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Cost-Effectiveness Analysis of Antihypertensive Combination Treatment in Chronic Kidney Disease Outpatients with Hypertension Hadning, Ingenida; Fauztina, Radhwa; Mustofa, Fajar A.
Indonesian Journal of Pharmaceutical Science and Technology 2025: Vol. 12 Suppl. 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12s1.57946

Abstract

The expense of managing CKD patients ranks second highest behind cardiovascular illness, with hypertension being the primary contributor to renal impairment. Maximizing the efficiency of therapeutic expenditures is essential. This study is to evaluate the cost-effectiveness of the combination of amlodipine 10 mg - candesartan 16 mg compared to the combination of candesartan 16 mg - furosemide 40 mg in patients with chronic kidney disease and hypertension. The research employed a non-experimental observational cohort design. The study was performed at both a private and a governmental hospital in Yogyakarta, Indonesia. Data were gathered retroactively using complete sampling. The inclusion criteria comprised outpatients with CKD-hypertension from January 2019 to October 2022, aged 18 years or older, who were undergoing combination therapy. The efficacy of therapy was evaluated by determining the number of samples achieving therapeutic objectives after 2 to 4 weeks. The mean expenditure was derived from monthly antihypertensive costs. The analysis of cost-effectiveness employed the Average Cost-Effectiveness Ratio (ACER) and the Incremental Cost-Effectiveness Ratio (ICER). The study comprised 50 samples, with 51% male participants and 66% aged 60 or older. Amlodipine and candesartan demonstrated superior efficacy (77%) and a reduced average cost of 101,095 IDR. The ACER for amlodipine and candesartan was 1,306 IDR, whereas for furosemide and candesartan it was 1,571 IDR. The amalgamation of amlodipine and candesartan is more economically advantageous than furosemide and candesartan.
Cost Analysis of Inpatient Stroke Treatment at Panembahan Senopati Bantul Regional General Hospital Based on INA-CBG's tariff in 2023 Hadning, Ingenida; Mouretha, Vrizca; Viviandhari, Daniek; Kusumaningtyas, Triana Arum
Pharmacon: Jurnal Farmasi Indonesia Volume 22, No 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.8551

Abstract

Stroke in Yogyakarta has the second highest prevalence rate in Indonesia, which requires long-term care and rehabilitation at a high cost. Stroke patients treated in classes 1, 2 and 3 are known to have experienced an increase in INA-CBG rates based on Minister of Health Regulation Number 3 of 2023. However, some hospitals often experience discrepancies between actual costs and INA-CBG's rates. Therefore, this study is the first to assess the cost of inpatient stroke treatment using the INA-CBG's tariff based on the Minister of Health Regulation Number 3 of 2023. This study aims to determine the average actual cost, the appropriateness of the average actual cost, and the difference in actual costs at a Regional General Hospital according to the INA-CBG's tariff in 2023. The research method used an observational design with a cross-sectional approach and retrospective data collection on stroke patients hospitalized from January to September 2023. Data were analyzed using the descriptive analysis method and one sample t-test if the data were normally distributed and the Wilcoxon test if the data were not normally distributed. Based on the study's results, it is known that the average actual cost does not exceed the INA-CBG tariff, so the hospital is profitable.
OPTIMIZING STRESS ULCER PROPHYLAXIS: A CLINICAL AND COST EVALUATION IN RSUD WATES INTERNAL MEDICINE WARD Octavia, Mega; Firmansyah, Ade Achmad; Hadning, Ingenida
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 2 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i2.1637

Abstract

The American Society of Health-System Pharmacists (ASHP) 1999 listed guidelines for providing stress ulcer prophylaxis (SUP) therapy as the standard of care for critical patients in the ICU. However, numerous studies have shown that most patients admitted to non-intensive care units continue to receive acid suppressant prescriptions, without appropriate indications or risk factors. This can lead to increased morbidity and increased patient care costs. This study aimed to determine the utilization profile of stress ulcer prophylaxis, its appropriateness, and the costs incurred by patients for SUP. This was an observational study with a cross-sectional design based on medical records. The study participants were inpatients from the Internal Medicine Polyclinic at Wates Hospital who met the inclusion criteria from January to December 2021. The study revealed that the H2 receptor antagonist (H2RA), proton pump inhibitor (PPI), sucralfate, and antacid groups received 57.9 %, 35.7%, 6.1%, and 0.3% of preventive drugs, respectively. Of the 215 patients, 76 received appropriate indications, whereas 139 received inappropriate indications based on the guidelines. During the study period, the cost of using stress ulcer prophylaxis for patients with appropriate indications was IDR 15,344,812 (76%), whereas the cost of using inappropriate stress ulcer prophylaxis was IDR 5,965,572 (28%) of the total cost. Factors such as the length of stay (LOS), type and cost of each medication, and frequency of medication administration can influence the high cost of inappropriately indicated patients. Keywords: Stress ulcer prophylaxis (SUP), inpatients at Wates Hospital, therapy evaluation, cost analysis
Enhancing The Understanding of Villagers in Semoyo Patuk Gunungkidul Yogyakarta Regarding Medicinal Chemical in Commercial Natural Products Hadning, Ingenida; Widayati, Aris
ADMA : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol. 6 No. 1 (2025): ADMA: Jurnal Pengabdian dan Pemberdayaan Mayarakat
Publisher : LPPM Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/adma.v6i1.5102

