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All Journal Jurnal Geodesi Undip Mahaguru: Jurnal Pendidikan Guru Sekolah Dasar Jurnal Ilmiah Wahana Pendidikan Community Medicine and Education Journal Joong-Ki : Jurnal Pengabdian Masyarakat Jurnal Pendidikan dan Pengabdian Masyarakat Scientific Journal of Pediatrics VALUTA Jurnal Administrasi Bisnis, Manajemen dan Ekonomi Crown: Journal of Dentistry and Health Research Joong-Ki Joong-Ki
Firman Hadi
Unknown Affiliation
Religion Humanities Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Pengembangan Kualitas Guru Melalui Supervisi Pendidikan Demi Meningkatkan Mutu Pendidikan di Sekolah MTs Tahfidzul Qur’an Nurul Azmi Siti Fatimah Azzahro Simatupang; Firman Hadi; Fara Nabila Tania; Azhari Panjaitan; Raudhatul Jannah; Melin Andilla; Inom Nasution
Joong-Ki : Jurnal Pengabdian Masyarakat Vol. 2 No. 2: Mei 2023
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/joongki.v2i2.1661

Abstract

Educational organization of the director or supervisor is very important to increase the professional ability of the teacher. The purpose of this study was to investigate educational assistance programs to improve the quality of school teacher education in Madrasah Tsanawiyah Nurul Azm, and this study used a qualitative approach to data collection techniques: observation, interviews and documentary studies. The subject of the research is the school principal. The results of this study show that (1) the director implements a mentoring program whose purpose is to directly see the quality of teachers in teaching, (2) the director develops teacher quality by inviting external speakers and involving teachers in teaching. and study abroad. -academic seminars, (3) the teaching program is a very important program for the principal of Madarasah Tsanawiyah Nurul Azmi School, which has a positive effect on the students and teachers of the school. It can be said that the educational program made by the principal of Madrasah Tsanawiwyah Nurul Azmi is classified as optimal, although there are still mistakes in the implementation of the principals, in addition, the principal also provides opportunities. lecturers continued their studies at the university.
Metatranscriptomic Profiling of the Subgingival Microbiome in Peri-implantitis versus Healthy Implants: Identifying Key Dysbiotic Pathways Rheina Weisch Fedre; Ramakhrisnand Ramakhrisnand; Firman Hadi; Mahmood Abbas
Crown: Journal of Dentistry and Health Research Vol. 3 No. 1 (2025): Crown: Journal of Dentistry and Health Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/crown.v3i1.237

Abstract

Introduction: Peri-implantitis is a primary cause of dental implant failure, characterized by inflammatory destruction of supporting tissues. While microbial dysbiosis is implicated, the functional activities of the subgingival microbiome that drive disease pathogenesis remain poorly understood. This study aimed to elucidate the key functional and metabolic shifts in the subgingival microbiome associated with peri-implantitis using metatranscriptomic analysis. Methods: This cross-sectional study involved twenty patients, ten with healthy implants (HI) and ten diagnosed with peri-implantitis (PI). Subgingival biofilm samples were collected from the deepest peri-implant sulcus of each subject. Total RNA was extracted, followed by library preparation and sequencing on an Illumina NovaSeq platform. Bioinformatic analysis included quality control, taxonomic profiling using Kraken2, and functional annotation against the KEGG and Gene Ontology databases. Differential gene expression analysis was performed using DESeq2 to identify microbial transcriptional signatures distinguishing the PI and HI groups. Results: The metatranscriptome of the PI group exhibited significantly higher microbial diversity and a distinct taxonomic composition, with a notable enrichment of transcripts from species such as Porphyrononas gingivalis, Tannerella forsythia, and Fusobacterium nucleatum. In contrast, the HI group was dominated by transcripts from commensal streptococci. Functional analysis revealed a significant upregulation of pathways related to bacterial virulence, including lipopolysaccharide (LPS) biosynthesis, bacterial secretion systems (Type IV), and iron acquisition in the PI group. Furthermore, pathways associated with amino acid metabolism, particularly arginine and tryptophan degradation, were highly active, suggesting a proteolytic environment. Conversely, the HI metatranscriptome showed enrichment in carbohydrate metabolism and fermentation pathways. Conclusions: The subgingival microbiome in peri-implantitis is not only taxonomically distinct but also functionally primed for pathogenicity. The active transcription of genes related to virulence, inflammation induction, and proteolytic metabolism highlights the key dysbiotic pathways that likely contribute to tissue destruction. These findings provide a deeper understanding of the functional gene expression profile in peri-implantitis and suggest potential targets for future diagnostic and therapeutic strategies aimed at modulating microbial activity rather than merely eliminating specific taxa.
Biological Pathways of Oral Health Inequality: A Longitudinal Analysis of Stunting, Enamel Defects, and Salivary Immunity on Caries Trajectories in Indonesian Children Firman Hadi; Moon Kaeun; Fatimah Mursyid; Venny Melinda
Crown: Journal of Dentistry and Health Research Vol. 2 No. 2 (2024): Crown: Journal of Dentistry and Health Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/crown.v2i2.239

