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All Journal Sport and Fitness Journal Buletin Udayana Mengabdi Majalah Ilmiah Fisioterapi Indonesia Jurnal Epidemiologi Kesehatan Komunitas Bali Anatomy Journal

Nila Wahyuni

Departemen Ilmu Faal, Fakultas Kedokteran Universitas Udayana,Denpasar,Bali

Author-ID : 429653

Decision Sciences, Operations Research & Management Education Health Professions Medicine & Pharmacology Neuroscience Public Health Social Sciences

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PENINGKATAN HIGH-SENSITIVE CARDIAC TROPONIN (HS-CTN) SETELAH LATIHAN INTENSITAS TINGGI YANG INTENSIF Indira Vidiari J; Nila Wahyuni; I Putu Adiartha Griadhi
Sport and Fitness Journal Volume 6, No.3, September 2018
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

ABSTRACTThe role of exercise as a strategy for prevention, management and therapy in cardiovascular disease has been well described, but in some studies, it has been suggested that there is an increase in biomarkers in cardiac damage or cardiac troponin (cTn) after intensive, high-intensity exercise in healthy individuals. Several studies have shown significant increases in cardiac troponins after different types of exercise. The latest meta-analysis, showing that high-sensitivity cardiac troponin (hs-cTn) increases in about 83% of individuals after long and intensive exercise. The current pathophysiology of hs-cTn is not well understood. Several hypotheses have been proposed, such as transmembrane leakage from cytoplasmic free cTnT and cTnI or decreased troponin clearance from plasma, both caused by overloading of free radicals, myocardial stretching, elevated core temperature, or alteration of pH. Further research is needed with a full prospective study to evaluate the underlying pathophysiology of enhancing high sentivity cardiac troponin (hs-cTn) is an effective strategy for preventing or limiting cardiac injury and sport exercise safe for heart.Keywords: cardiac Troponin (cTn), high sensitivity cardiac troponin (hs-cTn), high intensity intensive exercise

EFEK YOGA TERHADAP KOMPONEN BIOMOLEKULAR PADA PROSES CELL AGING Nila Wahyuni
Sport and Fitness Journal Vol 8 No 2 (2020): Volume 8, No. 2, Mei 2020
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Pada dekade belakangan ini terjadi peningkatan yang signifikan pada prevalensi penyakit yang berhubungan dengan gaya hidup seperti depresi, diabetes mellitus, penyakit kardiovaskular, kanker, dan infertilitas. Penyakit ini sangat berhubungan dengan percepatan proses cell aging. Yoga dapat efektif dalam memperlambat proses cell aging dengan mengubah kadar berbagai biomarker yang berperan dalam proses cell aging Adapun metode penulisan yang digunakan adalah dengan studi literatur artikel mengenai efek yoga terhadap komponen biomolekuler dalam proses aging sel. Yoga dapat memperlambat proses seluler dan biological aging melalui penurunan produksi ROS, dan mempengaruhi stabilitas panjang telomer, mempengaruhi aksis hipotalamus-pituitari-adrenal (HPA aksis). Yoga efektif dalam mengubah kadar cardinal biomarker dan metabotrophic biomarker dalam darah terkait proses cell aging. Yoga juga efektif dalam menjaga kadar growth hormone dan dehydroepiandrosterone sulfate yang merupakan endocrine marker dari proses aging.

POLIMORFISME GEN ALPHA ACTININ-3 (ACTN 3) BERHUBUNGAN DENGAN MUSCLE PERFOMANCE ATLET Nila Wahyuni
Sport and Fitness Journal Volume 7, No.3, September 2019
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Background: The performance of professional athletes is very important for the achievement of athletes. The athlete's performance is influenced by various factors, namely environmental factors such as training, diet and sociocultural. One important factor that also affects the performance of athletes is genetic factor that are currently being studied. One of the genetic factors believed to play a role in athlete's performance is the Alpha Actinin-3 gene (ACTN 3). Purpose : to examine how the Alpha Actinin-3 (ACTN 3) gene polymorphism causes variation among individuals in athletic muscle performance. Method : study literature. Result : The ACTN 3 gene codes for the ?-actinin-3 protein which plays a role in producing a large force of contraction (rapid forceful contraction). The genetic variation of the ACTN 3 gene causes several variants of the ACTN 3 gene that play a role in the athlete's muscle performance.Keywords: Polymorphism, ACTN Gen 3, Muscle performance.