Abstract

The consumption of herbal medicine in Indonesia has attracted people since ancient times. The trend of consuming jamu is increasing along with the COVID-19 pandemic. Some studies mention that medicinal chemical ingredients are added to marketed natural medicines for a specific purpose, that is not allowed. These medicinal chemicals are known to cause side effects that are very harmful to the body. This reported program aims to improve knowledge regarding the dangers of medicinal chemicals added in marketed natural products. The participants of this program were 30 members of Argomoyo Sejahtera inSemoyo Village, Patuk, Gunung Kidul, Yogyakarta. This program was held on Saturday, May 4th, 2024, at Universitas Muhammadiyah Yogyakarta (UMY). This program was carried out through education about medicinal chemicals added in marketed natural products. Participants were given a questionnaire before and after the education to evaluate their knowledge regarding the delivered materials. Data of the pre and post test were analysed using paired sample t-test.  The results show that there is a significant increase in participants' knowledge, with a p-value of 0.017 (<0.05). These results indicate that education could effectively enhance knowledge about medicinal chemicals' dangers which are added to marketed natural products.
Edukasi Sistem Informasi Kesehatan Elektronik Untuk Kader Kesehatan Desa Tijayan Manisrenggo Jawa Tengah Ghozali, MT; Hadning, Ingenida; Winanta, Aji
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 1 (2020): Februari
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v4i1.2448

Abstract

ABSTRAKSistem Informasi Kesehatan (SIMKes) merupakan bagian penting dari sistem kesehatan suatu negara. SIMKes adalah bentuk utama Sistem Kesehatan Nasional (SKN) yang digunakan sebagai komponen dalam pembangunan berwawasan kesehatan. Sistem informasi yang tersusun dan terkonsep akan menghasilkan luaran yang baik dan membuat masyarakat tidak buta dengan dunia kesehatan. Teknologi informasi berkembang secara cepat dan berdampak pada semua aspek kehidupan, termasuk informasi kesehatan. Perkembangan teknologi saat ini berperan penting menjadi sebuah media bagi masyarakat milenial atau tenaga kesehatan untuk mendapatkan informasi mengenai gambaran kesehatan dan persebaran penyakit atau epidemiologi di wilayahnya masing-masing. Program Hibah Kemitraan ini bertujuan untuk melatih para kader kesehatan di setiap Padukuhan di Desa Tijayan Manisrenggo Jawa Tengah bagaimana cara membuat profil kesehatan dan peta persebaran penyakit di desa tersebut dan menyajikannya secara interaktif, edukatif, dan berbasis elektronik. Sasaran utama dalam program ini adalah kader kesehatan masing-masing padukuhan yang terdapat di Desa Tijayan, meliputi Bawangan, Candran, Pogaten, dan Sorobayan. Beberapa program kegiatan untuk mencapai tujuan tersebut meliputi pengumpulan data kesehatan yang didapat melalui survey atau sensus dan data yang sudah tersedia di pusat data kesehatan desa, penyuluhan tata cara pembuatan profil kesehatan dan peta persebaran penyakit, dan pelatihan penyajian data informasi kesehatan masyarakat secara interaktif dan edukatif. Program Hibah Kemitraan ini dapat membantu melengkapi profil kesehatan masyarakat dan meningkatkan kualitas SIMKes di desa mitra.Kata kunci: profil kesehatan; sistem informasi kesehatan; sisten kesehatan nasionalABSTRACTHealth Information System (HIS) is an important component of a country's health system. HIS is the main part of the National Health System, which is used as a pillar in health-oriented development. The structured and conceptual information system produces good outcomes and prevents people from the blindness of health matters. Information technology develops rapidly and impacts most of all aspects of life, including health information. Current technological developments play an important role as a media for millennial people or health professionals to get information about health information and epidemiology in their own region. This program aimed to train health cadres in each region of the Tijayan Manisrenggo Village, Klaten, Central Java, in addition to creating an electronic health profile and epidemiology map of the village and then presenting the profile interactively and educatively. The main targets of this program were health cadres in each region of the Tijayan Village, including Bawangan, Candran, Pogaten, and Sorobayan. Some main activities to achieve the objectives included collecting health data obtained through surveys or censuses and data already available in the health data center of the village, counseling procedures for creating an electronic health profile and epidemiology map, as well as training in the interactive and educative presentation of public health information data. This program helped complete the health profile and increase the quality of health information system in the partner villages.Keywords: health information system; health profile; national health system
Cost Analysis of Parturition with Sectio Caesarea at PKU Muhammadiyah Yogyakarta, Indonesia Hospital Based on INA-CBG’s Tariff in 2023 Hadning, Ingenida; Yumna, Nurina Faridah; Viviandhari, Daniek; Taufani, Indra Putra; Ha, Hai-Anh
JMMR (Jurnal Medicoeticolegal dan Manajemen Rumah Sakit) Vol. 14 No. 2 (2025): August 2025
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jmmr.v14i2.552

