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All Journal Jurnal AGROTEKNOLOGI Jurnal Kedokteran Brawijaya Journal of Innovation and Applied Technology Research Journal of Life Science Jurnal Pangan dan Agroindustri Jurnal Teknologi Pertanian Indonesian Journal of Human Nutrition agriTECH Biology, Medicine, & Natural Product Chemistry Industria: Jurnal Teknologi dan Manajemen Agroindustri Amerta Nutrition Food Science and Technology Journal (Foodscitech) Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering (AFSSAAE) Nusantara Science and Technology Proceedings Jurnal Teknologi Pangan

Tri Dewanti Widyaningsih

Universitas Brawijaya

Author-ID : 416504

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Other

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EFEK HIPOGLIKEMIK EKSTRAK CINCAU HITAM (MESONA PALUSTRIS BL) PADA TIKUS WISTAR DIABETES YANG DI INDUKSI ALLOXAN Widyaningsih, Tri Dewanti; Wijayanti, Novita; Handayani, Dian; Rochmawati, Nia
Jurnal Kedokteran Brawijaya Vol 28, No 3 (2015)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2015.028.03.7

Cincau hitam atau black grass jelly (Mesona palustris BL) adalah bahan minuman tradisional Indonesia yang dipercaya bermanfaat untuk kesehatan. Cincau hitam biasanya dikonsumsi dalam bentuk gel untuk es campur. Pada penelitian ini cincau hitam dibuat serbuk sehingga praktis penggunaannya. Penelitian dilakukan untuk mengetahui efek hipoglikemik serbuk ekstrak cincau hitam pada tikus Wistar diabetes karena induksi alloxan, dengan rancangan nested design (faktor perlakuan dan waktu) pada kelompok perlakuan dan menggunakan kontrol. Pengukuran dilakukan sesudah perlakuan pada semua kelompok. Terdapat 5 kelompok, kontrol negatif (tikus normal), kontrol positif (tikus diabetes), tikus diabetes perlakuan dengan obat glibenklamid, tikus diabetes perlakuan suplemen cincau hitam dosis 1 (7,2mg/200gBB) dan perlakuan dosis 2 (21,6mg/200gBB). Hasil dari penelitian ini serbuk suplemen ekstrak cincau hitam tergolong tinggi aktifitas antioksidannya (IC50=69,04±2,89ppm). Hasil penelitian menunjukkan suplemen ekstrak cincau hitam mempunyai efek hipoglikemik. Efek hipoglikemik perlakuan suplemen dosis 2 bahkan tidak berbeda dengan perlakuan obat diabetes glibenklamid. Hasil histopatologi dengan pewarnaan HE perlakuan dosis 2 selama 4 minggu menunjukkan secara signifikan dapat memperbaiki kerusakan morfologi pulau Langerhans pankreas karena induksi alloxan. Dapat disimpulkan pemberian serbuk ekstrak cincau hitam pada dosis 21,6mg/200g BB selama 4 minggu dapat memberikan efek hipoglikemik setara dengan glibenklamid, dan memperbaiki kerusakan morfologi pulau Langerhans pankreas pada tikus diabetes yang diinduksi alloxan.Kata Kunci: Efek hipoglikemik, induksi alloxan, pulau Langerhans, serbuk ekstrak cincau hitam (Mesona palustris BL), tikus Wistar diabetes

Anti Hipertensi Minuman Serbuk Instan Campuran Ekstrak Buah Delima Merah (Punica granatum Linn.) dan Ekstrak Daun Sirih Merah (Piper crocatum) pada Tikus Hipertensi Widyaningsih, Tri Dewanti; Wijayanti, Novita Wijayanti; Syafrilia, Rosita Mega
Food Science and Technology Journal (Foodscitech) Vol 1 No 2 (2018)
Publisher : Universitas Dr Soetomo

Secara empiris buah delima merah dan daun sirih merah masing-masing telah biasa digunakan sebagai terapipenyakit hipertensi. Pembuatan serbuk instan campuran ekstrakÂ buah delima merah dan ekstrak daun sirihmerah sebagai serbuk instan tentu akan lebih praktis dan awet dalam penggunaannya sebagai minumanfungsional. Tujuan penelitian ini adalah untuk menghasilkan proporsi serbuk instan campuran dari ekstrak buah delima dan ekstrak daun sirih merahÂ yang terbaik dan mengujinya sebagai antihipertensi pada tikus hipertensi yang diinduksi menggunakan NaCl 2% dan prednisone 1.5 mg/kg . Hasil penelitian menghasilkanperlakuan terbaik serbuk instan campuran ekstrak buah delima merah dan ekstrak daun sirih merah denganproporsi 4:1 dengan aktivitas antioksidan(IC50) 59.43 Âµg/mL, total fenol 984.24 mgGAE/6g serta totalflavonoid 362.46 mgQE/6g. Hasil pengujian antihipetensi terbaik pada dosis 2 (1850.01 mg/kg BB) denganpresentase penurunan tekanan darah sistolik tikus 38.31%, kadar BUN 77.55% serta kadar kreatinin 58.10%.