Abstract

Introduction: The syndemic of stunting and Early Childhood Caries (ECC) constitutes a major public health crisis in developing nations. While an association is established, the specific biological mechanisms remain poorly quantified. This study aimed to longitudinally determine the direct and indirect effects of early childhood stunting on caries increment, testing the mediating roles of enamel hypoplasia and salivary immunity after controlling for key confounders. Methods: We conducted a 3-year prospective cohort study of 542 two-year-old children in West Java, Indonesia. Stunting at baseline was defined as a height-for-age Z-score (HAZ) < -2 SD. The primary outcome was the 3-year increment in decayed, missing, and filled primary tooth surfaces (Δdmfs). Putative mediators—enamel hypoplasia and salivary secretory immunoglobulin A (s-IgA) and lactoferrin—were assessed. Longitudinal mixed-effects models and structural equation modeling (SEM) were used to analyze the pathways, adjusting for socio-demographic factors and fluoride exposure. Results: At baseline, 31.4% of children were stunted. After adjusting for confounders including fluoride exposure, stunting remained a powerful predictor of accelerated caries increment (an additional 1.95 surfaces/year; p<0.001). SEM analysis revealed the total effect of stunting on Δdmfs was substantial (Standardized β=0.45, p<0.001). This effect was significantly mediated by enamel hypoplasia (indirect effect β=0.17, accounting for 37.8% of total effect) and suppressed salivary s-IgA levels (indirect effect β=0.10, accounting for 22.2% of total effect). The direct effect of stunting, independent of these mediators, remained significant (β=0.18, p<0.001). Conclusion: Stunting in early life is a critical determinant of a high future caries burden, an effect that persists even after accounting for fluoride exposure. This relationship is substantially driven by two major biological pathways: compromised tooth structure (enamel hypoplasia) and impaired oral mucosal immunity (suppressed s-IgA). Public health strategies must integrate nutritional support within the first 1,000 days of life with oral health promotion to disrupt these pathways and combat the dual burden of stunting and ECC.
Co-Authors Abu Bakar Aisyah Oktaviana Aleisha Wulandari Andhika Kurnianta Kusuma Annisa Annisa Annisa Hananiyah Aprilia Sari Azhari Panjaitan Bandi Sasmito Cantika Amalia Devi Nilam Sari Fara Nabila Tania Fatimah Mursyid Indah Mayasari indra indra Inom Nasution Lestari Retnawati Mahmood Abbas Mariette Jackson Melin Andilla Moon Kaeun Muhammad Ashraf Nadhilah Ajrina Nia Saurina Ramakhrisnand Ramakhrisnand Raudhatul Jannah Rheina Weisch Fedre Siti Arafah E.N Siti Fatimah Azzahro Simatupang Sohyuk Kim Udik Pudjianto Utter Prakesh Venny Melinda Yi-Fen Huang Zulkifli M.Si