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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Farmasi Higea MEDIC MEdical Dedication Yayasan Cita Cendikiawan Al Khwarizmi Pharmaceutical Sciences and Research (PSR) Sciences of Pharmacy Jurnal Pengabdian Harapan Ibu (JPHI)
Neldi, Vina
Departemen Farmakologi Dan Farmasi Klinis, Sekolah Tinggi Ilmu Farmasi Padang, Padang, Indonesia
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DIVERSIFICATION OF HERBAL PRODUCTS BASED ON LOCAL WISDOM AS AN EFFORT TO PREVENT STUNTING FOR THE COMMUNITY OF OLAK KEMANG VILLAGE Kasmadi, Fathnur Sani; Maharini, Indri; Maimum, Maimum; Fitrianingsih, Fitrianingsih; Neldi, Vina; Astuti, Novia Tri; Perawati, Santi; Yuliawati, Yuliawati; Yuliandani, Yuliandani; Nurfadilah, Nurfadilah
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 2 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

Stunting, or chronic malnutrition, remains a significant public health challenge in Indonesia, impacting the cognitive and physical development of children. This community service project aimed to address this issue through a culturally sensitive and sustainable approach in the community of Olak Kemang Village, Jambi. The program focused on diversifying local wisdom-based herbal products to improve nutritional intake among pregnant women, lactating mothers, and children under five. The method involved a three-stage process: (1) socialization and nutritional education about stunting, (2) training on the hygienic processing of local plants rich in micronutrients, such as Moringa (Moringa oleifera) and Katuk leaves (Sauropus androgynus), and (3) a hands-on workshop on creating diversified, child-friendly products like herbal powders, fortified cookies, and puddings. Pre- and post-activity questionnaires demonstrated a significant increase in participants' knowledge and awareness of stunting prevention, from 67,4% to 90,58%. Participants also successfully produced several innovative herbal food products. This initiative highlights that empowering communities by integrating local knowledge with scientific principles is a promising and effective strategy for stunting prevention. Keywords: Stunting, community service, herbal product, nutrition, local wisdom.
Exploratory Study of Digoxin Safety Based on Pharmacokinetic Approach and Drug Interactions in Patients with Congestive Heart Failure Sadli, Nurul Kamilah; Perawati, Santi; Neldi, Vina; Astuti, Novia Tri; Pondawinata, Marizki; Humaira, Syaza Putri
Sciences of Pharmacy Volume 5 Issue 3 (2026)
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0502636

Abstract

Digoxin has a narrow therapeutic index, requiring close monitoring to prevent toxicity, particularly in patients with heart failure, polypharmacy, and impaired renal function. Due to limitations in therapeutic drug monitoring (TDM), we estimated digoxin serum levels using pharmacokinetic formulas based on creatinine clearance. This retrospective observational study aimed to conduct an initial risk screening by estimating digoxin concentrations, evaluating drug interactions, and assessing heart rate in 17 heart failure patients at a regional general hospital in Jambi (January–August 2025). Descriptive analysis revealed that 76% of patients were within the therapeutic range, while 24% exceeded it, with elevated levels correlating with higher creatinine serum and lower creatinine clearance. Common drug interactions involved furosemide, bisoprolol, and proton pump inhibitors, with spironolactone posing a severe risk. Clinically, bisoprolol combined with hypokalemia appeared associated with lower heart rates in patients with predicted toxic concentrations. While the formula-based pharmacokinetic approach serves as a useful exploratory initial screening tool, these findings require further validation through laboratory-based TDM and larger studies.
Co-Authors Anggelia Puspasari Efendi, M. Rifki Effendy, Sanezea Elisma Elisma Fitrianingsih Fitrianingsih Humaira, Syaza Putri Luri Mekeama M. Rifqi Efendi Maharini, Indri Maimum Muhammad Daffa Sonik Naurasyifa, Hairania Novia Tri Astuti Nurfadilah Nurfadilah Pondawinata, Marizki Priskila, Loury Puspa Dwi Pratiwi Putri Ramadhani Putri Ramadhani, Putri Rahman, Havizur Ramadani, Arum Kinasih Sadli, Nurul Kamilah Sani K, Fathnur Santi Perawati, Santi Suharjono Tarigan, Nadir Putra Indra Tengku Arief Buana Perkasa Tri Astuti, Novia Uce Lestari Widyawati, Dwi Yuliana Yuliana Yuliana Yuliana Yuliandani, Yuliandani