Anti Hipertensi Minuman Serbuk Instan Campuran Ekstrak Buah Delima Merah (Punica granatum Linn.) dan Ekstrak Daun Sirih Merah (Piper crocatum) pada Tikus Hipertensi Widyaningsih, Tri Dewanti; Wijayanti, Novita Wijayanti; Syafrilia, Rosita Mega
Food Science and Technology Journal (Foodscitech) Vol. 1 No. 2 (2018)
Publisher : Universitas Dr Soetomo

Optimasi Formula Mi Kering Berbasis Ampok Jagung Terfermentasi sebagai Makanan Tambahan bagi Ibu Hamil Jaya Mahar Maligan; Agustina Maria Dwiyanti Soeyono; Tri Dewanti Widyaningsih
Industria: Jurnal Teknologi dan Manajemen Agroindustri Vol 8, No 1 (2019)
Publisher : Department of Agro-industrial Technology, University of Brawijaya

AbstrakPenelitian ini bertujuan untuk membuat mi kering berbasis ampok jagung yang difortifikasi dengan tepung tempe dan tepung daun kelor yang dapat memenuhi kebutuhan ibu hamil. Penelitian ini dibagi menjadi 2 tahap utama yaitu optimasi formula dan analisis produk akhir. Tahap optimasi formula dimulai dengan menentukan titik maksimum substitusi dari masing-masing tepung. Pembuatan mi kering substitusi tepung daun kelor dilakukan dengan level substutisi 10% hingga 35%, sedangkan untuk tepung tempe dari 15% hingga 40%. Tahap optimasi formula dilakukan dengan bantuan piranti lunak Design Expert 7.0 dengan metode rancangan campuran D-optimal. Analisis respon akan menghasilkan model persamaan. Model untuk respon warna dan cita rasa adalah linier, zat besi dan tekstur adalah kuadratik, sedangkan model untuk respon protein dan kalsium adalah kubik. Semua model tergolong signifikan sehingga dapat memberikan prediksi hasil yang baik. Solusi formula yang paling optimal, yaitu formula mi kering dengan 17,129% tepung daun kelor dan 32,871% tepung tempe. Tahap verifikasi memberikan hasil yang mendukung prediksi formula optimal tersebut. Hasil analisis menunjukan mi kering mengandung kadar air sebesar 7,45%, kadar abu sebesar 3,4%, kadar protein sebesar 28,85%, kadar lemak sebesar 6,73%, kadar kalsium sebesar 309,61 mg/100 gram, kadar zat besi sebesar 34,05 mg/100 gram, cooking loss 2,2% dan cooking time 275 detik.Kata kunci: ampok jagung, ibu hamil, makanan tambahan, mi kering, optimasi AbstractThis study aim was to make dried noodles based on fermented corn fortified with tempeh flour and moringa leaf flour that can meet the needs of pregnant women. This research was divided into two main stages, namely formula optimization and final product analysis. The formula optimization stage begins by determining the maximum substitution point of each flour. For moringa leaf flour, it was made to make dry noodles with a substitution level of 10% to 35%, while for tempeh flour from 15% to 40%. The formula optimization stage was carried out with the help of Design Expert 7.0 software with the D-optimal mixture design method. Response analysis produced an equation model. Models for color and flavor responses are linear, iron and texture are quadratic, while models for protein and calcium responses are cubic. All models are classified as significant so that they can predict good results. The most optimal formula solution was dry noodle formula with 17.129% Moringa leaf flour and 32.871% tempeh flour. The verification phase provides results that support the optimal formula prediction. The results of the analysis showed that dried noodles contained a moisture content of 7.45%, ash content of 3.4%, protein content of 28.85%, fat content of 6.73%, calcium content of 309.61 mg/100 gram, substance content iron at 34.05 mg/100 gram, cooking loss 2.2% and cooking time 275 seconds.Keywords: dry noodles, fermented corn, optimization, pregnant women, supplementary food

Technology Of Black Cincau Liang Tea As Diversified Products In Black Cincau Gel Producer At Batu City Tri Dewanti Widyaningsih
Journal of Innovation and Applied Technology Vol 1, No 1 (2015)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Universitas Brawijaya

