaOCl and nano chitosan of tilapia scale plus 2.5% NaOCl have very strong inhibition against Pseudomonas aeruginosa. Nano chitosan of tilapia scales plus 2.5% NaOCl is more effective in inhibiting Pseudomonas aeruginosa. Keywords: Root canal irrigation NaOCl 2.5%, Nano Chitosan, Antibacterial
Co-Authors A.A.A. Hartini Agung, I Gusti Ayu Ari Atia Nurul Sidiqa Atia Nurul Sidiqa Dewi Farida Nurlitasari Dewi, Ni Pt Okta Kristia Dwis Syahriel Ernawati, Kadek Lusi Fibryanto, Eko G.A.A. Hartini Gusti Ayu Yohanna Lily Halim, Willy Hadinata Haris Nasutianto Hartini, I G A A Haryo Mustiko Dipoyono Hervina I Gusti Ayu Agung Hartini I Gusti Ayu Ari Agung I Gusti Ayu Dewi Haryani I Nyoman Panji Triadnya Palgunadi Ida Ayu Siwi Gayatri Ilma Yudistian Indrayadi Gunardi, Indrayadi Julita Hendrartini Khazin, Sobrina Mohamed Muhammad Ihsan Rizal, Muhammad Ihsan Ni Pt Okta Kristia Dewi Ni Putu Idaryati Ni Putu Widani Astuti P Rusmiany Ratih Widyasari Ratih Widyasari, Ratih Ria Koesoemawati Roeslan, Moehamad Orliando Widowati Siswomihardjo Widyastuti, Wiena Willy Hadinata Halim Wita Anggraini Yayi Suryo Prabandari