Abstract

The 2018 Riskesdas results showed that the prevalence of delivery by sectio caesarea in DIY was 23.1%. The high cost of sectio caesarea hinders access to public health, so the government implemented the INA-CBG's tariff. This study is the first to evaluate the INA-CBG's tariff based on the Permenkes RI Number 3 of 2023 for inpatient sectio caesarea delivery. This study aims to determine the difference between the cost of sectio caesarea delivery and the INA-CBG's tariff based on Permenkes RI Number 3 of 2023. Through this research, hospitals are expected to evaluate their services so that the costs of cesarean sections are under the INA-CBG's tariff. In addition, this research can serve as an evaluation of the INA-CBG's tariff for the government. This study used observational research methods and a cross-sectional approach. Data were obtained retrospectively by tracing medical records and treatment cost data of sectio caesarea patients from January to September 2023. Data were analyzed by descriptive analysis, one-sample t-test and one-sample Wilcoxon methods. The results of this study showed that the average actual cost was greater than the INA-CBG's rate, with significant differences in patients with class I code O-6-10-I, class II codes O-6-10-I and O-6-10-II, and class III code O-6-10-II, so that PKU Muhammadiyah Yogyakarta Hospital suffered losses.
Cost Analysis of Caesarean Deliveries under INA-CBG’s Tariff System in Jogja Hospital, Indonesia Hadning, Ingenida; Arditya, Zhafira As Syafa Putri
Journal of Public Health and Pharmacy Vol. 5 No. 3: NOVEMBER 2025
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v5i3.5889