ABSTRACT Black cincau (Mesona palustris BL) or black grass jelly is traditional beverage ingredient that is believed has efficacious for health, but the black cincau gel in the market known asunhygienic food and has shortshelf life. Liang tea of black cincau is a kind of processed product development of black cincau. Liang tea or herbal tea made from of black cincau extracts with the addition of other herbs such as ginger, cinnamon or pandan leaves. "Sumber Murni " home industry is theproducerof blackcincaugelinBatucitywhich isinterested inproducingliang tea of black cincau in a plastic cup packaging as well as product diversification for enterprise development. Therefore, Liang tea of black cincau technology package should be a well proven technology where the technology is practical, easy to introduce. Technology which applied are: 1 ) Formulation of Liang Tea is black cincau extract : water = 60 : 40 and ginger extract added = 10 % , 2 ) The process is suitable with the flow diagram, 3 ) Engineering equipment such as semi-automatic cup sealer with tank and cookers tank for blending materials with automatic stirrer .Keywords: cookers tank with automatic stirrer,liang tea of black cincau, semi-automatic cup sealer

The Effect of Processing and Cooling Methods on Coleus tuberosus in vitro Starch Digestibility Jhauharotul Muchlisyiyah; Tri Dewanti Widyaningsih; Retno Wulansari; Hera Sisca Prasmita
agriTECH Vol 41, No 3 (2021)
Publisher : Faculty of Agricultural Technology, Universitas Gadjah Mada, Yogyakarta, Indonesia

Coleus tuberosus, also known as black potato, is one of the Indonesian local tubers consumed as a carbohydrate substituent. Therefore, this study aimed to examine the effect of processing and cooling methods on the in vitro digestibility of black potato starch. Furthermore, two factors Randomized Block Design with a 2x3 experimental design was used, which consisted of processing methods (boiling, roasting, and microwave) and cooling at room temperature and 4 °C for 24 hours with 3 repetitions. Black potato flour was compared with the raw form, by assessing some parameters, namely Resistant Starch (RS), Slowly Digestible Starch (SDS), Rapidly Digestible Starch (RDS), and Glycemic Index (GI). Also, the analysis of total starch, moisture, and color was performed, hence raw black potatoes generally have 10% resistant starch (%wb). Different treatments of cooking and cooling had a significant effect (α = 0.05) on moisture content, total starch, RS, RDS, SDS, GI, brightness (L), and yellowness (b). Black potatoes subjected to the processing method followed by cooling had lower RDS and increased RS content. Furthermore, refrigeration at 4°C for 24 hours reduced the digestibility of black potato starch more than cooling at room temperature. Contrarily, microwaved black potato cooled at room temperature showed a higher digestion rate compared to the raw counterpart. Conclusively, processing followed by cooling reduces the GI and increases the RS content of Coleus tuberosus.

EFEK ANTIDIARE MINUMAN FUNGSIONAL JELLY DRINK CINCAU HITAM (Mesona palutris BL) Tri Dewanti Widyaningsih; Rahma Maya Safitri
JURNAL AGROTEKNOLOGI Vol 8 No 01 (2014)
Publisher : Faculty of Agricultural Technology, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (414.828 KB)

In tradition Indonesian make sure that the black cincau (Mesona palustris BL) is used for traditional medicine of diarrhea. Black cincau contain bioactive compounds and soluble fibers, used as antioxidants and antibacterial ingredients. Produced functional drinks of jelly drink was a development product from black cincau. The aims of the research were to produced functional beverage jelly drink from extract of black cincau and tested its as antidiarrheal in vivo to male mice. Treatment divided into 5 groups: group I (positive control), mice ware given distilled water diarrhea, group II (control drugs), diarrhea mice were given a dose of loperamide 0.182 mg/20 g weight of mice, group III, diarrhea mice were given cincau black jelly drink dose of 80 mg/20 g weight of mice, group IV, diarrhea mice were given cincau black jelly drink dose of 160 mg / 20 g weight of mice. The results showed that the best treatment was formula 2 and result of in vivo test showed that the group of mice with cincau black jelly drink dose of 80 mg/20 g weight of mice and 160 mg/20 g weight of mice had antidiarrhea effect. These effect included of mucus or watery stool consistency/longer soft on the occurrence of diarrhea, stool consistency normal influence on the timing of the normal feces and total span of diarrhea, no significantly different (p> 0.05) with the medicines control group loperamide.Keywords: cincau black jelly drink extract (Mesona palustris BL), antidiarrheal, loperamide

