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All Journal Pharmaciana: Jurnal Kefarmasian Pharmacon Majalah Obat Tradisional Pharmascience PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Prosiding University Research Colloquium Innovative: Journal Of Social Science Research Maeswara: Jurnal Riset Ilmu Manajemen dan Kewirausahaan Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Global Management: International Journal of Management Science and Entrepreneurship
Anita Sukmawati
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Pharmacon

 1 
Efek Gliserin sebagai Humectan Terhadap Sifat Fisik dan Stabilitas Vitamin C dalam Sabun Padat Sukmawati, Anita; Laeha, Ms. Nur-ainee; Suprapto, Suprapto
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.5937

Abstract

Glycerin is a humectant that is used frequently for cosmetics, especially in soaps. This study was conducted to determine the influence glycerin on the physical properties of glycerin soap including pH, soap hardness, foam stability, and also on the stability of vitamin C in the soap during 8 weeks storage. Vitamin C is formulated in soap with various concentrations of glycerin i.e 5%, 10% and 20%. Evaluation of the soap preparations include a pH test, soap hardness, foam stability test and evaluation on the stability of vitamin C for 8 weeks and the results obtained will be statistically analyzed using SPSS version 16 for windows by the Kruskal-Wallis method on the results test of pH and soap hardness, and using one way ANOVA method for evaluating foam stability. The results showed that glycerol did not significant influence on the pH value of soap with a significance value of P = 0.26> 0.05, while increasing the concentration of glycerin in the soap increased products softness. The foam stability testing showed that the difference in the concentration of glycerin on soap had no significant effect on improving the stability of foam. The best foam stability was found in vitamin C soap containing glycerine 10%. Glycerin also affected the stability of vitamin C in the soap. The stability of vitamin C is increased related to the increasing glycerin concentration in soap as demonstrated in formula III, which contained 20% glycerin and had 49.48% reducing in level of vitamin C, while the soap containing glycerine 5 % and 10%, had decreased 77.98% and 60.67% respectively in level of vitamin C during the storage period of 8 weeks.
Karakterisasi Fisik dan Aktivitas Antioksidan Masker Wajah Gel Pell Off Yang Mengandung Sari Buah Naga (Hylocerus polyrhizus) Setiawati, Ririn; Sukmawati, Anita
Pharmacon: Jurnal Farmasi Indonesia Vol 15, No 2 (2018)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v15i2.7245

Abstract

Damaged skin due to free radicals from ultraviolet radiation can be prevented using antioxidants. Red dragon fruit (Hylocereus polyrhizus) containing antioxidants can be made into a peel off gel face mask using gelatin as a gelling agent to be applied easily to the skin. The purpose of this study is to determine the effect of various gelatin concentrations on the physical properties and antioxidant activity of peel off gels containing red dragon fruit juice. The peel off gels face mask were made using various gelatin concentration i.e 7.5% w/w (F1); 10% w/w (F2); and 12.5% w/w and containing 10% w/w red dragon fruit. The peel off gels then evaluated for physical properties and antioxidant activity using DPPH. The result showed that the increasing of the gelatin concentration would increase the drying time and adhesive ability of the peel off gels. The escalation of gelatin concentration from 7.5% w/w (F1) to 10% w/w (F2) did not affect the spreading ability of the peel off gel. However, the spreading ability of the peel off gel decreased with the increasing concentration of gelatin from 10% w/w (F2) to 12.5% w/w (F3). The antioxidant test of peel off gel had an average percentage of inhibition of 9.101% (F1); 12.469% (F2); and 15.109% (F3). Based on the results of physical properties and antioxidant activity showed that formula 2 was recomended.
Karakterisasi Fisik dan Aktivitas Antioksidan Masker Wajah Gel Pell Off Yang Mengandung Sari Buah Naga (Hylocerus polyrhizus) Ririn Setiawati; Anita Sukmawati
Pharmacon: Jurnal Farmasi Indonesia Vol 15, No 2 (2018)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v15i2.7245

Abstract

Damaged skin due to free radicals from ultraviolet radiation can be prevented using antioxidants. Red dragon fruit (Hylocereus polyrhizus) containing antioxidants can be made into a peel off gel face mask using gelatin as a gelling agent to be applied easily to the skin. The purpose of this study is to determine the effect of various gelatin concentrations on the physical properties and antioxidant activity of peel off gels containing red dragon fruit juice. The peel off gels face mask were made using various gelatin concentration i.e 7.5% w/w (F1); 10% w/w (F2); and 12.5% w/w and containing 10% w/w red dragon fruit. The peel off gels then evaluated for physical properties and antioxidant activity using DPPH. The result showed that the increasing of the gelatin concentration would increase the drying time and adhesive ability of the peel off gels. The escalation of gelatin concentration from 7.5% w/w (F1) to 10% w/w (F2) did not affect the spreading ability of the peel off gel. However, the spreading ability of the peel off gel decreased with the increasing concentration of gelatin from 10% w/w (F2) to 12.5% w/w (F3). The antioxidant test of peel off gel had an average percentage of inhibition of 9.101% (F1); 12.469% (F2); and 15.109% (F3). Based on the results of physical properties and antioxidant activity showed that formula 2 was recomended.
Efek Gliserin sebagai Humectan Terhadap Sifat Fisik dan Stabilitas Vitamin C dalam Sabun Padat Anita Sukmawati; Ms. Nur-ainee Laeha; Suprapto Suprapto
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 2 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i2.5937