PEMULIHAN BERENANG LAMBAT GAYA BEBAS LEBIH EFEKTIF DIBANDINGKAN DENGAN PEMULIHAN BERENANG LAMBAT GAYA DADA DALAM MEMPERCEPAT PEMULIHAN DENYUT NADI SETELAH LATIHAN MAKSIMAL PADA ATLET RENANG PRIA GRUP RENANG BAYUSUTA DI DENPASAR Nila Wahyuni; Ketut Tirtayasa; Susy Purnawati
Sport and Fitness Journal Volume 2, No.2, 2014
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.282 KB)

The swimmer in Indonesia is still very difficult to compete with world athletes who constantly surge achievement. One reason is the lack of understanding of proper recovery methods or effective in supporting achievement that is slow swimming active recovery method. This study aims to prove the differences of effectiveness of slow frontcrawl swimming recovery with a slow breaststroke swimming recovery to accelerate pulse rate recovery of male Bayusuta swimmer group in Denpasar. Experimental research was done with the method of randomized pre and post test control group design, conducted on February 2014. Samples were selected by simple random sampling . The two intervention groups with each group of 17 samples that randomized selected. The first group was given intervention as slow frontcrawl swimming and the second groups given intervention as slow breaststroke swimming after maximal exercise 50 meter sprint swimming . Pulse rate recovery was measured using Brouha method that is pulse rate in the first minute until the fifth minute. Statistical analysis with the Wilcoxon test showed a decrease in pulse rate in both groups from the first minute until the fifth minute showed a significant decrease (p < 0,05). Based on the Mann Whitney test pulse rate recovery in the first minute and the second showed no significant difference ( p > 0,05 ), while the third to fifth minute pulse recovery in both groups showed significant differences ( p < 0,05 ) . The decrease of pulse rate in both groups in the first minute until the fifth minute showed significant results ( p < 0,05 ). In conclusion is slow freestyle swimming recovery methods is more effective than slow breaststroke swimming recovery method in accelerate swimmer pulse rate recovery. The results of this study are expected to increase the knowledge of coaches and swimmer to be able to do a proper recovery methods.

HUBUNGAN AKTIVITAS FISIK TERHADAP KEKUATAN GENGGAMAN DAN KECEPATAN BERJALAN PADA LANSIA DI KELURAHAN PANJER Vida Nanda Chattalia; Indira Vidiari Juhanna; Made Hendra Satria Nugraha; Nila Wahyuni
Sport and Fitness Journal Vol 8 No 3 (2020): Volume 8, No. 3, September 2020
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/spj.2020.v08.i03.p13

Pendahuluan: Penuaan menyebabkan perubahan struktur dalam tubuh manusia. Salah satunya adalah perubahan struktur otot sehingga menyebabkan penurunan kekuatan otot. Menurunnya kekuatan otot anggota gerak atas maupun bawah dapat mempengaruhi kemampuan fungsional seseorang karena terjadi penurunan kekuatan genggaman dan kecepatan berjalan. Memasuki masa lansia menyebabkan seseorang sulit untuk beradaptasi dengan lingkungan dan terlalu menutup diri dengan dunia luar. Padahal aktivitas fisik penting untuk dilakukan karena aktivitas fisik mampu meningkatkan kekuatan otot. Tujuan Penelitian: Mencari hubungan variabel aktivitas fisik terhadap kekuatan genggaman dan kecepatan berjalan pada lansia di Kelurahan Panjer. Metode: Penelitian menggunakan studi observasi analitik secara cross sectional, dilakukan di Panjer dari Maret 2019 – Mei 2019. Penelitian ini menggunakan subjek sebanyak 100 orang. Pengumpulan data dilakukan dengan mengukur aktivitas fisik menggunakan kuesioner Baecke Index, kekuatan genggaman menggunakan Hand-Grip Dynamometer dan pengukuran kecepatan berjalan dengan mengukur waktu berjalan pada lintasan sepanjang 4 meter. Hasil: Didapatkan p sebesar (p=0,000) untuk kekuatan genggaman dan (p=0,001) untuk kecepatan berjalan dari hasil uji chi-square. Uji hipotesis selanjutnya adalah korelasi kanonikal untuk menganalisis hubungan untuk semua variabel. Pada perhitungan analisis data, diperoleh hasil canonical loading sebesar 0,98531 untuk kekuatan genggaman, -0,69323 untuk kecepatan berjalan dan 1,00000 untuk aktivitas fisik sehingga semua hasil lebih tinggi dari nilai minimum 0,5. Kesimpulan: Berdasarkan hasil penelitian dan uji statistik tersebut maka dapat disimpulkan, (1) ada hubungan antara aktivitas fisik dengan kekuatan genggaman, (2) ada hubungan antara aktivitas fisik dengan kecepatan berjalan, dan (3) ada hubungan terhadap semua variabel. Kata kunci : lansia, kekuatan genggaman, kecepatan berjalan, aktivitas fisik.

