Article Per Year (5 Year)
p-Index From 2020 - 2025
3.011
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) E-Jurnal Medika Udayana JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Medical Journal of Indonesia Jurnal Media Gizi Indonesia (MGI) The Indonesian Journal of Public Health Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Ilmiah Universitas Batanghari Jambi Amerta Nutrition Media Gizi Kesmas Indian Journal of Forensic Medicine & Toxicology Jurnal Kesehatan Tambusai Makara Journal of Health Research Jurnal Widya Medika
Bambang Wirjatmadi
Departemen Of Public Nutrition, Faculty Of Public Health, Airlangga University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 52 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : International Journal of Public Health Science (IJPHS)

 1 
Hepatoprotective Effect of Mangosteen Peel Extract on Borax-Induced Male Rats Yunita Satya Pratiwi; Bambang Wirjatmadi; Mangestuti Agil; Merryana Adriyani; Supriyadi Supriyadi
International Journal of Public Health Science (IJPHS) Vol 5, No 3: September 2016
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.05 KB) | DOI: 10.11591/ijphs.v5i3.4798

Abstract

The aim of this study was to determine the hepatoprotective effect of mangosteen peel extract (MPE) on borax-induced male rats. Hepatoprotective effect is represented by the variables of liver weight, SGOT (Serum Glutamic oxaloacetic transaminase) and SGPT (Serum Glutamic Pyruvate Transaminase). The true experimental study used randomized separated pretest-posttest control group design. MPE was made with 50% ethanol and 0.5% carboxymethyl cellulose-sodium (CMC-Na) stabilizer solutions. Studied groups included three control groups (positive, negative pretest and posttest) and three experimental groups (MPE dose of 200 mg/kg, 400 mg/kg and 600 mg/kg rats body weight (BW)). Samples consisted 36 male rats. The length of intervention was 16 days by providing borax, and then MPE was started on day 3 (in 3 experimental groups). Results showed that up to 16th day the SGOT tended to decrease (α <0.05), while the SGPT levels was stable, and so was the liver weight. Thus, up to day 16 the MPE was generally able to provide hepatoprotective effects mainly based on the variable SGOT in doses of 200 and 400 mg/kg. It has been proved that liver function of the rats was still relatively normal. This is in relations to the antioxidant potential of the MPE polyphenols.
Co-Authors Ade Saputra Nasution Adriani, Meriyana Adriani, Merriyana Ahmad Nur Huda AMBARWATI, SEPTIANA Andriani, Merryana Annisa Rizka Oktavianita Aprilia Nurcahyaning Rahayu Astuti, Nanik Dwi Aulia, Kharina Auliannisaa, Alifia Ayuningtyas, Septiadeti Hidayati Bambang Purwanto Bambang Purwanto Bambang Purwanto Cindy Claudia Nurulita Civana Dea Alnanda Cut Athira Sauma D.A. Liona Dewi Damayanti, Adelina Elsa Desy Prasetya, Desy Dwi Putra, Kartika Wahyu Dwi Winarni Etha Rambung Fara Disa Durry Fatifa Asmarani, Fatifa Haqqelni Nur Rosyidah INDROPO AGUSNI Isaura, Emyr Reisha Jujuk Proboningsih, Jujuk Kadek Tresna Adhi Kirana, Dhea Sukma Kuntoro Kuntoro Kurniasari, Nadya Putri Kusuma, Anindita M. Dodi F Priaminda M., Soenarnatalina Mangestuti Agil Maria Widijanti Sugeng Meirna Dewita Sari Merryana Adriani Merryana Adriyani Minarni Wartiningsih Mohammad Z. Rahfiludin Nanik Dwi Astuti Novera Herdiani, Novera Novita Eka Hardini Nur Nashriana Jufri Nuraini, Sekarsari Oktovina Rizky Oktovina Rizky, Oktovina Pratama, Dafa Azhari Priaminda, M Dodi F Pudji Astutik, Pudji Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah, Rahmi Syarifatun Retno Larasati Rina Wasesa Aprilia Lazulfa Rinda Istiqumilaily Setiarsih, Dini Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Soenarnatalina M. Sri Hartiningsih Sri Hartiningsih Sri Sumarmi Supriyadi Supriyadi Suryadinata, Rivan Virlando Susanti, Yuyun Erlina Wardani, Karmila Ayu Yoes P. Dahlan Yunita Satya Pratiwi Zahirah, Fildza Zolla Gracia Amardiani