Abstract

Glycerin is a humectant that is used frequently for cosmetics, especially in soaps. This study was conducted to determine the influence glycerin on the physical properties of glycerin soap including pH, soap hardness, foam stability, and also on the stability of vitamin C in the soap during 8 weeks storage. Vitamin C is formulated in soap with various concentrations of glycerin i.e 5%, 10% and 20%. Evaluation of the soap preparations include a pH test, soap hardness, foam stability test and evaluation on the stability of vitamin C for 8 weeks and the results obtained will be statistically analyzed using SPSS version 16 for windows by the Kruskal-Wallis method on the results test of pH and soap hardness, and using one way ANOVA method for evaluating foam stability. The results showed that glycerol did not significant influence on the pH value of soap with a significance value of P = 0.26 0.05, while increasing the concentration of glycerin in the soap increased products softness. The foam stability testing showed that the difference in the concentration of glycerin on soap had no significant effect on improving the stability of foam. The best foam stability was found in vitamin C soap containing glycerine 10%. Glycerin also affected the stability of vitamin C in the soap. The stability of vitamin C is increased related to the increasing glycerin concentration in soap as demonstrated in formula III, which contained 20% glycerin and had 49.48% reducing in level of vitamin C, while the soap containing glycerine 5 % and 10%, had decreased 77.98% and 60.67% respectively in level of vitamin C during the storage period of 8 weeks.
Study of Liquid Self-nanoemulsifying Drug Delivery System (L-SNEDDS) that Use Oleic Acid as the Oil Phase: Literature Review Lestari, Ratih Guswinda; Sukmawati, Anita
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23468

Abstract

Self-Nanoemulsifying Drug Delivery System (SNEDDS) is a nanoemulsion system that can be used to increase the bioavailability of drugs that are hardly soluble in water and have low bioavailability. Oleic acid, a saturated fatty acid that is found in many vegetable oils, is an oil that is often used for the oil phase in SNEDDS. Therefore, this review article aims to review, study, analyze and explore the optimum formula of SNEDDS that use oleic acid as the oil phase. The articles were searched via Google Schoolar, Science Direct, and Pubmed. The total number of articles is 464 articles. The total number articles that include exclusion criteria is 453 articles. The total article that use is 11 articles. SNEDDS, which uses oleic acid as the oil phase, produces droplet sizes of 19.75-190.03 nm with a polydispersity index of 0.278-0.532. Zeta potential value, only 2 articles have a zeta potential value above +/-30, that is mefenamic acid SNEDDS and furosemide SNEDDS. Overall, SNEDDS which uses oleic acid as the oil phase has a better dissolution and bioavailability profile compared to the commercial product or the pure drug. If solubility and bioavailability increase, it can increase the pharmacological activity of the drugs
Co-Authors A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Adellia Agustina Nur Saputri Andriyas Nisfiliyah Arifah Sri Wahyuni Arsanto, Hugeng Wimbo Asyhar Masyhuda Aysha, Miranda m Ayyun, Qurrota Azistyna, Delvi Yulia Bakar, Fazleen Izzany Abu Cholisoh, Zakky Clara Cendera Marthadilla Dewi Rahmawati DEWI RAHMAWATI Dwi Hernuningsih Elbira J.A Purnomo Evi Mulyani Farida, Rahayu Freddy Johannis Rumambi Haerani, Dian Hafizah, Nurul Hairi, Dewi Gulyla Hidayah Karuniawati Hilda Srivaliana Ilham Ika Trisharyanti Dian Kusumowati Indriyani, Yuvita Dewi Intan Nurhanifah Isna Vira Risdiyanti Iwan Purnama Laeha, Ms. Nur-ainee Lestari, Ratih Guswinda Lintang Karengga Ihsani Lintang Titian Cahya M. A., Rhinomuraena Makanoneng, Jacqueline Marisi Pakpahan Masyhuda, Asyhar Maulana, Fahmi Alief Mika Tri Kumala Swandari, Mika Tri Kumala Miranda m Aysha Ms. Nur-ainee Laeha Muhammad Aditya, Muhammad Muhammad Bakhtiar Mulyani, Risya Naibaho, Nora Nisfiliyah, Andriyas Nugraha, Adie Nur Aini Nurhanifah, Intan Nurhasan, Dede Oktavia Permata Fenthiadewi Palupi Finofasipa Patrick Patrick Peni Indrayudha Pratama, Ilham Okta Purbandari Ajeng Sarweningtyas Purnomo, Elbira J.A Putra, Handre Qurrota Ayyun Radixza Afiffatul Rohmanna Rajali, Ahmad Ramdani, Tasya Eka Ratna Yuliani Ratna Yuliani Razali, Roni Riauwati, Rossa Rifa Iztihara Rihi Hina, Bara Jonathan Ririn Setiawati Rohmanna, Radixza Afiffatul Rudianto Rudianto Salam, Bernadi Gamal Salsabila, Unik Hanifah Saputri, Adellia Agustina Nur Septiani, Adiva Metri Seran, Ardi Seran, Ardi Peterson Setiawati, Ririn Setyani, Yerika Nova Setyawan, Filippus Cahyo Setyo Nurwaini Sundari, Sri Suprapto Suprapto Tangkudung, Audrey G Tangkudung, Audrey G. Tri Mulyani Tri Mulyani Triyatno, Sabrina Azizah Umi Khasanah Umi Khasanah Wibowo, Danang Novianto Wijianto, Diski Wahyu Wikantyasning, Erindyah R. Yerika Nova Setyani Yumna Azzuhdiyah Yuvita Dewi Indriyani  Pakpahan, Marisi