EFEKTIVITAS LOW POWER LASER TERAPI DAN PROPRIOCEPTIF NEUROMUSCULAR FACILITATION PADA ULKUS DIABETIKUM DERAJAT 2 Made Hendra Satria Nugraha; Nila Wahyuni; Putu Ayu Sita Saraswati
Sport and Fitness Journal Volume 7, No.2, Mei 2019
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Diabetic ulcers are one of the most severe complications of diabetes in people with diabetes mellitus. When examined through the International Classification of Function (ICF) approach, there are several problems associated with diabetic ulcers, including: the presence of pain, limited movement, open wounds, loss of sensory sensation or motor ability. There are some modalities can be used to help these problems, namely by using laser and therapeutic approaches such as the application of proprioceptive neuromuscular facilitation (PNF). The method of this paper is an article review by using secondary data taken from research journals which are related to the effectiveness of the use of low power laser therapy and proprioceptive neuromuscular facilitation in diabetic ulcer patients. The primary effect of laser usage on cell is increasing oxidative metabolism to produce more ATP, which ultimately leads to the normalization of cell function, pain relief, and wound healing. PNF is a method of enhancing neuromuscular movement and facilitation to facilitate muscle contraction. This method has the primary goal of achieving individual needs, and thus can perform functional movements, through facilitation, inhibition, strengthening and relaxation of muscle groups. Based on the literature review, it can be concluded that: (1) Low power laser therapy is effective in repairing wounds in patients with grade 2 diabetic ulcers, (2) Proprioceptive Neuromuscular Facilitation (PNF) is effective in improving sensory and motor neuronal conduction associated with ankle movement in grade 2 diabetic ulcers, and (3) The combination of low power laser therapy and Proprioceptive Neuromuscular Facilitation is effective in improving the limitations of motion and function of grade 2 diabetic ulcers.

OLAHRAGA DAPAT MENINGKATKAN FUNGSI KOGNITIF MELALUI MODULASI EPIGENETIK EKSPRESI GEN BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) Nila Wahyuni; Made Hendra Satria Nugraha; Indira Vidiari Juhanna
Sport and Fitness Journal Volume 6, No.3, September 2018
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

ABSTRACTExercise may improve cognitive function and slow the onset of neurodegeneration, but the underlying mechanism had not yet known certainly. The purpose of this paper is to know the mechanism of exercise in improving cognitive function in terms of biomolecular aspects. The method of this paper is literature study of articles about the benefits of exercise in improving cognitive function in terms of biomolecular aspects. Cognitive function is a function related to perception, learning process, concentration, memory and problem solving. Exercise is useful for improving cognitive function mediated by a neurotropin-brain brain-derived neurotrophic factor (BDNF). BDNF has important role in neural plasticity, nerve excitability, and especially in learning process and memory improving. Exercise can improve cognitive function by inducing increased BDNF expression that occurs through the mechanism of epigenetic regulatory change. The change in epigenetic regulation caused by exercise through DNA methylation, which increase the expression of BDNF mRNA in the hippocampus. The change in epigenetic regulation caused by exercise, which also increase the expression of BDNF mRNA is a histone modification. The increased expression of mRNA in the hippocampus is not only increase synapse plasticity in the hippocampus area but also synapse transmission, which lead to the increasing of molecules expression related to learning and memory.Keywords: Sport, Brain-derived neurotrophic factor (BDNF), Epigenetic.

