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All Journal PROSIDING SEMINAR NASIONAL MANDALA of Health Universa Medicina Jurnal Pengabdian Pada Masyarakat Journal Of Holistic Nursing Science Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Budimas : Jurnal Pengabdian Masyarakat Mandala of Health : A Scientific Journal Medical and Health Journal Journal of Applied Science for Pharmaceuticals and Health
Fajar Wahyu Pribadi
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Religion Agriculture, Biological Sciences & Forestry Humanities Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENINGKATAN SUSTAINABILITAS RANTAI NILAI BUDIDAYA LEBAH KLANCENG KELOMPOK MALANG JAYA Herwiyanti, Eliada; Yuniaty, Alice; Wahyu Pribadi, Fajar
BUDIMAS : JURNAL PENGABDIAN MASYARAKAT Vol. 7 No. 3 (2025): BUDIMAS : Jurnal Pengabdian Masyarakat
Publisher : LPPM ITB AAS Indonesia Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29040/budimas.v7i3.18195

Abstract

The community service program aims to improve the sustainability of the Trigona spp. cultivation value chain. The target group is the Malang Jaya Trigona spp. cultivation group, located in Pageraji Village, Cilongok, Banyumas. Established in February 2024, the Malang Jaya group faced challenges in production, organizational management, and marketing. Efforts to address these challenges included providing appropriate technology and innovation, providing outreach and training on organizational management, and marketing. The technology and innovation assistance provided included raw materials, components, and appropriate technology tools. All of the technological and innovation assistance has been handed over on July 26, 2025. Until the time this article was written, meaning approximately 50 days have passed, the Malang Jaya group has carried out the Trigona spp. cultivation process, planting longan and santos lemon tree seedlings, better product storage and packaging practices, as well as more orderly financial and administrative recording practices by using all the technology and innovation funded by the Grant of the Directorate of Research and Community Service, Directorate General of Research and Development, Ministry of Higher Education, Science, and Technology. Thus, slowly but surely, the Malang Jaya group will experience an increase in the sustainability of the Trigona spp. cultivation value chain.
Gambaran Fibrosis Tubulus Ginjal Tikus Putih (Rattus norvegicus) Hiperurisemik Yang Diberikan Bawang Hitam Fajar Wahyu Pribadi; Catharina Widiartini; Gita Nawangtantrini; Hidayat Sulistyo
Journal of Applied Science for Pharmaceuticals and Health Vol 1 No 2 (2024): Journal of Applied Science for Pharmaceuticals and Health (Desember)
Publisher : Centre of Applied Science for Pharmaceutical Science Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jasph.2024.1.2.14876

Abstract

Hyperuricemia can cause damage to the kidneys through activation of the inflammatory cascade and an increase in free radicals. The level of damage that occurs in the kidneys can be seen through the picture of renal tubular fibrosis. Black garlic contains s-alyl cistein (SAC), tetrahydro-β-carbolines, alkaloids, and flavonoids that are thought to inhibit the work of the xanthine oxidase enzyme so that it can reduce uric acid and repair kidney damage that has occurred. The short-term goal of this study was to determine the picture of renal tubular fibrosis in hyperuricemic white rats given black garlic. The long-term goal to be achieved is the use of black garlic for prevention and or overcoming the negative effects of hyperuricemia on the kidneys. Rats were grouped into five groups: positive control, allopurinol group, 240mg, 480mg and 960mg black garlic groups. Induction of hyperuricemia was carried out by injection of potassium oxonate and the addition of cow brain for 14 days, followed by treatment. At the end of the study, termination and organ harvesting will be done to examine the picture of renal tubular fibrosis. This study is an experimental study. The results showed that the administration of various doses of black garlic can reduce fibrosis in hyperuricemia white rats (Rattus novergicus).
Evidence Based Case Report: Comparison of Fixed-Dose Combinations Vs Separate Combinations of First-Line Antituberculosis Drugs in Patients With Drug-Sensitive Pulmonary Tuberculosis and Obesity Fajar Wahyu Pribadi; Agian Jeffilano Barinda; Nukman Syafrul Panigoro
Medical and Health Journal Vol 6 No 1 (2026): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.6.1.22052

Abstract

Pulmonary tuberculosis (TB) remains a global health problem, while obesity has the potential to affect the pharmacokinetics of rifampicin and the effectiveness of therapy. Although the WHO recommends a fixed-dose combination (FDC), its effectiveness compared to a single-drug formulation (SDF) in obese patients remains controversial. This Evidence-Based Case Report aims to evaluate the efficacy and safety of FDCs compared to SDFs in obese adult patients with drug-sensitive pulmonary TB. A literature search was conducted in PubMed, Cochrane, and Scopus, yielding four studies that met the criteria (three randomized controlled trials and one cohort study). A critical review revealed mixed results, with some studies supporting the non-inferiority of FDCs, while others indicated a risk of less favorable clinical outcomes. Based on the available evidence, the use of SDFs is more strongly recommended for obese patients with a suboptimal response to FDCs, as this approach has the potential to reduce the risk of underdosing and treatment failure through more optimal monitoring of dosage and clinical response
Co-Authors Afifah Afifah Agian Jeffilano Barinda Alice Yuniaty Aulia Salsabiela Dimo Hari Anggara Dody Novrial Dwi Utami Anjarwati Eliada Herwiyanti Eska Perdini, Eska Evy Sulistyoningrum Fareza, Muhamad Salman Gita Nawangtantrini Gita Nawangtantrini Hidayat Sulistyo Idsap Peramiarti Miko Ferine Muhammad Afif Nukman Syafrul Panigoro Panuntun, Hilmi Puguh Putri Nur'afni Sa'adah Robby Al Fauzy Setiawati - Thianti Sylviningrum Viva Ratih Bening Ati Wahyu Dwi Kusdaryanto Wahyu Siswandari Widiartini, Catharina Zahra Muthmainnah Komara