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All Journal Medical Journal of Indonesia ASEAN Journal of Community Engagement JOURNAL LA MEDIHEALTICO Journal of General Procedural Dermatology and Venereology Indonesia
Sandra Widaty
Faculty of Medicine University of Indonesia/ Cipto Mangunkusumo Hospital, Jakarta
Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Systemic antibiotic selection in skin and soft tissue infections Purnawan, Shafira Anindya; Budianti, Windy Keumala; Widaty, Sandra
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

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Background: Antibiotics are used in daily practice. To properly select antibiotics, it is important to pay attention to the definitive diagnosis, class of antibiotic, dose, interval, route of administration, and exact duration of use. Discussion: The World Health Organization (WHO) categorizes antibiotics into three groups: Access, Watch, and Reserve—known as the AWaRe classification—to help guide appropriate usage and combat antibiotic resistance. The Gyssens flowchart serves as a valuable tool for clinicians to qualitatively evaluate antibiotic utilization. In skin and soft tissue infections (SSTIs), treatment strategies are tailored according to the characteristics of the infection, including purulence, necrosis, and overall severity. For mild-to-moderate non-purulent SSTIs, beta-lactam antibiotics, such as penicillin and cephalosporin, alongside lincosamides like clindamycin, are recommended as first-line therapies. In cases of moderate-to-severe non-purulent SSTIs, empirical therapy must account for methicillin-resistant Staphylococcus aureus (MRSA). Meanwhile, purulent SSTIs require an initial incision and drainage, with subsequent treatment options including topical antibiotics for mild cases and systemic antibiotics for more complicated or severe infections. Extensive purulent SSTI in adults is empirically considered MRSA. Conclusion: Control of antimicrobial resistance can be achieved by using antibiotics according to the AWaRe classification and evaluating the use of antibiotics qualitatively using the Gyssens flowchart.
Control of Scabies in a Boarding School Using 5% Permethrin Applied on Lesion Only Sungkar, Saleha; Wahdini, Sri; Kekalih, Aria; Rilanda, Risa; Angkasa, Hansen; Widaty, Sandra
ASEAN Journal of Community Engagement Vol. 6, No. 1
Publisher : UI Scholars Hub

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Scabies is one of the most neglected tropical skin diseases in Indonesia. It is usually found in overcrowded communities with poor hygiene. The gold standard for scabies treatment is the whole-body topical application of 5% permethrin cream. However, the treatment causes inconvenience and stickiness for a prolonged period. The modification of topical treatment by applying only to the lesion yielded results similar with whole-body topical application. We consider using this mode of treatment to control the disease in a boarding school. The study was conducted from June to August 2019. All students were examined by dermatologists, and individuals who were diagnosed with scabies were treated using 5% permethrin for 12 h before wash-off (week 0) applied on the lesion only and reapplied a week after. The evaluation was conducted on weeks 4 and 8 by observing scabies lesions. Local health cadres were also trained, and environmental interventions were also performed. A total of 75 participants were analyzed. Most lesions were found on predilection sites such as finger web spaces of the left (57.3%) and right (58.7%) hands, gluteal region (60%), and penis (40%). The cure rate (CR) was 83%–100% of the lesions in week 4, which increased to 95%–100% in week 8. The CR on week 8 compared with baseline was 94.7% (p < 0.001). A total of 23 cadres were trained, and from post-test, 84% of the cadres showed good knowledge of scabies management. This novel application of 5% permethrin cream on the lesion only is an effective alternative to the conventional whole-body topical application.
Co-Authors Anna Rozaliyani Aria Kekalih Bianti, Marsha Cornain, Emilina Faradila Darmawan, Irene Dewi Friska Githa Rahmayunita Hanny Nilasari Hansen Angkasa Hartanto, David Dwiadiputra Herwinda Brahmanti Islami, Artini Wijayanti Kartika, Emiliana Krisanti, Roro Inge Ade Kusmarinah Bramono Lili Legiawati Lim, Henry W M. Yulianto Listiawan Marissa, Melani Melinda, Thong Felicia Menaldi, Sri Linuwih Susetyo Wardhani Miranda, Eliza Mustika, Rita Nuary, Teffy Nugraheni Pasaribu, Uly Aanda Maria Oktarina, Caroline Oktavia, Nikken Rima Pandelaki, Paulus Anung Anindita Pandjaitan-Sirait, Sondang MHA Purnawan, Shafira Anindya Rahadi Rihatmadja Rilanda, Risa Rizky, Luddwi Achmad Robiatul Adawiyah Saleha Sungkar Sari, Siti Maulidya Shannaz Nadia Yusharyahya Sirait, Sondang Pandjaitan Situmeang, Irhen Sri L. Menaldi Sri Wahdini Sujudi, Yufanti Surachmiati Suseno, Lis Tugiran, Mulyati Wati, Huda Marlina Windy Keumala Budianti Yahya, Sammy Yosi, Ariyati