THE AEROBIC EXERCISE INCREASES COGNITIVE FUNCTION BIOMARKER, KLOTHO PROTEIN, IN ALZHEIMER DISEASE Emilia Eka Arrianti; Fransisca Natalia; Melisa Ayu; Kaisa Lana Afida; Lina Meylyn Shine; Nila Wahyuni; I Putu Gede Adiatmika
Sport and Fitness Journal Vol 10 No 2 (2022): Volume 10, No. 2, May 2022
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/spj.2022.v10.i02.p05

Aging is an inevitable process in human. It causes deterioration of many organs in human bodies such as the brain. The most common pathological aging condition in the brain is Alzheimer’s disease. This disease is the leading cause of deficits in short term memory, praxis, visuospatial, and executive function. It can impair cognitive function in older adults. A lot of intervention has been studied to treat Alzheimer’s disease. One of them is the aerobic exercise. Some studies find aerobic exercise increases the anti-aging protein, klotho protein. Klotho is a systemic-biomarkers that has an important role in sustaining cognitive function and brain integrity. The level of plasma klotho protein is increased by doing aerobic exercise moderately for 12 weeks. The increase of klotho protein improves memory formation and hippocampus function. In Alzheimer’s disease, klotho protein has the ability to lower the formation of neurofibrillary tangles. Hence, aerobic exercise is an essential intervention to improve cognitive function in Alzheimer’s disease patient.

THE TAI CHI ROLES IN REDUCING FATIGUE, PAIN, AND TNF-a PLASMA LEVEL ON BREAST CANCER PATIENTS: A SYSTEMATIC REVIEW Putri Yekti Budi Asih; I Putu Edra Putra Indrawan; Andhika Putri Perdana; Putu Ratna Candra Puspita; Vera Pravitasari Susila; Nila Wahyuni; I Putu Gede Adiatmika
Sport and Fitness Journal Vol 10 No 2 (2022): Volume 10, No. 2, May 2022
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/spj.2022.v10.i02.p06

Background: Tai Chi and many other Mind-body therapies have been very popular over the last few decades as useful tools for reducing stress and improving health. These methods are non-invasive and inexpensive. There are several reports showing that Tai Chi (TC) can regulate the host's immune system in many illnesses. This review summarizes the Tai Chi’s influence on breast cancer (BC) patients. Survivors of breast cancer often experience symptoms that reduce their quality of life during and after treatment, such as cognitive dysfunction, fatigue, sleep disturbances, depression, pain, and weight gain. The proinflammatory biomarkers like TNF-a, IL-1, IL-6 which activated through the central nervous system were believed inducing fatigue, pain , and other complications that caused hidarance on life activity. This becomes a serious problem as the number of survivors increases. The results of most studies show that Tai Chi reduced fatigue, pain, plasma levels of TNF-a and overall quality of life in breast cancer patients. Objective: To identify and evaluate the effect of TC training on inflammatory biomarkers, especially TNF-a, pain, and cancer-related fatigue (CRF) in breast cancer patients. Methods: Journal searching processes were performed through five electronic databases (ProQuest, Sciencedirect, PubMed, Google Scholar, and Sage Publications) and restricted from 2012 to 2022. The search strategy on the electronic databases was using terms like 'tai ji', 'tai chi', 'tumor necrosis factor-alpha', 'Interleukin-6', 'fatigue', 'pain', 'breast cancer', ‘biomarker’, 'TNF', 'TNF-a', and 'TNF-alpha'. The limitation of the study was only using academic journals and limited to Tai Chi training as an intervention. Reviewers obtained as many as 1.557 research journals. Then the reviewers analyzed the journal's contents obtained based on the eligibility of the topics, indexes or journal ratings through the Scimagojr website with journal criteria that met Q1 and Q2 quality, sample size, results from each journal, and limitations that occurred. Result: 15 journals were chosen to be reviewed and discussed about the intervention of Tai Chi, research methodology and study results using pain, fatigue and TNF-a biomarker. Conclusion: Tai Chi seems to be effective to reduce pain, cancer-related fatigue, and improves quality of life for breast cancer patients. accepts to TNF-a level plasma seems to be no different between usual care dan Tai chi practice. Moreover, it requires rigorous methodologies and randomized controlled trials to provide more reliable evidence.

