Article Per Year (5 Year)
p-Index From 2021 - 2026
2.064
P-Index
This Author published in this journals
All Journal JOPS (Journal Of Pharmacy and Science) Ensiklopedia of Journal Human Care Journal JPK: Jurnal Proteksi Kesehatan Riset Informasi Kesehatan Journal of Pharmaceutical and Sciences.
Miming Andika
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
A Test of the effectiveness of the ethyl acetate fraction of dayak onion bulbs (eleutherine bulbosa (mill.) urb) as an antihypertensive Sari, Putri Nilam; Andika, Miming; Hasnita, Evi; Hasanah, Rizqa; Fitriani, Oriza Sativa; Putra, Fajrian Aulia; Rahmadasmi, Nola; Nanda, Nanda; Handayani, Tuti
Riset Informasi Kesehatan Vol 13 No 1 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i1.836

Abstract

Hypertension is a condition where blood pressure exceeds normal limits, where systolic blood pressure is above 140 mmHg and diastolic blood pressure is above 90 mmHg. One plant that can lower blood pressure is Dayak onion bulbs. The aim of this study was to determine the effectiveness of the ethyl acetate fraction of Dayak onion bulbs (Eleutherine bulbosa (Mill) Urb) in reducing blood pressure in hypertensive male white rats. The method was experimental, using 36 male white rats, divided into 6 groups, namely negative control, positive control, dose group (50, 100, 200 mg/kgbb) and comparison group (catopril). The inducer used was 8% NaCl for 14 days. Blood pressure measurements are carried out using a Non-Invasive Blood Pressure (NIBP) device. Data analysis used One Way Anova and continued with the Duncan test. The results showed that administration of Dayak onion bulb ethyl acetate fraction had an effect on reducing systolic, diastolic, mean arterial blood pressure and heart rate significantly (p<0.05). The conclusion shows that the effective dose in reducing blood pressure is administration of the ethyl acetate fraction at a dose of 200 mg/kgbb. There was a histopathological improvement in the thickness of the left ventricular muscle in mice.
Co-Authors .AH, Ahdi Dinil Haq A, Meridha Mutiara Aini, Latyfa’ Arifa, Nurwahidatul Billy Harnaldo Putra, Dini Fatmi, Charissa Novita Dwi Setiawan Evi Hasnita Fahira Azlaini Burma Fatma Sri Wahyuni Fauzia, Haliza Diny Febriana, Tita Adhaha Ferdian, Arif Fitriani , Oryza Sativa Fitriani, Oriza Sativa Fitriani, Oryza Sativa Haq. AH, Ahdi Dinil Harry Ade Saputra Harry Ade Saputra Khaidir, Muhammad Kirani , Zabilla liana, nana Nanda , Nanda Nanda Nanda Nurdina Putri Oryza Sativa Fitriani Prima Astuti Handayani Putra, Fajrian Aulia Putri Nilam Sari Rahmadasmi, Nola Rizqa Hasanah Setiawati, Erdanela Shantrya Dhelly Susanty Vilma Humaira Wulandari , Desti Wulandari, Desti Yahdian Rasyadi Yelly Oktavia Sari Yesika, Relin Yulia Yesti Yulia Yesti, Yulia