INTEGRATED FOOD THERAPY PRODUCT FORMULA DARI PEKTIN KULIT PISANG AGUNG SEMERU (Musa paradisiaca Formatypica), MANGGA DAN DAUN MINT SEBAGAI ANTI-KONSTIPASI PADA TIKUS WISTAR Nike Nurlaily Fitria; Rofiqoh Fajarwati; Tri Dewanti Widyaningsih
JURNAL AGROTEKNOLOGI Vol 11 No 02 (2017)
Publisher : Faculty of Agricultural Technology, University of Jember

This research aimed to optimize the formula of effervescent powder from banana peel pectin, mango, mint and to know the effect of effervescent powder to the reduction of constipations symptom of Wistar rats. This research used Response Surface Methodology (RSM) with Central Composite experimental Design (CCD) to optimize the formula of effervescent powder and used Complete Randomized Design (CRD) method with consumption of effervescent powder treatment factor for five days. The result of this research showed that the formula of effervescent powder which had high dietary fiber degree is in the proportion of pectin powder:mango powder:mint leaves powder respectively 40%:35%:25% with verified dietary fiber degree is 30.35%. Then, in anti-constipation test shows that effervescent powder feeding with dosage 180 mg/200 g BB had real effect (α=0.05) to all parameters but it didn’t influence the number of feces. Keywords: effervescent, constipation, pectin

Extraction of Glycosaminoglycans Containing Glucosamine and Chondroitin Sulfate from Chicken Claw Cartilage Tri Dewanti Widyaningsih; Widya Dwi Rukmi; Erni Sofia; Sudarma Dita Wijayanti; Novita Wijayanti; Rika Ersalia; Nia Rochmawati; Debora Nangin
Research Journal of Life Science Vol 3, No 3 (2016)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Chicken cartilage (claw) is a waste of chicken cuts which are widely available in Indonesia. Cartilage part of chicken claw becomes a potential source of chondroitin sulfate (CS) and glucosamine (GS). This study aims to determine the most optimal extraction methods of CS and GS from cartilage of chicken claw. Various types of extraction methods used in this study are taken from the extraction by using boiling water (2 and 2.5 hours), acetic acid (7 and 17 hours), as well as proteolysis by papain (24 and 48 hours). Parameters observed include chemical characteristics of powdered cartilage of chicken claw as well as CS and GS levels in powdered cartilage of chicken claw extract. The results of this research show that the levels of CS and GS of chicken claw cartilage powder were 2.17% and 13%. Meanwhile, the highest GS level was obtained from the extraction with water treatment for 2.5 hours which was 8.1%. The treatment and duration of extraction will significantly affect the number of GS which was produced. The highest content of CS was obtained from the extraction with the enzyme treatment for 48 hours which was 2.47%. The best treatment is the extraction with water treatment for 2.5 hours which were the extracts with GS levels of 8.1% and 2.03% CS was selected through the analysis of multiple attribute.

Antihypertensive Effects of Black Cincau (Mesona palustris BL) Effervescent Powder and Malondialdehyde Concentration on Wistar Rats as a Hypertensive Model Tri Dewanti Widyaningsih; Novita Wijayanti; Dian Handayani; Guntur Prasetyo
Research Journal of Life Science Vol 3, No 2 (2016)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

This study investigated the effects of Black cincau (Mesona palustris BL) effervescent powder (BCEP) on systolic blood pressure and malondialdehyde concentration in hypertensive rats. BCEP were orally administered to hypertensive rats for 4 weeks, and antihypertensive effects were determined. Rats were given 630 mg/kg, 1.260 mg/kg and 1.890 mg/kg BCEP on dose group 1, 2, 3 respectively. These groups were compared with a negative control group, hypertensive control group and Captopril control group. These results showed that systolic blood pressure and MDA concentrations of rats dosed with BCEP were significantly different (α=0,01) to those of control rats. Rats dose third group with of 1.260 mg/kg showed the highest percentage of lowering blood pressure. The rat dose third group had highest percentage decreased in systolic blood pressure (43,97%) and in MDA concentration (68,77%).Key words : Antihypertensive; Black Cincau (Mesona palustris BL) Effervescent Powder; Malondialdehyde

