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All Journal Jurnal Kimia (Journal of Chemistry) The Journal of Pure and Applied Chemistry Research JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Wiyata : Penelitian Sains dan Kesehatan GERVASI: Jurnal Pengabdian kepada Masyarakat Jurnal Pengabdian Al-Ikhlas Berkala Ilmiah Mahasiswa Farmasi Jurnal Farmasi Tinctura Sainsbertek Jurnal Ilmiah Sains & Teknologi Prosiding Seminar Nasional Universitas Ma Chung Jurnal Pengabdian Masyarakat Charitas Rafflesia Journal of Natural and Applied Sciences (RJNAS) Journal of Public Health Indonesian NAWASENA: Journal of Community Service Journal of Public Health Indonesian
Muhammad Hilmi Afthoni
Fakultas Farmasi Universitas Jember
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Development of Colloidal Silver-based Mercury Sensors in Whitening Cream Muhammad Hilmi Afthoni; Sherly Yunita; Eva Monica
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.272-279

Abstract

Background: Mercury, a hazardous heavy metal known for its toxicity to the human body, finds application in cosmetics due to its capacity to inhibit melanin formation. Traditional mercury analysis relies on resource-intensive and time-consuming instrumentation. Objective: This study aims to devise cost-effective and practical sensors for mercury detection. Methods: The sensor development process involves immobilizing the sensor onto paper, reacting it with mercury, scanning the outcome using a scanner, and subsequently quantifying RGB values using the ImageJ software. Results: Optimization of reagent concentrations gave a ratio of methylene blue, AgNO3, gallic acid, and ascorbic acid at 0.5:7:1.5:1 generating the best results. Additionally, pH optimization within the range of 5 to 9 demonstrates stability without necessitating the inclusion of a buffer solution. Notably, the blue variant exhibits superior responsiveness during concentration optimization. Characterization of the sensor reveals a response time of 3 minutes and minimal interference of 2.145% from other substances. The sensor exhibits a linearity range of 0.5-250 ppm, regression equation y = 8.603x + 21.124, an R-value of 0.994, and an exceedingly low p-value of 6.9924589548512 x 10-9. The sensor boasts a limit of detection (LOD) of 0.206 and a limit of quantification (LOQ) of 0.265, indicative of its precision. Further assessments reveal a percent relative standard deviation (% RSD) precision of 2.017% and a recovery rate of 96.14%. Conclusion: The sensor has exhibited stability for over one month under room temperature storage conditions. A comparison between the UV-Vis spectrophotometer and the sensor signifies no significant difference between the two methods.
Co-Authors Alfanaar, Rokiy Annisak Diana Agustun Ayu Merli Wahyuni Chandra, Melisa Dwi Chresiani Destiana Yoedistira Dzurriatul Maghfiroh E. Monica Ega Malia Jiska Eka Anggie Amalia Eka Anggie Amalia Erlinawati Santoso Erlinawati Santoso Eva Monica Eva Monica Eva Monica Eva Monica Feliadewi Ruth Fibe Yulinda Cesa Hafis Ridho Kurniawan Hasnidar Kestrilia Rega Prilianti llando, Ro Maria Sindy Marsha Anggita Amelia Martanty Aditya, Martanty Marvin Horale Pasaribu Mezaluna Aprilia moh lutfi, moh Mokhamat Ariefin Mustar Nababan, Jessicca Nurul Azmi Wibawanty P. N. Alfiyandri Rahmawati Wahyuning Utami Rara Wulandari Widagdo Reisya Diancayudha Rollando, Rollando Sherly Yunita Sugiani, Tina Sultan Arif Rahmadianto Susanto, FX. Haryanto Trianom Suryandharu W. Swastika Wahyuningsih Manurung, Tety Windra Swastika Yamtana Yamtana Yamtana Yamtana, Yamtana Yoedistira, Chresiani Yoshelina Setyaningrum Yuneta Yurida Ekawati Yurida Ekawati Yuyun Yuniarti, Yuyun