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Adita Silvia Fitriana
Program Studi Farmasi Program Sarjana, Universitas Harapan Bangsa
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Chemical analysis of Cyproheptadine Hydrochloride in appetite-stimulating herbs marketed in Banyumas regency: ensuring consumer safety Indarwati, Atika; Fitriana, Adita Silvia; Rahmawati, Nur
Journal of Natural Sciences and Mathematics Research Vol. 10 No. 1 (2024): June
Publisher : Faculty of Science and Technology, Universitas Islam Negeri Walisongo Semarang

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Abstract

Jamu, a traditional Indonesian herbal medicine, is widely used in traditional healing practices nationwide, including the Banyumas Regency. The Indonesian government has implemented restrictions that forbid the inclusion of medicinal compounds in jamu, as their unregulated usage poses possible health hazards. Cyproheptadine hydrochloride is a frequently encountered medicinal component in appetite-stimulating herbs. However, the extent of adulteration of cyproheptadine hydrochloride in appetite-stimulating herbs marketed in Banyumas Regency is undisclosed. This study purposed to analyze and quantify the presence of cyproheptadine hydrochloride in appetite-stimulating herbs that are available for sale in the Banyumas Regency. The aim was to inform customers about these herbs' possible pharmaceutical ingredient content. The study utilized a qualitative analysis of thin-layer chromatography (TLC) and a quantitative analysis with a UV-Vis spectrophotometer. Fourteen samples of appetite-stimulating herbs in powdered, capsule, and tablet forms were gathered from different areas within the Banyumas Regency. Qualitative analysis revealed cyproheptadine hydrochloride in two herbal samples, SNM TG and SNM AM. The quantitative examination revealed that the content of cyproheptadine hydrochloride in SNM TG was 10.92 mg/5g, whereas in SNM AM, it was 7.93 mg/5g. These findings indicate that there have been breaches of regulations, and individuals who ingest these herbs may be susceptible to health problems. Further investigation is required to analyze a broader range of appetite-stimulating herbal samples, particularly those in liquid form, to ascertain the level of contamination with cyproheptadine hydrochloride and provide essential data for health regulations.
Co-Authors Afni Mirlandari Afresa Bias Putri Enarga Afresa Bias Putri Enarga Al Mu’izzah, Nurul Alfaeni Salmatuzzahro Ali Djamhuri Aminurita, Agus Arni Nur Rahmawati Aurellia, Rizky Natasya Awal Tunis Yantoro Bambang Purwono Dessy Nawangsari Desy Nawangsari Desy Nawangsari Desy Nawangsari Dewi Rahmawati Dina Febrina dina febrina Dwi Novitasari Erni Lovianasari Galih Samodra Galih Samodra Hanif Zufrialdi Bagaskara Harno Dwi Pranowo Iga Melasasi Indarwati, Atika Khofifatul Muamanah Kurnia Panggih Rahayu Lestari, Afnida Dwi Munawarohthus Sholikha Murniati Murniati Nawangsari, Desy Nawangsari, Desy Nawangsari Nisa Nur Fadilah Noor Yunida Triana Nur Rahmawati Nur Rahmawati Rani Prabandari Riska Norma Sarita Royani, Sri Samodra, Galih Setyaji, Andy Anggoro Siti Haniyah Sri Royani Sri Royani Suryani, Roro Lintang Tanti Purwanti Tiwi Setianingrum Triana, Noor Yunida Triana, Noor Yunida Umayah, Dani Yatul