Co-Authors Addiena Hidayati Addiena Hidayati, Addiena Adin Pritanggo Dhesti Adin Pritanggo Dhesti Agustina Maria Dwiyanti Soeyono Agustina Tri Endharti Annisa Ulfah Pristya Arya Ulilalbab Atika Ruri Cahyaningrum Atika Ruri Cahyaningrum, Atika Ruri Aulia Shabrina Karismawati Aulia Shabrina Karismawati Aulia Shabrina Karismawati Ayu Arditiana Ayu Arditiana Bobby Andi Septian Bobby Andi Septian Christiani Tangkeallo Christiani Tangkeallo Christine Eka Wulandari Harianto Chyntia Trivena Milala Debora Nangin Dego Yusa Ali Dian Ekasari Dian Handayani Dian Handayani Dian Kasseri Dian Widya Ningtyas Dzulvina Utami Dzulvina Utami Dzurratun Nafisah Ega Parastra Maurinho Ega Parastra Maurinho, Ega Parastra Eka Novanti Eka Novanti, Eka Elok Waziiroh Endah Trinafianita Endrika Widyastuti Eriyanto Yusnawan Erni Sofia Erryana Martati Feronika Heppy Sriherfyna Feronika Heppy Sriherfyna Firda Yusrina Guntur Prasetyo Guntur Prasetyo Guntur Prasetyo Hanny Nurhalimah Hanny Nurhalimah Henita Listianing Raji Putri Henita Listianing Raji Putri, Henita Listianing Raji Hera Sisca Prasmita, Hera Sisca Heri Wahyono Heri Wahyono I Ketut Suada Ika Nur Fauzziyah Ika Nur Fauzziyah, Ika Nur Indira Nur C. Itsna Zaky Zumroh Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jayanti, Theresia Vania Jhauharotul Muchlisyiyah Jhauharotul Muchlisyiyah, Jhauharotul Kemala Febrianti Kemala Febrianti KIKI FIBRIANTO Lailatul Fitriani Lailina Mufida Lailina Mufida Leenawaty Limantara M Wahid Wahyu Kurniawan Maramy, Neyla Vista Marcelia, Ela Mega Ayu Bunga Dewi Mega Leny Puspitasari Mega Leny Puspitasari Mey Etika Mey Etikasari Miptakhul Hudha Miptakhul Hudha Mochamad Afif Sholichudin Mochamad Afif Sholichudin, Mochamad Afif Muhammad Fawzul Alif Nugroho Muhammad Fawzul Alif Nugroho Musthikaningtyas Retno Palupi Musthikaningtyas Retno Palupi Nabilah Mei Wulandari Nabilah, Anjar Asmarani Widya Naomi Megananda Mulyadi Naomi Megananda Mulyadi, Naomi Megananda Nela Purwani Septiyanti Nela Purwani Septiyanti, Nela Purwani Nia Rochmawati Nia Rochmawati Nia Rochmawati Nike Nurlaily Fitria Nirmala Nurhasanah Nirmala Nurhasanah Nirmala Nurhasanah Novita Wijayanti Novita Wijayanti Novita Wijayanti Novita Wijayanti Nur Ida Panca Nugrahini Nurul Abidah Nurul Abidah Nurul Fahmi Rizkia Nurul Fahmi Rizkia, Nurul Fahmi Okkie Dhyantari Okkie Dhyantari Pandu Salim Hanafi Pawestriaji, Raihanurrabb Prajwalita Rukmakharisma Rizki Prajwalita Rukmakharisma Rizki Pramita, Hera Sisca PRASETYAWAN YUNIANTO Pratiwi, Devitasari Dian Puruhito Widinugroho Putri Puncak Anjani Putri Puncak Anjani Rachmad Rizal Yulianto Rachmad Rizal Yulianto Rahma Maya Safitri Rani Puspitasari Renny Dwi Puspitasari Renny Indrawati Renny Indrawati, Renny Retno Wulansari Rika Ersalia Rizca Dwi Jayanti Rizki Amelia Rizki Amelia Robbit Farid Wajdi Rofiqoh Fajarwati Saadatul K.S Sabrina W Purbasari, Sabrina W Sapitri, Nia Shelly Andrianty Siti Narsito Wulan Sofie Imsa Fitriyaningtyas Sofie Imsa Fitriyaningtyas Sudarma Dita Wijayanti Sudarma Dita Wijayanti Sudarma Dita Wijayanti Syafrilia, Rosita Mega Syafrilia, Rosita Mega Tabita Hasian Tara Viantya Wulansari Wafa, Nurul Widya D.R. Putri Widya Dwi Rukmi Wijayanti, Novita Paskarinda Wijayanti, Novita Wijayanti Wijayanti, Novita Wijayanti Winda Rein Nimas Tasia Winda Rein Nimas Tasia Wulandari, Diana Candra Yulina Lailatul Maslukhah Yulina Lailatul Maslukhah Yunia Galih Purwaningdyah Yunia Galih Purwaningdyah

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