Abstract

Introduction: This study aimed to determine differences in the average real cost of caesarean section with INA-CBG’s. This study is the first to use the latest INA-CBG's in 2023, so it can provide an overview of the implementation of INA-CBG's in 2023. The finding has the potential to provide recommendations for improving reimbursement policies and can guide the development of more effective financing models for hospitals and patients, particularly regarding caesarean section costs. In light of the growing global demand for cost efficiency in healthcare, this study provides valuable insights into optimizing financing structures and resource allocation. Methods: The study uses a quantitative research approach with retrospective data from sectio caesarea patient medical records in Jogja Hospital during January-September 2023. A total of 30 patients were enrolled, and data were collected through total sampling. Ethical approval was obtained from the hospital director with number 56/KEPK/RSUD/IX/2023 Results: The study's primary outcome was that the average real cost of the Caesarea section is higher than the INA-CBG's 2023. Furthermore, it was found that there was a significant difference between the average real cost of sectio caesarea and INA-CBG's in class 1 INA-CBG's code O-6-10-I (sig.0.001), class 3 INA-CBG's code O-6-10-I (Sig.0.000) and class 3 INA-CBG's code O-6-10-II (Sig.0.028). There are results of insignificant differences in class 1 INA-CBG's code O-6-10-II (Sig.0.180), class 2 INA-CBG's code O-6-10-I (Sig.0.089), class 2 INA-CBG's code O-6-10-II (Sig.0.180). Conclusion: This study shows that there is a significant difference between the real cost and the INA-CBG's on the payment of patient claims for inpatient services at Jogja Hospital. Our study contributes to understanding healthcare reimbursement issues by the difference between the average cost of sectio caesarea and INA-CBG's. Future research should address the evaluation of the factors that can cause the difference between the cost of sectio caesarea and INA-CBG's 2023, which will ultimately advance knowledge in the field of international health.
COST-EFFECTIVENESS ANALYSIS OF AMLODIPINE AND CANDESARTAN USE IN TYPE 2 DIABETES MELLITUS PATIENTS WITH COMORBID HYPERTENSION IN YOGYAKARTA, INDONESIA Hadning, Ingenida; Riswana, Nabila Uswah; Ardhani, Nariswari Cahya; Arini, Merita
Jurnal Farmasi Sains dan Praktis Vol 11 No 2 (May-August 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Type 2 diabetes mellitus, often accompanied by comorbid hypertension, necessitates expensive and prolonged treatment. Therefore, conducting a cost-effectiveness analysis is crucial to identify the most economically viable option by comparing the costs and therapeutic efficacy of amlodipine and candesartan in patients with type 2 diabetes mellitus and comorbid hypertension in Yogyakarta, Indonesia. This research aims to analyze therapy costs and effectiveness using pharmacoeconomic assessment, specifically calculating ACER (Average Cost-Effectiveness Ratio) and ICER (Incremental Cost-Effectiveness Ratio) values. The study uses a quantitative approach with retrospective data collection from patient medical records through total sampling. This research gathered data from 149 medical records. The cost-effectiveness analysis based on ACER values revealed the following: amlodipine 5 mg cost IDR 86; amlodipine 10 mg cost IDR 51; candesartan 8 mg cost IDR 571; candesartan 16 mg cost IDR 727. The ICER value of amlodipine 5 mg – candesartan 8 mg cost IDR 1,527; amlodipine 5 mg – candesartan 16 mg cost IDR 2,192; amlodipine 10 mg – candesartan 8 mg cost IDR –8454; amlodipin 10 mg – candesartan 16 mg cost IDR –5,979. The therapy is considered cost-effective when the ACER value is low, and the negative value of ICER indicates that the treatment has lower costs with greater effectiveness. So, using amlodipine 10 mg is the most cost-effective approach for reducing blood pressure in type 2 diabetes mellitus patients with comorbid hypertension in Yogyakarta, Indonesia.
Cost Analysis of Inpatient Stroke Treatment at PKU Muhammadiyah Yogyakarta Hospital Based on INA-CBG's Tariff in 2023 Hadning, Ingenida; Oktaviani, Aulia
Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i3.7261

Abstract

Stroke incidence in Yogyakarta Province is among the highest in Indonesia, frequently necessitating prolonged patient care and rehabilitation. The recent adjustment of INA-CBG's tariffs, as stipulated in Regulation of the Minister of Health of the Republic of Indonesia Number 3 of 2023, has increased reimbursement rates for inpatient hemorrhagic stroke (Classes 1, 2, and 3) and ischemic stroke (Class 1). Despite these revisions, many hospitals report disparities between operational costs and the INA-CBG's reimbursement rates. This study represents the first dedicated evaluation of INA-CBG's tariffs, specifically concerning the 2023 ministerial regulation, for inpatient stroke management. We aimed to ascertain the financial discrepancies between the average actual costs of inpatient stroke treatment and the updated INA-CBG's tariffs at PKU Muhammadiyah Yogyakarta Hospital. Employing an observational design with a cross-sectional approach, we retrospectively collected data from inpatient stroke patients treated between January and September 2023. Data analysis involved descriptive statistics and a one-sample t-test. The findings reveal that, for most cases, the average actual costs incurred by the hospital were significantly lower than the corresponding INA-CBG's tariffs, indicating a consistent profit margin for the institution.
Enhancing the Awareness of Indonesian Students in Hualien City, Taiwan, on Maintaining Health During their Studies from an Islamic Perspective Taufani, Indra Putra; Hadning, Ingenida; Haris, Fahni; Yang, Liang-Yo
Poltekita: Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2025)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v6i1.2820

Abstract

The effectiveness of students' diets, levels of exercise, and other healthy behaviors are strongly correlated with their learning processes, which in turn influence their academic performance. The real issue is the students' hectic schedules and precarious financial situations, which frequently harm their sleep and nutrition quality. This paper discussed the significance of teaching students the value of maintaining their dietary intake, physical activity levels, and sleep schedules. Students frequently put their academic activities and part-time jobs as priorities without considering the associated health risks. Therefore, we propose an activity integrating scientific and Islamic perspectives to educate students about health-related matters. The activity includes presentations on sleep patterns, nutrition, and hydration, integrating scientific research with teachings from the Quran and Hadith. Students are encouraged to engage in discussions and share experiences related to the material. When the community service program with Indonesian students in Taiwan was evaluated, it became clear that participants' knowledge and comprehension had significantly improved. According to the article's conclusion, the program successfully raised participant awareness of the value of staying healthy while studying from an Islamic perspective.