A THE EFFECT OF YOGA AND MINDFULNESS MEDITATION ON ALPHA-AMYLASE LEVEL Brigitta Brigitta; Latisha Lubianca; Jessica Jessica; Tania Rosa; Eka Diah; Nila Wahyuni; I Putu Gede Adiatmika
Sport and Fitness Journal Vol 10 No 2 (2022): Volume 10, No. 2, May 2022
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/spj.2022.v10.i02.p02

In recent years, a lot of behavioral studies have shown that physical exercise and yoga have a positive impact on one’s physical and mental health. Yoga, which is increasingly used in the clinical setting of various mental and physical health problems, especially stress-related illnesses and concerns, has shown promising effects. This research is focused on evaluation of the stress levels in one’s body by measuring the levels of salivary stress marker alpha-amylase in accordance with yoga and mindful meditation. This study will focus on literature review using Boolean operator with databases from ScienceDirect, Pubmed, and Cochrane.

Co-Authors A A Ayu Tri Bhuana Komala Sari A A Indah Puspita Sari A.A.Istri Firasti Widyaratni Agung Istri Dewi Agung Wiwiek Indrayani Amalia Marza Anak Agung Sagung Dhriti Anggita Saraswati Arnaya Andhika Putri Perdana Ari Wibawa Aria Wibawa Ayu Putri Tantriyani Ayu Riesky Brigitta Brigitta D A A Diah Hadiningrat Dewi, Anak Ayu Nyoman Trisna Narta Dwi Jayanti Pringgadani Eka Diah Elfiera Kang Emilia Eka Arrianti Esra Nanda Rehulina Faustina Theresa Fiqhi Dhamiery Haniefah Effendi Fransisca Natalia Gede Parta Kinandana Ghanana Zuhadawa I Gede Donny Hendrawan I Gede Puspa Anom I Gusti Ayu Artini I Gusti Ngurah Agus Putra Mahardana I Kadek Adi Satya Nugraha I Made Krisna Dinata I Made Muliarta I MADE MULIARTA . I Made Niko Winaya I Nyoman Adi Putra I Putu Adiartha Griadhi I Putu Edra Putra Indrawan I Putu Eka Widyadharma I Putu Gede Adiatmika I Putu Gede Angga Winata I Putu Sutha Nurmawan I Putu Yudi Pramana Putra I Wayan Gede Sutadarma I Wayan Sugiritama Ida Ayu Citra Ratnasari Ida Ayu Dewi Wiryanthini Indira Vidiari J Indira Vidiari Juhanna Inne Melani Iwan Susanto Jessica Jessica Kadek Dwi Pradnya Lestari Kadek S Prima Dewi S Kaisa Lana Afida Karina Mutiara Kartika Sutanto Kenny Andrian Ketut Tirtayasa Komang Ayu Widiyantari Komang Putri Aprilia Latisha Lubianca Lina Meylyn Shine Luh Dwi Erma Krismawati Luh Made Indah Sri Handari Adiputra Luh Made Indah Sri Handari Adiputra Luh Putu Ratna Sundari Luh Putu Ratna Sundari M Widnyana Made Aditya Prawira Arthawan Made Hendra Satria Nugraha Made Rendra Wisnu Rahasbistara Made Satria Ambarsika Melisa Ayu Mohammad Kurniawan Monica Caroline Molenaar Nanang Masrani Nanda Putra Wiguna Ni Kadek Mira Wirayani Ni Ketut Rake Putri Saraswati Ni Komang Ayu Juni Antari Ni Luh Ayu Aris Ulan Devi Ni Luh Nopi Andayani Ni Made Deni Purnama Ni Made Wahyuni Dewi Ni Made Wira Tania Astarini Ni Wayan Tianing Ni Wayan Wahyuningsih Niko Winaya Nyoman Harry Nugraha Pricela Da Costa Putri Yekti Budi Asih Putu Adhika Satria Utama Wicaksana Aji Amertha Putu Ayu Sita Saraswati Putu Bayu Herlangga Putu Dyah Agustina Lestari Putu Ratna Candra Puspita Putu Sutha Nurmawan Sayu Aryantari Putri Thanaya Susy Purnawati Tania Rosa uh Made Indah Sri Handari Adiputra Vera Pravitasari Susila Vida Nanda Chattalia

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